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Depressive symptoms are associated with incident coronary heart disease or revascularization among blacks but not among whites in the Reasons for Geographical and Racial Differences in Stroke study.
- Source :
-
Annals of Epidemiology . Jun2015, Vol. 25 Issue 6, p426-432. 7p. - Publication Year :
- 2015
-
Abstract
- Purpose To examine the association of depressive symptoms with coronary heart disease (CHD) end points by race and income. Methods Study participants were blacks and whites ( n = 24,443) without CHD at baseline from the national Reasons for Geographical and Racial Differences in Stroke cohort. Outcomes included acute CHD and CHD or revascularization. We estimated race-stratified multivariate Cox proportional hazards models of incident CHD and incident CHD or revascularization with the 4-item Center for Epidemiological Studies Depression Scale, adjusting for risk factors. Results Mean follow-up was 4.2 ± 1.5 years; CHD incidence was 8.3 events per 1000 person-years ( n = 366) among blacks and 8.8 events per 1000 person-years ( n = 613) among whites. After adjustment for age, sex, marital status, region, and socioeconomic status, depressive symptoms were significantly associated with incident CHD among blacks (hazard ratio [HR], 1.39; 95% confidence interval [CI], 1.00–1.91) but not among whites (HR, 1.10; 95% CI, 0.74–1.64). In the fully adjusted model, compared with blacks who reported no depressive symptoms, those reporting depressive symptoms had greater risk for the composite end point of CHD or revascularization (HR, 1.36; 95% CI, 1.01–1.81). Depressive symptoms were not associated with incident CHD end points among whites. Conclusions High depressive symptoms were associated with higher risk of CHD or revascularization for blacks but not whites. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10472797
- Volume :
- 25
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Annals of Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 102642867
- Full Text :
- https://doi.org/10.1016/j.annepidem.2015.03.014