Aperient bowel function for rice isomalto-oligosaccharide.

The 8-week-old SPF class C57BL/6 male mice were used as experimental object, the compound diphenoxylate was adopted to establish the constipation model. At the same time, three groups were established maren pills positive control group, blank control group and rice isomalto-oligosaccharide low, medium, and high dose groups. The body weight change of experimental mice gavage before and after, the mice first defecation time, 8 h defecation number, 8 h defecation quality, 8 h defecation moisture content and small intestine propulsion rate were analyzed through single factor experiment. The results showed that there were significant differences between the constipation model group and positive control group, blank control group. Constipation model group was established successfully; rice isomalto-oligosaccharide could shorten the mice first defecation time, improve 8 h defecation quality, 8 h defecation moisture content and small intestine propulsion rate, and the aperient bowel effect of medium dose group was better. [ABSTRACT FROM AUTHOR]