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Solvability analysis and numerical approximation of linearized cardiac electromechanics.
- Source :
-
Mathematical Models & Methods in Applied Sciences . May2015, Vol. 25 Issue 5, p959-993. 35p. - Publication Year :
- 2015
-
Abstract
- This paper is concerned with the mathematical analysis of a coupled elliptic-parabolic system modeling the interaction between the propagation of electric potential and subsequent deformation of the cardiac tissue. The problem consists in a reaction-diffusion system governing the dynamics of ionic quantities, intra- and extra-cellular potentials, and the linearized elasticity equations are adopted to describe the motion of an incompressible material. The coupling between muscle contraction, biochemical reactions and electric activity is introduced with a so-called active strain decomposition framework, where the material gradient of deformation is split into an active (electrophysiology-dependent) part and an elastic (passive) one. Under the assumption of linearized elastic behavior and a truncation of the updated nonlinear diffusivities, we prove existence of weak solutions to the underlying coupled reaction-diffusion system and uniqueness of regular solutions. The proof of existence is based on a combination of parabolic regularization, the Faedo-Galerkin method, and the monotonicity-compactness method of Lions. A finite element formulation is also introduced, for which we establish existence of discrete solutions and show convergence to a weak solution of the original problem. We close with a numerical example illustrating the convergence of the method and some features of the model. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02182025
- Volume :
- 25
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Mathematical Models & Methods in Applied Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 101421923
- Full Text :
- https://doi.org/10.1142/S0218202515500244