Protracted Fecal Shedding of HEV During Ribavirin Therapy Predicts Treatment Relapse.

Twenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy. [ABSTRACT FROM PUBLISHER]