343 results on '"van der Wal, M"'
Search Results
2. Chronically Activated T-cells Retain Their Inflammatory Properties in Common Variable Immunodeficiency
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Berbers, Roos-Marijn, van der Wal, M. Marlot, van Montfrans, Joris M., Ellerbroek, Pauline M., Dalm, Virgil A. S. H., van Hagen, P. Martin, Leavis, Helen L., and van Wijk, Femke
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- 2021
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3. Psychometric properties of the Dutch-Flemish PROMIS® pediatric item banks Anxiety and Depressive Symptoms in a general population
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Klaufus, L. H., Luijten, M. A. J., Verlinden, E., van der Wal, M. F., Haverman, L., Cuijpers, P., Chinapaw, M. J. M., and Terwee, C. B.
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- 2021
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4. Improvement in left ventricular ejection fraction after pharmacological up-titration in new-onset heart failure with reduced ejection fraction
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Nauta, J. F., Santema, B. T., van der Wal, M. H. L., Koops, A., Warink-Riemersma, J., van Dijk, K., Inkelaar, F., Prückl, S., Suwijn, J., van Deursen, V. M., Meijers, W. C., Coster, J., Westenbrink, B. D., de Boer, R. A., Hummel, Y., van Melle, J., van Veldhuisen, D. J., van der Meer, P., and Voors, A. A.
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- 2021
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5. Redenen om niet te vaccineren in Amsterdam en Amstelland
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Schellekens, M. H. F. T., Stegeman, H., van der Wal, M. F., van Rijn, R. C., Nielen, A. M. A., and Schim van der Loeff, M. F.
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- 2021
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6. Exploring the association between self-care behaviour, knowledge and cognition in patients with heart failure: a secondary analysis from the HF-Wii study
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Stromberg, A, primary, Van Der Wal, 'M, additional, and Jaarsma, T, additional
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- 2023
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7. IgE levels in patients with atopic dermatitis steadily decrease during treatment with dupilumab regardless of dose interval
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Dekkers, Coco, primary, van der Wal, M. Marlot, additional, van den Noort, Leonie, additional, Bakker, Daphne S., additional, de Bruin‐Weller, Marjolein, additional, and van Wijk, Femke, additional
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- 2023
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8. Schizofreniespectrum- en andere psychotische stoornissen
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van der Wal, M. S., Blanken, C., editor, Clijsen, M., editor, Garenfeld, W., editor, te Paske, I., editor, and van Piere, M., editor
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- 2016
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9. IgE levels in patients with atopic dermatitis steadily decrease during treatment with dupilumab regardless of dose interval
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Infection & Immunity, MS Dermatologie/Allergologie, CTI Van Wijk, Unit Opleiding Dermatologie, Child Health, Dekkers, Coco, van der Wal, M Marlot, van den Noort, Leonie, Bakker, Daphne S, de Bruin-Weller, Marjolein, van Wijk, Femke, Infection & Immunity, MS Dermatologie/Allergologie, CTI Van Wijk, Unit Opleiding Dermatologie, Child Health, Dekkers, Coco, van der Wal, M Marlot, van den Noort, Leonie, Bakker, Daphne S, de Bruin-Weller, Marjolein, and van Wijk, Femke
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- 2023
10. Biological Tipping Point in Patients with Atopic Dermatitis Treated with Different Dosing Intervals of Dupilumab
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MS Dermatologie/Allergologie, Infection & Immunity, CTI Van Wijk, Apotheek KF TDM, Apotheek Klinische Farmacie, Unit Opleiding Dermatologie, Child Health, Dekkers, Coco, van der Wal, M Marlot, El Amrani, Mohsin, van Luin, Matthijs, Bakker, Daphne S, de Bruin-Weller, Marjolein, van Wijk, Femke, MS Dermatologie/Allergologie, Infection & Immunity, CTI Van Wijk, Apotheek KF TDM, Apotheek Klinische Farmacie, Unit Opleiding Dermatologie, Child Health, Dekkers, Coco, van der Wal, M Marlot, El Amrani, Mohsin, van Luin, Matthijs, Bakker, Daphne S, de Bruin-Weller, Marjolein, and van Wijk, Femke
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- 2023
11. 025 Immunological changes in atopic dermatitis patients treated with different dosing intervals of dupilumab
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Dekkers, C., primary, van der Wal, M., additional, Bakker, D., additional, van Luin, M., additional, El Amrani, M., additional, de Bruin-Weller, M., additional, and van Wijk, F., additional
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- 2022
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12. Alcohol- en drugsgebruik onder 16- tot en met 18-jarige scholieren in Amsterdam
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Dijkshoorn, H., Schilthuis, W., van der Spek, N., and van der Wal, M. F.
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- 2017
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13. T cell interaction with activated endothelial cells primes for tissue-residency
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Wienke, Judith, primary, Veldkamp, Saskia R., additional, Struijf, Eva M., additional, Yousef Yengej, Fjodor A., additional, van der Wal, M. Marlot, additional, van Royen-Kerkhof, Annet, additional, and van Wijk, Femke, additional
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- 2022
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14. Improved tools for design and management of inland waterways
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International Navigation Congress (30th : 2002 : Sydney, N.S.W.), Janssen, PC, and van der Wal, M
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- 2002
15. Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response
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Lerkvaleekul, Butsabong, Veldkamp, Saskia R., Van Der Wal, M. Marlot, Schatorj, Ellen J.H., Kamphuis, Sylvia S.M., Van Den Berg, J. Merlijn, Hissink Muller, Petra C.E., Armbrust, Wineke, Vastert, Sebastiaan J., Wienke, Judith, Jansen, Marc H.A., Van Royen-Kerkhof, Annet, Van Wijk, Femke, Lerkvaleekul, Butsabong, Veldkamp, Saskia R., Van Der Wal, M. Marlot, Schatorj, Ellen J.H., Kamphuis, Sylvia S.M., Van Den Berg, J. Merlijn, Hissink Muller, Petra C.E., Armbrust, Wineke, Vastert, Sebastiaan J., Wienke, Judith, Jansen, Marc H.A., Van Royen-Kerkhof, Annet, and Van Wijk, Femke
- Abstract
Objective: JDM is a rare chronic immune-mediated inflammatory disease with a predominant role for type I IFN responses. We aimed to determine the potential of Siglec-1 expression on monocytes as a novel IFN-inducible biomarker for disease activity monitoring and prediction of treatment response in patients with JDM. Methods: Siglec-1 was measured by flow cytometry on circulating monocytes of 21 newly diagnosed JDM patients before start of treatment and, for 10 of these, also during follow-up. The expression levels of five type I IFN-stimulated genes, MX1, IFI44, IFI44L, LY6E and IFIT3, were measured by RT-qPCR to determine the IFN signature and calculate an IFN score. IFN-inducible plasma proteins CXCL10 and galectin-9 were measured by multiplex immunoassay. Results: Siglec-1 and IFN score were increased in JDM patients compared with controls and correlated with clinical disease activity. Stratification of patients by Siglec-1 expression at diagnosis identified those with high Siglec-1 expression as having a higher risk of requiring treatment intensification within the first 3 months after diagnosis (55% vs 0% of patients, P = 0.01). Siglec-1 expression strongly correlated with plasma levels of previously validated biomarkers CXCL10 (rs = 0.81, P < 0.0001) and galectin-9 (rs = 0.83, P < 0.0001), and was superior to the IFN score in predicting treatment response (area under the curve 0.87 vs 0.53, P = 0.01). Conclusion: Siglec-1 on monocytes is a novel IFN-inducible biomarker in JDM that correlates with clinical disease activity and identifies patients at risk for a suboptimal treatment response. Further studies are required to validate these findings and their clinical potential.
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- 2022
16. T cell interaction with activated endothelial cells primes for tissue-residency
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CTI Van Wijk, Infection & Immunity, MMB Research line 1, Nefro Vasculaire Geneeskunde, Child Health, Wienke, Judith, Veldkamp, Saskia R, Struijf, Eva M, Yousef Yengej, Fjodor A, van der Wal, M Marlot, van Royen-Kerkhof, Annet, van Wijk, Femke, CTI Van Wijk, Infection & Immunity, MMB Research line 1, Nefro Vasculaire Geneeskunde, Child Health, Wienke, Judith, Veldkamp, Saskia R, Struijf, Eva M, Yousef Yengej, Fjodor A, van der Wal, M Marlot, van Royen-Kerkhof, Annet, and van Wijk, Femke
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- 2022
17. Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint
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Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, CTI Van Loosdregt, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Child Health, Immuno/reuma onderzoek 5 (Vastert2), CTI Research, Immuno/reuma onderzoek 3 (Loosdregt), Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir-Farzin, van Loosdregt, Jorg, van Wijk, Femke, Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, CTI Van Loosdregt, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Child Health, Immuno/reuma onderzoek 5 (Vastert2), CTI Research, Immuno/reuma onderzoek 3 (Loosdregt), Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir-Farzin, van Loosdregt, Jorg, and van Wijk, Femke
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- 2022
18. Ocular surface disease is common in moderate-to-severe atopic dermatitis patients
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MS Dermatologie/Allergologie, Infection & Immunity, Unit Opleiding Dermatologie, MS Oogheelkunde, Other research (not in main researchprogram), CTI Van Wijk, Child Health, Biostatistiek Onderzoek, Julius Centrum, Achten, Roselie E, Bakker, Daphne S, van Luijk, Chantal M, van der Wal, M Marlot, de Graaf, Marlies, van Wijk, Femke, Zuithoff, Nicolaas P A, van der Rijst, Lisa P, Boesjes, Celeste M, Thijs, Judith L, de Boer, Joke H, de Bruin-Weller, Marjolein S, MS Dermatologie/Allergologie, Infection & Immunity, Unit Opleiding Dermatologie, MS Oogheelkunde, Other research (not in main researchprogram), CTI Van Wijk, Child Health, Biostatistiek Onderzoek, Julius Centrum, Achten, Roselie E, Bakker, Daphne S, van Luijk, Chantal M, van der Wal, M Marlot, de Graaf, Marlies, van Wijk, Femke, Zuithoff, Nicolaas P A, van der Rijst, Lisa P, Boesjes, Celeste M, Thijs, Judith L, de Boer, Joke H, and de Bruin-Weller, Marjolein S
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- 2022
19. The effect of neighbourhood income and deprivation on pregnancy outcomes in Amsterdam, The Netherlands
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Agyemang, C, Vrijkotte, T G M, Droomers, M, van der Wal, M F, Bonsel, G J, and Stronks, K
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- 2009
20. Human regulatory T-cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint
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Lutter, Lisanne, primary, van der Wal, M. Marlot, additional, Brand, Eelco C., additional, Maschmeyer, Patrick, additional, Vastert, Bas, additional, Mashreghi, Mir-Farzin, additional, van Loosdregt, Jorg, additional, and van Wijk, Femke, additional
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- 2022
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21. Heart failure patientsʼ future expectations and their association with disease severity, quality of life, depressive symptoms and clinical outcomes
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van der Wal, M. H. L., Strömberg, A., van Veldhuisen, D. J., and Jaarsma, T.
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- 2016
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22. Privacy services toegepast op bedrijfsprocessen als methode om te blijven voldoen aan de regels van de AVG
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van der Wal, M.
- Subjects
rechten van de betrokkene ,bedrijfsproces ,privacy services ,AVG - Abstract
Sinds de invoering van de Algemene Verordening Gegevensbescherming (AVG) in 2018 staat iedere onderneming die persoonsgegevens verwerkt, voor de uitdaging om aan deze wetgeving te voldoen en te blijven voldoen. Een persoon wiens gegevens worden verwerkt heeft rechten op deze gegevens, deze rechten staan beschreven in hoofdstuk 3 van de AVG “Rechten van de betrokkene”. De onderneming die persoonsgegevens verwerkt zal als verwerkingsverantwoordelijke gehoor moeten geven aan deze rechten en aan moeten kunnen tonen dat ze deze rechten conform de AVG faciliteren en wel met zo min mogelijk fouten en zonder te veel inspanning. Het verwerken van persoonsgegevens vindt plaats binnen het uitvoeren van bedrijfsprocessen en een kant en klare methode voor het operationaliseren van deze rechten binnen de dagelijkse bedrijfsprocessen van de onderneming is daarom wenselijk. In dit onderzoek is getracht hier een methode voor aan te reiken via het gebruik van privacy services. Allereerst zijn privacy services uit hoofdstuk 3 van de AVG geïdentificeerd; vastgelegd in een conceptueel model en getoetst aan modellen binnen de bestaande literatuur. Door dit conceptuele model, met de gevonden concepten en relaties, vervolgens toe te passen op een primair bedrijfsproces binnen een onderneming middels een case study, wordt getoetst of dit een bruikbare methode is bij het voldoen aan de wetgeving van de AVG en het kunnen aantonen daarvan. De bevindingen van de case study worden gegeneraliseerd als een methode voor het operationaliseren van de wettelijke eisen van hoofdstuk 3 van de AVG.
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- 2021
23. The effect of pre-operative blood withdrawal, with or without sequestration, on allogeneic blood product requirements
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van der Wal, M T, Boks, R H, Wijers-Hille, M J, Hofland, J, Takkenberg, J JM, and Bogers, A JJC
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- 2015
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24. Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint.
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Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir‐Farzin, van Loosdregt, Jorg, and van Wijk, Femke
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REGULATORY T cells , *JOINT pain , *JUVENILE idiopathic arthritis , *SYNOVIAL fluid , *AUTOIMMUNE diseases , *EXPERIMENTAL arthritis - Abstract
Objective: Tregs are crucial for immune regulation, and environment‐driven adaptation of effector (e)Tregs is essential for local functioning. However, the extent of human Treg heterogeneity in inflammatory settings is unclear. Methods: We combined single‐cell RNA‐ and TCR‐sequencing on Tregs derived from three to six patients with juvenile idiopathic arthritis (JIA) to investigate the functional heterogeneity of human synovial fluid (SF)‐derived Tregs from inflamed joints. Confirmation and suppressive function of the identified Treg clusters was assessed by flow cytometry. Results: Four Treg clusters were identified; incoming, activated eTregs with either a dominant suppressive or cytotoxic profile, and GPR56+CD161+CXCL13+ Tregs. Pseudotime analysis showed differentiation towards either classical eTreg profiles or GPR56+CD161+CXCL13+ Tregs supported by TCR data. Despite its most differentiated phenotype, GPR56+CD161+CXCL13+ Tregs were shown to be suppressive. Furthermore, BATF was identified as an overarching eTreg regulator, with the novel Treg‐associated regulon BHLHE40 driving differentiation towards GPR56+CD161+CXCL13+ Tregs, and JAZF1 towards classical eTregs. Conclusion: Our study reveals a heterogeneous population of Tregs at the site of inflammation in JIA. SF Treg differentiate to a classical eTreg profile with a more dominant suppressive or cytotoxic profile that share a similar TCR repertoire, or towards GPR56+CD161+CXCL13+ Tregs with a more distinct TCR repertoire. Genes characterising GPR56+CD161+CXCL13+ Tregs were also mirrored in other T‐cell subsets in both the tumor and the autoimmune setting. Finally, the identified key regulators driving SF Treg adaptation may be interesting targets for autoimmunity or tumor interventions. [ABSTRACT FROM AUTHOR]
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- 2022
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25. Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response
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Lerkvaleekul, Butsabong, primary, Veldkamp, Saskia R, additional, van der Wal, M Marlot, additional, Schatorjé, Ellen J H, additional, Kamphuis, Sylvia S M, additional, van den Berg, J Merlijn, additional, Hissink Muller, Petra C E, additional, Armbrust, Wineke, additional, Vastert, Sebastiaan J, additional, Wienke, Judith, additional, Jansen, Marc H A, additional, van Royen-Kerkhof, Annet, additional, and van Wijk, Femke, additional
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- 2021
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26. Chronically Activated T-cells Retain Their Inflammatory Properties in Common Variable Immunodeficiency
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Lab Reumatologie/Klinische Immunologie, Infection & Immunity, CTI Van Wijk, Immuno/reuma patientenzorg, Child Health, MS Interne Geneeskunde, MS Reumatologie/Immunologie/Infectie, Berbers, Roos-Marijn, van der Wal, M Marlot, van Montfrans, Joris M, Ellerbroek, Pauline M, Dalm, Virgil A S H, van Hagen, P Martin, Leavis, Helen L, van Wijk, Femke, Lab Reumatologie/Klinische Immunologie, Infection & Immunity, CTI Van Wijk, Immuno/reuma patientenzorg, Child Health, MS Interne Geneeskunde, MS Reumatologie/Immunologie/Infectie, Berbers, Roos-Marijn, van der Wal, M Marlot, van Montfrans, Joris M, Ellerbroek, Pauline M, Dalm, Virgil A S H, van Hagen, P Martin, Leavis, Helen L, and van Wijk, Femke
- Published
- 2021
27. Early and Long-Term Effects of Dupilumab Treatment on Circulating T-Cell Functions in Patients with Moderate-to-Severe Atopic Dermatitis
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MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, Infection & Immunity, CTI Van Wijk, CTI UDAIR, CTI Borghans, CDL Patiëntenzorg MI, CTI Research, Cancer, Child Health, Bakker, D S, van der Wal, M M, Heeb, L E M, Giovannone, B, Asamoah, M, Delemarre, E M, Drylewicz, J, Nierkens, S, Boyman, O, de Bruin-Weller, M S, Thijs, J L, Wijk, F van, MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, Infection & Immunity, CTI Van Wijk, CTI UDAIR, CTI Borghans, CDL Patiëntenzorg MI, CTI Research, Cancer, Child Health, Bakker, D S, van der Wal, M M, Heeb, L E M, Giovannone, B, Asamoah, M, Delemarre, E M, Drylewicz, J, Nierkens, S, Boyman, O, de Bruin-Weller, M S, Thijs, J L, and Wijk, F van
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- 2021
28. Self-reported versus ‘true’ adherence in heart failure patients: a study using the Medication Event Monitoring System
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Nieuwenhuis, M. M. W., Jaarsma, T., van Veldhuisen, D. J., and van der Wal, M. H. L.
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- 2012
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29. On the surgical treatment of hypertrophic scars: a comprehensive guideline for the surgical treatment of hypertrophic scars
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Stekelenburg, C. M., Van der Wal, M. B. A., Middelkoop, E., Niessen, F. B., and Van Zuijlen, P. P. M.
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- 2012
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30. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
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Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, Kastelein JJP, Cornel JH, Pais P, Pella D, Genest J, Cifkova R, Lorenzatti A, Forster T, Kobalava Z, Vida-Simiti L, Flather M, Shimokawa H, Ogawa H, Dellborg M, Rossi PRF, Troquay RPT, Libby P, Glynn RJ, Novo S, Krum H, Varigos J, Siostrzonek P, Sinnaeve P, Gotcheva N, Yong H, Urina-Triana M, Milicic D, Vettus R, Manolis AJ, Wyss F, Sigurdsson A, Fucili A, Veze I, Petrauskiene B, Salvador L, Klemsdal TO, Medina F, Budaj A, Otasevic P, Lainscak M, Seung KB, Commerford P, Donath M, Hwang JJ, Kultursay H, Bilazarian S, East C, Forgosh L, Harris B, Ligueros M, Bohula E, Charmarthi B, Cheng S, Chou S, Danik J, McMahon G, Maron B, Ning M, Olenchock B, Pande R, Perlstein T, Pradhan A, Rost N, Singhal A, Taqueti V, Wei N, Burris H, Cioffi A, Dalseg AM, Ghosh N, Gralow J, Mayer T, Rugo H, Fowler V, Limaye AP, Cosgrove S, Levine D, Lopes R, Scott J, Hilkert R, Tamesby G, Mickel C, Manning B, Woelcke J, Tan M, Manfreda S, Ponce T, Kam J, Saini R, Banker K, Salko T, Nandy P, Tawfik R, O’Neil G, Manne S, Jirvankar P, Lal S, Nema D, Jose J, Collins R, Bailey K, Blumenthal R, Colhoun H, Gersh B, Abreu M, Actis MV, Aiub J, Aiub F, Albisu J, Alvarisqueta A, Avalos V, Barreto M, Berli MA, Blumberg C, Bocanera M, Botta C, Bowen L, Budassi N, Buhlman S, Westberg JC, Carabajal T, Caruso G, Casala J, Cendali G, Coloma G, Berra FC, Cuneo C, Degennaro N, Dellasa M, Diaz M, Dos Santos P, Espinosa V, Facello A, Facello M, Farias E, Fernandez AA, Ferrari V, Pacora FF, Flores GS, Franco M, Gabito A, Viola HG, Garcia F, Garcia Duran R, Garcia Pinna J, Glenny J, Godoy Sanchez M, Grosse A, Guzman P, Hasbani E, Hominal M, Ibañez J, Jure H, Jure D, Vico ML, Liniado G, Luciardi H, Luquez H, Maehara G, Maffei L, Majul C, Mallagray M, Marinaro S, Martinez J, Massaccesi R, De Los Milagros Had M, Azize GM, Montana O, Montenegro E, Morell Y, Muntaner J, Navarrete S, Olmedo M, Paganini M, Paz S, Perez Manghi F, Piskorz D, Polato C, Recoaro R, Romano A, Salinger M, Sanchez A, Saravia MA, Sarjanovich R, Scaro G, Schiavi LB, Soler J, Tinnirello V, Tomassi A, Valle M, Vallejo MA, Venturini C, Marcela Wenetz LM, Yossen M, Zaidman C, Zalazar L, Zangroniz P, Amerena J, Brady L, Colquhoun D, Eccleston D, Ferreira-Jardim A, French J, Jayasinghe R, Mcintosh C, Ord M, Plotz M, Purnell P, Roberts-Thomson P, Schultz C, Shanahan T, Tan R, Taverner P, Turner F, Vibert J, Vorster M, William M, Youssef G, Bergler-Klein J, Brath H, Brodmann M, Fliesser-Goerzer E, Haider K, Heeren G, Hiden C, Mandic L, Paulweber B, Ploechl A, Prenner A, Steringer-Mascherbauer R, Strohner-Kaestenbauer H, Barbato E, Bouvy C, Briké C, Charlier F, Cools F, De Knijf K, De Wolf L, Delforge M, Deweerdt N, Gits F, Goffinet C, Hermans K, Hollanders G, Mestdagh I, Pirenne B, Servaes V, Simons N, Tahon S, Theunissen E, Van Genechten G, Vervoort G, Vissers C, Vranckx P, Vrolix M, Abib E Jr, Abrantes J, Araujo Fonseca 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A, Pagett K, Pogson A, Price R, Price D, Procter K, Pye M, Redfearn H, Rewbury J, Ryding A, Sattar N, Sharp A, Shaw P, Simpson H, Smith W, Squire I, Storey R, Teenan M, Thomas H, Townend J, Trevelyan J, Wakeling J, Walukiewicz P, Wilkinson S, Zaman A, Acevedo L, Benton J, Abbate A, Aboufakher R, Acampora M, Acampora D, Aceto L, Acevedo B, Acheatel R, Adams M, Adams A, Ahmad I, Ahmed SH, Aish B, Akyea-Djamson A, Al Joundi T, Alcide P, Alfieri A, Alfonso T, Alfrey A, Allen J, Alllison DC, Almaliky T, Amos A, Angiolillo D, Antolick A, Ara M, Aragorn L, Arevalo S, Armas E, Arthur A, Asafu-Adjaye N, Ashcom T, Ashford M, Aslam A, Ather N, Atieh M, Aull L, Ayala M, Azizad M, Backer T, Baehl S, Bailey S, Bair S, Baker C, Ballmajo M, Pieretti HB, Baquero A, Barnett S, Baron S, Bartkowiak A, Bashir K, Beall K, Beauregard LA, Sarah S, Beckett L, Belejchak P, Bendelow T, Bender D, Benjamin S, Berdoff R, Berger V, Bergeron P, Berk M, Bernstein M, Binns Y, Bitzer V, Blahey M, Bloch S, Bluemel J, Boffetti P, Boley K, Bonner J, Boudreaux R, Boulanger K, Bradley A, Bramlet D, Bredlau C, Briggs S, Brousalis L, Brown S, Brown C, Buchannan C, Burke W, Burley T, Burton C, Burtt D, Byars W, Caballero-Valiente B, Carr K, Halliwell TC, Castillo J, Cei L, Cerda L, Chambers J, Chamblee T, Chattin W, Chee L, Chen YC, Cherlin R, Cheung D, Chiodi L, Christensen L, Christenson S, Cislowski D, Clavier-Firmin C, Colfer H, Colvin T, Cosgrove N, Covert C, Cox B, Cox R, Craig W, Crandall L, Crepps K, Cromer M, Cruz H, Cruz H, Cruz M, Cucher F, Damron M, Dave K, Dave B, Davis M, Davis B, Dawkins-Hughes S, Dean J, Debnam S, Defosse C, Dehning M, Dela Llana A, Dellorso M, Denham D, Desalle D, Dettmer M, Dhawan M, Diago M, Dicken T, Diederich C, Diederich M, Diehl R, Digangi D, Diller P, Dimattia M, Dodds G, Doggett J, Donahue K, Doughty L, Dragutksy B, Dreese M, Dunhurst F, Dunn D, Dutka C, Earl J, Eaton C, Eaves W, Ebeling K, Eder F, Edgerton L, Edillo C, Edwards J, Edwards T, Einhorn D, El Hafi S, Ellis M, Erickson B, Ervin W, Eskridge L, Fail P, Falcon D, Fang C, Fattal P, Fawson A, Felix L, Ferdinand K, Fien E, Fintel D, Firek C, Fitz-Patrick D, Flores E, Flores E, Flores H, Floro T, Forker A, Foster M, Foucauld J, Lehman KF, Fox B, Francoeur L, Frandsen B, Frandsen B, Frivold G, Fruchter G, Fullerton D, Gabriel J, Gacioch G, Garas S, Garcia N, Garcia Rinaldi R, Garcia-Fragoso V, Garcia-Portela M, Gelb R, George F, Ghali J, Gilbert J, Gilley J, Glancy R, Goff R, Goldberg N, Gonzales D, Gonzales V, Gonzalez E, Gorges R, Gould R, Grabeau R, Grable M, Graham JA, Graif J, Green E, Greener R, Greenway F, Grieshaber V, Griffin S, Gros C, Gudipati RVC, Guillinta P, Gupta V, Gutmann J, Gwyn M, El Hachem M, Hage F, Hageman T, Haidar A, Hakas J, Haldis T, Hall L, Hall C, Hall S, Halpern S, Hamud-Socoro A, Hardee L, Harrell W, Harrington A, Hartwell J, Hasan F, Hattler B, Haught H, Haynes E, Haywood A, Heaney L, Hecht J, Hernandez I, Herzog W, Hess E, Hill H, Hilton T, Hinderaker P, Hodnett P, Hoffman M, Hogan C, Holmes Z, Rees DH, Hotchkiss D, Huang P, Humbert J, Hutchens E, Iachini K, Ibarra M, Igbokidi O, Ilahi T, Imbrognio M, Ipp E, Iteld B, Jacques G, Jafri A, Jafry B, Jardula M, Jefferson D, Jenkins R, Johnson E, Johnson J, Jones S, Kawahara M, Kelehan S, Kelly R, Kendall T, Kereiakes D, Khan M, Khan S, Kick J, Kimmel M, King T, King A, Kirkland S, Kissel S, Kitchens D, Klein P, Klugherz B, Korban E, Koren M, Korte M, Kostis J, Kotek L, Kozak M, Kreutter F, Kusnick B, Labovitz R, Lail J, Lamance J, Lamas G, Lambert J, Lambert C, Landzberg J, Langdon J, Lavoie W, Ledger G, Lee T, Lee K, Lehman R, Leimbach W, Lennard M, Lepor N, Lester F, Levin P, Levinson L, Lewis D, Lillo J, Link L, Long C, Longaker R, Lorch G, Lucksinger G, Lynd S, Rhudy JM, Madder R, Magness K, Maheshwari A, Alan A, Malek M, Maletz L, Malhotra V, Malhotra S, Mandviwala M, Mani CK, Manuel J, Marchelletta N, Marshall L, Marsters M, Martin L, Martinez E, Mavromatis K, Maynard R, Mays M, Mays B, Mbulaiteye A, Mcalister R, Mccoy C, Mccrary D Jr, Mccullough-O'Brien H, Mcdonald M, Mcgill J, Mcgrew F, Mckenzie C, Mclaurin B, Mclellan BA, Mcneil D, Mcneill R, Mehrle A, Melbie K, Melliza T, Messina T, Meyer R, Michel K, Mikdadi G, Miller C, Miller R, Miller A, Miller G, Miller W, Mitchell J, Moats DJR, Mody F, Moffat J, Molk B, Molter D, Monroe T, Montero H, Montgomery R, Mookherjee D, Moran J, Moriarty P, Morrison J, Morton D, Moshayedi P, Mosley J, Moustafa M, Munshi K, Murray A, Mustafa J, Nadar V, Naidu R, Nalley J, Navy S, Neil L, Neutel JM, Niblack P, Nicely V, Nicolai M, Nijmeh G, Nikas A, Nikyar A, Nixon S, Norman L, Noto G, Nour K, Nugent A, Ocman B, Odegard A, Olsen S, Ortiz-Carrasquillo R, Ossino N, Paez H, Palchick B, Paliwal Y, Pannell R, Parfait V, Partridge J, Patel B, Patel R, Patel M, Patel S, Paysor C, Pena A, Pereira S, Perez M, Perez A, Perkins H, Perry B, Peters P, Phillippi C, Phillips A, Phillips A, Piacente R, Pintado M, Pish R, Pitt W, Poling T, Pomposini D, Poock J, Potts J, Poudrier R, Prior J, Pritchard C, Purighalla R, Quddusi K, Quinones J, Quinton D, Radin M, Radojcsics B, Rajput B, Rama B, Ramos M, Rauch R, Raynes K, Reber AM, Reddy J, Reeves M, Reilly K, Renaud K, Resnick H, Reyes R, Richardson M, Riethof M, Riser J, Rodero M, Rodriguez Araya E, Roper L, Rozeman P, Ruder D, Runquist L, Sack G, Saint-Jacques H, Salfity M, Sall N, Sam K, Samal A, Sanchez D, Santiago J Jr, Savignano C, Saylor R, Scheffel M, Schifferdecker B, Schindler E, Schneider P, Schneider R, Schnitzler R, Schrager B, Schwartz A, Scott R, Seals A, Shah AV, Shah A, Shatsky K, Shayani S, Shealy N, Sheets L, Shelley J, Shepard P, Shetty S, Silver K, Simon M, Singh K, Singh N, Sizemore BC, Skatrud L, Slayton C, Slimak V, Sloane G, Smallwood B, Smith P, Smith M, Smith T, Smith G, Smith B, Smith W, Smith M, Smith J, Smith J, Soca Y, Sofley C, Sopko K, Sosa-Padilla M, Sotolongo R, Sprinkle B, Srivastava S, Starzec M, Steinhoff J, Stelly L, Stinson J, Stoddard M, Stoltz S, Stone B, Stover T, Strain J, Strugatsky S, Stys T, Suleman A, Sullivan P, Tamez W, Tandon N, Teltser M, Terry PS, Terry K, Tessmar C, Thekkoott D, Thomas D, Thomas DM, Thompson E, Thompson J, Thornton A, Tjaden T, Tobias C, Topper J, Tran A, Treasure C, Trenkamp P, Trevino M, Tsou L, Tuholske C, Uy W, Vahtel M, Vaid B, Valenzuela M, Vance A, Vandam J, Vanhecke T, Vanness WC III, Vargas R, Vaz S, Vazquez Tanus J, Veerina K, Vega J, Vento A, Vijay N, Voelker F, Vogt E, Vold D, Vora K, Wade RD, Wadell C, Waksman R, Walker K, Walker K, Wallace K, Warren M, Washam M, Watson B, Webel R, Wells T, West M, Whitaker J, White J, White C, White A, White A, Wilhoit G, Wilkins M, Willingham K, Wilson S, Wilson V, Wise J, Woodall S, Woods A, Wright J, Wu J, Xu ZJ, Yarows S, Young A, Younis L, Zarate J, Zebrack J, Zhang W, Zieve F, Zineldine A, Ridker, P. M., Everett, B. M., Thuren, T., Macfadyen, J. G., Chang, W. H., Ballantyne, C., FONSECA E PIRES, CARLOS EDUARDO, Nicolau, J., Koenig, W., Anker, S. D., Kastelein, J. J. P., Cornel, J. H., Pais, P., Pella, D., Genest, J., Cifkova, R., Lorenzatti, A., Forster, T., Kobalava, Z., Vida-Simiti, L., Flather, M., Shimokawa, H., Ogawa, H., Dellborg, M., Rossi, P. R. F., Troquay, R. P. T., Libby, P., Glynn R., J, CANTOS Trial, Group, Perrone, Filardi, P, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, ACS - Pulmonary hypertension & thrombosis, and ACS - Atherosclerosis & ischemic syndromes
- Subjects
0301 basic medicine ,030204 cardiovascular system & hematology ,law.invention ,0302 clinical medicine ,c-reactive protein ,Randomized controlled trial ,law ,Cardiovascular Disease ,middle aged ,double-blind method ,antibodies ,Myocardial infarction ,humans ,Stroke ,interleukin-1beta ,biology ,Antibodies, Monoclonal ,drug ,General Medicine ,Lipid ,Aged ,anti-inflammatory agents ,monoclonal ,humanized ,atherosclerosis ,cardiovascular diseases ,dose-response relationship ,female ,incidence ,infections ,lipids ,male ,myocardial infarction ,neutropenia ,secondary prevention ,stroke ,Anti-Inflammatory Agent ,aged ,Editorial ,Atherosclerosi ,Monoclonal ,Human ,medicine.drug ,medicine.medical_specialty ,Neutropenia ,Antibodies, Monoclonal, Humanized ,Infections ,Placebo ,antibodies, monoclonal ,dose-response relationship, drug ,infection ,medicine (all) ,03 medical and health sciences ,Internal medicine ,medicine ,Dose-Response Relationship, Drug ,business.industry ,Antiinflammatory Therapy, Canakinumab, for Atherosclerotic Disease ,C-reactive protein ,medicine.disease ,Surgery ,Canakinumab ,030104 developmental biology ,biology.protein ,business - Abstract
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.)
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- 2017
31. Optimizing a communication tool to improve discussion about the heart failure trajectory in Sweden and the Netherlands
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Hjelmfors, L., Stromberg, A., Friedrichsen, M., Sandgren, A., Mårtensson, Jan, Jaarsma, T., Van der Wal, M. H. L., Hjelmfors, L., Stromberg, A., Friedrichsen, M., Sandgren, A., Mårtensson, Jan, Jaarsma, T., and Van der Wal, M. H. L.
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- 2020
32. Acceptability of a communication tool on the heart failure trajectory : data from Sweden and the Netherlands
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Van der Wal, M. H. L., Stromberg, A., Milberg, A., Mårtensson, Jan, Sandgren, A., Friedrichsen, M., Hjelmfors, L., Jaarsma, T., Van der Wal, M. H. L., Stromberg, A., Milberg, A., Mårtensson, Jan, Sandgren, A., Friedrichsen, M., Hjelmfors, L., and Jaarsma, T.
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- 2020
33. Optimizing of a question prompt list to improve communication about the heart failure trajectory in patients, families, and health care professionals
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Hjelmfors, L., van der Wal, M. H. L., Friedrichsen, M., Milberg, A., Mårtensson, Jan, Sandgren, A., Strömberg, A., Jaarsma, T., Hjelmfors, L., van der Wal, M. H. L., Friedrichsen, M., Milberg, A., Mårtensson, Jan, Sandgren, A., Strömberg, A., and Jaarsma, T.
- Abstract
Background: The aim of this study was to optimize a Question Prompt List which is designed to improve communication about the heart failure trajectory among patients, family members, and health care professionals. Methods: Data were collected in a two-round Delphi survey and a cross-sectional survey, including patients with heart failure, their family members, and health care professionals working in heart failure care in Sweden and the Netherlands. Acceptability for and demand of the Question Prompt List were assessed. Results: A total of 96 patients, 63 family members and 26 health care professionals participated in the study. Regarding acceptability, most of the original questions were found to be relevant by the participants for inclusion in the Question Prompt List but some cultural differences exist, which resulted in two versions of the list: a Swedish version including 33 questions and a Dutch version including 38 questions. Concerning demand, participants reported that they were interested in discussing the questions in the revised Question Prompt List with a physician or a nurse. Few patients and family members reported that they were worried by the questions in the Question Prompt List and hence did not want to discuss the questions. Conclusions: This Question Prompt List has successfully been adapted into a Swedish version and a Dutch version and includes questions about the HF trajectory which patients, their families, and health care professionals perceived to be relevant for discussion in clinical practice. Overall, patients and family members were not worried about the content in the Question Prompt List and if used in accordance with patients’ and family members’ preferences, the Question Prompt List can help to improve communication about the heart failure trajectory.
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- 2020
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34. Prognosis in heart failure; patients own perceptions: 210
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Van Der Wal, M HL., Stromberg, A., and Jaarsma, T.
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- 2013
35. CHILDHOOD BODY COMPOSITION AND GLUCOSE BALANCE: THE ROLE OF FAMILIAL PREDICPOSITION TO DIABETES AND MOTHERʼS PRE-PREGNANCY BMI: 944 accepted poster
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Vrijkotte, T., Twickler, M., van der Wal, M., and Stronks, K.
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- 2012
36. Circumstances of dying in hospitalized children
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van der Wal, M. E., Renfurm, L. N., van Vught, A. J., and Gemke, R. J. B. J.
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- 1999
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37. Rotavirusinfectie
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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38. Cyanotische aangeboren hartafwijkingen
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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39. Attention-Deficit Hyperactivity Disorder -adhd
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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40. Schisis
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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41. Anorexia nervosa, boulimia nervosa en binge eating (eetbuistoornis)
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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42. Acyanotische aangeboren hartafwijkingen
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van den Berg, H., primary, de Jong-van der Wal, M. A., additional, and Beeldman-Brinkman, C. C. C., additional
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- 2008
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43. Epilepsie bij kinderen
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van Hemert-van der Poel, J. C., primary, Beeldman-Brinkman, C. C. C., additional, and de Jong-van der Wal, M. A., additional
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- 2008
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44. Promoting physical activity in children: the stepwise development of the primary school-based JUMP-in intervention applying the RE-AIM evaluation framework
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De Meij, J S B, Chinapaw, M J M, Kremers, S P J, Van der wal, M F, Jurg, M E, and Van Mechelen, W
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- 2010
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45. Multifunctional river Groynes
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Abe, Shuya, primary, Yasuharu Watanabe, Dr, additional, Bauer, Christian, additional, Röttcher, Klaus, additional, Tönsmann, Frank, additional, Bettmann, T, additional, Webler, H, additional, Nijland, H, additional, Eerden, H, additional, Betts, H, additional, Joy, C, additional, Haslam, W, additional, Hallam, A, additional, Xingping, Jin, additional, Bose, Shivashish, additional, Ahmed Choudhury, Giasuddin, additional, Couderé, K, additional, Gommers, A, additional, Dauwe, W, additional, Flikweert, J, additional, Blommaar, P, additional, van Gerven, K, additional, Akkerman, G, additional, Akkerman, P, additional, Gudkov, D, additional, Derevets, V, additional, Kireev, S, additional, Nazarov, A, additional, Harries, T, additional, Tapsell, S, additional, Havinga, H, additional, Roovers, G, additional, Stamm, J, additional, Fischenich, C, additional, Khan, A, additional, Kreibich, H, additional, Thieken, A, additional, Merz, B, additional, Müller, M, additional, Li, Kungang, additional, van Linn, A, additional, Köngeter, J, additional, Majewski, W, additional, Jasinska, E, additional, Masumoto, T, additional, Hai, Pham, additional, Shimizu, K, additional, Niemeyer, M, additional, Schaap, G, additional, Ogunyoye, F, additional, Bray, R, additional, Gunasekara, R, additional, Vigor, M, additional, Pichel, G, additional, Jost, C, additional, Rouas, G, additional, van Schijndel, S, additional, Jagers, H, additional, Mosselman, E, additional, Schropp, M, additional, Savin, A, additional, Stere, C, additional, Kersting, N, additional, Waals*, J, additional, Kool, H, additional, Van Zutven, B, additional, van der Wal, M, additional, and Stam, J, additional
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- 2006
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46. Maternal pre-pregnancy body mass index explains infant’s weight and BMI at 14 months: results from a multi-ethnic birth cohort study
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Mesman, I, Roseboom, T J, Bonsel, G J, Gemke, R J, van der Wal, M F, and Vrijkotte, T G M
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- 2009
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47. Groyne optimisation and river hydrodynamics
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Akkerman, G, primary, van Heereveld, M, additional, van der Wal, M, additional, and Stam, J, additional
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- 2004
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48. Ethnic differences in preterm birth and its subtypes: the effect of a cumulative risk profile
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Goedhart, G, van Eijsden, M, van der Wal, M F, and Bonsel, G J
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- 2008
49. Is psychosocial stress in first ongoing pregnancies associated with pre-eclampsia and gestational hypertension?
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Vollebregt, K C, van der Wal, M F, Wolf, H, Vrijkotte, T GM, Boer, K, and Bonsel, G J
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- 2008
50. Late start of antenatal care among ethnic minorities in a large cohort of pregnant women
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Alderliesten, M E, Vrijkotte, T GM, van der Wal, M F, and Bonsel, G J
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- 2007
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