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Concise synthesis of (+)-subersic acid from (−)-Sclareol.
- Source :
-
Tetrahedron . Jul2015, Vol. 71 Issue 28, p4647-4650. 4p. - Publication Year :
- 2015
-
Abstract
- A short and efficient synthesis of (+)-subersic acid in 6 steps with an overall yield of 8.6% from (−)-Sclareol was presented using Mitsunobu reaction and Claisen rearrangement as critical steps. This elegant protocol gave a convenient access to gram scales of (+)-subersic acid, which could be a precursor for its structural analogues and for further bioactivity researches. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 71
- Issue :
- 28
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 103087326
- Full Text :
- https://doi.org/10.1016/j.tet.2015.04.100