ASSESSMENT OF THE METABOLIC STATUS OF COWS IN EARLY LACTATION BY EXTRACTION OF DATA FROM METABOLIC, ENDOCRINE AND HEMATOLOGICAL PROFILE OF COWS -- RATIONAL DIAGNOSTIC.

Investigation of the metabolic status of cows in early lactation is the most important measure in assessing the health and productivity of cattle. Today, the analysis of metabolites, hormones and blood in the early lactation can be largely predicted health risk and of cows productivity. The daily work of veterinarians are available to a large number of markers in the blood that indicate the energy balance (NEFA, BHB, glucose), the balance of proteins (albumin, total protein, urea), the balance of ions (Ca, P, Mg), inflammatory response (blood pictures, inflammatory proteins), oxidative status (SOD, MDA), status of the liver (bilirubin, AST, ALT), hormonal (insulin, cortisol, IGF-I, STH, T3, T4) and hematology finding. In addition to the assessment of the metabolic status must be considered body condition of the cows and the amount of milk production. The aim of this study was to investigate the correlation between these parameters and to determine what parameters by whose determination can be seen overall metabolic status of cows. In this way we will make the extraction of information from large amounts of data, so we will focus only on those elements of the metabolic and endocrine profile that has the most reliable to describe the metabolic status of cows . In this way we will make the rationalization of laboratory testing metabolism cows. Blood was taken from 50 cows of the Holstein - Friesian breed. The concentration of the above- mentioned parameters were determined. They are made of the correlation matrix and then by extraction of the main factors using factor analysis. The results show that the extract may by three main factors. Factor 1 explains 61.7% of the variation, and it highly correlates with the values of insulin, IGF-I, STH, NEFA and glucose (metabolic stress). Factor 2 explains 20.2% of variation and on highly correlated with the BHB, AST, triglycerides and cholesterol (a liver). Factor 3, which explained 7% of the variation variables correlated with milk production in cows (productivity). [ABSTRACT FROM AUTHOR]