Pro-inflammatory cytokines for evaluation of inflammatory status in endometriosis.

The aim of the study was to investigate the serum pro-inflammatory cytokine profile in patients with diagnosed endometriosis. Material and methods: The study included 160 women, who were divided in two study groups (Group I - endometriosis; Group 2 - healthy). We evaluated the serum levels of interleukin (IL)-lß, lL-5, IL-6, IL-7, and IL-12, and of tumour necrosis factor a (TNF-a) with the use of Human Multiplex Cytokine Panels. Conclusions: Women with endometriosis have elevated levels of key pro-inflammatory cytokines, i.e. IL-1β, IL-6, and TNF-a. At the same time, IL-1ß and IL-6 could be used as predictors for endometriosis. [ABSTRACT FROM AUTHOR]