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Iron(II)-Promoted Synthesis of 2-Aminothiazoles via C--N Bond Formation from Vinyl Azides and Potassium Thiocyanate.
Iron(II)-Promoted Synthesis of 2-Aminothiazoles via C--N Bond Formation from Vinyl Azides and Potassium Thiocyanate.
- Source :
-
Advanced Synthesis & Catalysis . Mar2015, Vol. 357 Issue 5, p1065-1069. 5p. - Publication Year :
- 2015
-
Abstract
- A simple protocol to prepare the privileged 2-aminothiazoles promoted by ferrous sulfate heptahydrate via C-N bond formation from vinyl azides and commercially available potassium thiocyanate has been developed. A wide range of vinyl azides are tolerated to afford the expected polysubstituted 2-aminothiazoles in reasonably good yields. The use of the non-toxic substrates and catalyst renders the reaction more environmentally friendly than traditional approaches. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 357
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 102376798
- Full Text :
- https://doi.org/10.1002/adsc.201400856