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ChemInform Abstract: 2-Pyridyl Thiazoles as Novel anti-Trypanosoma cruzi Agents: Structural Design, Synthesis and Pharmacological Evaluation.

Authors :
de Oliveira Cardoso, Marcos Verissimo
et al., et al.
Source :
ChemInform. Mar2015, Vol. 46 Issue 12, pno-no. 1p.
Publication Year :
2015

Abstract

The majority of new compounds (III) and (V) are potent cruzain inhibitors and show similar or greater trypanocidal efficacy than standard drug benznidazole, used for treatment of Chagas disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09317597
Volume :
46
Issue :
12
Database :
Academic Search Index
Journal :
ChemInform
Publication Type :
Academic Journal
Accession number :
101363715
Full Text :
https://doi.org/10.1002/chin.201512188