Metal–organic framework biosensor with high stability and selectivity in a bio-mimic environment.

A water-stable copper metal–organic framework (MOF), {[Cu2(HL)2(μ2-OH)2(H2O)5]·H2O}n (1, H2L = 2,5-dicarboxylic acid-3,4-ethylene dioxythiophene), was applied for the electrochemical detection of ascorbic acid (AA) without further post-modification. A glass carbon electrode covered with 1 was used as a biosensor for the simultaneous detection of AA and l-tryptophan (l-Trp) from both a single-component solution and a bio-mimic environment. [ABSTRACT FROM AUTHOR]