A novel mechanism for the acquisition of virulence by a human influenza A virus.

Authors :: Goto, Hideo
Kawaoka, Yoshihiro
Source :: Proceedings of the National Academy of Sciences of the United States of America. 08/18/98, Vol. 95 Issue 17, p10224. 5p. 6 Diagrams, 3 Charts, 7 Graphs.
Publication Year :: 1998
Abstract: Presents a mechanism of the hemagglutinin (HA) cleavage for a descendant of the 1918 pandemic strain of human influenza virus. Suggestion that the protein neuraminidase binds and sequesters plasminogen; Description of research methods utilized; Details on the determination of HA cleavage and polykaryon formation; Conclusions of this research.

Language :: English
ISSN :: 00278424
Volume :: 95
Issue :: 17
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 1028525
Full Text :: https://doi.org/10.1073/pnas.95.17.10224

Full Text Access

Tools