Self-stigma as a mediator between social capital and empowerment among people with major depressive disorder in Europe: The ASPEN study.

Introduction Individual social capital has been recognized as having an important role for health and well-being. We tested the hypothesis that poor social capital increases internalized stigma and, in turn, can reduce empowerment among people with major depressive disorder (MDD). Materials and methods This is a cross-sectional multisite study conducted on a sample of 516 people with MDD in 19 European countries. Structural Equation Models were developed to examine the direct and indirect effects of self-stigma and social capital on empowerment. Results Social capital and self-stigma accounted for 56% of the variability in empowerment. Higher social capital was related to lower self-stigma ( r = –0.72, P < 0.001) which, in turn, partially mediated the relationship between social capital and empowerment ( r = 0.38, P < 0.001). Conclusions Social capital plays a key role in the appraisal of empowerment, both directly and through the indirect effect mediated by self-stigma. In order to improve empowerment of people with MDD, we identify strategies to foster individual social capital, and to overcome the negative consequences related to self-stigma for attainment of life goals. [ABSTRACT FROM AUTHOR]