An update on the genetics of Gilles de la Tourette syndrome

<bold>Objectives: </bold>To summarize the current data suggesting that Gilles de la Tourette syndrome (GTS) is inherited and genetic.<bold>Methods: </bold>The extant literature on family studies, segregation analyses, candidate genes studies and linkage studies of GTS was reviewed and summarized.<bold>Results and Conclusions: </bold>There is considerable data that suggests that: (1). genetic factors play an important role in the manifestation of GTS; (2). several genes are important with some possibly having major effect; and (3). several regions of the genome have been identified as potential locations of these susceptibility genes. [ABSTRACT FROM AUTHOR]