Flavones from the Bark of Lindera caudata and Their Anti-Tobacco Mosaic Virus Activity.

Two new flavones, 5-hydroxy-8-hydroxymethyl-7,4′-dimethoxy-flavone ( 1) and 6-hydroxy-8-hydroxymethyl-7,4′-dimethoxy-flavone ( 2), together with six known flavones ( 3-8), were isolated from the bark of Lindera caudata. The structures of 1-8 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1-8 were evaluated for their anti-tobacco mosaic virus (anti- TMV) activity. The results showed that Compounds 1 and 2 showed high anti- TMV activity with inhibition rates of 31.2 and 28.8%, respectively. These values are close to those of positive control. [ABSTRACT FROM AUTHOR]