Back to Search
Start Over
Enantioselective intramolecular propargylic amination using chiral copper-pybox complexes as catalysts.
- Source :
-
Chemical Communications . 2014, Vol. 50 Issue 58, p7874-7877. 4p. - Publication Year :
- 2014
-
Abstract
- Intramolecular propargylic amination of propargylic acetates bearing an amino group at the suitable position in the presence of chiral copperpybox complexes proceeds enantioselectively to give optically active 1-ethynyl-isoindolines (up to 98% ee). The method described in this communication provides a useful synthetic approach to the enantioselective preparation of nitrogen containing heterocyclic compounds with an ethynyl group at the a-position. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 50
- Issue :
- 58
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 100182273
- Full Text :
- https://doi.org/10.1039/c4cc01676a