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Enhanced Detection of Human Immunodeficiency Virus Type 1- Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequence.

Authors :
Altfeld, Marcus
Addo, Marylyn M.
Shankarappa, Raj
Lee, Paul K.
Allen, Todd M.
Yu, Xu G.
Rathod, Almas
Harlow, Jason
O'Sullivan, Kristin
Johnston, Mary N.
Goulder, Philip J.R.
Mullins, James I.
Rosenberg, Eric S.
Korber, Christian
Walker, Bruce D.
Source :
Journal of Virology. Jul2003, Vol. 77 Issue 13, p7330. 11p. 2 Diagrams, 1 Chart, 15 Graphs.
Publication Year :
2003

Abstract

Examines the impact of antigen variability on the characterization of HIV type 1 (HIV-1)-specific T-cell responses by using an HIV-1 database. Use of autologous peptides; Gamma interferon Elispot analysis of HIV-1 class B-specific T-cell responses; Assessment of T-cell responses.

Subjects

Subjects :
*ANTIGENS
*T cells
*HIV

Details

Language :
English
ISSN :
0022538X
Volume :
77
Issue :
13
Database :
Academic Search Index
Journal :
Journal of Virology
Publication Type :
Academic Journal
Accession number :
10224445
Full Text :
https://doi.org/10.1128/JVI.77.13.7330-7340.2003