50 results on '"van der Velden, Walter J.F.M."'
Search Results
2. Posaconazole bioavailability of the solid oral tablet is reduced during severe intestinal mucositis
- Author
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Jansen, Anouk M.E., Muilwijk, Eline W., van der Velden, Walter J.F.M., Maertens, Johan A., Aerts, Robina, Colbers, Angela, Burger, David, Verweij, Paul E., ter Heine, Rob, Blijlevens, Nicole M.A., and Brüggemann, Roger J.M.
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- 2022
- Full Text
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3. Clofarabine added to intensive treatment in adult patients with newly diagnosed ALL: the HOVON-100 trial
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Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjen A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, Halkes, Constantijn J.M., Fijnheer, Rob, Havelange, Violaine, van Sluis, Geerte L., Legdeur, Marie-Cecile, Deeren, Dries, Gadisseur, Alain, Sinnige, Harm A.M., Breems, Dimitri A., Jaspers, Aurélie, Legrand, Ollivier, Terpstra, Wim E., Boersma, Rinske S., Mazure, Dominiek, Triffet, Agnes, Tick, Lidwine W., Beel, Karolien, Maertens, Johan A., Beverloo, H. Berna, Bakkus, Marleen, Homburg, Christa H.E., de Haas, Valerie, van der Velden, Vincent H.J., and Cornelissen, Jan J.
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- 2022
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4. Decitabine in Older Patients with AML: Quality of Life Results of the EORTC-GIMEMA-GMDS-SG Randomized Phase III Trial
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Efficace, Fabio, primary, Kicinski, Michal, additional, Coens, Corneel, additional, Suciu, Stefan, additional, van der Velden, Walter J.F.M, additional, Noppeney, Richard, additional, Chantepie, Sylvain P, additional, Griskevicius, Laimonas, additional, Neubauer, Andreas, additional, Audisio, Ernesta, additional, Luppi, Mario, additional, Fuhrmann, Stephan, additional, Foà, Robin, additional, Crysandt, Martina, additional, Gaidano, Gianluca, additional, Vrhovac, Radovan, additional, Venditti, Adriano, additional, Posthuma, Eduardus F.M., additional, Candoni, Anna, additional, Baron, Frédéric, additional, Legrand, Olivier, additional, Mengarelli, Andrea, additional, Fazi, Paola, additional, Vignetti, Marco, additional, Giraut, Anne, additional, Wijermans, Pierre W., additional, Huls, Gerwin A, additional, and Lübbert, Michael, additional
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- 2024
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5. Pretransplantation MRD in Older Patients With AML After Treatment With Decitabine or Conventional Chemotherapy
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Hilberink, Jacobien R., Morsink, Linde M., van der Velden, Walter J.F.M, Mulder, André B., Hazenberg, Carin L.E, de Groot, Marco, Choi, Goda, Schuringa, Jan Jacob, Meijer, Kees, Blijlevens, Nicole M.A., Ammatuna, Emanuele, and Huls, Gerwin
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- 2021
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6. Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial
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Löwenberg, Bob, Pabst, Thomas, Maertens, Johan, Gradowska, Patrycja, Biemond, Bart J., Spertini, Olivier, Vellenga, Edo, Griskevicius, Laimonas, Tick, Lidwine W., Jongen-Lavrencic, Mojca, van Marwijk Kooy, Marinus, Vekemans, Marie-Christiane, van der Velden, Walter J.F.M., Beverloo, Berna, Michaux, Lucienne, Graux, Carlos, Deeren, Dries, de Weerdt, Okke, van Esser, Joost W.J., Bargetzi, Mario, Klein, Saskia K., Gadisseur, Alain, Westerweel, Peter E., Veelken, Hendrik, Gregor, Michael, Silzle, Tobias, van Lammeren-Venema, Daniëlle, Moors, Ine, Breems, Dimitri A., Hoogendoorn, Mels, Legdeur, Marie-Cecile J.C., Fischer, Thomas, Kuball, Juergen, Cornelissen, Jan, Porkka, Kimmo, Juliusson, Gunnar, Meyer, Peter, Höglund, Martin, Gjertsen, Bjorn T., Janssen, Jeroen J.W.M., Huls, Gerwin, Passweg, Jakob, Cloos, Jacqueline, Valk, Peter J.M., van Elssen, Catharina H.M.J., Manz, Markus G., Floisand, Yngvar, and Ossenkoppele, Gert J.
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- 2021
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7. Benefits and risks of clofarabine in adult acute lymphoblastic leukemia investigated in depth by multi-state modeling
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MS Hematologie, Cancer, Infection & Immunity, Hermans, Sjoerd J.F., van Norden, Yvette, Versluis, Jurjen, Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjan A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, van der Velden, Vincent H.J., de Wreede, Liesbeth C., Postmus, Douwe, Pignatti, Francesco, Cornelissen, Jan J., MS Hematologie, Cancer, Infection & Immunity, Hermans, Sjoerd J.F., van Norden, Yvette, Versluis, Jurjen, Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjan A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, van der Velden, Vincent H.J., de Wreede, Liesbeth C., Postmus, Douwe, Pignatti, Francesco, and Cornelissen, Jan J.
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- 2024
8. Benefits and risks of clofarabine in adult acute lymphoblastic leukemia investigated in depth by multi-state modeling
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Hermans, Sjoerd J.F., van Norden, Yvette, Versluis, Jurjen, Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjan A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, van der Velden, Vincent H.J., de Wreede, Liesbeth C., Postmus, Douwe, Pignatti, Francesco, Cornelissen, Jan J., Hermans, Sjoerd J.F., van Norden, Yvette, Versluis, Jurjen, Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjan A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, van der Velden, Vincent H.J., de Wreede, Liesbeth C., Postmus, Douwe, Pignatti, Francesco, and Cornelissen, Jan J.
- Abstract
Background: We recently reported results of the prospective, open-label HOVON-100 trial in 334 adult patients with acute lymphoblastic leukemia (ALL) randomized to first-line treatment with or without clofarabine (CLO). No improvement of event-free survival (EFS) was observed, while a higher proportion of patients receiving CLO obtained minimal residual disease (MRD) negativity. Aim: In order to investigate the effects of CLO in more depth, two multi-state models were developed to identify why CLO did not show a long-term survival benefit despite more MRD-negativity. Methods: The first model evaluated the effect of CLO on going off-protocol (not due to refractory disease/relapse, completion or death) as a proxy of severe treatment-related toxicity, while the second model evaluated the effect of CLO on obtaining MRD negativity. The subsequent impact of these intermediate events on death or relapsed/refractory disease was assessed in both models. Results: Overall, patients receiving CLO went off-protocol more frequently than control patients (35/168 [21%] vs. 18/166 [11%], p = 0.019; HR 2.00 [1.13–3.52], p = 0.02), especially during maintenance (13/44 [30%] vs. 6/56 [11%]; HR 2.85 [95%CI 1.08–7.50], p = 0.035). Going off-protocol was, however, not associated with more relapse or death. Patients in the CLO arm showed a trend towards an increased rate of MRD-negativity compared with control patients (HR MRD-negativity: 1.35 [0.95–1.91], p = 0.10), which did not translate into a significant survival benefit. Conclusion: We conclude that the intermediate states, i.e., going off-protocol and MRD-negativity, were affected by adding CLO, but these transitions were not associated with subsequent survival estimates, suggesting relatively modest antileukemic activity in ALL.
- Published
- 2024
9. Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation
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Sommer, Sebastian, Cruijsen, Marjan, Claus, Rainer, Bertz, Hartmut, Wäsch, Ralph, Marks, Reinhard, Zeiser, Robert, Bogatyreva, Lioudmila, Blijlevens, Nicole M.A., May, Annette, Duyster, Justus, Huls, Gerwin, van der Velden, Walter J.F.M., Finke, Jürgen, and Lübbert, Michael
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- 2018
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10. Targeting the interleukin-1 pathway in patients with hematological disorders
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de Mooij, Charlotte E.M., Netea, Mihai G., van der Velden, Walter J.F.M., and Blijlevens, Nicole M.A.
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- 2017
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11. Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia
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van Baarle, Floor L.F., primary, van de Weerdt, Emma K., additional, van der Velden, Walter J.F.M., additional, Ruiterkamp, Roelof A., additional, Tuinman, Pieter R., additional, Ypma, Paula F., additional, van den Bergh, Walter M., additional, Demandt, Astrid M.P., additional, Kerver, Emile D., additional, Jansen, A.J. Gerard, additional, Westerweel, Peter E., additional, Arbous, Sesmu M., additional, Determann, Rogier M., additional, van Mook, Walther N.K.A., additional, Koeman, Mirelle, additional, Mäkelburg, Anja B.U., additional, van Lienden, Krijn P., additional, Binnekade, Jan M., additional, Biemond, Bart J., additional, and Vlaar, Alexander P.J., additional
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- 2023
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12. Predictors of the corrected count increment after platelet transfusion, a secondary analysis of the PACER randomized controlled trial
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van Baarle, Floor L.F., van de Weerdt, Emma K., van der Velden, Walter J.F.M., Ruiterkamp, Roelof A., Tuinman, Pieter R., Ypma, Paula F., van den Bergh, Walter M., Demandt, Astrid M.P., Kerver, Emile D., Jansen, A. J.Gerard, Westerweel, Peter E., Arbous, M. Sesmu, Determann, Rogier M., van Mook, Walther N.K.A., Koeman, Mirelle, Mäkelburg, Anja B.U., van Lienden, Krijn P., Vlaar, Alexander P.J., Biemond, Bart J., van Baarle, Floor L.F., van de Weerdt, Emma K., van der Velden, Walter J.F.M., Ruiterkamp, Roelof A., Tuinman, Pieter R., Ypma, Paula F., van den Bergh, Walter M., Demandt, Astrid M.P., Kerver, Emile D., Jansen, A. J.Gerard, Westerweel, Peter E., Arbous, M. Sesmu, Determann, Rogier M., van Mook, Walther N.K.A., Koeman, Mirelle, Mäkelburg, Anja B.U., van Lienden, Krijn P., Vlaar, Alexander P.J., and Biemond, Bart J.
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- 2023
13. Addition of 10-Day Decitabine to Fludarabine/Total Body Irradiation Conditioning is Feasible and Induces Tumor-Associated Antigen-Specific T Cell Responses
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Cruijsen, Marjan, Hobo, Willemijn, van der Velden, Walter J.F.M., Bremmers, Manita E.J., Woestenenk, Rob, Bär, Brigitte, Falkenburg, J.H. Frederik, Kester, Michel, Schaap, Nicolaas P.M., Jansen, Joop, Blijlevens, Nicole N.M., Dolstra, Harry, and Huls, Gerwin
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- 2016
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14. A difficult to treat Leishmania infantum relapse after allogeneic stem cell transplantation
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Arts, Rob J.W., primary, Ector, Geneviève I.C.G., additional, Bosch-Nicolau, Pau, additional, Molina, Isreal, additional, McCall, Matthew B.B., additional, van der Velden, Walter J.F.M., additional, van Laarhoven, Arjan, additional, de Mast, Quirijn, additional, and van Dorp, Suzanne, additional
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- 2023
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15. The HOVON 100 Study in Adult Acute Lymphoblastic Leukemia Re-Analysed By Multi-State Modeling: Benefits and Risks of Clofarabine
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Hermans, Sjoerd J.F., primary, Norden, Yvette, additional, Versluis, Jurjen, additional, Rijneveld, Anita W., additional, De Weerdt, Okke, additional, Biemond, Bart J., additional, van de Loosdrecht, Arjan A., additional, Van der Wagen, Lotte E., additional, Bellido, Mar, additional, Van Gelder, Michel, additional, Van der Velden, Walter J.F.M., additional, Selleslag, Dominik, additional, van Lammeren, Danielle, additional, van der Velden, Vincent H.J., additional, de Wreede, Liesbeth C., additional, Postmus, Douwe, additional, Pignatti, Francesco, additional, and Cornelissen, Jan J., additional
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- 2022
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16. Targeting the IL17 Pathway for the Prevention of Graft-Versus-Host Disease
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van der Waart, Anniek B., van der Velden, Walter J.F.M., Blijlevens, Nicole M., and Dolstra, Harry
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- 2014
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17. Association of Disparities in Known Minor Histocompatibility Antigens with Relapse-Free Survival and Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation
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Hobo, Willemijn, Broen, Kelly, van der Velden, Walter J.F.M., Greupink-Draaisma, Annelies, Adisty, Niken, Wouters, Yannick, Kester, Michel, Fredrix, Hanny, Jansen, Joop H., van der Reijden, Bert, Falkenburg, J.H. Frederik, de Witte, Theo, Preijers, Frank, Schattenberg, Ton, Feuth, Ton, Blijlevens, Nicole M., Schaap, Nicolaas, and Dolstra, Harry
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- 2013
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18. Clofarabine added to intensive treatment in adult patients with newly diagnosed ALL:the HOVON-100 trial
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Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjen A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Danie€lle, Halkes, Constantijn J.M., Fijnheer, Rob, Havelange, Violaine, van Sluis, Geerte L., Legdeur, Marie Cecile, Deeren, Dries, Gadisseur, Alain, Sinnige, Harm A.M., Breems, Dimitri A., Jaspers, Aurelie, Legrand, Ollivier, Terpstra, Wim E., Boersma, Rinske S., Mazure, Dominiek, Triffet, Agnes, Tick, Lidwine W., Beel, Karolien, Maertens, Johan A., Beverloo, H. Berna, Bakkus, Marleen, Homburg, Christa H.E., de Haas, Valerie, van der Velden, Vincent H.J., Cornelissen, Jan J., Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjen A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Danie€lle, Halkes, Constantijn J.M., Fijnheer, Rob, Havelange, Violaine, van Sluis, Geerte L., Legdeur, Marie Cecile, Deeren, Dries, Gadisseur, Alain, Sinnige, Harm A.M., Breems, Dimitri A., Jaspers, Aurelie, Legrand, Ollivier, Terpstra, Wim E., Boersma, Rinske S., Mazure, Dominiek, Triffet, Agnes, Tick, Lidwine W., Beel, Karolien, Maertens, Johan A., Beverloo, H. Berna, Bakkus, Marleen, Homburg, Christa H.E., de Haas, Valerie, van der Velden, Vincent H.J., and Cornelissen, Jan J.
- Abstract
Clofarabine (CLO) is a nucleoside analog with efficacy in relapsed/refractory acute lymphoblastic leukemia (ALL). This randomized phase 3 study aimed to evaluate whether CLO added to induction and whether consolidation would improve outcome in adults with newly diagnosed ALL. Treatment of younger (18-40 years) patients consisted of a pediatric-inspired protocol, and for older patients (41-70 years), a semi-intensive protocol was used. Three hundred and forty patients were randomized. After a median follow-up of 70 months, 5-year event-free survival (EFS) was 50% and 53% for arm A and B (CLO arm). For patients #40 years, EFS was 58% vs 65% in arm A vs B, whereas in patients .40 years, EFS was 43% in both arms. Complete remission (CR) rate was 89% in both arms and similar in younger and older patients. Minimal residual disease (MRD) was assessed in 200 patients (60%). Fifty-four of 76 evaluable patients (71%) were MRD2 after consolidation 1 in arm A vs 75/81 (93%) in arm B (P 5 .001). Seventy (42%) patients proceeded to allogeneic hematopoietic stem cell transplantation in both arms. Five-year overall survival (OS) was similar in both arms: 60% vs 61%. Among patients achieving CR, relapse rates were 28% and 24%, and nonrelapse mortality was 16% vs 17% after CR. CLO-treated patients experienced more serious adverse events, more infections, and more often went off protocol. This was most pronounced in older patients. We conclude that, despite a higher rate of MRD negativity, addition of CLO does not improve outcome in adults with ALL, which might be due to increased toxicity.
- Published
- 2022
19. Polymorphisms in CCR6 Are Associated with Chronic Graft-versus-Host Disease and Invasive Fungal Disease in Matched-Related Hematopoietic Stem Cell Transplantation
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Broen, Kelly, van der Waart, Anniek B., Greupink-Draaisma, Annelies, Metzig, Julia, Feuth, Ton, Schaap, Nicolaas P.M., Blijlevens, Nicole M.A., van der Velden, Walter J.F.M., and Dolstra, Harry
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- 2011
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20. Infections in the Immunocompromised Host
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Donnelly, J. Peter, primary, Blijlevens, Nicole M.A., additional, and van der Velden, Walter J.F.M., additional
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- 2015
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21. Contributors
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Aagaard, Kjersti, primary, Abrahamian, Fredrick M., additional, Allos, Ban Mishu, additional, Andes, David R., additional, Aoki, Fred Y., additional, Apicella, Michael A., additional, Ard, Kevin L., additional, Arias, Cesar A., additional, Aronoff, David M., additional, Augenbraun, Michael H., additional, Averhoff, Francisco, additional, Azar, Dimitri T., additional, Baddour, Larry M., additional, Baden, Lindsey R., additional, Baker, Carol J., additional, Ballard, Ronald C., additional, Barber, Gerard R., additional, Barnes, Scott D., additional, Barouch, Dan H., additional, Barrett, Alan D., additional, Barshak, Miriam Baron, additional, Basavaraju, Sridhar V., additional, Batteiger, Byron E., additional, Baum, Stephen G., additional, Bayer, Arnold S., additional, Beckham, J. David, additional, Beekmann, Susan E., additional, Bell, Beth P., additional, Bennett, John E., additional, Bente, Dennis A., additional, Berbari, Elie F., additional, Berman, Jonathan, additional, Bertino, Joseph S., additional, Bhimraj, Adarsh, additional, Birdsall, Holly H., additional, Bisno, Alan L., additional, Blackburn, Brian G., additional, Blanton, Lucas S., additional, Blaser, Martin J., additional, Bleck, Thomas P., additional, Blijlevens, Nicole M.A., additional, Bobak, David A., additional, Bonnez, William, additional, Boothroyd, John C., additional, Borio, Luciana L., additional, Bosque, Patrick J., additional, Bower, John, additional, Bradsher, Robert W., additional, Brook, Itzhak, additional, Brown, Kevin E., additional, Brown, Patricia D., additional, Brown-Elliott, Barbara A., additional, Bruhn, Roberta L., additional, Bryant, Amy E., additional, Burd, Eileen M., additional, Burns, Jane C., additional, Bush, Larry M., additional, Calderwood, Stephen B., additional, Cano, Luz Elena, additional, Carpenter, Charles C.J., additional, Caserta, Mary T., additional, Castagnola, Elio, additional, Chaisson, Richard E., additional, Chambers, Henry F., additional, Chapman, Stephen J., additional, Chappell, James D., additional, Chen, Lea Ann, additional, Chen, Sharon C-A, additional, Chow, Anthony W., additional, Clark, Rebecca A., additional, Cohen, Jeffrey I., additional, Cohen, Myron S., additional, Cohen-Poradosu, Ronit, additional, Cohn, Susan E., additional, Connors, Mark, additional, Corey, Lawrence, additional, Cottrell, Mackenzie L., additional, Cover, Timothy L., additional, Cox, Heather L., additional, Craig, William A., additional, Crossley, Kent B., additional, Crumpacker, Clyde S., additional, Curran, James W., additional, Currie, Bart J., additional, D'Agata, Erika, additional, Damon, Inger K., additional, Darouiche, Rabih O., additional, DeBiasi, Roberta L., additional, Deepe, George S., additional, del Rio, Carlos, additional, Delemos, Andrew S., additional, DeLeo, Frank R., additional, DeMuri, Gregory P., additional, Densen, Peter, additional, Dermody, Terence S., additional, Dewar, Robin, additional, Diaz, James H., additional, Dieffenbach, Carl W., additional, Dienstag, Jules L., additional, Doi, Yohei, additional, Dolin, Raphael, additional, Donnelly, J. Peter, additional, Donnenberg, Michael S., additional, Donowitz, Gerald R., additional, Dormitzer, Philip R., additional, Drake, James M., additional, Dumler, J. Stephen, additional, Dummer, J. Stephen, additional, DuPont, Herbert L., additional, Durack, David T., additional, Durand, Marlene L., additional, Edelstein, Paul H., additional, Edmond, Michael B., additional, Edwards, John E., additional, Edwards, Morven S., additional, Eliopoulos, George M., additional, Ellison, Richard T., additional, Endy, Timothy P., additional, Engleberg, N. Cary, additional, Erdem, Hakan, additional, Ernst, Joel D., additional, Ernst, Peter B., additional, Fairhurst, Rick M., additional, Fairley, Jessica K., additional, Falkow, Stanley, additional, Falsey, Ann R., additional, Fauci, Anthony S., additional, Fekete, Thomas, additional, Fey, Paul D., additional, Fine, Steven M., additional, Fitzgerald, Daniel W., additional, Flores, Anthony R., additional, Forster, Derek, additional, Fowler, Vance G., additional, Freedman, David O., additional, Friedlander, Arthur M., additional, Galgiani, John N., additional, Gallin, John I., additional, Gallo, Robert C., additional, Gandhi, Tejal N., additional, Garrett, Wendy S., additional, Gaydos, Charlotte A., additional, Geisbert, Thomas W., additional, Gelfand, Jeffrey A., additional, Gelone, Steven P., additional, Gerding, Dale N., additional, Gershon, Anne A., additional, Gilsdorf, Janet R., additional, Goldstein, Ellie J.C., additional, Gordin, Fred M., additional, Graman, Paul S., additional, Grayson, M. Lindsay, additional, Greene, Jeffrey Bruce, additional, Griffin, Patricia M., additional, Griffith, David E., additional, Guerrant, Richard L., additional, Gul, H. Cem, additional, Haake, David A., additional, Haas, David W., additional, Haines, Charles, additional, Hall, Caroline Breese, additional, Hallak, Joelle, additional, Halperin, Scott A., additional, Hammerschlag, Margaret R., additional, Haque, Rashidul, additional, Harris, Jason B., additional, Hawkins, Claudia, additional, Hay, Roderick J., additional, Hedberg, Craig W., additional, Henderson, David K., additional, Henderson, Donald A., additional, High, Kevin P., additional, Hill, Adrian V.S., additional, Hill, David R., additional, Hinman, Alan R., additional, Hirsch, Martin S., additional, Hodowanec, Aimee, additional, Hohl, Tobias M., additional, Holland, Steven M., additional, Holzman, Robert S., additional, Hook, Edward W., additional, Hooper, David C., additional, Hooton, Thomas M., additional, Horowitz, Harold W., additional, Horsburgh, C. Robert, additional, Horton, James M., additional, Hospenthal, Duane R., additional, Hsueh, Kevin, additional, Hughes, James M., additional, Hynes, Noreen A., additional, Iovine, Nicole M., additional, Iredell, Jonathan R., additional, Ison, Michael G., additional, Janda, J. Michael, additional, Janoff, Edward N., additional, Johannsen, Eric C., additional, Kashuba, Angela D.M., additional, Kasper, Dennis L., additional, Kaye, Donald, additional, Kaye, Keith S., additional, Kaye, Kenneth M., additional, Kazura, James W., additional, Keystone, Jay S., additional, Khabbaz, Rima, additional, Khan, David A., additional, Khudyakov, Yury, additional, Kim, Rose, additional, King, Charles H., additional, Kirchhoff, Louis V., additional, Klein, Jerome O., additional, Klompas, Michael, additional, Knoll, Bettina M., additional, Knowlton, Kirk U., additional, Koehler, Jane E., additional, Kohlhoff, Stephan A., additional, Könönen, Eija, additional, Kontoyiannis, Dimitrios P., additional, Koralnik, Igor J., additional, Korpe, Poonum S., additional, Koshy, Anita A., additional, Kovacs, Joseph A., additional, Kozarsky, Phyllis, additional, Krieger, John, additional, Kroger, Andrew T., additional, Kuehnert, Matthew J., additional, Kumar, Nalin M., additional, Kuruvilla, Merin Elizabeth, additional, LaRocque, Regina C., additional, Leggett, James E., additional, Legido-Quigley, Helena, additional, Levett, Paul N., additional, Levine, Donald P., additional, Levison, Matthew E., additional, Levitt, Alexandra, additional, Lewis, Russell E., additional, Liles, W. Conrad, additional, Lima, Aldo A.M., additional, Limaye, Ajit P., additional, Lipkin, W. Ian, additional, Litman, Nathan, additional, Lorber, Bennett, additional, Luna, Ruth Ann, additional, MacDougall, Conan, additional, Roy, Rob, additional, Mackowiak, Philip A., additional, Madoff, Lawrence C., additional, Magill, Alan J., additional, Maguire, James H., additional, Maldarelli, Frank, additional, Markoff, Lewis, additional, Marrazzo, Jeanne M., additional, Marrie, Thomas J., additional, Marth, Thomas, additional, Martin, David H., additional, Martin, Gregory J., additional, Marty, Francisco M., additional, Maslow, Melanie Jane, additional, Masur, Henry, additional, Mawle, Alison, additional, Mayer, Kenneth H., additional, McBride, John T., additional, McCarthy, James S., additional, McCormack, William M., additional, McGowan, Catherine C., additional, McIntosh, Kenneth, additional, Mead, Paul S., additional, Mikulska, Malgorzata, additional, Miller, Robert F., additional, Miller, Samuel I., additional, Mitchell, David H., additional, Modlin, John F., additional, Mody, Rajal K., additional, Moellering, Robert C., additional, Moffa, Matthew, additional, Moir, Susan, additional, Montoya, José G., additional, Moore, Thomas A., additional, Moreillon, Philippe, additional, Morris, J. Glenn, additional, Morse, Caryn Gee, additional, Moseley, Robin, additional, Munford, Robert S., additional, Murphy, Edward L., additional, Murphy, Timothy F., additional, Murray, Barbara E., additional, Murray, Clinton K., additional, Murray, Patrick R., additional, Musher, Daniel M., additional, Nagel, Jerod L., additional, Nannini, Esteban C., additional, Narezkina, Anna, additional, Nash, Theodore E., additional, Nauseef, William M., additional, Nayak, Jennifer L., additional, Neill, Marguerite A., additional, O'Donnell, Judith A., additional, Ohl, Christopher A., additional, Okhuysen, Pablo C., additional, Onderdonk, Andrew B., additional, Opal, Steven M., additional, Orenstein, Walter A., additional, Osmon, Douglas R., additional, Osterholm, Michael T., additional, Ostroff, Stephen M., additional, Oxman, Michael N., additional, Paessler, Slobodan, additional, Page, Andrea V., additional, Pai, Manjunath P., additional, Palmore, Tara N., additional, Palraj, Raj, additional, Pappas, Peter G., additional, Pasternack, Mark S., additional, Patterson, Thomas F., additional, Pavan-Langston, Deborah, additional, Pegues, David A., additional, Penn, Robert L., additional, Perfect, John R., additional, Perlman, Stanley, additional, Petersen, Brett W., additional, Peterson, Phillip K., additional, Petri, William A., additional, Petti, Cathy A., additional, Philips, Jennifer A., additional, Philley, Julie V., additional, Phillips, Michael, additional, Pickering, Larry K., additional, Piot, Peter, additional, Pogue, Jason M., additional, Pop-Vicas, Aurora, additional, Portal-Celhay, Cynthia, additional, Powers, John H., additional, Price, Richard N., additional, Que, Yok-Ai, additional, Radolf, Justin D., additional, Ram, Sanjay, additional, Raoult, Didier, additional, Ravdin, Jonathan I., additional, Ray, Stuart C., additional, Reboli, Annette C., additional, Reitz, Marvin S., additional, Relman, David A., additional, Renault, Cybèle A., additional, Restrepo, Angela, additional, Rex, John H., additional, Rhee, Elizabeth G., additional, Roberts, Norbert J., additional, Romero, José R., additional, Rothman, Alan L., additional, Roy, Craig R., additional, Ruoff, Kathryn L., additional, Rupp, Mark E., additional, Rupprecht, Charles E., additional, Russo, Thomas A., additional, Rutala, William A., additional, Ryan, Edward T., additional, Safdar, Amar, additional, Sajadi, Mohammad M., additional, Salazar, Juan C., additional, Sarria, Juan Carlos, additional, Savoia, Maria C., additional, Sax, Paul E., additional, Scheld, W. Michael, additional, Schiffer, Joshua T., additional, Schlossberg, David, additional, Schneider, Thomas, additional, Schuchat, Anne, additional, Schwebke, Jane R., additional, Sears, Cynthia L., additional, Segal, Leopoldo N., additional, Sendi, Parham, additional, Sepkowitz, Kent A., additional, Septimus, Edward J., additional, Seregin, Alexey, additional, Shulman, Stanford T., additional, Siberry, George K., additional, Siddiqi, Omar K., additional, Sifri, Costi D., additional, Simberkoff, Michael S., additional, Simonetti, Francesco R., additional, Singh, Kamaljit, additional, Singh, Nina, additional, Singh, Upinder, additional, Sinner, Scott W., additional, Sivapalasingam, Sumathi, additional, Slater, Leonard N., additional, Smulian, A. George, additional, Sobel, Jack D., additional, Sohail, M. Rizwan, additional, Soper, David E., additional, Sorrell, Tania C., additional, Steckelberg, James M., additional, Steere, Allen C., additional, Steigbigel, Neal H., additional, Steinberg, James P., additional, Stephens, David S., additional, Sterling, Timothy R., additional, Stevens, David A., additional, Stevens, Dennis L., additional, Strahilevitz, Jacob, additional, Stratton, Charles W., additional, Suffredini, Anthony F., additional, Suh, Kathryn N., additional, Sulkowski, Mark S., additional, Swartz, Morton N., additional, Talbot, Thomas R., additional, Tan, C. Sabrina, additional, Tan, Ming, additional, Thio, Chloe Lynne, additional, Thomas, David L., additional, Thomas, Lora D., additional, Thomas, Stephen J., additional, Thorner, Anna R., additional, María Tobón, Angela, additional, Tramont, Edmund C., additional, Treanor, John J., additional, Trubiano, Jason, additional, Tsibris, Athe M.N., additional, Tunkel, Allan R., additional, Turner, Ronald B., additional, Tyler, Kenneth L., additional, Uluer, Ahmet, additional, van de Beek, Diederik, additional, van der Velden, Walter J.F.M., additional, Vannier, Edouard G., additional, Van, Trevor C., additional, Versalovic, James, additional, Viscoli, Claudio, additional, Wald, Ellen R., additional, Waldor, Matthew K., additional, Walker, David H., additional, Wallace, Richard J., additional, Walsh, Edward E., additional, Walsh, Stephen R., additional, Walzer, Peter D., additional, Wanke, Christine A., additional, Warren, Cirle A., additional, Washburn, Ronald G., additional, Waters, Valerie, additional, Weber, David J., additional, Weiden, Michael D., additional, Weinberg, Geoffrey A., additional, Weisdorf, Daniel J., additional, Weiss, Louis M., additional, Welch, David F., additional, Wellems, Thomas E., additional, Wenzel, Richard P., additional, Wharton, Melinda, additional, White, A. Clinton, additional, Whitley, Richard J., additional, Wilson, Walter R., additional, Wortmann, Glenn W., additional, Wright, William F., additional, Young, Jo-Anne H., additional, Young, Vincent B., additional, Yun, Nadezhda, additional, Zimmerli, Werner, additional, Zinner, Stephen H., additional, and Zurlo, John J., additional
- Published
- 2015
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22. A “body armor” of leukemia cutis
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Janssen, Nico A.F., Hebeda, Konnie M., Stevens, Wendy B.C., and van der Velden, Walter J.F.M.
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- 2015
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23. Atypical presentation of ‘acalculous cholecystitis’ with marked isolated hyperbilirubinaemia in patients treated for haematological malignancies
- Author
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Berrevoets, Marvin A.H., Hermans, John J., Wanten, Geert J.A., and van der Velden, Walter J.F.M.
- Published
- 2015
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24. Anti-thymocyte globulin with CsA and MMF as GVHD prophylaxis in nonmyeloablative HLA-mismatched allogeneic HCT
- Author
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CTI De Witte, MS Hematologie, Infection & Immunity, Regenerative Medicine and Stem Cells, Cancer, CTI Kuball, van der Velden, Walter J.F.M., Choi, Goda, de Witte, Moniek A., van der Meer, Arnold, de Haan, Anton F.J., Blijlevens, Nicole M.A., Huls, Gerwin, Kuball, Jürgen, van Dorp, Suzanne, CTI De Witte, MS Hematologie, Infection & Immunity, Regenerative Medicine and Stem Cells, Cancer, CTI Kuball, van der Velden, Walter J.F.M., Choi, Goda, de Witte, Moniek A., van der Meer, Arnold, de Haan, Anton F.J., Blijlevens, Nicole M.A., Huls, Gerwin, Kuball, Jürgen, and van Dorp, Suzanne
- Published
- 2021
25. 305 - Infections in the Immunocompromised Host: General Principles
- Author
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Blijlevens, Nicole M.A. and van der Velden, Walter J.F.M.
- Published
- 2020
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26. Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients
- Author
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Plantinga, Theo S., van der Velden, Walter J.F.M., Ferwerda, Bart, van Spriel, Annemiek B., Adema, Gosse, Feuth, Ton, Donnelly, J. Peter, Brown, Gordon D., Kullberg, Bart-Jan, Blijlevens, Nicole M.A., and Netea, Mihai G.
- Subjects
Genetic polymorphisms -- Research ,Genetic polymorphisms -- Control ,Candida -- Research ,Candida -- Physiological aspects ,Candidiasis -- Prevention ,Hematopoietic stem cells -- Transplantation ,Hematopoietic stem cells -- Usage ,Hematopoietic stem cells -- Patient outcomes ,Health ,Health care industry - Published
- 2009
27. BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment
- Author
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Cirovic, Branko, primary, de Bree, L. Charlotte J., additional, Groh, Laszlo, additional, Blok, Bas A., additional, Chan, Joyce, additional, van der Velden, Walter J.F.M., additional, Bremmers, M.E.J., additional, van Crevel, Reinout, additional, Händler, Kristian, additional, Picelli, Simone, additional, Schulte-Schrepping, Jonas, additional, Klee, Kathrin, additional, Oosting, Marije, additional, Koeken, Valerie A.C.M., additional, van Ingen, Jakko, additional, Li, Yang, additional, Benn, Christine S., additional, Schultze, Joachim L., additional, Joosten, Leo A.B., additional, Curtis, Nigel, additional, Netea, Mihai G., additional, and Schlitzer, Andreas, additional
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- 2020
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- View/download PDF
28. Busulfan-Dependent Hepatotoxicity of Antithymocyte Globulin Formulations During Conditioning for Hematopoietic Stem Cell Transplantation
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van der Velden, Walter J.F.M., de Weerd-de Jong, Esther C., de Haan, Anton F.J., and Blijlevens, Nicole M.A.
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- 2018
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29. Striatal Involvement in Neurodegenerative Langerhans Cell Histiocytosis
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de Haan, Sven, primary, van der Velden, Walter J.F.M., additional, and Meijer, Frederick J.A., additional
- Published
- 2019
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30. Long-term follow-up of a trial comparing post-remission treatment with autologous or allogeneic bone marrow transplantation or intensive chemotherapy in younger acute myeloid leukemia patients
- Author
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Baron, Frédéric, primary, Efficace, Fabio, additional, Cannella, Laura, additional, Willemze, Roel, additional, Vignetti, Marco, additional, Muus, Petra, additional, Marie, Jean-Pierre, additional, Ferrero, Dario, additional, Fazi, Paola, additional, La Sala, Edoardo, additional, Bourhis, Jean-Henri, additional, Fabbiano, Francesco, additional, Bosi, Alberto, additional, Sborgia, Marco, additional, Martinelli, Giovanni, additional, Wittnebel, Sebastian, additional, Trisolini, Silvia, additional, Petti, Maria Concetta, additional, Halkes, Constantijn J.M., additional, van der Velden, Walter J.F.M., additional, de Witte, Theo, additional, Amadori, Sergio, additional, Zittoun, Robert A, additional, and Suciu, Stefan, additional
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- 2019
- Full Text
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31. Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease
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Groth, Christoph, primary, van Groningen, Lenneke F.J., additional, Matos, Tiago R., additional, Bremmers, Manita E., additional, Preijers, Frank W.M.B., additional, Dolstra, Harry, additional, Reicherts, Christian, additional, Schaap, Nicolaas P.M., additional, van Hooren, Eric H.G., additional, IntHout, Joanna, additional, Masereeuw, Rosalinde, additional, Netea, Mihai G., additional, Levine, John E., additional, Morales, George, additional, Ferrara, James L., additional, Blijlevens, Nicole M.A., additional, van Oosterhout, Ypke V.J.M., additional, Stelljes, Matthias, additional, and van der Velden, Walter J.F.M., additional
- Published
- 2019
- Full Text
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32. Colaboradores
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Aagaard, Kjersti, Abdallah, Marie, Abrahamian, Fredrick M., Agnihotri, Shruti, Ahmed, Sana S., Allos, Ban Mishu, Alqahtani, Saleh A., Anderson, Jeffrey L., Andes, David R., Andrews, Jason R., Aoki, Fred Y., Apicella, Michael A., Araos, Rafael, Ard, Kevin L., Arias, Cesar A., Aronoff, David M., Aronson, Naomi E., Augenbraun, Michael H., Auwaerter, Paul G., Averhoff, Francisco, Azar, Dimitri T., Babu, Tara M., Bachmann, Laura Hinkle, Baddour, Larry M., Baden, Lindsey R., Baker, Carol J., Ballard, Sarah-Blythe, Barber, Gerard R., Barnes, Scott D., Barouch, Dan H., Barrett, Alan D., Barshak, Miriam Baron, Bartelt, Luther A., Basavaraju, Sridhar V., Batteiger, Byron E., Baum, Stephen G., Bayer, Arnold S., Beckham, J. David, Beekmann, Susan E., Beigi, Richard H., Bennett, John E., Berbari, Elie F., Bertino, Joseph S., Jr., Bhimraj, Adarsh, Birch, Torrey Boland, Birdsall, Holly H., Blackburn, Brian G., Blanton, Lucas S., Blaser, Martin J., Blazes, David L., Bleck, Thomas P., Blijlevens, Nicole M.A., Blyth, Dana M., Boggild, Andrea K., Bogoch, Isaac I., Bonnez, William, Boothroyd, John C., Borio, Luciana L., Bosque, Patrick J., Braden, Christopher R., Branche, Angela R., Britt, William J., Brook, Itzhak, Brouwer, Matthijs C., Brown, Kevin E., Brown, Patricia, Brown-Elliott, Barbara A., Bruhn, Roberta L., Bryant, Amy E., Burd, Eileen M., Burns, Jane C., Bush, Larry M., Casadevall, Arturo, Caserta, Mary T., Castagnola, Elio, Chaisson, Richard E., Chapman, Stephen J., Chappell, Catherine A., Chappell, James D., Chen, Lea Ann, Chen, Sharon C-A., Chiang, Augusto Dulanto, Chopra, Sanjiv, Chow, Anthony W., Clancy, Cornelius J., Clark, Richard B., Cohen, Jeffrey I., Cohen, Myron S., Cohen, Yehuda Z., Cohen-Poradosu, Ronit, Cohn, Susan E., Colton, Benjamin, Connors, Mark, Copeland, Nathanial K., Corey, Lawrence, Cosgrove, Sara E., Cottrell, Mackenzie L., Cover, Timothy L., Cox, Heather L., Crass, Ryan L., Cunha, Cheston B., Curran, James W., Currie, Bart J., D’Agata, Erika, Daly, Jennifer S., Damon, Inger K., Darouiche, Rabih O., Dawid, Suzanne, Deepe, George S., Jr., Dekker, John P., del Rio, Carlos, DeLeo, Frank R., DeMuri, Gregory P., Dermody, Terence S., Dewar, Robin, Diaz, James H., Dieffenbach, Carl W., Dienstag, Jules L., Doi, Yohei, Dolin, Raphael, Donowitz, Gerald R., Donskey, Curtis J., Dormitzer, Philip R., Dumler, J. Stephen, Dupnik, Kathryn, DuPont, Herbert L., Durack, David T., Durand, Marlene L., Duval, Xavier, Edelstein, Paul H., Edwards, John E., Jr., Edwards, Morven S., Ellison, Richard T., III, Embry, Alan C., Endy, Timothy P., Engleberg, N. Cary, Englund, Janet A., Erdem, Hakan, Ernst, Peter B., Fairhurst, Rick M., Fairley, Jessica K., Falkow, Stanley, Falsey, Ann R., Fauci, Anthony S., Fekete, Thomas, Fey, Paul D., Fine, Steven M., Fitzgerald, Daniel W., Flores, Anthony R., Fournier, Pierre-Edouard, Fowler, Vance G., Jr., Freedman, David O., Friedlander, Arthur M., Galgiani, John N., Gallin, John I., Gallo, Robert C., Gandhi, Monica, Garrett, Wendy S., Gauthier, Gregory M., Gaydos, Charlotte A., Gea-Banacloche, Juan C., Geisbert, Thomas W., Gelfand, Jeffrey A., Gelone, Steven P., Gerding, Dale N., Gershon, Anne A., Gilsdorf, Janet R., Giri, Pushpanjali, Gold, Howard S., Goldstein, Ellie J.C., González-Marín, Ángel, Graman, Paul S., Grayson, M. Lindsay, Greenberg, David, Greene, Matthew H., Griffin, Patricia M., Griffith, David E., Guerrant, Richard L., Gul, Hanefi C., Haake, David A., Haas, David W., Haidar, Ghady, Hallak, Joelle, Halperin, Scott A., Hammerschlag, Margaret R., Haque, Rashidul, Harris, Jason B., Hartzell, Joshua D., Hasbun, Rodrigo, Hawkins, Claudia, Hay, Roderick J., Henderson, David K., High, Kevin P., Hill, Adrian V.S., Hinman, Alan R., Hirsch, Martin S., Hochman, Sarah, Hoen, Bruno, Hohl, Tobias M., Holland, Steven M., Holland, Thomas L., Holzman, Robert S., Hooper, David C., Hooton, Thomas M., Hoover, Susan E., Horowitz, Harold W., Horton, James M., Hospenthal, Duane R., Hotez, Peter J., Hynes, Noreen A., Iovine, Nicole M., Ison, Michael G., Jaggi, Preeti, Janda, J. Michael, Janoff, Edward N., Jernigan, Daniel, Johannsen, Eric C., Johnson, Jennie E., Juliano, Jonathan J., Kamboj, Mini, Kasper, Dennis L., Kaye, Donald, Kaye, Keith S., Kaye, Kenneth M., Kazura, James W., Keystone, Jay S., Khabbaz, Rima F., Khan, David A., Khudyakov, Yury, Kim, Rose, King, Charles H., Kirchhoff, Louis V., Kirkpatrick, Beth D., Kiyono, Hiroshi, Klein, Bruce S., Klompas, Michael, Knoll, Bettina M., Knowlton, Kirk U., Koehler, Jane E., Kohlhoff, Stephan A., Könönen, Eija, Kontoyiannis, Dimitrios P., Koralnik, Igor J., Korpe, Poonum S., Koshy, Anita A., Kovacs, Joseph A., Kroger, Andrew T., Kuehnert, Matthew J., Kumar, Nalin M., Kuruvilla, Merin Elizabeth, LaRocque, Regina C., LaSalvia, Mary T., Leaf, Howard L., Leggett, James E., Lepak, Alexander J., Levett, Paul N., Levine, Donald P., Levison, Matthew E., Levitt, Alexandra, Lewis, Russell E., Liles, W. Conrad, Lima, Aldo A.M., Limaye, Ajit P., Lionakis, Michail S., Lipkin, W. Ian, Litman, Nathan, Luna, Ruth Ann, Lutgring, Joseph D., MacDougall, Conan, Maddocks, Susan, Madoff, Lawrence C., Magill, Alan J., Maguire, James H., Maldarelli, Frank, Markoff, Lewis, Marrazzo, Jeanne M., Marrie, Thomas J., Marth, Thomas, Martin, David H., Martin, Gregory J., Marty, Francisco M., Maslow, Melanie Jane, Masur, Henry, Mawle, Alison, Mayer, Kenneth H., McCarthy, James S., McCormack, William, McGowan, Catherine C., McIntosh, Kenneth, Mead, Paul S., Mejia, Rojelio, Mekala, Vijayashree, Messonnier, Nancy, Mikulska, Małgorzata, Miller, Robert F., Miller, Samuel I., Miller, William R., Moffa, Matthew, Moir, Susan, Montoya, José G., Moonah, Shannon N., Moore, Thomas A., Moreillon, Philippe, Morgan, Janet, Morris, J. Glenn, Jr., Munita, Jose M., Murphy, Edward L., Murphy, Timothy F., Murray, Barbara E., Murray, Clinton K., Musher, Daniel M., Mylonakis, Eleftherios, Nagel, Jerod L., Naggie, Susanna, Nannini, Esteban C., Nash, Theodore E., Nauseef, William M., Nayak, Jennifer L., Neill, Marguerite A., Nelson, George E., Nelson, Joanna K., Nesbitt, Whitney J., Nguyen, M. Hong, O’Donnell, Judith A., Ohl, Christopher A., Okhuysen, Pablo C., Onderdonk, Andrew B., Opal, Steven M., Orenstein, Walter A., Osmon, Douglas R., Oxman, Michael N., Paessler, Slobodan, Page, Andrea V., Pai, Manjunath P., Palmore, Tara N., Palraj, Raj, Pappas, Peter G., Paris, Daniel H., Parks, Tom, Parsonnet, Julie, Parta, Mark, Pasternack, Mark S., Pastula, Daniel M., Patel, Robin, Patterson, Thomas F., Pavan-Langston, Deborah, Pegues, David A., Pelton, Stephen I., Penn, Robert L., Perfect, John R., Perkins, Ryan, Perlman, Stanley, Petersen, Brett W., Petri, William A., Jr., Petti, Cathy A., Philips, Jennifer A., Philley, Julie V., Phillips, Michael, Pickering, Larry K., Piot, Peter, Pogue, Jason M., Polsky, Bruce, Pop-Vicas, Aurora, Portal-Celhay, Cynthia, Powers, John H., III, Price, Richard N., Que, Yok-Ai, Radolf, Justin D., Ram, Sanjay, Ramakrishnan, Lalita, Raoult, Didier, Ravdin, Jonathan I., Reboli, Annette C., Redel, Henry, Reitz, Marvin S., Jr., Relman, David A., Reno, Hilary E.L., Restrepo-Moreno, Ángela, Rex, John H., Rhee, Elizabeth G., Roberts, Norbert J., Jr., Romanovsky, Andrej A., Romero, José R., Rose, Stacey R., Rosenberg, Ronald, Rothman, Alan L., Roy, Craig R., Ruoff, Kathryn L., Rupp, Mark E., Rupprecht, Charles E., Russo, Thomas A., Rutala, William A., Ryan, Edward T., Sajadi, Mohammad M., Salazar, Juan C., Saleeb, Paul G., Sarria, Juan Carlos, Savoia, Maria C., Sax, Paul E., Schiffer, Joshua T., Schlossberg, David, Schneider, Thomas, Schwebke, Jane R., Sears, Cynthia L., Segal, Leopoldo N., Sendi, Parham, Sepkowitz, Kent A., Seregin, Alexey, Shulman, Stanford T., Siberry, George K., Siddiqi, Omar K., Sifri, Costi D., Simberkoff, Michael S., Simonetti, Francesco, Singh, Nina, Singh, Upinder, Smulian, A. George, Sobel, Jack D., Sohail, M. Rizwan, Sorrell, Tania C., Spellberg, Brad, Steckelberg, James M., Steere, Allen C., Steinberg, James P., Stephens, David S., Stephenson, Kathryn E., Sterling, Timothy R., Stevens, David A., Stevens, Dennis L., Stoner, Bradley P., Strahilevitz, Jacob, IV, Charles W. Stratton, Strnad, Luke C., Suh, Kathryn N., Sulkowski, Mark S., Swartz, Morton N., Talati, Naasha J., Talbot, Thomas R., Tan, C. Sabrina, Tan, Ming, Tande, Aaron J., Tesini, Brenda L., Thio, Chloe Lynne, Thomas, Stephen J., Thompson, George R., III, Thorner, Anna R., Tobón-Orozco, Ángela Ma., Tramont, Edmund C., Trautner, Barbara W., Treanor, John J., Trivedi, Hirsh D., Trubiano, Jason, Tsibris, Athe M.N., Tunkel, Allan R., Tyler, Kenneth L., Uluer, Ahmet Z., Urban, Marguerite A., Ustun, Celalettin, Uyeki, Timothy M., van de Beek, Diederik, van der Poll, Tom, van der Velden, Walter J.F.M., Van Schooneveld, Trevor C., Vannier, Edouard, Vellozzi, Claudia, Versalovic, James, Vijayan, Vini, Viscoli, Claudio, Wald, Ellen R., Waldor, Matthew K., Walker, David H., Wallace, Richard J., Jr., Walsh, Edward E., Walsh, Stephen R., Walzer, Peter D., Wanke, Christine A., Ward, Honorine D., Warren, Cirle A., Washburn, Ronald G., Waters, Valerie, Watkins, Richard R., Watts, Matthew R., Weatherhead, Jill, Weber, David J., Weiden, Michael D., Weinberg, Geoffrey A., Weiss, Louis M., Wellems, Thomas E., White, A. Clinton, Jr., Whitley, Richard J., Wiersinga, Willem Joost, Williams, Brett, Wilson, Walter R., Winslow, Dean L., Winthrop, Kevin L., Wong, Karen K., Wortmann, Glenn W., Wright, William F., Wyles, David L., Young, Jo-Anne H., Young, Vincent Bensan, Yun, Nadezhda, Zimmerli, Werner, Zinner, Stephen H., and Zurlo, John J.
- Published
- 2021
- Full Text
- View/download PDF
33. 305 - Infecciones en huéspedes inmunocomprometidos: principios generales
- Author
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Blijlevens, Nicole M.A. and van der Velden, Walter J.F.M.
- Published
- 2021
- Full Text
- View/download PDF
34. Combination Therapy with Inolimomab and Etanercept for Severe Steroid-Refractory Acute Graft-versus-Host Disease
- Author
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van Groningen, Lenneke F.J., Liefferink, Aleida M., de Haan, Anton F.J., Schaap, Nicolaas P.M., Donnelly, J. Peter, Blijlevens, Nicole M.A., and van der Velden, Walter J.F.M.
- Published
- 2016
- Full Text
- View/download PDF
35. Contributors
- Author
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Aagaard, Kjersti, Abdallah, Marie, Abrahamian, Fredrick M., Agnihotri, Shruti, Ahmed, Sana S., Allos, Ban Mishu, Alqahtani, Saleh A., Anderson, Jeffrey L., Andes, David R., Andrews, Jason R., Aoki, Fred Y., Apicella, Michael A., Araos, Rafael, Ard, Kevin L., Arias, Cesar A., Aronoff, David M., Aronson, Naomi E., Augenbraun, Michael H., Auwaerter, Paul G., Averhoff, Francisco, Azar, Dimitri T., Babu, Tara M., Bachmann, Laura Hinkle, Baddour, Larry M., Baden, Lindsey R., Baker, Carol J., Ballard, Sarah-Blythe, Barber, Gerard R., Barnes, Scott D., Barouch, Dan H., Barrett, Alan D., Barshak, Miriam Baron, Bartelt, Luther A., Basavaraju, Sridhar V., Batteiger, Byron E., Baum, Stephen G., Bayer, Arnold S., Beckham, J. David, Beekmann, Susan E., Beigi, Richard H., Bennett, John E., Berbari, Elie F., Bertino, Joseph S., Jr., Bhimraj, Adarsh, Birch, Torrey Boland, Birdsall, Holly H., Blackburn, Brian G., Blanton, Lucas S., Blaser, Martin J., Blazes, David L., Bleck, Thomas P., Blijlevens, Nicole M.A., Blyth, Dana M., Boggild, Andrea K., Bogoch, Isaac I., Bonnez, William, Boothroyd, John C., Borio, Luciana L., Bosque, Patrick J., Braden, Christopher R., Branche, Angela R., Britt, William J., Brook, Itzhak, Brouwer, Matthijs C., Brown, Kevin E., Brown, Patricia, Brown-Elliott, Barbara A., Bruhn, Roberta L., Bryant, Amy E., Burd, Eileen M., Burns, Jane C., Bush, Larry M., Casadevall, Arturo, Caserta, Mary T., Castagnola, Elio, Chaisson, Richard E., Chapman, Stephen J., Chappell, Catherine A., Chappell, James D., Chen, Lea Ann, Chen, Sharon C-A., Chiang, Augusto Dulanto, Chopra, Sanjiv, Chow, Anthony W., Clancy, Cornelius J., Clark, Richard B., Cohen, Jeffrey I., Cohen, Myron S., Cohen, Yehuda Z., Cohen-Poradosu, Ronit, Cohn, Susan E., Colton, Benjamin, Connors, Mark, Copeland, Nathanial K., Corey, Lawrence, Cosgrove, Sara E., Cottrell, Mackenzie L., Cover, Timothy L., Cox, Heather L., Crass, Ryan L., Cunha, Cheston B., Curran, James W., Currie, Bart J., D'Agata, Erika, Daly, Jennifer S., Damon, Inger K., Darouiche, Rabih O., Dawid, Suzanne, Deepe, George S., Jr., Dekker, John P., del Rio, Carlos, DeLeo, Frank R., DeMuri, Gregory P., Dermody, Terence S., Dewar, Robin, Diaz, James H., Dieffenbach, Carl W., Dienstag, Jules L., Doi, Yohei, Dolin, Raphael, Donowitz, Gerald R., Donskey, Curtis J., Dormitzer, Philip R., Dumler, J. Stephen, Dupnik, Kathryn, DuPont, Herbert L., Durack, David T., Durand, Marlene L., Duval, Xavier, Edelstein, Paul H., Edwards, John E., Jr., Edwards, Morven S., Ellison, Richard T., III, Embry, Alan C., Endy, Timothy P., Engleberg, N. Cary, Englund, Janet A., Erdem, Hakan, Ernst, Peter B., Fairhurst, Rick M., Fairley, Jessica K., Falkow, Stanley, Falsey, Ann R., Fauci, Anthony S., Fekete, Thomas, Fey, Paul D., Fine, Steven M., Fitzgerald, Daniel W., Flores, Anthony R., Fournier, Pierre-Edouard, Fowler, Vance G., Jr., Freedman, David O., Friedlander, Arthur M., Galgiani, John N., Gallin, John I., Gallo, Robert C., Gandhi, Monica, Garrett, Wendy S., Gauthier, Gregory M., Gaydos, Charlotte A., Gea-Banacloche, Juan C., Geisbert, Thomas W., Gelfand, Jeffrey A., Gelone, Steven P., Gerding, Dale N., Gershon, Anne A., Gilsdorf, Janet R., Giri, Pushpanjali, Gold, Howard S., Goldstein, Ellie J.C., González-Marín, Ángel, Graman, Paul S., Grayson, M. Lindsay, Greenberg, David, Greene, Matthew H., Griffin, Patricia M., Griffith, David E., Guerrant, Richard L., Gul, Hanefi C., Haake, David A., Haas, David W., Haidar, Ghady, Hallak, Joelle, Halperin, Scott A., Hammerschlag, Margaret R., Haque, Rashidul, Harris, Jason B., Hartzell, Joshua D., Hasbun, Rodrigo, Hawkins, Claudia, Hay, Roderick J., Henderson, David K., High, Kevin P., Hill, Adrian V.S., Hinman, Alan R., Hirsch, Martin S., Hochman, Sarah, Hoen, Bruno, Hohl, Tobias M., Holland, Steven M., Holland, Thomas L., Holzman, Robert S., Hooper, David C., Hooton, Thomas M., Hoover, Susan E., Horowitz, Harold W., Horton, James M., Hospenthal, Duane R., Hotez, Peter J., Hynes, Noreen A., Iovine, Nicole M., Ison, Michael G., Jaggi, Preeti, Janda, J. Michael, Janoff, Edward N., Jernigan, Daniel, Johannsen, Eric C., Johnson, Jennie E., Juliano, Jonathan J., Kamboj, Mini, Kasper, Dennis L., Kaye, Donald, Kaye, Keith S., Kaye, Kenneth M., Kazura, James W., Keystone, Jay S., Khabbaz, Rima F., Khan, David A., Khudyakov, Yury, Kim, Rose, King, Charles H., Kirchhoff, Louis V., Kirkpatrick, Beth D., Kiyono, Hiroshi, Klein, Bruce S., Klompas, Michael, Knoll, Bettina M., Knowlton, Kirk U., Koehler, Jane E., Kohlhoff, Stephan A., Könönen, Eija, Kontoyiannis, Dimitrios P., Koralnik, Igor J., Korpe, Poonum S., Koshy, Anita A., Kovacs, Joseph A., Kroger, Andrew T., Kuehnert, Matthew J., Kumar, Nalin M., Kuruvilla, Merin Elizabeth, LaRocque, Regina C., LaSalvia, Mary T., Leaf, Howard L., Leggett, James E., Lepak, Alexander J., Levett, Paul N., Levine, Donald P., Levison, Matthew E., Levitt, Alexandra, Lewis, Russell E., Liles, W. Conrad, Lima, Aldo A.M., Limaye, Ajit P., Lionakis, Michail S., Lipkin, W. Ian, Litman, Nathan, Luna, Ruth Ann, Lutgring, Joseph D., MacDougall, Conan, Maddocks, Susan, Madoff, Lawrence C., Magill, Alan J., Maguire, James H., Maldarelli, Frank, Markoff, Lewis, Marrazzo, Jeanne M., Marrie, Thomas J., Marth, Thomas, Martin, David H., Martin, Gregory J., Marty, Francisco M., Maslow, Melanie Jane, Masur, Henry, Mawle, Alison, Mayer, Kenneth H., McCarthy, James S., McCormack, William, McGowan, Catherine C., McIntosh, Kenneth, Mead, Paul S., Mejia, Rojelio, Mekala, Vijayashree, Messonnier, Nancy, Mikulska, Małgorzata, Miller, Robert F., Miller, Samuel I., Miller, William R., Moffa, Matthew, Moir, Susan, Montoya, José G., Moonah, Shannon N., Moore, Thomas A., Moreillon, Philippe, Morgan, Janet, Morris, J. Glenn, Jr., Munita, Jose M., Murphy, Edward L., Murphy, Timothy F., Murray, Barbara E., Murray, Clinton K., Musher, Daniel M., Mylonakis, Eleftherios, Nagel, Jerod L., Naggie, Susanna, Nannini, Esteban C., Nash, Theodore E., Nauseef, William M., Nayak, Jennifer L., Neill, Marguerite A., Nelson, George E., Nelson, Joanna K., Nesbitt, Whitney J., Nguyen, M. Hong, O'Donnell, Judith A., Ohl, Christopher A., Okhuysen, Pablo C., Onderdonk, Andrew B., Opal, Steven M., Orenstein, Walter A., Osmon, Douglas R., Oxman, Michael N., Paessler, Slobodan, Page, Andrea V., Pai, Manjunath P., Palmore, Tara N., Palraj, Raj, Pappas, Peter G., Paris, Daniel H., Parks, Tom, Parsonnet, Julie, Parta, Mark, Pasternack, Mark S., Pastula, Daniel M., Patel, Robin, Patterson, Thomas F., Pavan-Langston, Deborah, Pegues, David A., Pelton, Stephen I., Penn, Robert L., Perfect, John R., Perkins, Ryan, Perlman, Stanley, Petersen, Brett W., Petri, William A., Jr., Petti, Cathy A., Philips, Jennifer A., Philley, Julie V., Phillips, Michael, Pickering, Larry K., Piot, Peter, Pogue, Jason M., Polsky, Bruce, Pop-Vicas, Aurora, Portal-Celhay, Cynthia, Powers, John H., III, Price, Richard N., Que, Yok-Ai, Radolf, Justin D., Ram, Sanjay, Ramakrishnan, Lalita, Raoult, Didier, Ravdin, Jonathan I., Reboli, Annette C., Redel, Henry, Reitz, Marvin S., Jr., Relman, David A., Reno, Hilary E.L., Restrepo-Moreno, Ángela, Rex, John H., Rhee, Elizabeth G., Roberts, Norbert J., Jr., Romanovsky, Andrej A., Romero, José R., Rose, Stacey R., Rosenberg, Ronald, Rothman, Alan L., Roy, Craig R., Ruoff, Kathryn L., Rupp, Mark E., Rupprecht, Charles E., Russo, Thomas A., Rutala, William A., Ryan, Edward T., Sajadi, Mohammad M., Salazar, Juan C., Saleeb, Paul G., Sarria, Juan Carlos, Savoia, Maria C., Sax, Paul E., Schiffer, Joshua T., Schlossberg, David, Schneider, Thomas, Schwebke, Jane R., Sears, Cynthia L., Segal, Leopoldo N., Sendi, Parham, Sepkowitz, Kent A., Seregin, Alexey, Shulman, Stanford T., Siberry, George K., Siddiqi, Omar K., Sifri, Costi D., Simberkoff, Michael S., Simonetti, Francesco, Singh, Nina, Singh, Upinder, Smulian, A. George, Sobel, Jack D., Sohail, M. Rizwan, Sorrell, Tania C., Spellberg, Brad, MD, Steckelberg, James M., Steere, Allen C., Steinberg, James P., Stephens, David S., Stephenson, Kathryn E., Sterling, Timothy R., Stevens, David A., Stevens, Dennis L., Stoner, Bradley P., Strahilevitz, Jacob, Stratton, Charles W., IV, Strnad, Luke C., Suh, Kathryn N., Sulkowski, Mark S., Swartz, Morton N., Talati, Naasha J., Talbot, Thomas R., Tan, C. Sabrina, Tan, Ming, Tande, Aaron J., Tesini, Brenda L., Thio, Chloe Lynne, Thomas, Stephen J., Thompson, George R., III, Thorner, Anna R., Tobón-Orozco, Ángela Ma., Tramont, Edmund C., Trautner, Barbara W., Treanor, John J., Trivedi, Hirsh D., Trubiano, Jason, Tsibris, Athe M.N., Tunkel, Allan R., Tyler, Kenneth L., Uluer, Ahmet Z., Urban, Marguerite A., Ustun, Celalettin, Uyeki, Timothy M., van de Beek, Diederik, van der Poll, Tom, van der Velden, Walter J.F.M., Van, Trevor C., Vannier, Edouard, Vellozzi, Claudia, Versalovic, James, Vijayan, Vini, Viscoli, Claudio, Wald, Ellen R., Waldor, Matthew K., Walker, David H., Wallace, Richard J., Jr., Walsh, Edward E., Walsh, Stephen R., Walzer, Peter D., Wanke, Christine A., Ward, Honorine D., Warren, Cirle A., Washburn, Ronald G., Waters, Valerie, Watkins, Richard R., Watts, Matthew R., Weatherhead, Jill, Weber, David J., Weiden, Michael D., Weinberg, Geoffrey A., Weiss, Louis M., Wellems, Thomas E., White, A. Clinton, Jr., Whitley, Richard J., Wiersinga, Willem Joost, Williams, Brett, Wilson, Walter R., Winslow, Dean L., Winthrop, Kevin L., Wong, Karen K., Wortmann, Glenn W., Wright, William F., Wyles, David L., Young, Jo-Anne H., Young, Vincent Bensan, Yun, Nadezhda, Zimmerli, Werner, Zinner, Stephen H., and Zurlo, John J.
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- 2020
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36. 309 - Infections in the Immunocompromised Host: General Principles
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Donnelly, J. Peter, Blijlevens, Nicole M.A., and van der Velden, Walter J.F.M.
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- 2015
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37. Long-Term Follow-up of Patients with Corticosteroid-Refractory Graft-Versus-Host Disease Treated with Ruxolitinib
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Zeiser, Robert, primary, Burchert, Andreas, additional, Lengerke, Claudia, additional, Verbeek, Mareike, additional, Maas-Bauer, Kristina, additional, Metzelder, Stephan, additional, Spoerl, Silvia, additional, Ditschkowski, Markus, additional, Ecsedi, Matyas, additional, Sockel, Katja, additional, Ayuk, Francis, additional, Salem, Ajib, additional, Sicre de Fontbrune, Flore, additional, Na, Il-Kang, additional, Livius, Penter, additional, Holtick, Udo, additional, Wolf, Dominik, additional, Schuler, Esther, additional, Meyer, Everett, additional, Apostolova, Petya, additional, Bertz, Hartmut, additional, Marks, Reinhard, additional, Lübbert, Michael, additional, Wäsch, Ralph, additional, Scheid, Christof, additional, Stölzel, Friedrich, additional, Ordemann, Rainer, additional, Bug, Gesine, additional, Kobbe, Guido, additional, Shah, Omid, additional, Negrin, Robert S., additional, Brune, Mats, additional, Spyridonidis, Alexandros, additional, Schmitt-Graeff, Annette, additional, van der Velden, Walter J.F.M., additional, Huls, Gerwin, additional, Mielke, Stephan, additional, Grigoleit, Goetz Ulrich, additional, Kuball, Jurgen, additional, Flynn, Ryan P, additional, Ihorst, Gabriele, additional, Du, Jing, additional, Blazar, Bruce R., additional, Arnold, Renate, additional, Kröger, Nicolaus, additional, Passweg, Jakob R., additional, Halter, Joerg, additional, Socié, Gérard, additional, Beelen, Dietrich W., additional, Peschel, Christian, additional, Neubauer, Andreas, additional, Finke, Jürgen, additional, Duyster, Justus, additional, and von Bubnoff, Nikolas, additional
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- 2016
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38. Post-Remission Treatment with Autologous or Allogeneic Bone Marrow Transplantation or Intensive Chemotherapy in Younger AML Patients: Long-Term Follow-up Results of the EORTC/Gimema AML-8A Study
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Baron, Frederic, primary, Efficace, Fabio, additional, Cannella, Laura, additional, Mandelli, Franco, additional, Willemze, Roelof, additional, Muus, Petra, additional, Marie, Jean-Pierre, additional, Ferrero, Dario, additional, Dictus, Marlies, additional, Fazi, Paola, additional, La Sala, Edoardo, additional, Bourhis, Jean-Henri, additional, Fabbiano, Francesco, additional, Bosi, Alberto, additional, Sborgia, Marco, additional, Martinelli, Giovanni, additional, Bron, Dominique, additional, Petti, Maria C., additional, Halkes, Constantijn J.M., additional, van der Velden, Walter J.F.M., additional, Boccadoro, Mario, additional, Amadori, Sergio, additional, Zittoun, Robert A., additional, and Suciu, Stefan, additional
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- 2016
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39. Role of the Mycobiome in Human Acute Graft-versus-Host Disease
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van der Velden, Walter J.F.M., Netea, Mihai G., de Haan, Anton F.J., Huls, Gerwin A., Donnelly, J. Peter, and Blijlevens, Nicole M.A.
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- 2013
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40. Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis
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van de Veerdonk, Frank L., primary, Koenen, Hans J.P.M., additional, van der Velden, Walter J.F.M., additional, van der Meer, Jos W.M., additional, and Netea, Mihai G., additional
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- 2015
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41. Atypical presentation of ‘acalculous cholecystitis’ with marked isolated hyperbilirubinaemia in patients treated for haematological malignancies
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Berrevoets, Marvin A.H., primary, Hermans, John J., additional, Wanten, Geert J.A., additional, and van der Velden, Walter J.F.M., additional
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- 2014
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42. 309 - Infecciones en huéspedes inmunocomprometidos: principios generales
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Donnelly, J. Peter, Blijlevens, Nicole M.A., and van der Velden, Walter J.F.M.
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- 2016
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43. Genetic variants and the risk for invasive mould disease in immunocompromised hematology patients
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van der Velden, Walter J.F.M., primary, Blijlevens, Nicole M.A., additional, and Donnelly, J. Peter, additional
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- 2011
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44. Association of Disparities in Known Minor Histocompatibility Antigens with Relapse-Free Survival and Graft-Versus-Host-Disease Upon Allogeneic Stem Cell Transplantation,
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Hobo, Willemijn, primary, Broen, Kelly, additional, van der Velden, Walter J.F.M., additional, Greupink-Draaisma, Annelies, additional, Adisty, Niken, additional, Wouters, Yannick, additional, Kester, Michel G.D., additional, Fredrix, Hanny, additional, Jansen, Joop H., additional, van der Reijden, Bert A., additional, Falkenburg, J.H. Frederik, additional, de Witte, Theo, additional, Preijers, Frank W.M.B., additional, Schattenberg, Anton, additional, Feuth, Ton, additional, Blijlevens, Nicole N.A., additional, Schaap, Nicolaas, additional, and Dolstra, Harry, additional
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- 2011
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45. Splenic Gas As a Result of a Non-Hodgkin's Lymphoma in a Patient With Common Variable Immunodeficiency
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Croles, Frederik N., primary, Hebeda, Konnie M., additional, Kats-Ugurlu, Gürsah, additional, Hermans, John J., additional, Bonenkamp, Han J., additional, and van der Velden, Walter J.F.M., additional
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- 2011
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46. The incidence of acute graft-versus-host disease increases with Candida colonization depending the dectin-1 gene status
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van der Velden, Walter J.F.M., primary, Plantinga, Theo S., additional, Feuth, Ton, additional, Donnelly, J. Peter, additional, Netea, Mihai G., additional, and Blijlevens, Nicole M.A., additional
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- 2010
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47. Host-microbe interactions in stem cell transplantation; recognizing Candida in infection and inflammation
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van der Velden, Walter J.F.M., primary, Plantinga, Theo S., additional, Donnelly, J. Peter, additional, Kullberg, Bart-Jan, additional, Blijlevens, Nicole M.A., additional, and Netea, Mihai G., additional
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- 2010
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48. No Impact of Dectin-1 Polymorphism Y238X On the Outcome of Hematopoietic Stem Cell Transplantation, but a Role for Candida in Acute Graft-Versus-Host Disease.
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van der Velden, Walter J.F.M., primary, Plantinga, Theo, additional, Feuth, Ton, additional, Donnelly, Peter, additional, Netea, Mihai, additional, and Blijlevens, Nicole N.A., additional
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- 2009
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49. Clofarabine added to intensive treatment in adult patients with newly diagnosed ALL: the HOVON-100 trial
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Rijneveld, Anita W., van der Holt, Bronno, de Weerdt, Okke, Biemond, Bart J., van de Loosdrecht, Arjen A., van der Wagen, Lotte E., Bellido, Mar, van Gelder, Michel, van der Velden, Walter J.F.M., Selleslag, Dominik, van Lammeren-Venema, Daniëlle, Halkes, Constantijn J.M., Fijnheer, Rob, Havelange, Violaine, van Sluis, Geerte L., Legdeur, Marie-Cecile, Deeren, Dries, Gadisseur, Alain, Sinnige, Harm A.M., Breems, Dimitri A., Jaspers, Aurélie, Legrand, Ollivier, Terpstra, Wim E., Boersma, Rinske S., Mazure, Dominiek, Triffet, Agnes, Tick, Lidwine W., Beel, Karolien, Maertens, Johan A., Beverloo, H. Berna, Bakkus, Marleen, Homburg, Christa H.E., de Haas, Valerie, van der Velden, Vincent H.J., and Cornelissen, Jan J.
- Abstract
Clofarabine (CLO) is a nucleoside analogue with efficacy in relapsed/refractory acute lymphoblastic leukemia (ALL). This randomized phase III study aimed to evaluate whether CLO added to induction and consolidation would improve outcome in adults with newly diagnosed ALL.Treatment for younger (18-40 years) patients consisted of a pediatric inspired protocol and for older patients (41-70 years) of a semi-intensive protocol was used. 340 patients were randomized. After a median follow up of 70 months,5-year EFS was 50% and 53% for arm A and B (CLO arm). For patients ≤40 years, EFS was 58% vs 65% in arm A vs B, while in patients >40 years EFS was 43% in both arms. CR rate was 89% in both arms and similar in younger and older patients.Minimal residual disease (MRD) was assessedin 200 patients (60%).Fifty-fourof 76evaluable patients(71%) were MRD negative after consolidation 1 in arm A vs 75/81 (93%) in arm B (p=0.001). Seventy (42%) patients proceeded to allogeneic hematopoietic stemcell transplantation in both arms. Five years OS was similar in both arms, 60% vs 61%. Among patients achieving CR, relapse rates were 28% and 24%, and non-relapse mortality was 16% vs 17% after CR. CLO treated patients experienced more serious adverse events, moreinfections, and more often went off-protocol. This was most pronounced in older patients. We conclude that, despite a higher rate of MRD-negativity, addition of CLO does not improve outcome in adults with ALL, which might be due to increased toxicity.The trial is registered at www.trialregister.nl as NTR2004.
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- 2021
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50. No Impact of Dectin-1 Polymorphism Y238X On the Outcome of Hematopoietic Stem Cell Transplantation, but a Role for Candidain Acute Graft-Versus-Host Disease.
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van der Velden, Walter J.F.M., Plantinga, Theo, Feuth, Ton, Donnelly, Peter, Netea, Mihai, and Blijlevens, Nicole N.A.
- Abstract
Abstract 4498
- Published
- 2009
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