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Clozapine-Induced Myocarditis: Recognizing a Potentially Fatal Adverse Reaction.
- Source :
-
Texas Heart Institute Journal . Apr2015, Vol. 42 Issue 2, p155-157. 3p. 1 Black and White Photograph. - Publication Year :
- 2015
-
Abstract
- A 46-year-old man with a history of paranoid schizophrenia was admitted with a recurrence of psychotic symptoms. Improvement was noted after the initiation of clozapine. After 2 weeks of clozapine therapy, chest pressure and abnormal cardiac biomarkers (in the presence of a normal coronary angiogram) raised suspicion of myocarditis. That diagnosis was confirmed by means of cardiac magnetic resonance imaging. Discontinuation of the clozapine led to resolution of the cardiac symptoms. Clozapine-induced myocarditis is rare and can be missed for lack of specific clinical findings. In order to prevent disease progression and a possibly fatal outcome, early recognition of the condition and prompt discontinuation of clozapine are necessary. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CLOZAPINE
*ANTIDEPRESSANTS
*MYOCARDITIS
*CARDIOMYOPATHIES
*MYOSITIS
Subjects
Details
- Language :
- English
- ISSN :
- 15266702
- Volume :
- 42
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Texas Heart Institute Journal
- Publication Type :
- Academic Journal
- Accession number :
- 101962518
- Full Text :
- https://doi.org/10.14503/THIJ-13-3633