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Ruthenium-catalyzed aerobic oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes: a new route to isoquinolones.

Authors :
Reddy, Mallu Chenna
Manikandan, Rajendran
Jeganmohan, Masilamani
Source :
Chemical Communications. 2013, Vol. 49 Issue 54, p6060-6062. 3p.
Publication Year :
2013

Abstract

The oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes in the presence of a catalytic amount of [{RuCl2(p-cymene)}2], Cu(OAc)2·H2O and KPF6 in acetic acid under air gave isoquinolones in good to excellent yields. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
49
Issue :
54
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
100899623
Full Text :
https://doi.org/10.1039/c3cc42683a