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Replacement of dichloromethane within chromatographic purification: a guide to alternative solvents.
- Source :
-
Green Chemistry . 2012, Vol. 14 Issue 11, p3016-3019. 4p. - Publication Year :
- 2012
-
Abstract
- Replacement of dichloromethane as the bulk medium within chromatographic purification has been evaluated with a broad range of molecules containing functionality common within Medicinal Chemistry programmes. Analysis of the data set has generated a set of general guidelines to assist in the selection of alternative solvents for CH2Cl2 as the bulk media in these ubiquitously employed processes. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14639262
- Volume :
- 14
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Green Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 100867659
- Full Text :
- https://doi.org/10.1039/c2gc36378j