Kozmetikler ve In Silico Yaklaşımlar.

Cosmetics and in silico approaches Emerging technologies with molecular modelling techniques give opportunity to discover the active ingredients in cosmetics by using rational methods. Using chemoinformatic methods provides information about the acquisition of cosmetic active molecules or groups. With these methods, the physicochemical properties, which are involved in the formulation design are better evaluated and the results can be obtained in a short time with comparative toxicity studies. Accordingly some computer programs, without any need to animal models have been developed for testing cosmetic active agents to investigate their efficacy and toxic effects in humans and provide their safe use. In this review, some well-known cosmetic active molecules from scientific articles, their effects, molecular mechanisms and rational design methods are given to describe the importance of molecular modelling in cosmetic innovations [ABSTRACT FROM AUTHOR]