Genoprotective and Genotoxic Effects of Thymoquinone on Doxorubicin-Induced Damage in Isolated Human Leukocytes.

Authors :: Al-Shdefat, Ramadan I.
Abd-ElAziz, Mohamed A.
Al-Saikhan, Fahad I.
Source :: Tropical Journal of Pharmaceutical Research. Dec2014, Vol. 13 Issue 12, p2015-2020. 6p.
Publication Year :: 2014
Abstract: Conclusion: TQ can be used as a genoprotective agent against DXR-induced genotoxicity. The dual behavior of TQ observed in this study is dose-dependent and therefore its mechanism of action needs to be clarified in future studies. [ABSTRACT FROM AUTHOR]

Subjects :: *GENETIC toxicology
*QUINONE
*DOXORUBICIN
*LEUCOCYTES
*OXIDATIVE stress

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