Chemical Constituents and Antibacterial activity of the Root Oil of Naregamia alata.

The essential oil obtained by hydrodistillation from the root of Naregamia alata was analyzed. Thirty four compounds were identified by mass spectral database search and comparison of linear retention indices. γ-Himachalene (11.2%), β-Caryophyllene (10.8%) and β-Sesquiphellandrene (10.7%) were the major constituents. The antibacterial activity of the root oil was studied by the disc diffusion assay. The oil showed significant antibacterial activity against Gram-positive and Gram-negative bacteria. This is the first report on the essential oil composition and antibacterial activity of N. alata. [ABSTRACT FROM AUTHOR]