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Enantioselective desymmetrization of prochiral 1,3-dinitropropanes via organocatalytic allylic alkylation.

Authors :
Singha Roy, Soumya Jyoti
Mukherjee, Santanu
Source :
Chemical Communications. 2014, Vol. 50 Issue 1, p121-123. 3p.
Publication Year :
2014

Abstract

An enantioselective desymmetrization of prochiral 1,3-dinitropropanes has been developed which proceeds via enantiogroup differentiating organocatalytic allylic alkylation. Densely functionalized products with two vicinal stereocenters were obtained generally with good to excellent diastereoselectivity (up to >20: 1 dr) and superb enantioselectivity (up to >99: 1 er). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
50
Issue :
1
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
100141552
Full Text :
https://doi.org/10.1039/c3cc47645f