The role of a specific antibody against Flavobacterium psychrophilum infection in ayu sweetfish, Plecoglossus altivelis altivelis ( Temminck & Schlegel, 1846).

The article explores the role of fish immunization agent as preventive medical protection against the Flavobacterium psychrophilum which causes bacterial cold-water disease (BCWD) among ayu sweetfishes. A historical overview about the development studies to prevent the spread of BCWD among fishes and salmonid fishes is noted. It conclude the importance of specific antibody production through increasing phagocytic and bactericidal activity of serum against F. psychrophilum in ayu fishes.