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Assembly of Indoline-2-carboxylate-Embodied Dipeptidesvia Pd-Catalyzed C(sp2)–H Bond Direct Functionalization.

Authors :
He, Yu-Peng
Zhang, Chao
Fan, Mengyang
Wu, Zhijie
Ma, Dawei
Source :
Organic Letters. Feb2015, Vol. 17 Issue 3, p496-499. 4p.
Publication Year :
2015

Abstract

Intramolecular dehydrogenative cyclizationof 2-methoxyiminoacyl-protectedphenylalanine derivatives proceeded at 110 °C under catalysisof Pd(OAc)2in the presence of 1-fluoro-2,4,6-trimethylpyridiniumtetrafluoroborate to afford substituted indoline-2-carboxylates thatwere converted into indoline-2-carboxylate-embodied dipeptides viaRaney Ni-catalyzed hydrogenation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15237060
Volume :
17
Issue :
3
Database :
Academic Search Index
Journal :
Organic Letters
Publication Type :
Academic Journal
Accession number :
100857471
Full Text :
https://doi.org/10.1021/ol503514t