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1. Association of growth from birth until middle age with sex hormone parameters and reproductive function in the Northern Finland Birth cohort 1966

Author: Morin-Papunen, L. (Laure), Laru, J. (Johanna), Morin-Papunen, L. (Laure), and Laru, J. (Johanna)
Abstract: Obesity predisposes people to numerous morbidities and less well-known reproductive problems. In women, obesity increases the risk of infertility and polycystic ovary syndrome (PCOS). In men, obesity impairs reproductive health and is associated with testosterone (T) deficiency. Since the above-mentioned problems affect a significant proportion of the population, this study focuses on the association between early risk factors and reproductive problems, providing a great opportunity to identify the sensitive time periods for preventive actions. The aim of this study was to assess the impact of prenatal factors, birth weight (BW), and BMI, from birth until middle age, on sex hormone levels and reproductive function in both women and men. The study populations (women and men with impaired reproductive function, women with PCOS and men with low T at age 31) were derived from the Northern Finland Birth Cohort 1966 with additional data from the Finnish Medical Birth Register. Multiple confounding factors, such as socioeconomic and lifestyle factors, marital status, attempts to have children, and adult obesity, could be considered. The results revealed that in girls, obesity in mid-childhood and especially in puberty — and in boys, low BMI in early childhood — predicted impaired reproductive function, as well as an increased risk of childlessness regardless of confounding factors. In boys, overweight and obesity in early childhood was associated with a decreased risk of infertility, but BMI from mid-childhood onwards did not affect their subsequent reproductive function. Both women with PCOS and men with low T at age 31 already had higher weight gain from childhood onwards; their weight gain began earlier, and their BMIs remained higher until age 46. In boys, maternal obesity was associated significantly with later T deficiency, suggesting that metabolic factors during pregnancy affect boys’ endocrine function later in life. Lower BW and prematurity in girls were, Tiivistelmä Lihavuus aiheuttaa monien sairauksien lisäksi myös merkittäviä lisääntymisterveyden ongelmia ja lisää riskiä lapsettomuudelle. Lihavuus lisää naisilla munasarjojen monirakkulaoireyhtymän (PCOS) ja miehillä mieshormonivajeen riskiä. Nämä ongelmat koskettavat merkittävää osaa väestöstä. Tämä tutkimus antaa mahdollisuuden tunnistaa varhaisten riskitekijöiden yhteyksiä lisääntymisterveyden ongelmiin ja siten löytää keinoja oikea-aikaisiin ennaltaehkäiseviin toimiin. Tässä tutkimuksessa arvioitiin raskauden aikaisten tekijöiden, syntymäpainon ja painoindeksin (BMI) kehityksen vaikutusta hormonaalisiin muuttujiin ja lisääntymisterveyteen sekä naisilla että miehillä keski-ikään saakka. Tutkimuspopulaatiot (lapsettomuudesta kärsivät naiset ja miehet, PCOS-naiset sekä miehet, joilla todettiin mieshormonivaje 31-vuotiaana) koostuivat Pohjois-Suomen syntymäkohortista 1966, johon yhdistettiin Terveyden ja hyvinvoinninlaitoksen syntymärekisterin tietoja. Tutkimusaineisto mahdollisti useiden sekoittavien tekijöiden, kuten sosioekonomisen aseman, elintapojen, siviilisäädyn, lapsitoiveen ja aikuisiän lihavuuden, huomioimisen analyyseissa. Tutkimuksessa havaittiin, että keskilapsuuden ja murrosiän lihavuus tytöillä ja varhaislapsuuden matala BMI pojilla olivat yhteydessä lapsettomuusongelmiin ja riskiin jäädä myöhemmin lapsettomaksi siviilisäädystä riippumatta. Toisaalta poikien ylipaino ja lihavuus varhaislapsuudessa, mutta ei enää sen jälkeen, vähensivät lapsettomuusongelmien riskiä. Sekä PCOS-naisilla että 31-vuotiaana mieshormonivajeesta kärsivillä miehillä todettiin suurempi painon kertyminen jo varhaislapsuudessa, ja BMI pysyi korkeampana kuin kontrolleilla aina keski-ikään saakka. Pojilla äidin lihavuus liittyi merkittävästi itsenäisenä riskitekijänä myöhempään mieshormonivajeeseen viitaten siihen, että raskauden aikaiset aineenvaihdunnalliset tekijät vaikuttavat merkittävästi myöhempään hormonaalisen toimintaan. Tytöillä matalampi syntymäpaino ja ennenaikaisuus l
Published: 2023

2. Underweight and obesity are related to higher mortality in patients undergoing coronary angiography: The KARDIO invasive cardiology register study

Author: Laukkanen, Jari A., Kunutsor, Setor K., Hernesniemi, Jussi, Immonen, Jaakko, Eskola, Markku, Zaccardi, Francesco, Niemelä, Matti, Mäkikallio, Timo, Hagnäs, Magnus, Piuhola, Jarkko, Juvonen, Jukka, Rummukainen, Juha, Sia, Jussi, Kervinen, Kari, Karvanen, Juha, Nikus, Kjell, KARDIO Study Group, Tampere University, Clinical Medicine, and TAYS Heart Centre
Subjects: kuolleisuus, väestötutkimus, alipainoisuus, Cardiology, body mass index, Coronary Angiography, 3121 Internal medicine, Body Mass Index, Thinness, varjoainetutkimus, Risk Factors, Humans, angiography, Radiology, Nuclear Medicine and imaging, Obesity, painoindeksi, ylipaino, General Medicine, mortality, Treatment Outcome, hospital register, Cardiovascular Diseases, sepelvaltimotauti, sydän- ja verisuonitaudit, lihavuus, seurantatutkimus, Cardiology and Cardiovascular Medicine, coronary artery disease
Abstract: Background: In patients with some cardiovascular disease conditions, slightly elevated body mass index (BMI) is associated with a lower mortality risk (termed “obesity paradox”). It is uncertain, however, if this obesity paradox exists in patients who have had invasive cardiology procedures. We evaluated the association between BMI and mortality in patients who underwent coronary angiography. Methods: We utilised the KARDIO registry, which comprised data on demographics, prevalent diseases, risk factors, coronary angiographies, and interventions on 42,636 patients. BMI was categorised based on WHO cut-offs or transformed using P-splines. Hazard ratios (HRs) with 95% confidence intervals (CIs) were estimated for all-cause mortality. Results: During a median follow-up of 4.9 years, 4688 all-cause deaths occurred. BMI was nonlinearly associated with mortality risk: compared to normal weight category (18.5–25 kg/m2), the age-adjusted HRs (95% CIs) for all-cause mortality were 1.90 (1.49, 2.43), 0.96 (0.92, 1.01), 1.04 (0.99, 1.09), 1.08 (0.96, 1.20), and 1.45 (1.22, 1.72) for underweight (40 kg/m2), respectively. The corresponding multivariable adjusted HRs (95% CIs) were 2.00 (1.55, 2.58), 0.92 (0.88, 0.97) 1.01 (0.95, 1.06), 1.10 (0.98, 1.23), and 1.49 (1.26, 1,78), respectively. Conclusions: In patients undergoing coronary angiography, underweight and obesity class III are associated with increased mortality risk, and the lowest mortality was observed in the preobesity class. It appears the obesity paradox may be present in patients who undergo invasive coronary procedures. publishedVersion
Published: 2022
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3. Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?

Author: Eero A. Haapala, Tuomo Tompuri, Niina Lintu, Anna Viitasalo, Kai Savonen, Timo A. Lakka, and Jari A. Laukkanen
Subjects: Male, Adult, obesity, kolesteroli, lastentautioppi, Blood Pressure, lapset (ikäryhmät), Physical Therapy, Sports Therapy and Rehabilitation, HDL-kolesteroli, metabolic syndrome, paediatrics, aineenvaihduntahäiriöt, Risk Factors, insulin resistance, terveysvaikutukset, Humans, Insulin, Orthopedics and Sports Medicine, LDL-kolesteroli, Child, metabolinen oireyhtymä, Triglycerides, aikuiset, kunto, kehonkoostumus, Metabolic Syndrome, body composition, Cholesterol, HDL, ylipaino, riskitekijät, insuliiniresistenssi, fitness, mittausmenetelmät, Cross-Sectional Studies, Cardiorespiratory Fitness, Cardiovascular Diseases, Physical Fitness, lihavuus, Female, ennaltaehkäisy, Insulin Resistance
Abstract: Objectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors. Design Cross-sectional. Methods A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total fat free mass (FFM−1), and allometrically modelled BM, FFM, and stature. Insulin, glucose, triglycerides, HDL cholesterol, and LDL cholesterol were assessed from fasting blood samples and systolic and diastolic blood pressure were measured. HOMA-IR and continuous metabolic risk score were computed. Results V̇O2peak scaled by BM−1 was inversely associated with insulin, HOMA-IR, triglycerides, diastolic blood pressure, the cardiometabolic risk score and the number of cardiometabolic risk factors in children and adults. However, these associations attenuated remarkably when V̇O2peak was scaled by total FFM or allometrically modelled BM, FFM, or stature. V̇O2peak was consistently and positively associated with HDL cholesterol in children and adults irrespective of the scaling approach. Conclusions The inverse associations of CRF with cardiometabolic risk factors among children and adults attenuated remarkably when body size and composition were appropriately controlled for. However, the positive association between CRF and HDL cholesterol was consistent irrespective of the scaling approach. peerReviewed
Published: 2022
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4. Association of growth from birth until middle age with sex hormone parameters and reproductive function in the Northern Finland Birth cohort 1966

Author: Laru, J. (Johanna) and Morin-Papunen, L. (Laure)
Subjects: obesity, munasarjojen monirakkulatauti, alipainoisuus, male hypogonadism, lapsettomuus, birth weight, ylipaino, androgen, lisääntymisterveys, lapsuusiän kasvu, mieshormonivaje, childlessness, underweight, adiposity rebound, childhood growth, painon kehitys, PCOS, overweight, lihavuus, reproductive function, infertility, hedelmällisyys, androgeenit
Abstract: Obesity predisposes people to numerous morbidities and less well-known reproductive problems. In women, obesity increases the risk of infertility and polycystic ovary syndrome (PCOS). In men, obesity impairs reproductive health and is associated with testosterone (T) deficiency. Since the above-mentioned problems affect a significant proportion of the population, this study focuses on the association between early risk factors and reproductive problems, providing a great opportunity to identify the sensitive time periods for preventive actions. The aim of this study was to assess the impact of prenatal factors, birth weight (BW), and BMI, from birth until middle age, on sex hormone levels and reproductive function in both women and men. The study populations (women and men with impaired reproductive function, women with PCOS and men with low T at age 31) were derived from the Northern Finland Birth Cohort 1966 with additional data from the Finnish Medical Birth Register. Multiple confounding factors, such as socioeconomic and lifestyle factors, marital status, attempts to have children, and adult obesity, could be considered. The results revealed that in girls, obesity in mid-childhood and especially in puberty — and in boys, low BMI in early childhood — predicted impaired reproductive function, as well as an increased risk of childlessness regardless of confounding factors. In boys, overweight and obesity in early childhood was associated with a decreased risk of infertility, but BMI from mid-childhood onwards did not affect their subsequent reproductive function. Both women with PCOS and men with low T at age 31 already had higher weight gain from childhood onwards; their weight gain began earlier, and their BMIs remained higher until age 46. In boys, maternal obesity was associated significantly with later T deficiency, suggesting that metabolic factors during pregnancy affect boys’ endocrine function later in life. Lower BW and prematurity in girls were associated with PCOS later in life. Given the well-known health risks related to obesity and the steadily rising prevalence of maternal obesity, the study results emphasize the importance of preventing obesity, maintaining an optimal growth during childhood, and preventing maternal obesity, as all these factors affect reproductive health later in life. Tiivistelmä Lihavuus aiheuttaa monien sairauksien lisäksi myös merkittäviä lisääntymisterveyden ongelmia ja lisää riskiä lapsettomuudelle. Lihavuus lisää naisilla munasarjojen monirakkulaoireyhtymän (PCOS) ja miehillä mieshormonivajeen riskiä. Nämä ongelmat koskettavat merkittävää osaa väestöstä. Tämä tutkimus antaa mahdollisuuden tunnistaa varhaisten riskitekijöiden yhteyksiä lisääntymisterveyden ongelmiin ja siten löytää keinoja oikea-aikaisiin ennaltaehkäiseviin toimiin. Tässä tutkimuksessa arvioitiin raskauden aikaisten tekijöiden, syntymäpainon ja painoindeksin (BMI) kehityksen vaikutusta hormonaalisiin muuttujiin ja lisääntymisterveyteen sekä naisilla että miehillä keski-ikään saakka. Tutkimuspopulaatiot (lapsettomuudesta kärsivät naiset ja miehet, PCOS-naiset sekä miehet, joilla todettiin mieshormonivaje 31-vuotiaana) koostuivat Pohjois-Suomen syntymäkohortista 1966, johon yhdistettiin Terveyden ja hyvinvoinninlaitoksen syntymärekisterin tietoja. Tutkimusaineisto mahdollisti useiden sekoittavien tekijöiden, kuten sosioekonomisen aseman, elintapojen, siviilisäädyn, lapsitoiveen ja aikuisiän lihavuuden, huomioimisen analyyseissa. Tutkimuksessa havaittiin, että keskilapsuuden ja murrosiän lihavuus tytöillä ja varhaislapsuuden matala BMI pojilla olivat yhteydessä lapsettomuusongelmiin ja riskiin jäädä myöhemmin lapsettomaksi siviilisäädystä riippumatta. Toisaalta poikien ylipaino ja lihavuus varhaislapsuudessa, mutta ei enää sen jälkeen, vähensivät lapsettomuusongelmien riskiä. Sekä PCOS-naisilla että 31-vuotiaana mieshormonivajeesta kärsivillä miehillä todettiin suurempi painon kertyminen jo varhaislapsuudessa, ja BMI pysyi korkeampana kuin kontrolleilla aina keski-ikään saakka. Pojilla äidin lihavuus liittyi merkittävästi itsenäisenä riskitekijänä myöhempään mieshormonivajeeseen viitaten siihen, että raskauden aikaiset aineenvaihdunnalliset tekijät vaikuttavat merkittävästi myöhempään hormonaalisen toimintaan. Tytöillä matalampi syntymäpaino ja ennenaikaisuus lisäsivät riskiä PCOS:lle. Tämän tutkimuksen tulokset korostavat synnyttäjien ylipainon ja lapsuusiän lihavuuden ehkäisemisen sekä optimaalisen kasvun tukemisen tärkeyttä, varsinkin kun otetaan huomioon lihavuuteen liittyvät muut terveysriskit ja synnyttäjien ylipainon jatkuva lisääntyminen, koska nämä kaikki vaikuttavat myöhempään lisääntymisterveyteen.
Published: 2023

5. The association between food consumption and visceral fat in 7- and 9-year-old children

Author: Oksanen, Essi, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kansanterveystiede ja kliininen ravitsemustiede, Faculty of Health Sciences, School of Medicine, Public Health and Clinical Nutrition, Terveystieteiden tiedekunta, and Faculty of Health Sciences
Subjects: ravinto, Terveysvaikutukset, ruoka-aineet, lihavuus, ravitsemustiede, ylipaino, nutrition science, ravitsemus, terveys, lapset
Published: 2023

6. Neuvolan terveydenhoitajat raskaana olevien ja lasten painonhallinnan tukena.

Author: MÄENPÄÄ, TIINA and VUORI, ANNE
Subjects: PREVENTION of obesity, REGULATION of body weight, CHILD health services, COMMUNITY health nursing, COMMUNITY health services, CONTENT analysis, INTEGRATED health care delivery, NURSES, QUALITATIVE research, OCCUPATIONAL roles, SOCIAL support, SPECIALTY hospitals, CHILDREN, PREGNANCY
Abstract: Copyright of Hoitotiede is the property of Hoitotieteiden Tutkimusseura HTTS r.y. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Published: 2019

7. The association between parental background and eating behaviour in overweight children at age 6-12 years

Author: Sonko, Jessica, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kansanterveystiede ja kliininen ravitsemustiede, Faculty of Health Sciences, School of Medicine, Public Health and Clinical Nutrition, Terveystieteiden tiedekunta, and Faculty of Health Sciences
Subjects: obesity, diabetes, children (age groups), painohistoria, lapset (ikäryhmät), ylipaino, CEBQ, ruokavaliot, sosioekonominen asema, ras-kausajan diabetes, socioeconomic status, socioekonomisk ställning, diets, ravitsemustiede, lihavuus, overweight, dieter, nutrition science, övervikt, fetma, barn (åldersgrupper), Lasten syömiskäyttäytyminen, lapsuusiän ylipaino
Published: 2023

8. Association of indolepropionic acid and depression symptoms among middle-aged men and women

Author: Siekkinen, Milla, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kansanterveystiede ja kliininen ravitsemustiede, Faculty of Health Sciences, School of Medicine, Public Health and Clinical Nutrition, Terveystieteiden tiedekunta, and Faculty of Health Sciences
Subjects: masennus, obesity, medicine, gastrointestinal microbiota, diabetes, suolistomikrobisto, depression (mental disorders), näring (nutrition), ylipaino, lääketiede, riskitekijät, Ravitsemus, depression, ravintokuitu, lihavuus, risk factors, overweight, riskfaktorer, tarmflora, dietetics, övervikt, fetma
Published: 2023

9. Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

Author: Helena A. K. Lapatto, Minna Kuusela, Aino Heikkinen, Maheswary Muniandy, Birgitta W. van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S. Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka Katajisto, Marko Lehtonen, Charles Brenner, Jaakko Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H. Pietiläinen, Eija Pirinen, Centre of Excellence in Stem Cell Metabolism, CAMM - Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, Institute for Molecular Medicine Finland, Helsinki Institute of Life Science HiLIFE, Molecular and Integrative Biosciences Research Programme, Institute of Biotechnology, HUS Medical Imaging Center, Clinicum, HUS Abdominal Center, II kirurgian klinikka, Marja-Riitta Taskinen Research Group, Research Programs Unit, Department of Medicine, Per Henrik Groop / Principal Investigator, Medicum, Nefrologian yksikkö, Department of Biochemistry and Developmental Biology, and Eija Pirinen / Principal Investigator
Subjects: 11832 Microbiology and virology, Multidisciplinary, Dna methylation, Skeletal-muscle, Supplementation, mitokondriot, Nad(+), ylipaino, Niacin, Faecalibacterium-prausnitzii, aineenvaihduntahäiriöt, High-fat diet, Metabolism, suolisto, Liver, Adipose-tissue, terveysvaikutukset, lihavuus, 3111 Biomedicine, aineenvaihdunta
Abstract: Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial dysfunction and metabolic syndrome in mice. However, most short-term clinical trials conducted so far have not reported positive outcomes. Therefore, we aimed to determine whether long-term NR supplementation boosts mitochondrial biogenesis and metabolic health in humans. Twenty body mass index (BMI)–discordant monozygotic twin pairs were supplemented with an escalating dose of NR (250 to 1000 mg/day) for 5 months. NR improved systemic NAD + metabolism, muscle mitochondrial number, myoblast differentiation, and gut microbiota composition in both cotwins. NR also showed a capacity to modulate epigenetic control of gene expression in muscle and adipose tissue in both cotwins. However, NR did not ameliorate adiposity or metabolic health. Overall, our results suggest that NR acts as a potent modifier of NAD + metabolism, muscle mitochondrial biogenesis and stem cell function, gut microbiota, and DNA methylation in humans irrespective of BMI.
Published: 2023
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10. Kehonpainoindeksin vaikutus kokemukseen omasta terveydestä sekä elämäntapaneuvonnasta ja vaikutus terveyspalveluiden käyttöön : Health and social support -tutkimus 2012

Author: Kotisaari, Anni, Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology, and Tampere University
Subjects: terveyspalvelut, terveydentila, Lääketieteen lisensiaatin tutkinto-ohjelma - Licentiate's Programme in Medicine, lihavuus, ylipaino, painoindeksi
Abstract: Suomalaisesta aikuisväestöstä suuri osa on ylipainoisia. Aikuinen henkilö katsotaan ylipainoiseksi, jos hänen kehonpainoindeksinsä on yli 25 kg/m2. Ylipaino lisää riskiä sairastua useisiin sairauksiin, ja siihen on tutkimuksissa liitetty huonompi koettu elämänlaatu. Myös ylipainoon liittyvää syrjintää esiintyy sekä terveydenhuollossa että jokapäiväisessä elämässä. Tässä tutkimuksessa tarkastellaan, onko kehonpainoindeksillä vaikutusta henkilön kokemukseen terveydentilasta, terveyspalveluiden käyttöön tai kokemukseen elämäntapaneuvonnasta. Terveyspalveluiden käytön osalta tutkitaan kuinka suuri osa ali- ja normaalipainoisista ja ylipainoisista ei ollut käynyt vastaanotoilla kertaakaan vuoden aikana ja kuinka suuri osa kävi kaksi kertaa tai enemmän. Aineistona käytetään vuonna 2012 kerättyä Health and Social Support -tutkimuksesta kerättyä aineistoa. Aineisto on kerätty kyselytutkimuksena, ja vuonna 2012 siihen vastanneita oli 15 993. Tutkittavia yhteyksiä tarkastellaan ristiintaulukoinnilla ja khiin neliön testillä. Havaitaan, että ylipainolla on vaikutusta siihen, miten henkilö kokee oman terveydentilansa. Ylipainoisista pienempi osa kokee terveydentilansa hyväksi verrattuna ali- ja normaalipainoisiin. Ali- ja normaalipainoisista terveydentilansa koki hyväksi tai melko hyväksi 85 % ja ylipainoista 70 %. Terveyspalveluiden käytössä ylipainolla on vaikutusta etenkin terveyskeskuslääkärillä ja sairaalan poliklinikalla tapahtuneisiin käynteihin, joissa ali- ja normaalipainoisista suurempi osa ei ollut käynyt terveyskeskuslääkärillä ja sairaalan poliklinikalla kertaakaan vuoden aikana verrattuna ylipainoisiin. Useampia käyntejä on ylipainoisilla enemmän terveyskeskuslääkärin vastaanotolla, työterveydessä ja sairaalan poliklinikalla. Ali- ja normaalipainoisilla useampia käyntejä on enemmän yksityislääkärin vastaanotolla ja hammaslääkärissä. Tapaturman vuoksi tapahtuneissa käynneissä erot olivat hyvin pieniä. Elämäntapaohjaukseen suhtautumisessa ylipainoisista suurempi osa koki lääkärin antamalla ohjauksella olevan hyvin paljon tai melko paljon vaikutusta. Sen sijaan ali- ja normaalipainoisista suurempi osa, 25 %, koki ettei ohjauksella ole heihin kovin paljon tai ollenkaan vaikutusta, kun ylipainoisilla osuus oli 18 %. Tutkimus osoittaa, että ylipainolla on vaikutusta sekä terveyspalveluiden käyttöön että kokemukseen terveydestä ja annetusta ohjauksesta. Jotta kansanterveydellisenä haasteena olevaa ylipainoa voitaisiin pystyä paremmin hoitamaan, on tärkeää tietää miten se vaikuttaa henkilön kokemuksiin. Terveyspalveluiden tehostamisen kannalta tarvitaan tietoa, onko ylipainoisten terveyspalveluita syytä tehostaa.
Published: 2023

11. Kohti eettistä ja vastuullista painopuhetta ja -käytäntöjä : lihavuuden stigma ja sen vähentäminen

Author: Koivumäki, Terhi, Harjunen, Hannele, Hagström, Tiia, Mikkilä, Katri, Pusa, Tuija, and Lahti-Koski, Marjaana
Subjects: research activities, obesity, yhdenvertaisuus, julkinen keskustelu, research, stigma, syrjintä, hyvinvointi, leimautuminen (sosiologia), lihavuus, ylipaino, terveyden edistäminen
Abstract: Tämä raportti esittää suositukset, tulokset ja tutkimusmenetelmät valtioneuvoston kanslian rahoittamassa Kohti eettistä ja vastuullista painopuhetta ja -käytäntöjä -hankkeessa. Hankkeen toteuttivat Suomen Sydänliitto ja Jyväskylän yliopisto, kumppaninaan Syömishäiriöliitto. Tulokset perustuvat tutkittuun tietoon lihavuuden stigmasta, kolmeen etukäteisaineistoon, hankkeen aikana järjestyttyihin työpajoihin (terveydenhuolto, liikunta, lihavuuden asiantuntijat, media, päättäjät) sekä media-analyysiin. Hankkeen aikana osallistuttiin aktiivisesti mediassa ja eri verkostoissa keskusteluun lihavuuden stigmasta. Lihavuuden stigman vaikutukset, erityisesti painoon liittyvä syrjintä, näkyvät kaikilla keskeisillä elämän alueilla yhteiskunnassamme. Olemassa olevat käytännöt, rakenteet ja prosessit tukevat paino-, ei hyvinvointikeskeistä tapaa toimia. Puhetapamme ja viestintämme lihavuudesta lisäävät lihavuuden stigmaa. Jotta edetään kohti eettistä ja vastuullista painopuhetta ja -käytäntöjä sekä vähennetään lihavuuden stigmasta johtuvia seurauksia, tarvitaan lisää tietoa ja ymmärrystä lihavuuden stigmasta koulutuksen, tutkimuksen ja arvotyöskentelyn keinoin. Lihavuuteen liittyvää viestintää on kehitettävä ja laadittava eettiset ohjeet lihavuudesta viestimiseen ja sen kuvittamiseen. Yhdenvertaisuuslakiin on lisättävä kielto syrjinnästä koon tai painon perusteella. This report presents the recommendations, results and research methods employed in a project funded by the Prime Minister’s Office titled “Towards ethical and responsible weight dialogue and practices”.The project was conducted by Finnish Heart Association and University of Jyväskylä in conjunction with Eating Disorder Association. The findings are based on research data obtained about obesity stigma, material from three previous studies, workshops (healthcare, exercise, obesity experts, media, decision-makers) as well as a media analysis. The project involved active participation in discussions regarding obesity stigma in the media and different networks. The stigma of obesity, specially weight-related discrimination, has an impact on all main areas of life in our society. The existing practices, structures and processes focus on weight and not wellbeing, and the way we talk about obesity further worsens the stigma. To be able to move towards ethical and responsible weight dialogue and practices and to reduce the impact of obesity stigma, we need to gain more information and understanding of this stigma through education, research and value training. We need to improve obesityrelated communications and create ethical guidelines for obesity communication and illustration. A ban on discrimination based on size or weight should be included in the Nondiscrimination Act. nonPeerReviewed
Published: 2023

12. Cross-national time trends in adolescent body weight perception and the explanatory role of overweight/obesity prevalence

Author: Geraets, Anouk Francine Jacqueline, Cosma, Alina, Fismen, Anne-Siri, Ojala, Kristiina, Pierannunzio, Daniela, Kelly, Colette, Melkumova, Marina, Vassallo, Charlene, Gudelj Rakic, Jelena, and Heinz, Andreas
Subjects: trends, obesity, teini-ikäiset, weight perception, Pédiatrie [D19] [Sciences de la santé humaine], body weight congruence, Pediatrics [D19] [Human health sciences], asenteet, ylipaino, trendit, sukupuoli, nuoret, terveyskäyttäytyminen, kokemukset, overweight, lihavuus, adolescents
Abstract: Introduction Body weight perception (BWP) is associated with health behaviors. Current evidence points to an increase over time in both actual and perceived weight status among adolescents, however there is limited evidence on time trends in BWP in cross-national samples of adolescents. Therefore, the aims of this study were to examine time trends in BWP between 2002 and 2018 among adolescents from 41 countries and regions, including gender and country differences and to explore the role of changes over time in country-level overweight/obesity prevalence in these trends. Methods Data were used from five cycles (2002, 2006, 2010, 2014, 2018) of the repeated cross-sectional Health Behavior in School-Aged Children (HBSC) study (n = 746,121; mean±standard deviation age 13.7 ± 1.6 years, 51.0% girls). Multilevel logistic models estimated cross-national linear time trends in adolescent BWP (correct perception, underestimation, or overestimation), adjusted for gender, age, and family affluence. Next, we tested whether country-level changes over time overweight/obesity prevalence could explain these trends in BWP among adolescents. Results Correct weight perception increased over time among girls, while it decreased among boys. Underestimation of weight status increased, and overestimation of weight status decreased over time among both genders, with stronger trends for girls. Furthermore, country differences in trends in both BWP and overweight/obesity were found. Changes over time in country-level overweight/obesity prevalence could not explain these trends. Conclusion The linear increase over time in correct weight perception and the decrease in overestimation may have a positive effect on unhealthy weight reduction behaviors among adolescents. However, the increase in underestimation could signal a need for interventions to strengthen correct weight perception among adolescents. Several implications for policy and practice are discussed. peerReviewed
Published: 2023

13. Developing the 'Choosing Health' Digital Weight Loss and Maintenance Intervention: Intervention Mapping Study

Author: Iga Palacz-Poborczyk, Paulina Idziak, Anna Januszewicz, Aleksandra Luszczynska, Eleanor Quested, Felix Naughton, Martin S Hagger, Sherry Pagoto, Peter Verboon, Suzanne Robinson, Dominika Kwasnicka, RS-Research Program Understanding Human Change in a Dynamic, Digital Era (UHC), RS-Research Line Methodology & statistics (part of UHC program), and Section Methodology & Statistics
Subjects: behavior change, obesity, Obesity/therapy, behavior maintenance, digital health, Health Informatics, Health Promotion, Weight Gain, Health Promotion/methods, terveyden edistäminen, painonhallinta, käyttäytymismallit, Weight Loss, overweight, Humans, within-person design, Obesity, teleterveydenhuolto, Exercise, interventio, behavioral theory, intervention Mapping, laihdutus, ylipaino, interventiotutkimus, Overweight, satunnaistetut vertailukokeet, terveyskäyttäytyminen, randomized controlled trial, lihavuus, weight loss
Abstract: Background Digital health promotion programs tailored to the individual are a potential cost-effective and scalable solution to enable self-management and provide support to people with excess body weight. However, solutions that are widely accessible, personalized, and theory- and evidence-based are still limited. Objective This study aimed to develop a digital behavior change program, Choosing Health, that could identify modifiable predictors of weight loss and maintenance for each individual and use these to provide tailored support. Methods We applied an Intervention Mapping protocol to design the program. This systematic approach to develop theory- and evidence-based health promotion programs consisted of 6 steps: development of a logic model of the problem, a model of change, intervention design and intervention production, the implementation plan, and the evaluation plan. The decisions made during the Intervention Mapping process were guided by theory, existing evidence, and our own research—including 4 focus groups (n=40), expert consultations (n=12), and interviews (n=11). The stakeholders included researchers, public representatives (including individuals with overweight and obesity), and experts from a variety of relevant backgrounds (including nutrition, physical activity, and the health care sector). Results Following a structured process, we developed a tailored intervention that has the potential to reduce excess body weight and support behavior changes in people with overweight and obesity. The Choosing Health intervention consists of tailored, personalized text messages and email support that correspond with theoretical domains potentially predictive of weight outcomes for each participant. The intervention content includes behavior change techniques to support motivation maintenance, self-regulation, habit formation, environmental restructuring, social support, and addressing physical and psychological resources. Conclusions The use of an Intervention Mapping protocol enabled the systematic development of the Choosing Health intervention and guided the implementation and evaluation of the program. Through the involvement of different stakeholders, including representatives of the general public, we were able to map out program facilitators and barriers while increasing the ecological validity of the program to ensure that we build an intervention that is useful, user-friendly, and informative. We also summarized the lessons learned for the Choosing Health intervention development and for other health promotion programs. International Registered Report Identifier (IRRID) RR2-10.1136/bmjopen-2020-040183
Published: 2022
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14. Sleep-time physiological recovery is associated with eating habits in distressed working-age Finns with overweight: secondary analysis of a randomised controlled trial

Author: Järvelä-Reijonen, Elina, Järvinen, Suvi, Karhunen, Leila, Föhr, Tiina, Myllymäki, Tero, Sairanen, Essi, Lindroos, Sanni, Peuhkuri, Katri, Hallikainen, Maarit, Pihlajamäki, Jussi, Puttonen, Sampsa, Korpela, Riitta, Ermes, Miikka, Lappalainen, Raimo, Kujala, Urho M., Kolehmainen, Marjukka, Laitinen, Jaana, Department of Pharmacology, University of Helsinki, University Management, Riitta Anneli Korpela / Principal Investigator, and HUMI - Human Microbiome Research
Subjects: INDICATORS, WORKDAYS, elintavat, syke, palautuminen, Intuitive eating, Dietary behaviour, työikäiset, ruokavaliot, Stress, uni (lepotila), painonhallinta, tunteet, fysiologinen psykologia, syöminen, Heart rate variability, HEART-RATE-VARIABILITY, Parasympathetic activity, Research, laatu, ylipaino, Public Health, Global Health, Social Medicine and Epidemiology, MEN, stressi, Industrial medicine. Industrial hygiene, 3142 Public health care science, environmental and occupational health, ruokatottumukset, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, RC963-969, ravintokuitu, FISH CONSUMPTION, HEALTH, alkoholinkäyttö, BEHAVIOR
Abstract: Background Association of physiological recovery with nutrition has scarcely been studied. We investigated whether physiological recovery during sleep relates to eating habits, i.e., eating behaviour and diet quality. Methods Cross-sectional baseline analysis of psychologically distressed adults with overweight (N = 252) participating in a lifestyle intervention study in three Finnish cities. Recovery measures were based on sleep-time heart rate variability (HRV) measured for 3 consecutive nights. Measures derived from HRV were 1) RMSSD (Root Mean Square of the Successive Differences) indicating the parasympathetic activation of the autonomic nervous system and 2) Stress Balance (SB) indicating the temporal ratio of recovery to stress. Eating behaviour was measured with questionnaires (Intuitive Eating Scale, Three-Factor Eating Questionnaire, Health and Taste Attitude Scales, ecSatter Inventory™). Diet quality was quantified using questionnaires (Index of Diet Quality, Alcohol Use Disorders Identification Test Consumption) and 48-h dietary recall. Results Participants with best RMSSD reported less intuitive eating (p = 0.019) and less eating for physical rather than emotional reasons (p = 0.010) compared to those with poorest RMSSD; participants with good SB reported less unconditional permission to eat (p = 0.008), higher fibre intake (p = 0.028), higher diet quality (p = 0.001), and lower alcohol consumption (p
Published: 2021

15. The Added Value of Remote Technology in Cardiac Rehabilitation on Physical Function, Anthropometrics, and Quality of Life: Cluster Randomized Controlled Trial

Author: Heli Lahtio, Ari Heinonen, Teemu Paajanen, and Tuulikki Sjögren
Subjects: obesity, QoL, mobile phone, 6-minute walk test, laihdutus, fyysinen toimintakyky, ylipaino, Health Informatics, elämänlaatu, waist circumference, body mass, cardiac rehabilitation, BMI, physical function, quality of life, remote technology, sydän- ja verisuonitaudit, overweight, kuntoutus, weight loss, teleterveydenhuolto
Abstract: Background Cardiovascular diseases (CVDs) cause most deaths globally and can reduce quality of life (QoL) of rehabilitees with cardiac disease. The risk factors of CVDs are physical inactivity and increased BMI. With physical activity, it is possible to prevent CVDs, improve QoL, and help maintain a healthy body mass. Current literature shows the possibilities of digitalization and advanced technology in supporting independent self-rehabilitation. However, the interpretation of the results is complicated owing to the studies’ high heterogeneity. In addition, the added value of this technology has not been studied well, especially in cardiac rehabilitation. Objective We aimed to examine the effectiveness of added remote technology in cardiac rehabilitation on physical function, anthropometrics, and QoL in rehabilitees with CVD compared with conventional rehabilitation. Methods Rehabilitees were cluster randomized into 3 remote technology intervention groups (n=29) and 3 reference groups (n=30). The reference group received conventional cardiac rehabilitation, and the remote technology intervention group received conventional cardiac rehabilitation with added remote technology, namely, the Movendos mCoach app and Fitbit charge accelerometer. The 12 months of rehabilitation consisted of three 5-day in-rehabilitation periods in the rehabilitation center. Between these periods were two 6-month self-rehabilitation periods. Outcome measurements included the 6-minute walk test, body mass, BMI, waist circumference, and World Health Organization QoL-BREF questionnaire at baseline and at 6 and 12 months. Between-group differences were assessed using 2-tailed t tests and Mann-Whitney U test. Within-group differences were analyzed using a paired samples t test or Wilcoxon signed-rank test. Results Overall, 59 rehabilitees aged 41 to 66 years (mean age 60, SD 6 years; n=48, 81% men) were included in the study. Decrement in waist circumference (6 months: 1.6 cm; P=.04; 12 months: 3 cm; P Conclusions Remote cardiac rehabilitation added value to conventional cardiac rehabilitation in terms of waist circumference and QoL. The results were clinically small, but the findings suggest that adding remote technology to cardiac rehabilitation may increase beneficial health outcomes. There was some level of systematic error during rehabilitation intervention, and the sample size was relatively small. Therefore, care must be taken when generalizing the study results beyond the target population. To confirm assumptions of the added value of remote technology in rehabilitation interventions, more studies involving different rehabilitees with cardiac disease are required. Trial Registration ISRCTN Registry ISRCTN61225589; https://www.isrctn.com/ISRCTN61225589
Published: 2023
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16. Asuinympäristö vaikuttaa lapsen painon kehitykseen syntymästä kouluikään

Author: Lagström, Hanna
Subjects: kouluikäiset, kehon painon kehitys, lihavuus, asuinympäristö, ylipaino, Artikkelit
Abstract: Tuore Varsinais-Suomen alueella tehty tutkimus osoitti, että asuminen huono-osaisella asuinalueella on merkittävä riskitekijä epäsuotuisalle painon kehitykselle alle kouluikäisillä lapsilla.
Published: 2022

17. Food consumption trends among 48 to 57 years old women in Kuopio, Finland: 25 years follow-up OSTPRE study

Author: Thakur, Saima, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kansanterveystiede ja kliininen ravitsemustiede, Faculty of Health Sciences, School of Medicine, Public Health and Clinical Nutrition, Terveystieteiden tiedekunta, and Faculty of Health Sciences
Subjects: naiset, food, elintarvikkeet, ylipaino, livsmedel, kulutus, ruoka, mat, foodstuffs, ravitsemustiede, overweight, nutrition science, women, consumption, övervikt, konsumtion, kvinnor
Published: 2022

18. Energian ja energiaravintoaineiden saannin yhteys plasman ALAT-pitoisuuteen ylipainoisilla 7–12-vuotiailla lapsilla

Author: Peltoniemi, Anni, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kansanterveystiede ja kliininen ravitsemustiede, Faculty of Health Sciences, School of Medicine, Public Health and Clinical Nutrition, Terveystieteiden tiedekunta, and Faculty of Health Sciences
Subjects: science of nutrition, energia, obesity, children (age groups), rasvamaksa, non-alcoholic fatty liver disease, ylipaino, lapset (ikäryhmät), ruokavaliot, energi, ei-alkoholiperäinen rasvamaksasairaus, diets, fettlever, ravitsemustiede, lihavuus, overweight, näringslära, dieter, nutrition science, övervikt, fetma, icke alkoholbetingad fettlever, barn (åldersgrupper), fatty liver, energy
Published: 2022

19. Associations of overweight and metabolic health with successful aging: 32-year follow-up of the Helsinki Businessmen Study

Author: Arto Y. Strandberg, Veikko Salomaa, Timo E. Strandberg, Annele Urtamo, Mika Kivimäki, Mikaela B. von Bonsdorff, Satu K. Jyväkorpi, Kari Luotola, Clinicum, University of Helsinki, Helsinki University Hospital Area, HUS Heart and Lung Center, HUS Gynecology and Obstetrics, Department of Medicine, HUS Internal Medicine and Rehabilitation, and Timo Strandberg / Principal Investigator
Subjects: Male, 0301 basic medicine, Aging, FITNESS, IMPACT, RAND-36, Successful aging, Metabolically healthy overweight and obesity, elämänlaatu, Overweight, Critical Care and Intensive Care Medicine, OLD-AGE, 0302 clinical medicine, Quality of life, QUALITY-OF-LIFE, aineenvaihdunta, Finland, RISK, Nutrition and Dietetics, Hazard ratio, ylipaino, Middle Aged, 3. Good health, CARDIOVASCULAR-DISEASE, OBESITY, 3143 Nutrition, medicine.symptom, medicine.medical_specialty, 030209 endocrinology & metabolism, 03 medical and health sciences, Internal medicine, medicine, Humans, Aged, 030109 nutrition & dietetics, Metabolically unhealthy overweight and obesity, business.industry, MORTALITY, Odds ratio, medicine.disease, Obesity, Confidence interval, BODY-MASS INDEX, ikääntyminen, PHYSICAL-ACTIVITY, Nonagenarians, business, Body mass index, Follow-Up Studies
Abstract: Background & aims: Prognostic significance of metabolically healthy overweight and obesity (MHO) is under debate. However the relationship between MHO and health-related quality of life (HRQoL) is less studied. We compared successful aging (longevity plus HRQoL) in men with MHO, metabolically healthy normal weight (MHN) and metabolically unhealthy overweight and obesity (MUO). Methods: In the Helsinki Businessmen Study longitudinal cohort, consisting of men born 1919 to 1934. In 1985/86, overweight (BMI >= 25 kg/m(2)) and metabolic health were determined in 1309 men (median age 60 years). HRQoL was assessed using RAND-36/SF-36 in 2000 and 2007, and all-cause mortality retrieved from registers up to 2018. The proportion of men reaching 90 years was also calculated. Results: Of the men, 469 (35.8%), 538 (41.1%), 276 (21.1%), and 26 (2.0%) were MHN, MHO, MUO and MUN, respectively. During the 32-year follow-up, 72.3% men died. With MHN as reference, adjusted hazard ratio with all-cause mortality was 1.08 (95% confidence interval [CI] 0.93 to 1.27) for MHO, and 1.18 (95% CI 0.95 to 1.47) for MUO. During follow-up, 273 men reached 90 years. With MHN as reference, adjusted odds ratio for MHO was 0.82 (95% CI 0.59 to 1.14) and 0.62 (95% CI 0.41 to 0.95) for MUO. Men in MHN group scored generally highest in RAND-36 HRQoL subscales in 2000 and 2007, of those significantly better in Physical functioning, Role physical, Role emotional, Bodily Pain, and General health sub-scales compared to MHO group in 2000. Conclusions: As compared to MHN, MHO in late midlife does not increase mortality, but impairs odds for successful aging. (C) 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Published: 2020
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20. Rasvamaksaa vastaan rasittavalla liikunnalla

Author: Haapala, Eero
Subjects: nuoret, rasvamaksa, ennaltaehkäisy, ylipaino, liikunta, insuliiniresistenssi, metabolinen oireyhtymä, fyysinen aktiivisuus, fyysinen kuormittavuus
Abstract: nonPeerReviewed
Published: 2022

21. Lasten paino ei putoa ruutuaikaa vähentämällä

Author: Haapala, Eero
Subjects: meta-analyysi, ruutuaika, lapset (ikäryhmät), ylipaino, painoindeksi, fyysinen aktiivisuus
Abstract: nonPeerReviewed
Published: 2022

22. Suolistomikrobiston yhteys kardiometabolisten sairauksien riskitekijöihin ylipainoisilla tutkittavilla

Author: Hellsten, Ella
Subjects: suolisto, suolistomikrobisto, kardiometaboliset riskitekijät, lihavuus, ylipaino
Abstract: Tässä pro gradu -tutkielmassa selvitettiin suolistomikrobiston koostumuksen yhteyksiä kardiometabolisten sairauksien riskitekijöihin ylipainoisilla naisilla. Myös kuuden viikon kestävyysharjoittelun vaikutuksia tarkasteltiin tutkittavien suolistomikrobiston koostumukseen ja kardiometabolisiin riskitekijöihin. Lopuksi tarkasteltiin vielä muuttujien muutosten välisiä yhteyksiä. Tässä työssä on käytetty Munukan ym. (2018) tutkimuksen aineistoa. Tutkimukseen osallistui 15 ylipainoista keskimäärin 36,8-vuotiasta naista, jotka olivat sedentaarisia ja BMI oli yli 27,5 (kg/m²). Mittaukset suoritettiin perustasolla sekä kontrollijakson ja harjoitusjakson jälkeen. Mittaukset sisälsivät laboratoriotestejä sekä submaksimaalisen polkupyöräergometritestin. Näiden lisäksi tutkittavat täyttivät ruoka- ja liikuntapäiväkirjaa ja heidän tuli ylläpitää normaalia syömis- ja liikuntakäyttäytymistään koko tutkimuksen ajan. Kehonkoostumusta arvioitiin DXA-laitteella ja verinäytteistä analysoitiin eri rasva-arvoja, insuliini- ja glukoosiarvoja sekä tulehdustekijöitä. Tutkittavat keräsivät itseltään ulostenäytteet ohjeiden mukaisesti. Näytteistä eristettiin DNA ja suolistomikrobien koostumus analysoitiin 16S rRNA-geenin amplikonisekvensoinnin avulla. Liikunnan vaikutuksia suolistomikrobistoon tarkasteltiin tarkemmin metagenomianalyysillä. Tutkimuksen tilastollisia analyysejä tehtiin IBM SPSS Statistics 28-ohjelmalla (IBM, USA). Yhteyksiä tarkasteltiin Spearmanin korrelaatiotesteillä ja kardiometabolisten muuttujien keskiarvoeroja ennen ja jälkeen harjoitusjakson määritettiin kahden riippuvan otoksen t-testin avulla. Tutkittavien suolistomikrobien ja kehonkoostumuksen, rasva- ja kolesteroliarvojen, insuliiniresistenssin tason sekä elimistön tulehdusstatuksen välillä havaittiin monia yhteyksiä. Kestävyysharjoittelu laski tutkittavien painoa, keskivartalon rasvamassaa sekä LDLkolesterolia. Kestävyysharjoittelulla oli myös suolistomikrobiston koostumukseen vaikutuksia ja harjoittelun havaittiin lisäävän Verrucomicrobia-pääjakson, Verrucomicrobiaceae- ja Akkermansia-suvun sekä laskevan Proteobacteria-suvun suolistomikrobien määrää (Munukka ym. 2018). Muuttujien muutosten välillä havaittiin myös muutamia merkitseviä yhteyksiä. Johtopäätöksenä voidaan todeta, että suolistomikrobisto on yhteydessä kardiometabolisiin riskitekijöihin ylipainoisilla naisilla ja liikunnalla voidaan vaikuttaa myönteisesti kardiometabolisiin riskitekijöihin sekä suolistomikrobiston koostumukseen. Lisää tutkimusta kuitenkin tarvitaan suuremmalla aineistolla, jotta tuloksia voidaan yleistää ja pitää luotettavina.
Published: 2022

23. Standing time and daily proportion of sedentary time are associated with pain-related disability in a one month accelerometer measurement in adults with overweight or obesity

Author: Norha, Jooa, Hautala, Arto J., Sjöros, Tanja, Laine, Saara, Garthwaite, Taru, Knuuti, Juhani, Löyttyniemi, Eliisa, Vähä-Ypyä, Henri, Sievänen, Harri, Vasankari, Tommi, and Heinonen, Ilkka H. A.
Subjects: functional performance, accelerometry, lihavuus, kipu, overweight, sedentary behavior (SB), liikuntarajoitteet, ylipaino, pain, askelmittarit, fyysinen aktiivisuus
Abstract: Objectives: The association between the subjective experience of pain-related disability (PRD) and device-measured physical activity (PA) and sedentary behavior (SB) in overweight and obese adults is not well known. The aim of this study was to investigate the associations of pain markers with accelerometer-measured SB duration and different intensities of PA among physically inactive middle-aged adults with overweight or obesity. Methods: This cross-sectional analysis included 72 subjects (27 men) with mean age of 57.9 (SD 6.7) years and mean BMI of 31.6 (SD 4.1) kg/m². SB and standing time (ST), breaks in sedentary time, light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA) were measured for four consecutive weeks (mean 25 days, SD 4) with a hip-worn triaxial accelerometer. Headache, musculoskeletal pain, back pain, and PRD were assessed by visual analog scales (VAS) and using the Oswestry disability index (ODI). RAND-36 questionnaire was applied to assess health-related quality of life. The associations were studied by linear models. Results: ST was positively and SB proportion was negatively associated with PRD when adjusted for age, sex, BMI, accelerometry duration, MVPA, pain medication use, and general health perceptions assessed by RAND-36. No associations were found between ST and back pain. SB or different PA intensities were not associated with pain experience at specific sites. Conclusions: Longer daily ST, but not LPA or MVPA is associated with higher level of PRD. Correspondingly, higher proportion of SB is associated with lower level of PRD. This suggests that individuals with PRD prefer to stand, possibly to cope with pain. These results may highlight the importance of habitual standing behaviors in coping with experienced PRD in adults with overweight or obesity.
Published: 2022

24. Ylipaino ja elämäntilanteen vaikeudet selittävät Move!-tuloksia

Author: Joensuu, Laura
Subjects: rasvaprosentti, fyysinen toimintakyky, koululaiset, ylipaino, kuntotestit, liikunta, murrosikä, koettu terveys, elämäntilanne, fyysinen kunto, koululiikunta, Move!, arviointi, fyysinen aktiivisuus
Abstract: Liikunnanopetukseen integroitu Move!-fyysisen toimintakyvyn seurantajärjestelmä on kehitetty lasten ja nuorten fyysisen toimintakyvyn tukemiseen. Heikkojen Move!-tulosten taustalla on nuoren kokonaisvaltainen elämäntilanne, mutta erityisesti liiallisen rasvamassan kertyminen murrosiän aikana. Hyvät tulokset saaneet nuoret kokivat myös terveytensä hyväksi. nonPeerReviewed
Published: 2022

25. Reipas liikkuminen nuoruudessa ehkäisee ylipainoa

Author: Haapala, Eero
Subjects: rasva-aineenvaihdunta, nuoret, lihavuus, lapset (ikäryhmät), ennaltaehkäisy, ylipaino, liikunta, metabolinen oireyhtymä, kehonkoostumus
Abstract: nonPeerReviewed
Published: 2022

26. Rivakka liike ja kymmenen tunnin syömäaika vuorokaudessa laskee diabetesriskiä

Author: Haapala, Eero
Subjects: aineenvaihduntahäiriöt, diabetes, lihavuus, ylipaino, ennaltaehkäisy, liikunta, ruokavaliot, intervalliharjoittelu, paasto
Abstract: nonPeerReviewed
Published: 2022

27. Association between cardiorespiratory fitness and metabolic health in overweight and obese adults

Author: Haapala, Eero A., Sjöros, Tanja, Laine, Saara, Garthwaite, Taru, Kallio, Petri, Saarenhovi, Maria, Vähä-Ypyä, Henri, Löyttyniemi, Eliisa, Sievänen, Harri, Houttu, Noora, Laitinen, Kirsi, Kalliokoski, Kari, Knuuti, Juhani, Vasankari, Tommi, and Heinonen, Ilkka H. A.
Subjects: aerobic fitness, fyysinen kunto, insulin resistance, allometry, lihavuus, aerobinen suorituskyky, ylipaino, insuliiniresistenssi, metabolinen oireyhtymä, metabolic syndrome
Abstract: BACKGROUND: Cardiorespiratory fitness (CRF) has been inversely associated with insulin resistance and clustering of cardiometabolic risk factors among overweight and obese individuals. However, most previous studies have scaled CRF by body mass (BM) possibly inflating the association between CRF and cardiometabolic health. We investigated the associations of peak oxygen uptake (V̇ O2peak) and peak power output (Wpeak) scaled either by BM-1, fat free mass (FFM-1), or by allometric methods with individual cardiometabolic risk factors and clustering of cardiometabolic risk factors in 55 overweight or obese adults with metabolic syndrome. METHODS: V̇ O2peak and Wpeak were assessed by a maximal cycle ergometer exercise test. FFM was measured by air displacement plethysmograph and glucose, insulin, HbA1c, triglycerides, and total, LDL, and HDL cholesterol from fasting blood samples. HOMA-IR and metabolic syndrome score (MetS) were computed. RESULTS: V̇ O2peak and Wpeak scaled by BM-1 were inversely associated with insulin (β=-0.404 to -0.372, 95% CI=-0.704 to -0.048), HOMA-IR (β=-0.442 to -0.440, 95% CI=-0.762 to -0.117), and MetS (β=-0.474 to -0.463, 95% CI’s=-0.798 to -0.127). Other measures of CRF were not associated with cardiometabolic risk factors. CONCLUSIONS: Our results suggest that using BM-1 as a scaling factor confounds the associations between CRF and cardiometabolic risk in overweight/obese adults with the metabolic syndrome. peerReviewed
Published: 2022

28. The Effectiveness of Physical Activity-Promoting Web- and Mobile-Based Distance Weight Loss Interventions on Body Composition in Rehabilitation Settings : Systematic Review, Meta-analysis, and Meta-Regression Analysis

Author: Lahtio, Heli, Rintala, Aki, Immonen, Jaakko, and Sjögren, Tuulikki
Subjects: obesity, mobile phone, rasvaprosentti, laihdutus, body mass index, ylipaino, liikunta, waist circumference, body fat percentage, rehabilitation, terveyden edistäminen, painonhallinta, mobiilipalvelut, technology, terveysvaikutukset, teknologia, overweight, lihavuus, kuntoutus, weight loss, maailmanlaajuiset ongelmat, painoindeksi, fyysinen aktiivisuus, verkkopalvelut
Abstract: Background: Overweight and obesity are major problems worldwide, and they lead to an increased risk for several diseases. The use of technology in the treatment of obesity is promising, but in the existing literature, there is considerable uncertainty regarding its efficacy. In this review, we included web- and mobile-based weight loss interventions that were implemented remotely in rehabilitation settings. Objective: The aim of this systematic review is to study the effectiveness of physical activity-promoting web- and mobile-based distance weight loss interventions in rehabilitation settings on body composition in comparison with control groups that did not use technology. Methods: Studies were searched from 9 databases. The inclusion criteria were as follows: population: age 18-65 years; intervention: physical activity-promoting web- and mobile-based distance weight loss interventions; comparison: control groups without the use of technology; outcome: changes in BMI, waist circumference, or body fat percentage; study design: randomized controlled trial. The quality of the studies was assessed by 2 researchers. Meta-analysis was performed, and we also conducted a meta-regression analysis to evaluate the factors associated with the changes in body composition outcomes if statistical heterogeneity was observed. Results: The meta-analysis included 30 studies. The mean quality of the studies was 7 of 13 (SD 1.9; range 3-10). A statistically significant difference was observed in BMI (mean difference [MD] 0.83, 95% CI 0.51-1.15 kg/m2; P
Published: 2022

29. Kestävyyskuntoa vai normaalipainoa sydäntautien ehkäisyyn?

Author: Haapala, Eero
Subjects: kuolleisuus, fyysinen kunto, sydän- ja verisuonitaudit, lihavuus, ylipaino
Abstract: nonPeerReviewed
Published: 2022

30. Motorisen taitavuuden kynnysteorialle tukea ylipainoisuuden osalta

Author: Laukkanen, Arto
Subjects: liikuntataidot, ylipaino, lapset (ikäryhmät), liikuntaharrastus, motoriset taidot, fyysinen aktiivisuus
Abstract: nonPeerReviewed
Published: 2022

31. Associations of muscular fitness and body composition in children

Author: Marjo Rinne, Pauli Rintala, Katriina Kukkonen-Harjula, Juha Valtonen, Sari Slotte, Department of Education, HYKS erva, Helsinki University Hospital Area, and Kasvatus, opetus ja opettajankoulutus
Subjects: Test battery, obesity, Social Psychology, Physical activity, CHILDHOOD, Physiology, 030209 endocrinology & metabolism, lapset (ikäryhmät), ADULTHOOD, Overweight, Pediatrics, DEFINITIONS, 03 medical and health sciences, TRACKING, 0302 clinical medicine, STRENGTH, Developmental and Educational Psychology, Abdominal fat, medicine, overweight, kehonkoostumus, Adiposity, DXA, adiposity, Total body, ylipaino, 030229 sport sciences, medicine.disease, Obesity, fyysinen kunto, PHYSICAL-ACTIVITY, YOUTH, health-related fitness, lihavuus, 516 Educational sciences, medicine.symptom, Psychology, lihaskunto
Abstract: Purpose: To examine the associations between muscular fitness (MF) and body composition. Method: MF was assessed with three tests of FitnessGram test battery. Total body fat percentage (BF%), abdominal fat percentage (AF%) and fat-free mass (FFM) were measured by dual-energy X-ray absorptiometry (DXA). The IOTF body mass index (BMI) cut-offs were used to define healthy weight, overweight, and obesity. Results: MF was inversely associated with BF% and AF%. The children in the moderate and high MF groups had significantly lower BF% and AF% compared with the children in the low MF group within the same BMI category. After adjusting for cardiorespiratory fitness (CRF), BMI and sex, the differences between the MF groups were significant for BF% but not for AF%. Conclusion: There were significant inverse associations between MF and DXA -measured adiposity. Within the same BMI category, total and abdominal adiposity were lower in children with moderate or high MF than in children with low MF.
Published: 2022

32. Microbiota of the first stool after birth

Author: Kielenniva, K. (Katja), Tapiainen, T. (Terhi), Pirttilä, A. (Anna Maria), and Renko, M. (Marjo)
Subjects: intestinal microbiota, atopia, mekonium, growth, suolistomikrobisto, atopic eczema, meconium, overweight, ylipaino, imeväisen koliikki, first-pass meconium, kasvu, infantile colic
Abstract: Meconium, a newborns’ first stool after birth, is the first easily available sample for gut microbiota studies. Recent studies have shown that first-pass meconium contains bacteria and that factors such as gestational age and delivery mode can impact meconium microbiota composition. The purpose of this thesis was to investigate what factors affect the bacterial composition of first-pass meconium and the impact of meconium microbiota on later health. This was a prospective cohort study of 212 consecutive newborns. The first stool after birth was collected and analyzed using next-generation sequencing of the bacterial 16S rRNA gene. Fecal samples were also collected at one year of age. Clinical follow ups were conducted until the participants reached four years of age. In total, 91% of the first-pass meconium samples contained bacterial DNA. The composition of first-pass meconium was distinct from that of the gut microbiota at one year of age. The biodiversity of the maternal living environment during pregnancy was associated with the bacterial composition of the first stool. The bacterial composition of first-pass meconium was associated with the subsequent health of the infants. The infants with infantile colic had less lactobacilli in their meconium microbiota than those without colic. The children who were overweight at three years of age had less phylum Bacteroidetes and genus Bacteroides in their first-pass meconium than children with normal weight. The composition of intestinal microbiota at 1 year of age was not associated with the risk of being overweight in early childhood. The bacterial composition of meconium microbiota was not associated with subsequent atopic eczema or wheezing. This thesis shows that earlier reported associations between intestinal microbiota, infantile colic, and overweight appear to be present immediately after birth. These findings emphasize the importance of pre- and perinatal factors on the early intestinal colonization and later health of children. Tiivistelmä Elämän ensimmäisen uloste, mekonium, tarjoaa ensimmäisen helposti saatavilla olevan näytteen suolistomikrobiston tutkimiseen. Viimeaikaiset tutkimukset ovat osoittaneet, että mekonium sisältää bakteereita. Muun muassa raskauden keston ja synnytystavan on raportoitu vaikuttavan mekoniumin bakteerikoostumukseen. Tässä väitöskirjassa tutkittiin mekoniumin mikrobiston koostumukseen vaikuttavia tekijöitä sekä mekoniumin mikrobiston yhteyttä lapsen myöhempään terveyteen. Tutkimuksen aineistona on 212 täysiaikaisen lapsen kohortti. Ensimmäinen mekonium kerättiin ja sen bakteerikoostumus analysoitiin bakteerin 16S rRNA-geenin sekvensoinnin avulla. Lisäksi lapsilta kerättiin seurantaulostenäyte yhden vuoden iässä. Tutkimukseen osallistuneita lapsia seurattiin neljän vuoden ikään asti. Tutkimus osoitti, että 91 % mekonium-näytteistä sisälsi bakteerien DNA:ta. Mekoniumin mikrobiston koostumus poikkesi selkeästi suolistomikrobiston koostumuksesta yhden vuoden iässä. Raskauden ja syntymän aikaisista tekijöistä erityisesti äidin elinympäristön monimuotoisuus oli yhteydessä mekoniumin mikrobiston koostumukseen. Tutkimuksessa havaittiin, että mekoniumin bakteerikoostumus oli yhteydessä lasten myöhempiin terveysongelmiin. Lapsilla, jotka kärsivät imeväisen koliikista, oli vähemmän laktobasilleja jo mekoniumin mikrobistossa kuin niillä lapsilla, joilla ei ollut koliikkia. Niillä lapsilla, jotka olivat ylipainoisia kolmen vuoden iässä, oli enemmän Bacteroidetes -pääjakson sekä Bacteroides -suvun bakteereita mekoniumissa kuin normaalipainoisilla lapsilla. Suolistomikrobiston koostumus yhden vuoden iässä ei ollut yhteydessä lapsen ylipainoon. Mekoniumin mikrobiston bakteerikoostumus ei ollut yhteydessä myöhempään atooppiseen ihottumaan tai hengityksen vinkumiseen. Tämä väitöskirja osoittaa, että vastasyntyneen mekoniumin mikrobiston koostumus on yhteydessä koliikkiin ja ylipainon kehittymiseen lapsuusiässä. Tämä korostaa raskauden ja synnytykseen liittyvien tekijöiden merkitystä suolistomikrobiston muodostumiselle sekä lapsen myöhemmälle terveydelle.
Published: 2021

33. Fyysisen aktiivisuuden yhteys palveluskelpoisuusluokkaan ja palveluksen keskeyttämiseen:väestöpohjainen kutsuntaikäisten MOPO-tutkimus

Author: Niskanen, M. (Miika), Paananen, V. (Valtteri), Nurkkala, M. (Marjukka), Mäntysaari, M. (Matti), Korpelainen, R. (Raija), Pyky, R. (Riitta), Niskanen, M. (Miika), Paananen, V. (Valtteri), Nurkkala, M. (Marjukka), Mäntysaari, M. (Matti), Korpelainen, R. (Raija), and Pyky, R. (Riitta)
Abstract: Tiivistelmä Varusmiesten kunto on heikentynyt voimakkaasti 1990-luvulta lähtien. Tämän tutkimuksen tarkoituksena oli selvittää varusmiespalvelusta edeltävän fyysisen aktiivisuuden yhteyttä palveluskelpoisuusluokkien määräytymiseen ja varusmiespalveluksen keskeyttämiseen. Tutkimus oli osa laajempaa MOPO-hanketta, jonka tavoitteena oli aktivoida nuoria miehiä liikkumaan ja ehkäistä heidän syrjäytymistään. Tutkimukseen kutsuttiin mukaan kaikki Oulun kaupungin kutsuntatilaisuuksiin vuosina 2012 ja 2013 osallistuneet miehet (n = 2547), joille määrättiin kutsunnoissa palveluskelpoisuusluokka. Kutsuntatilaisuudessa 1852 (72,7 prosenttia) miestä vastasi terveys- ja elintapakyselyyn. Heistä 1398 (75,5 prosenttia) vastasi kyselyn osioon, jolla kartoitettiin vapaa-ajan fyysistä aktiivisuutta. Vastausten perusteella miehet luokiteltiin fyysisesti aktiivisiin ja vähän liikkuviin. Fyysisesti aktiivisten todennäköisyys saada palveluskelpoisuusluokaksi A oli korkeampi kuin vähän liikkuvien (p < 0,001). Vähän liikkuvien todennäköisyys saada lykkäystä palvelukseen astumiseen tai vapautus rauhanaikaisesta palveluksesta oli suurempi kuin fyysisesti aktiivisten. Myös varusmiespalveluksen keskeyttämisen riski oli suurempi niillä kutsuntaikäisillä, jotka olivat ennen kutsuntoja liikkuneet vähän (OR 2,3; 95 % CI 1,4–3,9; p = 0,002) tai joiden painoindeksi oli korkea (OR 1,1; 95 % CI 1,0–1,2; p = 0,001). Palvelusta edeltävä säännöllinen liikkuminen voi edistää kutsuntaikäisten miesten palveluskelpoisuutta ja vähentää riskiä palveluksen keskeyttämiseen. Korkean painoindeksin ja keskeyttämisen yhteys vahvistaa aiempaa käsitystä nuorten miesten ylipainon ja lihavuuden vaikutuksesta varusmiespalveluksesta suoriutumiseen. Lihavuus ja vähäinen fyysinen aktiivisuus olisi tärkeää tunnistaa viimeistään kutsuntojen yhteydessä ja kohdentaa riskihenkilöille fyysistä aktiivisuutta edistäviä interventioita., The association between physical activity and fitness for military service classification and the interruption of military service : a population-based MOPO study In Finland, physical fitness of the conscripts has declined since the 1990s. The aim of this study was to investigate the associations between self-reported physical activity, fitness for military service classification and the risk for interrupted military service. This study is part of a comprehensive MOPO-project, the goal of which was to promote physical activity and prevent marginalisation among young men. A total of 2547 adolescent men attended compulsory call-ups for military service in 2012 and 2013 and 1852 (72.7%) completed a study questionnaire regarding health and lifestyle. Out of them, 1398 (75.5%) answered a question concerning leisure time physical activity. The subjects were classified into physically active and inactive groups. Physically active adolescent men were more likely to be classified into the military service class A compared to physically inactive men (p < 0.001). Low physical activity level was associated with increased probability of military service deferment and exemption from military service. Low physical activity (OR 2.3; 95% CI 1.4–3.9; p = 0.002) and high body mass index (BMI) (OR 1.1; 95% CI 1.0–1.2; p = 0.001) were associated with exemption from military service. Regular physical activity may improve conscripts’ suitability and fitness for military service and reduce the risk of exemption from military service. High BMI and risk of being exempted from military service highlights the previous perception of the negative effect of overweight for military services. Low physical activity and obesity should at the latest be taken into account at call-ups and target physical activity interventions for physically inactive and obese adolescent men.
Published: 2021

34. Microbiota of the first stool after birth

Author: Tapiainen, T. (Terhi), Pirttilä, A. (Anna Maria), Renko, M. (Marjo), Kielenniva, K. (Katja), Tapiainen, T. (Terhi), Pirttilä, A. (Anna Maria), Renko, M. (Marjo), and Kielenniva, K. (Katja)
Abstract: Meconium, a newborns’ first stool after birth, is the first easily available sample for gut microbiota studies. Recent studies have shown that first-pass meconium contains bacteria and that factors such as gestational age and delivery mode can impact meconium microbiota composition. The purpose of this thesis was to investigate what factors affect the bacterial composition of first-pass meconium and the impact of meconium microbiota on later health. This was a prospective cohort study of 212 consecutive newborns. The first stool after birth was collected and analyzed using next-generation sequencing of the bacterial 16S rRNA gene. Fecal samples were also collected at one year of age. Clinical follow ups were conducted until the participants reached four years of age. In total, 91% of the first-pass meconium samples contained bacterial DNA. The composition of first-pass meconium was distinct from that of the gut microbiota at one year of age. The biodiversity of the maternal living environment during pregnancy was associated with the bacterial composition of the first stool. The bacterial composition of first-pass meconium was associated with the subsequent health of the infants. The infants with infantile colic had less lactobacilli in their meconium microbiota than those without colic. The children who were overweight at three years of age had less phylum Bacteroidetes and genus Bacteroides in their first-pass meconium than children with normal weight. The composition of intestinal microbiota at 1 year of age was not associated with the risk of being overweight in early childhood. The bacterial composition of meconium microbiota was not associated with subsequent atopic eczema or wheezing. This thesis shows that earlier reported associations between intestinal microbiota, infantile colic, and overweight appear to be present immediately after birth. These findings emphasize the importance of pre- and perinatal factors on the early intestinal colonization an, Tiivistelmä Elämän ensimmäisen uloste, mekonium, tarjoaa ensimmäisen helposti saatavilla olevan näytteen suolistomikrobiston tutkimiseen. Viimeaikaiset tutkimukset ovat osoittaneet, että mekonium sisältää bakteereita. Muun muassa raskauden keston ja synnytystavan on raportoitu vaikuttavan mekoniumin bakteerikoostumukseen. Tässä väitöskirjassa tutkittiin mekoniumin mikrobiston koostumukseen vaikuttavia tekijöitä sekä mekoniumin mikrobiston yhteyttä lapsen myöhempään terveyteen. Tutkimuksen aineistona on 212 täysiaikaisen lapsen kohortti. Ensimmäinen mekonium kerättiin ja sen bakteerikoostumus analysoitiin bakteerin 16S rRNA-geenin sekvensoinnin avulla. Lisäksi lapsilta kerättiin seurantaulostenäyte yhden vuoden iässä. Tutkimukseen osallistuneita lapsia seurattiin neljän vuoden ikään asti. Tutkimus osoitti, että 91 % mekonium-näytteistä sisälsi bakteerien DNA:ta. Mekoniumin mikrobiston koostumus poikkesi selkeästi suolistomikrobiston koostumuksesta yhden vuoden iässä. Raskauden ja syntymän aikaisista tekijöistä erityisesti äidin elinympäristön monimuotoisuus oli yhteydessä mekoniumin mikrobiston koostumukseen. Tutkimuksessa havaittiin, että mekoniumin bakteerikoostumus oli yhteydessä lasten myöhempiin terveysongelmiin. Lapsilla, jotka kärsivät imeväisen koliikista, oli vähemmän laktobasilleja jo mekoniumin mikrobistossa kuin niillä lapsilla, joilla ei ollut koliikkia. Niillä lapsilla, jotka olivat ylipainoisia kolmen vuoden iässä, oli enemmän Bacteroidetes -pääjakson sekä Bacteroides -suvun bakteereita mekoniumissa kuin normaalipainoisilla lapsilla. Suolistomikrobiston koostumus yhden vuoden iässä ei ollut yhteydessä lapsen ylipainoon. Mekoniumin mikrobiston bakteerikoostumus ei ollut yhteydessä myöhempään atooppiseen ihottumaan tai hengityksen vinkumiseen. Tämä väitöskirja osoittaa, että vastasyntyneen mekoniumin mikrobiston koostumus on yhteydessä koliikkiin ja ylipainon kehittymiseen lapsuusiässä. Tämä korostaa raskauden ja synnytykseen liittyvien tekijöiden merkit
Published: 2021

35. Häiriintynyt syömiskäyttäytyminen, paino ja fyysinen aktiivisuus:nuoret miehet ja ylipainoiset työikäiset

Author: Korpelainen, R. (Raija), Vanhala, M. (Marja), Teeriniemi, A. (Anna-Maria), Nurkkala, M. (Marjukka), Korpelainen, R. (Raija), Vanhala, M. (Marja), Teeriniemi, A. (Anna-Maria), and Nurkkala, M. (Marjukka)
Abstract: Disordered eating behavior (DEB) is associated with psychological distress. It increases the risk of weight gain and complicates weight loss and maintenance. Disordered eating behavior may be under-recognized in young men and in treating obesity. This study aimed to increase knowledge of DEB and its associations with weight and physical activity in young men. Moreover, it aimed to clarify the effects of intensive lifestyle intervention on eating behavior traits and weight in adults. Population-based data on young men (n = 2,491) was collected from the Finnish Defence Forces’ call-ups in 2010, 2011, and 2013 in the Oulu area, Finland. Behaviors related to disordered eating, weight, and exercise were investigated using a questionnaire. Anthropometric and physical fitness measurements and medical examinations were performed. A second dataset was obtained from 120 working-age adults (BMI > 30) who participated in intensive lifestyle intervention. Questions related to eating behavior traits were asked at the beginning of the study and thrice during a three-year intervention. Heights and weights were measured. Disordered eating behavior occurred in 11.1% of young men and was more common among overweight men. General symptoms of DEB and compulsive desire to lose weight occurred more frequently in overweight young men, while bulimic behavior occurred with all weights. Four DEB profiles were recognized: compulsive thinking of dieting, eating in secret, being concerned about eating control, and mild disordered eating. Disordered eating behavior was associated with less physical activity, higher sedentary leisure time, and especially body-related motives to exercise. Among working-aged people, binge eating occurred in one in four women but was rare in men. During the intensive lifestyle intervention, impulsive eating decreased and emotional eating was lower at the end of the intervention among those who lost and maintained at least 5% of their weight. Cognitive restra, Tiivistelmä Häiriintynyt syömiskäyttäytyminen on yhteydessä psyykkiseen pahoinvointiin sekä altistaa painonnousulle ja vaikeuttaa laihtumista ja painonhallintaa. Nuorilla miehillä ja etenkin lihavuuden hoidossa syömishäiriöoireet voivat jäädä huomioimatta. Tämän väitöskirjatyön tavoitteena oli lisätä tietoa nuorten miesten häiriintyneestä syömiskäyttäytymisestä ja sen yhteydestä painoon ja liikuntakäyttäytymiseen. Tavoitteena oli myös selvittää tehostetun elintapaohjauksen vaikutusta työikäisten syömiskäyttäytymispiirteisiin ja painon muutokseen. Nuorten miesten väestöpohjainen aineisto (n = 2491) kerättiin Oulun alueen kutsunnoissa vuosina 2010, 2011 ja 2013. Miesten syömis-, paino- ja liikuntakäyttäytymistä kartoitettiin kyselyllä ja heille tehtiin antropometrian ja fyysisen kunnon mittaukset sekä terveystarkastus. Toinen aineisto koostui elintapaohjausinterventioon osallistuneista 120 työikäisestä (BMI > 30). Tutkittavat täyttivät tutkimuksen alussa ja kolmevuotisen intervention eri vaiheissa kyselyn, jolla selvitettiin heidän syömiskäyttäytymistään. Heidän pituutensa ja painonsa mitattiin. Häiriintynyttä syömiskäyttäytymistä esiintyi 11,1 prosentilla nuorista miehistä, ja se oli yleisempää ylipainoisilla. Yleisiä syömishäiriöoireita ja pakonomaista laihtumisen halua esiintyi enemmän ylipainoisilla, kun taas ahmimisen oireita esiintyi kaiken painoisilla. Tutkimuksessa tunnistettiin neljä syömishäiriöoireilun profiilia: laihtumista tavoittelevat, salaa ahmivat, syömisen hallinnastaan huolestuneet ja lievästi syömisellään oireilevat. Häiriintynyt syömiskäyttäytyminen oli yhteydessä vähäisempään fyysiseen aktiivisuuteen, runsaampaan istumiseen ja etenkin kehokeskeisiin liikkumismotiiveihin. Työikäisten aineistossa joka neljännellä naisella esiintyi ahmimista, miehillä ei juurikaan. Elintapaohjauksen myötä pysyvästi vähintään viisi prosenttia laihtuneilla impulsiivinen syöminen väheni ja tunnesyöminen oli intervention lopussa vähäisempää kuin heillä, joiden paino ei
Published: 2021

36. Shorter recovery time following high-intensity interval training induced higher body fat loss among overweight women

Subjects: naiset, overweight women, metabolic indices, palautuminen, laihdutus, HIIT, ta3141, ylipaino, interval recovery time, weight loss, ta315, intervalliharjoittelu, aineenvaihdunta
Published: 2019

37. Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Subjects: obesity, alueelliset erot, maaseutuväestö, lihavuus, overweight, risk factors, ylipaino, body mass index, ta3142, riskitekijät, rural population, painoindeksi, regional differences
Published: 2019

38. The effect of weight on labor market outcomes : An application of genetic instrumental variables

Subjects: sosiaaliturva, obesity, tulonsiirrot, ta511, ansiotulot, työllisyys, ylipaino, ta3142, genetiset tekijät, employment, overweight, lihavuus, genetics, social income transfers, earnings
Published: 2019
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39. Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

Author: Sievänen, Tero, Törmäkangas, Timo, Laakkonen, Eija K., Mecklin, Jukka-Pekka, Pylvänäinen, Kirsi, Seppälä, Toni T., Peltomäki, Päivi, Sipilä, Sarianna, Sillanpää, Elina, HUS Abdominal Center, Clinicum, Department of Surgery, Department of Medical and Clinical Genetics, University of Helsinki, and Institute for Molecular Medicine Finland
Subjects: elintavat, perinnölliset taudit, MENOPAUSE, lifestyle, MUTATIONS, 3122 Cancers, hereditary non-polyposis colorectal cancer, ylipaino, EXERCISE, suolistosyövät, riskitekijät, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Article, COLORECTAL-CANCER, ESTROGEN, ADIPOSE-TISSUE, MASS INDEX, AGE, DEFINED FAMILIAL RISK, epidemiology, epidemiologia, Lynchin oireyhtymä, fyysinen aktiivisuus, ASSOCIATIONS
Abstract: Simple Summary Lifestyle modifies cancer risk in the general public. How lifestyle modifies cancer risk in individuals carrying the inherited pathogenic gene variants in DNA mismatch repair genes (Lynch syndrome) remains understudied. We conducted a retrospective study with cancer register data to investigate associations between body weight, physical activity, and cancer risk among Finnish Lynch syndrome carriers (n = 465, 54% women). The results of our study indicated that longitudinal weight gain increases cancer risk, whereas being highly physically active during adulthood could decrease cancer risk in men. Further, women were observed to be less prone to lifestyle-related risk factors than men. The results emphasize the role of weight maintenance and high-intensity physical activity throughout the lifespan, especially in men with Lynch syndrome. Lynch syndrome (LS) increases cancer risk. There is considerable individual variation in LS cancer occurrence, which may be moderated by lifestyle factors, such as body weight and physical activity (PA). The potential associations of lifestyle and cancer risk in LS are understudied. We conducted a retrospective study with cancer register data to investigate associations between body weight, PA, and cancer risk among Finnish LS carriers. The participants (n = 465, 54% women) self-reported their adulthood body weight and PA at 10-year intervals. Overall cancer risk and colorectal cancer (CRC) risk was analyzed separately for men and women with respect to longitudinal and near-term changes in body weight and PA using extended Cox regression models. The longitudinal weight change was associated with an increased risk of all cancers (HR 1.02, 95% CI 1.00-1.04) and CRC (HR 1.03, 1.01-1.05) in men. The near-term weight change was associated with a lower CRC risk in women (HR 0.96, 0.92-0.99). Furthermore, 77.6% of the participants retained their PA category over time. Men in the high-activity group had a reduced longitudinal cancer risk of 63% (HR 0.37, 0.15-0.98) compared to men in the low-activity group. PA in adulthood was not associated with cancer risk among women. These results emphasize the role of weight maintenance and high-intensity PA throughout the lifespan in cancer prevention, particularly in men with LS.
Published: 2021

40. Ylipainoisten nuorten terveellisiin elintapoihin sitoutumisen ja sosiaalisen tuen yhteys fyysiseen aktiivisuuteen ja ruutuaikaan.

Author: NISKALA, JONNA, RUOTSALAINEN, HEIDI, KYNGÄS, HELVI, and KÄÄRIÄINEN, MARIA
Subjects: HEALTH behavior, CHILDHOOD obesity, QUESTIONNAIRES, SOCIAL support, LIFESTYLES, RANDOMIZED controlled trials, PHYSICAL activity
Published: 2015

41. Häiriintynyt syömiskäyttäytyminen, paino ja fyysinen aktiivisuus:nuoret miehet ja ylipainoiset työikäiset

Author: Nurkkala, M. (Marjukka), Korpelainen, R. (Raija), Vanhala, M. (Marja), and Teeriniemi, A. (Anna-Maria)
Subjects: esiintyvyys, adult, prevalence, laihdutus, cross-sectional studies, physical activity, ylipaino, disordered eating, eating behavior, työikäiset, syömiskäyttäytyminen, nuoret, adolescent, overweight, poikkileikkaustutkimukset, recognition, weight loss, syömishäiriöt, intervention, fyysinen aktiivisuus, interventio, tunnistaminen
Abstract: Disordered eating behavior (DEB) is associated with psychological distress. It increases the risk of weight gain and complicates weight loss and maintenance. Disordered eating behavior may be under-recognized in young men and in treating obesity. This study aimed to increase knowledge of DEB and its associations with weight and physical activity in young men. Moreover, it aimed to clarify the effects of intensive lifestyle intervention on eating behavior traits and weight in adults. Population-based data on young men (n = 2,491) was collected from the Finnish Defence Forces’ call-ups in 2010, 2011, and 2013 in the Oulu area, Finland. Behaviors related to disordered eating, weight, and exercise were investigated using a questionnaire. Anthropometric and physical fitness measurements and medical examinations were performed. A second dataset was obtained from 120 working-age adults (BMI > 30) who participated in intensive lifestyle intervention. Questions related to eating behavior traits were asked at the beginning of the study and thrice during a three-year intervention. Heights and weights were measured. Disordered eating behavior occurred in 11.1% of young men and was more common among overweight men. General symptoms of DEB and compulsive desire to lose weight occurred more frequently in overweight young men, while bulimic behavior occurred with all weights. Four DEB profiles were recognized: compulsive thinking of dieting, eating in secret, being concerned about eating control, and mild disordered eating. Disordered eating behavior was associated with less physical activity, higher sedentary leisure time, and especially body-related motives to exercise. Among working-aged people, binge eating occurred in one in four women but was rare in men. During the intensive lifestyle intervention, impulsive eating decreased and emotional eating was lower at the end of the intervention among those who lost and maintained at least 5% of their weight. Cognitive restraint of eating was not associated with maintaining weight loss. These results indicate that DEB is common among overweight young men. It is also associated with other harmful health behaviors in young men and should be considered harmful, especially in treating obesity. New methods are required to recognize DEB in men. Tiivistelmä Häiriintynyt syömiskäyttäytyminen on yhteydessä psyykkiseen pahoinvointiin sekä altistaa painonnousulle ja vaikeuttaa laihtumista ja painonhallintaa. Nuorilla miehillä ja etenkin lihavuuden hoidossa syömishäiriöoireet voivat jäädä huomioimatta. Tämän väitöskirjatyön tavoitteena oli lisätä tietoa nuorten miesten häiriintyneestä syömiskäyttäytymisestä ja sen yhteydestä painoon ja liikuntakäyttäytymiseen. Tavoitteena oli myös selvittää tehostetun elintapaohjauksen vaikutusta työikäisten syömiskäyttäytymispiirteisiin ja painon muutokseen. Nuorten miesten väestöpohjainen aineisto (n = 2491) kerättiin Oulun alueen kutsunnoissa vuosina 2010, 2011 ja 2013. Miesten syömis-, paino- ja liikuntakäyttäytymistä kartoitettiin kyselyllä ja heille tehtiin antropometrian ja fyysisen kunnon mittaukset sekä terveystarkastus. Toinen aineisto koostui elintapaohjausinterventioon osallistuneista 120 työikäisestä (BMI > 30). Tutkittavat täyttivät tutkimuksen alussa ja kolmevuotisen intervention eri vaiheissa kyselyn, jolla selvitettiin heidän syömiskäyttäytymistään. Heidän pituutensa ja painonsa mitattiin. Häiriintynyttä syömiskäyttäytymistä esiintyi 11,1 prosentilla nuorista miehistä, ja se oli yleisempää ylipainoisilla. Yleisiä syömishäiriöoireita ja pakonomaista laihtumisen halua esiintyi enemmän ylipainoisilla, kun taas ahmimisen oireita esiintyi kaiken painoisilla. Tutkimuksessa tunnistettiin neljä syömishäiriöoireilun profiilia: laihtumista tavoittelevat, salaa ahmivat, syömisen hallinnastaan huolestuneet ja lievästi syömisellään oireilevat. Häiriintynyt syömiskäyttäytyminen oli yhteydessä vähäisempään fyysiseen aktiivisuuteen, runsaampaan istumiseen ja etenkin kehokeskeisiin liikkumismotiiveihin. Työikäisten aineistossa joka neljännellä naisella esiintyi ahmimista, miehillä ei juurikaan. Elintapaohjauksen myötä pysyvästi vähintään viisi prosenttia laihtuneilla impulsiivinen syöminen väheni ja tunnesyöminen oli intervention lopussa vähäisempää kuin heillä, joiden paino ei laskenut pysyvästi. Syömisen tietoinen rajoittaminen ei ollut yhteydessä painonhallintaan. Tämä tutkimus osoitti, että syömishäiriöoireilu on yleisempää ylipainoisilla nuorilla miehillä ja siihen liittyy muita terveydelle haitallisia tekijöitä. Häiriintynyt syömiskäyttäytyminen tulisi huomioida itsessään ja erityisesti lihavuuden hoidossa. Miesten syömishäiriöoireilun arvioimiseen tarvitaan uusia menetelmiä.
Published: 2021

42. Lapsuuden liikunta näkyy aikuisen sydänterveydessä

Author: Haapala, Eero A.
Subjects: elintavat, liikuntafysiologia, ylipaino, lapset (ikäryhmät), aikuiset, fyysinen aktiivisuus, sydämen vajaatoiminta
Abstract: nonPeerReviewed
Published: 2021

43. Body weight and premature retirement : population-based evidence from Finland

Author: Viinikainen, Jutta, Tikka, Santtu, Laaksonen, Mikko, Jääskeläinen, Tuija, Böckerman, Petri, and Karvanen, Juha
Subjects: tupakointi, finland, eläkkeelle siirtyminen, työkyky, health status, ylipaino, labor market, työmarkkinat, body mass index procedure, painoindeksi, waist circumference
Abstract: Background Health status is a principal determinant of labour market participation. In this study, we examined whether excess weight is associated with withdrawal from the labour market owing to premature retirement. Methods The analyses were based on nationally representative data from Finland over the period 2001–15 (N ∼ 2500). The longitudinal data included objective measures of body weight (i.e. body mass index and waist circumference) linked to register-based information on actual retirement age. The association between the body weight measures and premature retirement was modelled using cubic b-splines via logistic regression. The models accounted for other possible risk factors and potential confounders, such as smoking and education. Results Excess weight was associated with an increased risk of premature retirement for both men and women. A closer examination revealed that the probability of retirement varied across the weight distribution and the results differed between sexes and weight measures. Conclusion Body weight outside a recommended range elevates the risk of premature retirement. peerReviewed
Published: 2021

44. Lapsiperheen vanhemman työ ja lapsen ylipainoriski

Author: Kattilakoski, Mira, Liljeroos, Hanna, Yhteiskuntatieteiden tiedekunta - Faculty of Social Sciences, and Tampere University
Subjects: lapset (ikäryhmät), ylipaino, Hoitotieteen maisteriohjelma - Master's Programme in Nursing Science, perheet, työ
Abstract: Lasten ylipaino on sekä Suomessa että kansainvälisesti merkittävä ja kasvava kansanterveydellinen ongelma, joka lisää monien sairauksien riskiä ja heikentää terveyteen liittyvää elämänlaatua. Vanhempien voimavarat ja perheen yksilöllinen tilanne vaikuttavat perheen mahdollisuuksiin ja motivaatioon toteuttaa ylipainoa ehkäiseviä elintapoja. Työssäkäyvien lapsiperheen vanhempien on jaettava voimavaransa ja aikansa perheen ja työelämän vaatimusten kesken. Se miten tämä onnistuu, vaikuttaa koko perheen hyvinvointiin. Tämä pro gradu -tutkielma on kaksiosainen. Ensimmäisen osan muodostaa systemaattinen kirjallisuuskatsaus, jonka tarkoituksena oli kuvata, miten lapsiperheen vanhemman työ on yhteydessä lapsen ylipainoon tai ylipainoriskiin. Katsauksen tavoitteena oli tuottaa tietoa, jonka avulla voidaan paremmin tunnistaa ja ohjata perheitä, joissa lapsilla on suurentunut riski ylipainoisuuteen. Kirjallisuuskatsauksen tiedonhaku tehtiin Nursing & Allied Health Database, Social Science Database, Cinahl ja PsycInfo-tietokannoista. Kirjallisuushaun lopullinen tulos oli 167 artikkelia. Sisäänottokriteerien perusteella katsaukseen valittiin 38 alkuperäistutkimusta, jotka käsittelivät vanhemman työn ja lapsen ylipainon välisiä yhteyksiä. Tutkielman toisen osan muodostaa julkaisuharkintaan lähetettävä tutkimusartikkeli: Työn ja perheen yhteensovittamisen yhteys 4-vuotiaan lapsen ylipainoon ja ylipainoisuutta ehkäiseviin ravitsemuksellisiin elintapoihin. Tutkimuksen tarkoituksena oli selvittää miten vanhemman kokemus työn ja perheen yhteensovittamisesta sekä taustatekijät ovat yhteydessä 4-vuotiaan lapsen ylipainoisuuteen ja ylipainoisuutta ehkäiseviin elintapoihin. Elintavoista tarkasteltiin lapsen kasvisten, hedelmien ja marjojen käyttöä sekä perheen yhteisiä aterioita. Lisäksi tarkasteltiin neuvolan terveydenhoitajan tuen tarpeen arviota lapsen elintapoihin liittyen. Tutkimuksen tavoitteena oli tuottaa tietoa, jonka avulla voidaan tunnistaa, tukea ja ohjata paremmin perheitä, joissa vanhemmat kokevat työn ja perheen yhteensovittamisen hankaluutta ja joiden lapsilla on ylipainoa tai riski ylipainoisuuteen sekä pohtia, miten lapsiperhepalveluja tulisi kehittää tähän tarpeeseen vastaamiseksi. Kirjallisuuskatsauksen tulosten mukaan vanhempien työhön käyttämä aika, työn epäsäännöllisyys, työelämän muutosten ajoitus, työssäkäynti verrattuna kotivanhemmuuteen sekä stressi työn ja perheen yhteensovittamisesta olivat yhteydessä lapsen ylipainoriskiin. Työ on erityisesti vanhemman ajankäyttöön liittyen yhteydessä lapsen ylipainoriskiin ja ylipainoriskiä lisääviin elintapoihin, kuten pikaruuan kulutukseen ja yhteisten aterioiden vähenemiseen. Lasten ylipainoisuuden ehkäisyssä ja hoidossa tulee ottaa huomioon perheen yksilölliset voimavarat myös työn ja perheen yhteensovittamisen haasteiden näkökulmasta. Paljon työskentelevien vanhempien lapsilla saattaa olla suurempi riski ylipainoisuuteen. Tutkielman tilastollisen osan aineistona käytettiin THL:n vuonna 2018 keräämää FinLapset -aineistoa, joka analysoitiin kvantitatiivisin menetelmin käyttäen SPSS-ohjelmistoa. Tutkimuksessa käytettävä aineisto muodostui lopulta niistä 2145 lapsesta, joilla oli lastenneuvolassa mukana olleen vanhemman vastaus käytettävissä, Avohilmon rekisteritieto ISO-BMIstä sekä vastannut vanhempi oli työelämässä vähintään keskimäärin 16 h viikossa. Aineiston kuvailuun käytettiin frekvenssejä ja prosenttiosuuksia. Ristiintaulukoinnin, khiin neliötestin ja logistisen regression avulla tarkasteltiin eri muuttujien yhteyksiä. Tulosten mukaan ylipainoisuus oli yleisempää pojilla ja matalammin koulutettujen vanhempien lapsilla. Lapset söivät useammin kasviksia, hedelmiä ja marjoja perheissä, joissa vanhemmalla oli korkeampi koulutus, säännöllinen työ tai vanhempi koki työmääränsä liian suureksi. Perheen yhteinen ateria syötiin päivittäin useammin niissä perheissä, joissa oli kaksi aikuista, vanhemmalla oli korkeampi koulutus tai säännöllinen työ. Kun vanhempi koki, ettei hänen työmääränsä ollut liian suuri, eikä hän kokenut laiminlyövänsä kotiasioita työnsä vuoksi, perheessä syötiin useammin yhteisiä aterioita. Terveydenhoitaja oli arvioinut useammin elintapoihin liittyvää tuen tarvetta perheillä, joilla oli ylipainoinen lapsi mutta työn ja perheen yhteensovittamista kuvaavat tekijät eivät olleet yhteydessä terveydenhoitajan tekemään arvioon lisätuen tarpeesta. Vanhempien kokema työn ja perheen yhteensovittamisen hankaluus ei näytä lisäävän lasten ylipainoisuutta, mutta voi vaikuttaa perheen ylipainoa ehkäisevien ravitsemuksellisten elintapojen toteutumiseen. Children's overweight, both in Finland and internationally, is a significant and growing public health problem that increases the risks of many diseases and reduces the quality of life related to health. Parent’s resources and the individual situation of the family affect the family’s opportunities and motivation to carry out a lifestyle that prevents overweight. Working parents must share their resources and time between the demands of work and family life as much as possible. The success of this affects the well-being of the whole family. This master's thesis has been divided into two parts. The first part consists of a systematic literature review with a purpose to describe the relation of parent's work to the child’s overweight or risk of overweight. The aim of the review was to provide information to better identify and guide families where children are at increased risk of obesity. Literature review information retrieval was performed from the Nursing & Allied Health Database, Social Science Database, Cinahl, and PsycInfo databases. The final result of the literature search was 167. Based on the inclusion criteria, 38 original studies on the links between parental work and child overweight were selected for the review. The second part of this master's thesis consists of a research article sent for publication consideration: Reconciling work and family and the risk of obesity in a 4-year-old child. The purpose of the study was to find out how the background factors and the parent's experience of reconciling work and family are related to a 4-year-old child's overweight and lifestyle that prevents overweight. Lifestyle choices included the child's use of vegetables, fruits, and berries, as well as having family meals. The purpose was also to provide information whether the counselor nurse had identified the need for additional support for these families. The aim of the study was to provide information on how to better identify, support and guide families in which parents find it difficult to reconcile work and family and whose children are overweight or at risk for obesity, and to consider how family services should be developed to meet this need. According to the results of the literature review the risk of overweight in children is associated with the time parents spent at work, the irregularity of work, the timing of changes in working life, working compared to home parenting, and the stress of reconciling work and family life. Especially when it comes to the parent’s use of time, work plays a significant role in the risk of child being overweight and in the lifestyle that increase the risk of being overweight, such as consuming fast food and having less family meals. The prevention and treatment of childhood obesity must also take into account the individual resources of the family from the perspective of the challenges of reconciling work and family. Children of parents who work a lot may be at a higher risk for being overweight. The material used in the quantitative part of the thesis was FinLapset data collected by the Finnish institute for health and welfare in 2018, which was analyzed by quantitative methods using SPSS software. The material used in the study eventually consisted of 2145 children after combining the Avohilmo registry data on ISO-BMI with the answers of parents involved in the child health care visit who worked an average of at least 16 hours per week. Frequencies and percentages were used to describe the data. Cross-tabulation, chi-square test, and logistic regression were used to examine the relationships between different variables. The results showed that overweight was more common in children of parents with low levels of education and boys. Children ate vegetables, fruits, and berries more often in families where the parent had a higher level of education, regular work, or the parent felt their workload was too large. A daily family meal was eaten more often in families with two adults or the parent having higher education or regular work. Family meals were eaten more often in families where the parent felt that his or her workload was not too great and he or she did not feel that the household was neglected because of work. The nurse had more often assessed lifestyle-related need for support in families with an overweight child, but factors describing work-family balance were not related to the nurse’s assessment of the need for additional support. The difficulty experienced by parents in reconciling work and family does not appear to increase childhood obesity but may affect the implementation of nutritional lifestyles that prevent family obesity.
Published: 2021

45. Maternal body mass index, change in weight status from childhood to late adulthood and physical activity in older age

Author: Mikaela B. von Bonsdorff, Anna P. Westberg, Minna K. Salonen, Niko Wasenius, Johan G. Eriksson, Department of General Practice and Primary Health Care, University of Helsinki, Helsinki University Hospital Area, Clinicum, Research Programs Unit, and Johan Eriksson / Principal Investigator
Subjects: Percentile, Aging, Pediatric Obesity, obesity, physical activity, raskaus, 030204 cardiovascular system & hematology, Overweight, liikunta, Metabolic equivalent, Body Mass Index, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Orthopedics and Sports Medicine, Mass index, Longitudinal Studies, 315 Sport and fitness sciences, Child, Finland, 2. Zero hunger, RISK, ylipaino, Middle Aged, äidit, TIME, maternal obesity, Female, medicine.symptom, fyysinen aktiivisuus, Physical activity, Mothers, Physical Therapy, Sports Therapy and Rehabilitation, lapset (ikäryhmät), terveyden edistäminen, DIET, 03 medical and health sciences, terveysvaikutukset, Humans, overweight, Exercise, Aged, business.industry, ENERGY-EXPENDITURE, 030229 sport sciences, Meth, lapsuus, medicine.disease, Obesity, Confidence interval, chemistry, 3121 General medicine, internal medicine and other clinical medicine, Linear Models, Body-Weight Trajectory, GAIN, business, Demography
Abstract: This study aimed to examine the longitudinal associations of maternal body mass index (BMI), weight status in childhood and late adulthood and device-measured total physical activity (TPA) in older age. The study involves 552 participants from Helsinki Birth Cohort Study who were born in Helsinki, Finland, in 1934-1944. TPA was measured with a multisensory body monitor at a mean age of 70 years and expressed in metabolic equivalent of task hours/day (METh/d). Childhood overweight (BMI > 85th percentile) was based on school health records at 6-7 years of age, and late adulthood overweight (BMI >= 25 kg/m(2)) was based on clinical measurements at the mean age of 61 years. Childhood overweight was associated with lower TPA, particularly in older women (mean difference -3.2 METh/d, 95% confidence interval (CI) -4.6 - -1.9), and late adulthood overweight was associated with lower TPA both in older women (mean difference -6.2, 95% CI (-7.2 - -5.1) and in older men (mean difference -2.6 METh/d, 95% CI -3.7 - -1.5). TPA in older age was highest in participants who were normal weight both in childhood and adulthood and lowest in participants who were overweight in childhood and adulthood. In participants with childhood overweight, TPA was lower in participants who were overweight both in childhood and adulthood compared to those who were overweight only in childhood. There was a U-shaped distribution of TPA according to maternal BMI in older women (P = .002), but not in older men. In conclusion, reaching normal weight after childhood predicted higher physical activity levels in older age.
Published: 2021

46. Obstetrisen potilaan kriittistä tilaa ennakoivat merkit. OEWS-seurannan merkitys synnytyksen jälkeisen sairastavuuden havaitsemisessa vaikeasti lihavilla naisilla

Author: Rissanen, Maria, Lääketieteen ja terveysteknologian tiedekunta - Faculty of Medicine and Health Technology, and Tampere University
Subjects: lapsivuodeaika, sairastavuus, Lääketieteen lisensiaatin tutkinto-ohjelma - Licentiate's Programme in Medicine, Obstetrinen, ylipaino, raskaus, seuranta, OEWS
Published: 2021

47. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

Author: Maryam Sharafkhah, Emanuel Zitt, Majid Ezzati, Luxia Zhang, Young-Ho Khang, Ellina Rakhimova, Kairit Mikkel, Tiina Vlasoff, Eruke E. Egbagbe, Sidsel Graff-Iversen, Ilona Nenko, Magdalena Klimek, Mathilde Savy, Sanjib Kumar Sharma, Alfonso Siani, Luís Lopes, Vanina Bongard, Gregor Jurak, Jacqueline F. Price, Christina-Paulina Lambrinou, Maria Lc Iurilli, Rainford J. Wilks, Bontha V. Babu, Fereidoun Azizi, Harunobu Nakamura, Marialaura Bonaccio, Angela Döring, Zhenyu Zhang, Naser Ahmadi, Jolanta Słowikowska-Hilczer, Ana Paula Carlos Cândido, Clive Osmond, Thirunavukkarasu Sathish, Robert J. Adams, Themistoklis Tzotzas, Reina Engle-Stone, Atul Trivedi, Shoichiro Tsugane, Niels Møller, Jorge Bezerra, Dénes Molnár, Muhammad Fadhli Mohd Yusoff, Badreya Al-Lahou, J. Jaime Miranda, Bahram Mohajer, Sigmund A. Anderssen, Lital Keinan Boker, Eero Kajantie, Martin Gulliford, Maties Torrent, Sumit Bharadwaj, Toshiharu Ninomiya, Zbigniew Gaciong, Nayu Ikeda, Li Juan Wu, Adrian Richter, Licia Iacoviello, Marc J. Gunter, Wenbin Wei, Norsyamlina Che Abdul Rahim, Eman Aly, Ambady Ramachandran, Nils Lehmann, Soile E. Puhakka, Giovanni Veronesi, Hongsheng Bi, Eiji Oda, Jia Li Duan, Per Tynelius, José María Huerta, Janne Schurmann Tolstrup, Rodrigo M. Carrillo-Larco, Rosangela Fernandes Lucena Batista, Victoria E Soto-Rojas, Hanno Ulmer, Shukri F. Mohamed, Anthony Kafatos, Suyeon Park, Mohsen Ibrahim, Hamed Pouraram, Bin Zhou, May Soe Aung, Lars Bo Andersen, Erfan Ghasemi, René Charles Sylva, Himanshu K. Chaturvedi, Luc Dauchet, Ahmad Ali Zainuddin, Angela Chetrit, Dan Zhu, Valérie Deschamps, Ko Ko Zaw, Peter Vollenweider, Tomas Vega, Yves Martin-Prével, Mahfuzar Rahman, Dorja Vočanec, Roman Topor-Madry, Vinay Nangia, Herculina S. Kruger, Asher Fawwad, Emily Sonestedt, Elena Pahomova, Aleksander Giwercman, Elżbieta Dziankowska-Zaborszczyk, Cecilia Björkelund, Tatjana Hejgaard, Maria Puiu, Maria Benedetta Donati, Andrew Wong, Carlos P. Boissonnet, Santosh K. Bhargava, Patrick Kolsteren, Dermot O'Reilly, Bahareh Kheiri, Wolfgang Kratzer, Susanne R. de Rooij, H. Bas Bueno-de-Mesquita, Günther Fink, José R. Banegas, Michele Monroy-Valle, Drude Molbo, Mahmudur Rahman, Hynek Pikhart, Rafael N. Pichardo, Massimo Salvetti, Hui Cai, Sarah Filippi, Georg Posch, Hung-Kwan So, Yonghua Hu, Katsuyasu Kouda, Joana Carvalho, Gailute Bernotiene, Hannu Uusitalo, Thein Thein Htay, Felix Kaducu, Maigeng Zhou, Lars Ängquist, Thi Tuyet-Hanh Tran, Charles Lunogelo, Michel Joffres, Sabina Zambon, Ronald D. Gregor, Vayia Rarra, Seyed Mohammad Hashemi-Shahri, Loreto Santa Marina, Galina Obreja, Rudolf Kaaks, Aya Mostafa, Maria do Carmo Franco, Beata Gurzkowska, Chien-Jen Chen, Marie Moitry, Nizal Sarrafzadegan, Xiangjun Wang, Diego Giulliano Destro Christofaro, Imperia Brajkovich, Fangfang Chen, Francesco Panza, Ling Yang, Holly E. Syddall, Cecily Kelleher, Michael Tornaritis, Ningli Wang, Lutgarde Thijs, Marjolein Visser, Angelika Schaffrath Rosario, María José Tormo, Jostein Steene-Johannessen, Norbert Amougou, Emmanuella Magriplis, Mar Alvarez-Pedrerol, Jingli Gao, Stig E. Bojesen, Giuseppe Grosso, Seongjun Ha, Lauren Lissner, Mikhail Benet, Anastasia Markaki, Sanjay Rampal, Antônio Augusto Moura da Silva, Maria Lorenza Muiesan, Angelique Chan, Yvonne T. van der Schouw, Annamari Lundqvist, Philippe Amouyel, Kristyna Zejglicova, Charalambos Hadjigeorgiou, João Breda, Jørgen Meisfjord, Fatima Zahra Laamiri, Carl Lachat, Kai-Uwe Saum, Vilma Irazola, Leng Huat Foo, Óscar Lopes, Dickman Gareta, Flavio Nervi, Imre Janszky, Ruzena Kubinova, Terho Lehtimäki, Mario V. Capanzana, Moyses Szklo, Ramfis Nieto-Martínez, Viswanathan Mohan, Shuohua Chen, Arvind Pandey, Luigi Palmieri, Roya Kelishadi, Srinivasan Kannan, Jie Mi, Robert Beaglehole, Liliana Dacica, Jyrki K. Virtanen, Mohan Deepa, Peter Ueda, Isti Ilmiati Fujiati, Hermann Pohlabeln, Morten Sodemann, Jytte Halkjær, Zbigniew Kułaga, Sophie Visvikis-Siest, Farshad Farzadfar, Mohsen Azimi-Nezhad, Henry Völzke, Karolina Milkowska, Zahra Mohammadi, Belgin Ünal, Magda Gasull, George S. Stergiou, Marshall K. Tulloch-Reid, Seppo Koskinen, James E. Bennett, Marcela González-Gross, Virginija Dulskiene, Idris Guessous, Assembekov Batyrbek, Kamarul Imran Musa, Jeannette Lee, Josep Redon, Bihungum Bista, Luisa M Macieira, Johan Sundström, Andres Metspalu, Lariane M Ono, Flora A. Ukoli, Salar Rahimikazerooni, Andrea Gualtieri, Trevor S. Ferguson, Félicité Tchibindat, Eliza Cinteza, Ha Tp Do, Tajana Zeljkovic Vrkic, Tuyen D Le, Alison J. Hayes, Abdul Basit, Chandini Nekkantti, Teresa Norat, Eunice Ugel, Gulmira Aitmurzaeva, Mariachiara Di Cesare, Abdul Hamid Zargar, Vincenzo Solfrizzi, Garry L. Jennings, Aline Meirhaeghe, Kaare Christensen, Päivi Mäki, Xu Lin, Ali Esmaeili, Joanna Baran, Aneta Grajda, Renata Cifkova, Alexandre C. Pereira, Martin Bobak, Iuliia A Rusakova, Keiu Nelis, Damian K Francis, Guansheng Ma, Axel C. Carlsson, Alejandro Diaz, Alireza Ansari-Moghaddam, N Capkova, Zumin Shi, Maria Turley, Imelda A. Agdeppa, Helena I. S. Nogueira, Marcia Scazufca, Katharina Maruszczak, Natascia Rinaldo, Paulo A. Lotufo, Nuno Lunet, Thor Aspelund, Caroline H.D. Fall, Antonio Cabrera de León, Ahmad Faudzi Yusoff, Holger Theobald, Beatriz D'Agord Schaan, Pedro Marques-Vidal, William A. Neal, Mihai Gafencu, Tandi E. Matsha, Ana B. Crujeiras, Ahmad Reza Dorosty, Alain Morejon, Weili Yan, Dominique Hange, Bekbolat Zholdin, Frédéric Gottrand, Jorge Mota, Jana Námešná, Stevo Popovic, Louise Eriksen, Line Lund Kårhus, Cihangir Erem, Juergen Breckenkamp, Mathilde Kersting, Yi Song, Martin McKee, Aleksandra Gomula, Rafaela Rosário, Enzo Manzato, S. Goya Wannamethee, Sounnia Mediene Benchekor, Azim Nejatizadeh, Krishna Kumar Aryal, Juan P. González-Rivas, Vedrana Sember, Stephen T. McGarvey, Jukka T. Salonen, Patrick Pasquet, Patricia Varona-Pérez, Amelia C. Crampin, Ramin Heshmat, Violeta Iotova, Juvenal Soares Dias-da-Costa, Oye Gureje, Aletta E. Schutte, João Luiz Bastos, Anelise Reis Gaya, Konrad Jamrozik, Dalia Luksiene, Amina Barkat, Maria Paula Santos, José Camolas, Azli Baharudin, Diego Vanuzzo, Doris Stöckl, Rosalynn Siantar, Jouko Saramies, Albertino Damasceno, Davood Khalili, Simona Bo, Martina Müller-Nurasyid, Dominique Cottel, Markku Peltonen, Fikru Tullu, Ana Isabel Rito, Angélica Ochoa-Avilés, Annette J. Dobson, Christopher T. Cowell, Charumathi Sabanayagam, Rildo de Souza Wanderley Júnior, Oanh T. H. Trinh, Farahnaz Joukar, Mostafa K. Mohamed, Mostafa Qorbani, Jeongseon Kim, Helmut Schröder, Machi Suka, Natasja M. van Schoor, Jussi Kauhanen, Teresa Haugsgjerd, Goodarz Danaei, M. Fernanda Lima-Costa, Yong Tao, Elisabetta L. Romeo, Grazyna Jasienska, Victor Guillermo Sequera, Kazem Mohammad, Yanina Zócalo, Fernanda Cunha Soares, Jianfeng Wu, Mohammad Esmaeel Motlagh, María Elena Díaz-Sánchez, Monika Zuziak, Eldridge Ferrer, Anette Varbo, Leila Beltrami Moreira, Jeremy M. Jacobs, Kenneth James, Elena Sacchini, Pascal Bovet, Mahboubeh Parsaeian, Tania Lopez, Ya Xing Wang, Wojciech Drygas, Jody C Miller, Svetlana A. Shalnova, Maria Elisa Zapata, Chung T Nguyen, Nimmathota Arlappa, Edwige Landais, Thorkild I. A. Sørensen, Jeannette Klimont, Amirabbas Momenan, Erik J. Timmermans, Mari-Liis Tammesoo, Jost B. Jonas, Stefania Toselli, Maria Teresa Anselmo Olinto, Bahman Cheraghian, Kouamelan Doua, Esteban Carmuega, Marjeta Mišigoj-Duraković, Bo Werner, M. Arfan Ikram, Breige A. McNulty, Christa Meisinger, Clara Homs, Namuna Shrestha, Alina Kerimkulova, Youcef Laid, Claes Ohlsson, Alicia Matijasevich, Alison J Price, Ala'a Alkerwi, Kristine H. Allin, Lorenza Pilotto, Mohannad Al Nsour, Ingunn Holden Bergh, Marianna Noale, Heba Fouad, Vilnis Dzerve, Novie O. Younger-Coleman, Peter Willeit, Andrea R. V. R. Horimoto, Freda Pitakaka, Habiba Ben Romdhane, Savvas C. Savva, Rajeev Gupta, Jennifer Servais, Cristina Padez, Sarah P. Garnett, Maria del Cristo Rodriguez-Perez, Michala Lustigová, Tien Yin Wong, Rosa Haghshenas, Jonathan Giovannelli, Christina Howitt, Marleen E. Hendriks, Fadia AlBuhairan, Huashuai Chen, Gretchen A Stevens, Luís B. Sardinha, David Goltzman, Jenny M. Kindblom, Karina Mary de Paiva, Yousef Khader, Eric Monterrubio-Flores, Rajendra Pradeepa, Yi-Ting Lin, Martin Neovius, Juan Francisco Miquel, Ellis Owusu-Dabo, Anil Poudyal, Marzieh Katibeh, Tanja Stocks, Veronica Mocanu, Ulla Roggenbuck, Robespierre Ribeiro, Gabriele Eiben, Mary Simon, Christine Cameron, Hamid Hakimi, Kamel Ajlouni, Jakub Stokwiszewski, Iulia Jurca Simina, Pietro Amedeo Modesti, Frederick C. W. Wu, Peter Kristensen, Charles Mondo, Felix Gutzwiller, Mariana Sbaraini, Martijn Huisman, Betina H. Thuesen, Queenie Chan, Antonisamy Belavendra, Artur Mazur, Ulf Ekelund, Laura A. Rodríguez-Villamizar, Marcos André Moura-dos-Santos, Jean Ferrières, Farhad Zamani, Shina Avi, Yves Kameli, Luis Paulo Gomes Mascarenhas, Aluísio J D Barros, Thomas Meinertz Dantoft, Hossein Poustchi, Farid Najafi, Giovanni de Gaetano, Azaliia M Tuliakova, Vera Lanska, Tint Swe Latt, Matthias Bopp, Abbas Rezaianzadeh, Rod Jackson, Johan Van der Heyden, Reecha Sofat, Koen Van Herck, Allan G. Hill, Con Burns, Emanuela Pettenuzzo, Ming-Dong Wang, Stela McLachlan, Ulrike Gehring, Ranko Stevanovic, Nagalla Balakrishna, Lekhraj Rampal, Marjolijn C. E. Bragt, Saeid Eslami, Napoleón Pérez-Farinós, G. K. Mini, Viktoria Anna Kovacs, Rosemarie Martin, Nahla Hwalla, Wei Zheng, Hoang Van Minh, Edward D Janus, Laetitia Huiart, Farhad Pourfarzi, Sudha Ramachandra Rao, Fred Paccaud, Marcia Makdisse, Aye Aye Sein, Enrique Gutiérrez-González, Yang Yang, Anneke Blokstra, Henrike Galenkamp, Jaume Marrugat, Nazan Yardim, Wan Nazaimoon Wan Mohamud, Jesús Ibarluzea, Julio Zuñiga Cisneros, Laura Lauria, Argyro Karakosta, Dragana P Jovic, Jun Hata, Elio Riboli, Piotr Bandosz, Xun Tang, Parvina Mukhtorova, Jean Dallongeville, Jean-Bernard Ruidavets, Anne Tjønneland, Guillermo Frontera, Rahul Malhotra, Thomas Ferrao, Aleksandra Piwońska, Dusan Grafnetter, Mette Rasmussen, Daniel Weghuber, Sherali Rakhmatulloev, Martine Vrijheid, Johann Willeit, Motahareh Kheradmand, Małgorzata Mossakowska, Lechaba Tshepo, Dongfeng Gu, Hyeon Chang Kim, Vilmundur Gudnason, Maria Forsner, Peter Bjerregaard, Leon A. Simons, Rachael McLean, Japhet Killewo, Ramón Suárez-Medina, Y Nikitin, Eng Joo Tan, Jean Claude Mbanya, Aroor Bhagyalaxmi, Renata Kuciene, Kairat Davletov, Jose Eugenio Lozano, Afshin Ostovar, Niloofar Peykari, Guy De Backer, Soheir H Ahmed, Nicholas J. Wareham, Sai Yin Ho, Constanta Huidumac Petrescu, Maria Hassapidou, Iris Pigeot, Myriam Galfo, Susana Cararo Confortin, Blanca Sandra Ruiz-Betancourt, W. M. Monique Verschuren, Catterina Ferreccio, Fabio Galvano, Leila Houti, Daniel Bia, Annika Rosengren, Marcin Rutkowski, Biruta Velika, Joana Araújo, Fernando Rigo, Angela Spinelli, Scott B. McLean, Shirin Djalalinia, Marie Kunešová, Boban Mugoša, Sania Nishtar, Mangesh S. Pednekar, Shahla AlDhukair, Helle-Mai Loit, Antonis Zampelas, Altan Onat, Maciej Banach, Shohreh Naderimagham, Hajer Aounallah-Skhiri, Maja Bæksgaard Jørgensen, Yin Guo, Ewelina Czenczek-Lewandowska, Parasmani Dasgupta, Elvis Oa Wambiya, Inge Huybrechts, Raimund Erbel, Jari Jokelainen, Ana P. Ortiz, Stefan Kiechl, Emmanuel Cohen, Caleb Ochimana, Shynar Abdrakhmanova, Laura Censi, Iqbal Bata, Geetha R Menon, Snehalatha Chamukuttan, Pedro Plans-Rubio, Domenico Palli, Ana Azevedo, Slawomir Koziel, Benoît Salanave, Parinaz Mehdipour, Shu Ti Chiou, Lela Sturua, Lubica Ticha, Felipe Vogt Cureau, Jin Soo Moon, Ming-Hui Zhao, Urho M. Kujala, Nathalie Michels, Ertugrul Celikcan, Jaakko Tuomilehto, Judith Benedics, Tobias F. Rinke de Wit, Agnès Le Port, Reza Homayounfar, Andrea Rodriguez-Martinez, Tai Hing Lam, Yn-Tz Sung, Jürgen König, Kodavanti Mallikharjuna Rao, Hazzaa M. Al-Hazzaa, Karen Morgan, Bogdan Wojtyniak, Cynthia M. Pérez, Ilse Khouw, Manoli Garcia-de-la-Hera, Dong Wook Shin, Genc Burazeri, Ausra Petrauskiene, Charles Sossa Jérome, Kenisha Russell Jonsson, José Boggia, Daniela Galeone, Alice Bonilla-Vargas, Han Cg Kemper, Rahman Shiri, Stefaan Demarest, Else Karin Grøholt, San-Lin You, Adelheid Weber, Juha Auvinen, Aida Pilav, Sibel Gogen, Suzanne N Morin, Wan Mohamad Wan Bebakar, Viviane Cunha Cardoso, Kavumpurathu Raman Thankappan, Hana Zamrazilová, Frank Claessens, Karien Stronks, Helen Gonçalves, Tahir Aris, Luis Revilla, Sérgio Viana Peixoto, Zhamilya Battakova, Jing Liu, Eliza Markidou Ioannidou, Leticia Hernandez Cadena, Priscilla Duboz, Sandjaja, Tiina Laatikainen, Rafel Ramos, Sareh Eghtesad, Judith Simons, Orn Olafsson, E. Shyong Tai, Louise A. Baur, Nihal Thomas, Aung Soe Htet, Bente Sparboe-Nilsen, Paul Elliott, Soon-Woo Park, Angel R. Gonzalez, Ying-Wei Wang, Rob M. van Dam, Ryutaro Ohtsuka, Ludmila Sevcikova, Suhaila Abdul Ghaffar, Lynell V Maniego, Fariborz Mansour-Ghanaei, Maria Dorobantu, Giovanni Viegi, Xiaoguang Yang, Honor Bixby, Prakash C. Gupta, Ofra Kalter-Leibovici, Eugene Sobngwi, Ričardas Radišauskas, Jurate Medzioniene, Roy A Wong-McClure, Kim F. Michaelsen, Antonia Trichopoulou, Tania Tello, Francesco Branca, Johanna Gunnlaugsdottir, Els Clays, Wei-Yen Lim, Suzanne C. Ho, Toomas Veidebaum, Rebecca Goldsmith, Margot González-León, Matthias Nauck, Alibek Mereke, Marta Buoncristiano, Jakob Tarp, Rosalba Rojas-Martínez, Maya Tanrygulyyeva, Reza Malekzadeh, Abdonas Tamosiunas, Dimitrios Poulimeneas, Pedro Ordunez, Isabelle Herter-Aeberli, Khanh Le Nguyen Bao, Anne Juolevi, Vassilis Zafiropulos, Emanuela Gualdi-Russo, Jordi Sunyer, Manu Raj, Chaoqiang Jiang, Sofia Malyutina, Efthymios Kapantais, Maria Lazo-Porras, Maung Maung Than Htike, Michael Hobbs, Ranjit Mohan Anjana, Merike Liivak, Johan G. Eriksson, Margarita Samoutian, Andreia N. Pizarro, Mohammed Rasoul Tarawneh, Jean Woo, Kaspar Staub, Maria Teresa Menzano, Mojtaba Farjam, Adroaldo Cesar Araujo Gaya, Mohammad El-khateeb, Zulfiqar A Bhutta, Mukharram M. Bikbov, Hsien-Ho Lin, Oscar Noboa, Thomas Waldhör, Garry Brian, Simona Costanzo, Frank Tanser, Nor Azwany Yaacob, Michelle Cilia, Ivo Rakovac, Bill Stavreski, Ioannis Pagkalos, Ivan Pećin, Carlo M. Barbagallo, Abla M. Sibai, Yuna He, Matsuda Fumihiko, Bharathi Viswanathan, Ali Reza Safarpour, Wei Cheng Lo, Abdullatif Husseini, Jiang He, Liv Elin Torheim, Nipa Rojroongwasinkul, Aicha Soumare, Astrid Petersmann, Tomasz Grodzicki, Davide Noto, Panayiotis K. Yiallouros, Kelias P. Msyamboza, William R. Tebar, Yingfeng Zheng, Eha Nurk, Bhawesh Koirala, Ana Jelakovic, Suhad Bahijri, Freja B Kampmann, Qi Sheng You, Marika Ferrari, María-Elena González-Villalpando, Aline Wagner, Olfa Saidi, Anwar Batieha, Eduardo Capuano, Coimbatore Subramaniam Shanthirani, Dong Wook Kim, Albina A Fakhretdinova, Tom Wilsgaard, Maria Avdicova, Moesijanti Soekatri, Chiara Donfrancesco, Salim Mohanna, Paola Russo, Uruwan Yamborisut, Rafael dos Santos Henrique, Martin Nankap, Allan Linneberg, Khairil Si-Ramlee, Kirsten Mehlig, Christina Mavrogianni, Raluca Pop, Lèlita Santos, Graziella Bruno, Valentina Peterkova, Iná S. Santos, Georg Lappas, Alberto Palloni, Malay K. Mridha, Andrzej Pajak, Marta García-Solano, Stefaan De Henauw, Daniel Ferrante, Rute Santos, Anders Grøntved, Lucjan Szponar, Mihaela Vladulescu, Chien-An Sun, Jan A. Staessen, Paula Duarte de Oliveira, Norazizah Ibrahim Wong, Maria Nordendahl, Elaine M. Dennison, Jeonghee Lee, Diego Salmerón, Ida Maria Schmidt, Gao Pei, Noushin Mohammadifard, Igor Spiroski, Fernando Rodríguez-Artalejo, Xu Ma, Elin Pettersen Sørgjerd, Valéria Regecová, Cláudia S. Minderico, Johanna A. Otero, Jamila Abubakar Garba, Vesselka Duleva, Rui Ornelas, Ilpo Huhtaniemi, Cesar G. Victora, Lijuan Liu, Rody G. Sy, Mahmood Moosazadeh, Ali Ahmadi, Antonio Pedro Graça, Natalia Nowak-Szczepanska, Miao Li Chee, Michael Sjöström, Charles Agyemang, Shiqi Zhen, Xiu-Hua Guo, Pawel Kurjata, Jardena J. Puder, Mehrdad Azmin, Neil Murphy, Kaosar Afsana, Alireza Sadjadi, Johanna M. Geleijnse, Prashant Mathur, Elysée Claude Bika Lele, Raphael Mendes Ritti-Dias, Yannis Manios, Majid Shirani, Rosemary B. Duda, Liis Nelis, Jurate Klumbiene, Zhengming Chen, Wichai Aekplakorn, Alun Evans, Andrzej Wiecek, Lars Lind, Denise Eldemire-Shearer, Bernardo L. Horta, Macia Enguerran, Seyed Rasoul Zakavi, Daniel Fernández-Bergés, Kumiko Ohara, Ursula Kiechl-Kohlendorfer, Hermann Brenner, Przemyslaw Slusarczyk, Espen Bjertness, Jutta Stieber, Augusto Di Castelnuovo, Joel G. R. Roy, Aryeh D. Stein, Ruth Frikke-Schmidt, Vera Musil, Amaneh Shayanrad, Marcel Goldberg, Ramon O. Jimenez, Mohammad Reza Fattahi, Jolanda Hyska, Amir Houshang Mehrparvar, Elin Kolle, Mohamed Bamoshmoosh, Michelle Holdsworth, Felipe F. Casanueva, Børge G. Nordestgaard, Niels Wedderkopp, Eva Corpeleijn, Elias F. Gudmundsson, Antonio Mistretta, Daniel Lemogoum, Larissa Pruner Marques, Slavica Sović, Olli T. Raitakari, Marco Aurélio Peres, Alexandra Cucu, Gregorio Varela-Moreiras, Janine Clarke, Andrea Gazzinelli, Mieczysław Litwin, Sara Schramm, Xenophon Theodoridis, Harshpal Singh Sachdev, Mohammad Reza Mirjalili, Dimitrios Papandreou, Peter T. Katzmarzyk, Benjamin Acosta-Cazares, Ben Schöttker, Prabhdeep Kaur, Norlaila Mustafa, Shariq Rashid Masoodi, Sadaf G. Sepanlou, Adolfo Rubinstein, Francis Delpeuch, Julianne Williams, Abbas Dehghan, Leanne M. Riley, Heloisa Bettiol, Gabriele Nagel, Ellisiv B. Mathiesen, Ekaterina Stoyanova, Alisha N. Wade, Zhamyila Usupova, Arnaud Chiolero, Oonagh Markey, Jacqueline Ramke, Elena Bogova, Niveen M E Abu-Rmeileh, Nguyen D Nguyen, Tomasz Zdrojewski, Marjo-Riitta Järvelin, Jose Sanchez-Abanto, Rômulo Araújo Fernandes, Lourdes Ribas-Barba, Nalan Uysal, Mohamad Hasnan Ahmad, Krista Fischer, Maria Wany Louzada Strufaldi, Ramiro Guerrero, Farnam Mohebi, Tran Quoc Bao, Flávio Danni Fuchs, Salim Berkinbayev, Enisa Kujundzic, Sari Voutilainen, Farzad Hadaegh, Robert Lundqvist, Saeid Safiri, Iraj Mohebbi, George Luiz Lins Machado-Coelho, Annette Peters, Gonzalo Valdivia, Magdalena Korzycka, Rajiv T Erasmus, Masanori Iwasaki, Charmaine A. Duante, Sheikh Mohammed Shariful Islam, Quang Ngoc La, Ricky Eddie, Petra Rust, Daniela Rodrigues, Dirk De Bacquer, Karen Sparrenberger, Agneta Sjöberg, Thet Thet Mu, Katarzyna Dereń, Cora L. Craig, Jorge Motta, Janina Petkeviciene, Boyd Swinburn, Paibul Suriyawongpaisal, Visnja Djordjic, Ramón Alberto Rascón-Pacheco, Pradeep Joshi, Daan Kromhout, Marius B. Bjertness, Stefano Marventano, Juel Jarani, Alireza Khosravi, Eva Martos, David De Ridder, Lizzy M. Brewster, Nico Dragano, Liam Smeeth, Kenji Shibuya, Emma Ruiz Moreno, Hashem Jaddou, Grzegorz Sobek, Dimitrios Trichopoulos, Marvin Cervantes-Loaiza, Abu Am Hanif, Elaine M. Murtagh, Carlos A. Aguilar-Salinas, Graziella D'Arrigo, Kyungwon Oh, Heiner Boeing, Regina Heidinger-Felso, André Luiz Sena Guimarães, Balkish M. Naidu, Avula Laxmaiah, Ana M. B. Menezes, Marie Eliasen, Francesco Pistelli, Yuan He, Dusko Bjelica, José A. Casajús, Guang Ning, Lutgart Braeckman, Dirk Vanderschueren, Jochanan Stessman, Ivana Radic, Yi Zeng, Hans Concin, Damaskini Valvi, Sari Hantunen, Catherine Kyobutungi, Diego Augusto Santos Silva, Wenhua Zhao, Sok King Ong, Anne W. Taylor, Iraj Nabipour, Justyna Godos, Cyrus Cooper, Mattias Johansson, Samuel C. Dumith, Magdalena Muc, Sabine Schipf, Idowu O Senbanjo, Jim Mann, Rajaa Al-Raddadi, Yih Chung Tham, Kay-Tee Khaw, Joseph Cacciottolo, Ana Henriques, Sahar Saeedi Moghaddam, Reza Mohammadpourhodki, Bernhard O. Boehm, Songhomitra Panda-Jonas, Iveta Pudule, Elisabete Ramos, Lacramioara Aurelia Brinduse, Paul H. Lee, Terence W O'Neill, Javad Aghazadeh-Attari, Margus Punab, Bojan Jelaković, Camilla T. Damsgaard, Takafumi Ishida, Ekaterina Chikova-Iscener, Mirjam M. Heinen, Tazeen H. Jafar, Semánová Csilla, Constance Schultsz, Santiago F. Gomez, Raija Korpelainen, Edward W. Gregg, Laura Gutierrez, Pierre Traissac, Victor M. Herrera, Aristides M. Machado-Rodrigues, Fatemeh Malekzadeh, Shouling Wu, Jennifer L. Baker, Clicerio González-Villalpando, Eleonora d'Orsi, Irene G. M. van Valkengoed, Anna Fijałkowska, Wen-Harn Pan, Gregor Starc, Meghnath Dhimal, Murat Topbaş, George Moschonis, Robert Eggertsen, Abdullah Alkandari, Quang Ngoc Nguyen, Janette Walton, Elnaz Faramarzi, Saeed Dastgiri, Lien Braeckevelt, Nasheeta Peer, Radka Taxová Braunerová, Mohamed M. Ali, Steiner Krokstad, Harald Geiger, Morteza Shamshirgaran, Lela Shengelia, María Ángeles Dal Re Saavedra, Silvana Donoso, Khem Bahadur Karki, Timothy J. Key, Maria G. Grammatikopoulou, Susana Vale, Felix K. Assah, Juan A Rivera, Peter H. Whincup, Oana-Florentina Gheorghe-Fronea, Cassiano Ricardo Rech, Paul Ferdinand M. Reganit, Rachakulla Hari Kumar, Jaakko Mursu, Luis A. Moreno, Glen Gironella, Jelena Kos, Tilema Cama, Haakon E. Meyer, Jun Ma, Raphael E. Arku, Ziad Abdeen, Dianna J. Magliano, Jitendra Jonnagaddala, Konstantinos Gkiouras, Paola Nardone, Alberto Barceló, Tomi-Pekka Tuomainen, Francesco Gianfagna, Stefania Maggi, Mohammad Hossein Somi, Behrooz Hamzeh, Miquel Porta, Vesna Jureša, Alexander D. Deev, David Faeh, Antonio Bernabe-Ortiz, Sirkka Keinänen-Kiukaanniemi, Ian Hambleton, Stefan Savin, Andre Pascal Kengne, R. Krishna Kumar, Kurt Widhalm, Marco M Ferrario, Parisa Amiri, Anjani Kumar Jha, Thamara Hubler Figueiró, Jana Kratenova, Claudia M. Hormiga, Maria Tsigga, Zivka Dika, Indrapal I. Meshram, Ei Ei K. Nang, Ian Rouse, Rusidah Selamat, Paul Korrovits, Grethe S. Tell, Julie Taylor, Anabela Mota-Pinto, Paolo Vineis, Kotsedi D Monyeki, Khuong Quynh Long, Frank J Rühli, Shelly R. McFarlane, Sara Santos Sanz, Edyta Łuszczki, Maria G. Stathopoulou, Tara Coppinger, Karin De Ridder, Lucie Viet, Anna Bugge, Mehdi Yaseri, Safiah Md Yusof, Sandra C. Fuchs, Muhammad Islam, Irfan Nuhoglu, Rui Providência, Bernard Maire, Leandra Abarca-Gómez, Sinead Brophy, Maria Ruiz-Castell, Daniela Pierannunzio, Cristina Taddei, Gowri Mahasampath, Gustavo Velasquez-Melendez, Hanna Tolonen, Sudhir Kowlessur, Bagher Larijani, Laura Torres-Collado, Susi Kriemler, Ali Akbar Shayesteh, Cynthia Robitaille, Jorge Escobedo-de la Peña, Yufang Bi, Chinh Nguyen Huu, Line Tang Møllehave, Vincent Jr DeGennaro, Noor Ani Ahmad, Anar Dushpanova, Agustinus Soemantri, Susana Sans, Ionela Pascanu, Gwenaëlle Le Coroller, Inger Ariansen, Kodanda R Kanala, Gert B. M. Mensink, Abhijit Sen, Sergej M. Ostojic, Hanan F. Abdul Rahim, Hélène Delisle, Francisco J. Félix-Redondo, Yadlapalli S. Kusuma, Michael Knoflach, Moein Yoosefi, Tanja G. M. Vrijkotte, Wolfgang Ahrens, Osvaldo Santos, Bethlehem D. Solomon, Erik Lykke Mortensen, Nikhil D. Patel, Reynaldo Martorell, Ching-Yu Cheng, Stine Schramm, Hana Shimizu-Furusawa, Jacek Jóźwiak, Radwan Qasrawi, Herman Borghs, Zhanna Kalmatayeva, Heidi Klakk, Akram Pourshams, Naomi S. Levitt, Son Thai Pham, Simona Giampaoli, Dong Zhao, Indah Suci Widyahening, Merete Osler, Paula Margozzini, Silvia Bel-Serrat, Dora Romaguera, Monira Alarouj, Winsome R. Parnell, Marloes Cardol, Giota Touloumi, Janice Luisa Lukrafka, Adela Chirita-Emandi, Maryam Kavousi, Sanja Musić Milanović, Jean-Michel Gaspoz, Jalila El Ati, Sauli Herrala, Liang Xu, Pilar Guallar-Castillón, Bee Koon Poh, Luis Serra-Majem, Jonathan E. Shaw, Belong Cho, Daphne Mirkopoulou, Salvador Villalpando, Yuki Fujita, Tiffany K. Gill, Nish Chaturvedi, Erkin M. Mirrakhimov, Günay Can, Mark Woodward, Esther Lopez-Garcia, Mauro Virgílio Gomes de Barros, Ahmed A. Madar, Shoaib Afzal, Melanie J. Cowan, Gareth Stratton, Eduardo Salazar Martinez, Sameer Narake, Norie Sawada, Deepak Amarapurkar, Deepa Weerasekera, Diana A. Santos, Marjeta Majer, Herman Schargrodsky, Bruna Gonçalves Cordeiro da Silva, Ebrahim Eftekhar, Jesús Vioque, Marisa K. Sophiea, Teresa Shamah-Levy, María Dolores Chirlaque, Mohd Azahadi Omar, Stefan Söderberg, Isabel O. Oliveira, Joanne Katz, Xingwang Ye, Christophe Tzourio, Marie Zins, Aneta Weres, Ulrich Keil, Haiquan Xu, Akihiro Yoshihara, Rachel Dankner, Gabriella Gruden, Maroje Sorić, Hanspeter Stamm, Kim Overvad, Yanping Li, Carsten Oliver Schmidt, Christa L. Lilly, Veikko Salomaa, Gilad Twig, Senthil K Vasan, Qian Wang, Liufu Cui, Andrzej Galbarczyk, Sylvain Sebert, Wilma M. Hopman, Karl-Heinz Jöckel, Ari Voutilainen, Peter Schnohr, Jerzy Chudek, Katia Vergetti Bloch, Vincenzo Capuano, Jyh Eiin Wong, Torben Jørgensen, Anja Schienkiewitz, Nader Saki, Carolina Tarqui-Mamani, Maria Cecília Formoso Assunção, Kazi M. Jamil, Juraci Almeida Cesar, Pedro J Ortiz, Delphine De Smedt, Luciana Zaccagni, Lynne M. Boddy, Jie Hao, David Alejandro González-Chica, Romana Roccaldo, Sara Magnacca, Peter Stehle, Victoria Farrugia Sant'Angelo, Gry Skodje, Maryam Keramati, Tabara Yasuharu, Ali Ghanbari, Gyulli M. Kazakbaeva, Takuro Furusawa, Felicia Cañete, Kari Kuulasmaa, Justina Vaitkeviciute, (NCD-RisC), NCD Risk Factor Collaboration, Imperial College London, Harvard T.H. Chan School of Public Health, Middlesex University [London], Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut 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Chiara Donfrancesco , Silvana P Donoso , Angela Döring , Maria Dorobantu , Ahmad Reza Dorosty , Kouamelan Doua , Nico Dragano , Wojciech Drygas , Jia Li Duan , Charmaine A Duante , Priscilla Duboz , Rosemary B Duda , Vesselka Duleva , Virginija Dulskiene , Samuel C Dumith , Anar Dushpanova , Vilnis Dzerve , Elzbieta Dziankowska-Zaborszczyk , Ricky Eddie , Ebrahim Eftekhar , Eruke E Egbagbe , Robert Eggertsen , Sareh Eghtesad , Gabriele Eiben , Ulf Ekelund , Mohammad El-Khateeb , Jalila El Ati , Denise Eldemire-Shearer , Marie Eliasen , Paul Elliott , Reina Engle-Stone , Macia Enguerran , Rajiv T Erasmus , Raimund Erbel , Cihangir Erem , Louise Eriksen , Johan G Eriksson , Jorge Escobedo-de la Peña , Saeid Eslami , Ali Esmaeili , Alun Evans , David Faeh , Albina A Fakhretdinova , Caroline H Fall , Elnaz Faramarzi , Mojtaba Farjam , Victoria Farrugia Sant'Angelo , Farshad Farzadfar , Mohammad Reza Fattahi , Asher Fawwad , Francisco J Felix-Redondo , Trevor S Ferguson , Romulo A Fernandes , Daniel Fernández-Bergés , Daniel Ferrante , Thomas Ferrao , Marika Ferrari , Marco M Ferrario , Catterina Ferreccio , Eldridge Ferrer , Jean Ferrieres , Thamara Hubler Figueiró , Anna Fijalkowska , Günther Fink , Krista Fischer , Leng Huat Foo , Maria Forsner , Heba M Fouad , Damian K Francis , Maria do Carmo Franco , Ruth Frikke-Schmidt , Guillermo Frontera , Flavio D Fuchs , Sandra C Fuchs , Isti I Fujiati , Yuki Fujita , Matsuda Fumihiko , Takuro Furusawa , Zbigniew Gaciong , Mihai Gafencu , Andrzej Galbarczyk , Henrike Galenkamp , Daniela Galeone , Myriam Galfo , Fabio Galvano , Jingli Gao , Manoli Garcia-de-la-Hera , Marta García-Solano , Dickman Gareta , Sarah P Garnett , Jean-Michel Gaspoz , Magda Gasull , Adroaldo Cesar Araujo Gaya , Anelise Reis Gaya , Andrea Gazzinelli , Ulrike Gehring , Harald Geiger , Johanna M Geleijnse , Ali Ghanbari , Erfan Ghasemi , Oana-Florentina Gheorghe-Fronea , Simona Giampaoli , Francesco Gianfagna , Tiffany K Gill , Jonathan Giovannelli , Glen 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, Zhanna Kalmatayeva , Ofra Kalter-Leibovici , Yves Kameli , Freja B Kampmann , Kodanda R Kanala , Srinivasan Kannan , Efthymios Kapantais , Argyro Karakosta , Line L Kårhus , Khem B Karki , Marzieh Katibeh , Joanne Katz , Peter T Katzmarzyk , Jussi Kauhanen , Prabhdeep Kaur , Maryam Kavousi , Gyulli M Kazakbaeva , Ulrich Keil , Lital Keinan Boker , Sirkka Keinänen-Kiukaanniemi , Roya Kelishadi , Cecily Kelleher , Han Cg Kemper , Andre P Kengne , Maryam Keramati , Alina Kerimkulova , Mathilde Kersting , Timothy Key , Yousef Saleh Khader , Davood Khalili , Kay-Tee Khaw , Bahareh Kheiri , Motahareh Kheradmand , Alireza Khosravi , Ilse Msl Khouw , Ursula Kiechl-Kohlendorfer , Stefan Kiechl , Japhet Killewo , Dong Wook Kim , Hyeon Chang Kim , Jeongseon Kim , Jenny M Kindblom , Heidi Klakk , Magdalena Klimek , Jeannette Klimont , Jurate Klumbiene , Michael Knoflach , Bhawesh Koirala , Elin Kolle , Patrick Kolsteren , Jürgen König , Raija Korpelainen , Paul Korrovits , Magdalena Korzycka , 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, Luxia Zhang , Zhen-Yu Zhang , Dong Zhao , Ming-Hui Zhao , Wenhua Zhao , Shiqi Zhen , Wei Zheng , Yingfeng Zheng , Bekbolat Zholdin , Maigeng Zhou , Dan Zhu , Marie Zins , Emanuel Zitt , Yanina Zocalo , Julio Zuñiga Cisneros , Monika Zuziak , Majid Ezzati , Sarah Filippi, Epidemiology, Iurilli, Maria LC, Zhou, Bin, Bennett, James E, Carrillo-Larco, Rodrigo M, Sophiea, Marisa K, Rodriguez-Martinez, Andrea, Bixby, Honor, Solomon, Bethlehem D, Taddei, Cristina, Danaei, Goodarz, Di Cesare, Mariachiara, Stevens, Gretchen A, Riley, Leanne M, Savin, Stefan, Cowan, Melanie J, Bovet, Pascal, Damasceno, Albertino, Chirita-Emandi, Adela, Hayes, Alison J, Ikeda, Nayu, Jackson, Rod T, Khang, Young-Ho, Laxmaiah, Avula, Liu, Jing, Miranda, J Jaime, Saidi, Olfa, Sebert, Sylvain, Sorić, Maroje, Starc, Gregor, Gregg, Edward W, Abarca-Gómez, Leandra, Abdeen, Ziad A, Abdrakhmanova, Shynar, Ghaffar, Suhaila Abdul, Rahim, Hanan F Abdul, Abu-Rmeileh, Niveen M, Garba, Jamila Abubakar, Acosta-Cazares, 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Cynthia, Roccaldo, Romana, Rodrigues, Daniela, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L, Rosario, Rafaela V, Rosengren, Annika, Rouse, Ian, Roy, Joel GR, Rubinstein, Adolfo, Rühli, Frank J, Ruidavets, Jean-Bernard, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Moreno, Emma Ruiz, Rusakova, Iuliia A, Jonsson, Kenisha Russell, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Sabanayagam, Charumathi, Sacchini, Elena, Sachdev, Harshpal S, Sadjadi, Alireza, Safarpour, Ali Reza, Safiri, Saeid, Saki, Nader, Salanave, Benoit, Martinez, Eduardo Salazar, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Samoutian, Margarita, Sánchez-Abanto, Jose, Sandjaja, null, Sans, Susana, Marina, Loreto Santa, Santos, Diana A, Santos, Ina S, Santos, Lèlita C, Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Sanz, Sara Santo, Saramies, Jouko L, Sardinha, Luis B, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savva, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schipf, Sabine, Schmidt, Carsten O, Schmidt, Ida Maria, Schnohr, Peter, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schutte, Aletta E, Sein, Aye Aye, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sequera, Victor, Serra-Majem, Lui, Servais, Jennifer, Ševcíková, Ludmila, Shalnova, Svetlana A, Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K, Shaw, Jonathan E, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Silva, Antonio M, Silva, Diego Augusto Santo, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöberg, Agneta, Sjöström, Michael, Skodje, Gry, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Söderberg, Stefan, Soekatri, Moesijanti YE, Soemantri, Agustinu, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Sørgjerd, Elin P, Jérome, Charles Sossa, Soto-Rojas, Victoria E, Soumaré, Aïcha, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A, Stamm, Hanspeter, Stathopoulou, Maria G, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stevanovic, Ranko, Stieber, Jutta, Stöckl, Dori, Stocks, Tanja, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Sturua, Lela, Suárez-Medina, Ramón, Suka, Machi, Sun, Chien-An, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Swinburn, Boyd A, Sy, Rody G, Syddall, Holly E, Sylva, René Charle, Szklo, Moyse, Szponar, Lucjan, Tai, E Shyong, Tammesoo, Mari-Lii, Tamosiunas, Abdona, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Braunerová, Radka Taxová, Taylor, Anne, Taylor, Julie, Tchibindat, Félicité, Tebar, William R, Tell, Grethe S, Tello, Tania, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thomas, Nihal, Thuesen, Betina H, Tichá, Lubica, Timmermans, Erik J, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Torheim, Liv Elin, Tormo, María José, Tornaritis, Michael J, Torrent, Matie, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Trichopoulos, Dimitrio, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsugane, Shoichiro, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Twig, Gilad, Tynelius, Per, Tzotzas, Themistokli, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Varona-Pérez, Patricia, Vasan, Senthil K, Vega, Toma, Veidebaum, Tooma, Velasquez-Melendez, Gustavo, Velika, Biruta, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesu, Virtanen, Jyrki K, Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Völzke, Henry, Voutilainen, Ari, Voutilainen, Sari, Vrijheid, Martine, Vrijkotte, Tanja GM, Wade, Alisha N, Wagner, Aline, Waldhör, Thoma, Walton, Janette, Wambiya, Elvis OA, Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, de Souza Wanderley Júnior, Rildo, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nichola, Weber, Adelheid, Wedderkopp, Niel, Weerasekera, Deepa, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yaseri, Mehdi, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K, Yoosefi, Moein, Yoshihara, Akihiro, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O, Md Yusof, Safiah, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassili, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antoni, Zamrazilová, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Ko Zaw, Ko, Zdrojewski, Tomasz, Zejglicova, Kristyna, Vrkic, Tajana Zeljkovic, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Cisneros, Julio Zuñiga, Zuziak, Monika, Ezzati, Majid, Filippi, Sarah, Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Subjects: Population -- Health aspects, Leanness, Baixo peso/Underweight, none, Double burden, alipainoisuus, tulotaso, global health, systematic analysis, Sedentary behaviors, RC1200, Prospective associations, 0302 clinical medicine, underweight, nälänhätä, Biology (General), skin and connective tissue diseases, Children, ComputingMilieux_MISCELLANEOUS, Body mass index, Human Nutrition & Health, education.field_of_study, Humane Voeding & Gezondheid, ylipaino, General Medicine, kansainvälinen vertailu, 3. Good health, World health, Medicine, A100 Pre-clinical Medicine, Population distribution, medicine.medical_specialty, QH301-705.5, Science, Socio-culturale, Nursing, Social sciences, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Thinness, SDG 3 - Good Health and Well-being, BMI, epidemiology, obesity, None, Humans, Obesidade/Obesity, SDG 2 - Zero Hunger, education, VLAG, US adults, Omvårdnad, body mass index, malnutrition, obesity, underweight, nutritional and metabolic diseases, medicine.disease, terveellisyys, Obesity, Faculdade de Ciências Sociais, Body Mass Index, Prevalence, Risk Factors, General Biochemistry, WIAS, lihavuus, RA, Demography, N.A, double burden, Settore MED/09 - Medicina Interna, alueelliset erot, Nutrition and Disease, Animal Nutrition, [SDV]Life Sciences [q-bio], Medizin, 030204 cardiovascular system & hematology, 0601 Biochemistry and Cell Biology, Change distribution of body mass index, RA0421, Voeding en Ziekte, Epidemiology, Medicine and Health Sciences, Global health, Índice de massa corporal/Body Mass Index, 030212 general & internal medicine, Underweight, painoindeksi, 2. Zero hunger, General Neuroscience, aliravitsemus, elintarvikkeet, health, Public Health, Global Health, Social Medicine and Epidemiology, Diervoeding, 3142 Public health care science, environmental and occupational health, purl.org/pe-repo/ocde/ford#3.01.03 [https], Chinese adults, pooled analysis, medicine.symptom, Diet quality, B120 Physiology, Research Article, trends, purl.org/pe-repo/ocde/ford#1.06.03 [https], prevalence, Population, Mothers, Genetics and Molecular Biology, 3121 Internal medicine, medicine, Life Science, ddc:610, 3125 Otorhinolaryngology, ophthalmology, kehonkoostumus, Nutrition, Australian adults, General Immunology and Microbiology, purl.org/pe-repo/ocde/ford#3.01.04 [https], Ciências sociais, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Malnutrition, Epidemiology and Global Health, sense organs, Estilos de Vida e Impacto na Saúde
Abstract: From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions., Wellcome Trust, Medical Research Council, peer-reviewed
Published: 2021
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48. Liikunnallisuus ja hyvä kunto ehkäisevät tyypin 2 diabetesta ja valtimotautien riskitekijöitä lapsesta lähtien

Author: Väistö, Juuso, Haapala, Eero, and Lakka, Timo A.
Subjects: Physical actvivity and Nutrition in Children (PANIC), rasvamaksa, liikkumattomuus, ylipaino, lapset (ikäryhmät), riskitekijät, liikunta, fyysinen kunto, sepelvaltimotauti, kansanterveys, ennaltaehkäisy, aikuistyypin diabetes, metabolinen oireyhtymä, fyysinen aktiivisuus
Abstract: Lasten ylipaino on saavuttanut epidemian mittasuhteet maailmanlaajuisesti. Vaikka viime vuosina tilanne on hiukan parantunut, ylipaino on edelleen yksi merkittävimmistä kansanterveydellisistä ongelmista. Riskitekijöiden kasautumisen ehkäisy ja hoito tulisi aloittaa mahdollisimman varhain: mielellään jo sikiöaikana tai viimeistään varhaislapsuudessa. nonPeerReviewed
Published: 2021

49. Sosiaalista mediaa hyödyntävä elintapaohjausintervention kehittäminen ylipainoisille nuorille.

Author: RUOTSALAINEN, HEIDI, KÄÄRIÄINEN, MARIA, TAMMELIN, TUIJA, and KYNGÄS, HELVI
Subjects: PREVENTION of childhood obesity, BEHAVIOR modification, DIET, HEALTH behavior, INTERVIEWING, PATIENT compliance, SYSTEMATIC reviews, RANDOMIZED controlled trials, MOTIVATIONAL interviewing, SOCIAL media, PHYSICAL activity, ADOLESCENCE
Published: 2014

50. Physical Activity and Physical Competence in Overweight and Obese Children: An Intervention Study

Author: Laura Bortoli, Angelo Campanozzi, Montse C. Ruiz, Claudio Robazza, Irene Rutigliano, and Milena Morano
Subjects: Male, Pediatric Obesity, obesity, Health, Toxicology and Mutagenesis, Health Behavior, Psychological intervention, lcsh:Medicine, Overweight, Physical education, 0302 clinical medicine, 030212 general & internal medicine, Child, elämäntapa, kunto, school-based intervention, actual physical abilities, fitness, perceived physical abilities, healthy habits, Physical Education and Training, Schools, ylipaino, Female, medicine.symptom, Psychology, Psychosocial, fyysinen aktiivisuus, Clinical psychology, Best practice, education, lapset (ikäryhmät), Childhood obesity, Article, 03 medical and health sciences, medicine, Humans, Competence (human resources), Exercise, Life Style, interventio, lcsh:R, Public Health, Environmental and Occupational Health, 030229 sport sciences, medicine.disease, Obesity, terveellisyys, Physical Fitness, terveyskäyttäytyminen, lihavuus
Abstract: With the current obesity epidemic and the decline of fitness among school-aged children, the importance of obesity interventions to promote physical activity and healthy habits has become indisputable. The purpose of this study was to assess the efficacy of a school-based multicomponent intervention in increasing physical activity (PA) levels, actual physical abilities, and perceived physical abilities in clinical and nonclinical samples of overweight/obese boys and girls aged 10–12 years. The clinical intervention group (n = 35) participated in a 7-month after-school program in addition to curricular physical education lessons, while the nonclinical control group (n = 29) received usual curricular lessons. Measures included levels of PA and fitness and individual’s perceptions of physical ability. After treatment, the intervention group showed improved PA levels, perceived physical ability, and throwing and jumping task performances compared to the control group. Results indicate that a multicomponent program can improve levels of PA, fitness, and perceived competence of overweight participants. Findings highlight the importance of a comprehensive healthy lifestyle program that includes physical, psychosocial, and behavioral factors and suggest practical implications for educators, trainers, and teachers in identifying best practices targeting childhood obesity.
Published: 2020

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