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Your search keyword '"van der Eijk, A.A."' showing total 23 results
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23 results on '"van der Eijk, A.A."'

7. The Usefulness of Aqueous Fluid Analysis for Epstein-Barr Virus in Patients with Uveitis.

Author

Groen-Hakan, F., Van Der Eijk, A.A., and Rothova, A.

Subjects
*EPSTEIN-Barr virus, *UVEITIS, *DNA analysis, *AQUEOUS humor, *DNA, *RETROSPECTIVE studies, *VIRAL eye infections, *ENZYME-linked immunosorbent assay, *POLYMERASE chain reaction, *EPSTEIN-Barr virus diseases
Abstract

Purpose: To determine characteristics of patients with laboratory findings indicative of intraocular Epstein-Barr-virus (EBV) infection and to establish the usefulness of the laboratory analysis in patients with uveitis.Methods: Retrospective study of patients who underwent diagnostic aqueous fluid analysis. Diverse demographic data of patients were registered.Results: EBV-PCR tested positive in 3/201 (1%) and EBV-GWC in 22/245 (9%). The prevalence of immunosuppression was similar in EBV positive (by PCR/GWC) and EBV negative patients (7/25; 28% vs. 50/272;18%, P = 0.29). Out of all 22 EBV-GWC positive patients, GWC was between 3 and 10 in 91%. In total, 14 patients had laboratory results indicating only EBV infection. Patients without an alternative explanation for uveitis (6/14; 43%) had a chronic recurrent course and good visual prognosis.Conclusion: Low EBV-GWC values combined with multiple positive GWC and/or PCR for other infectious agents. Intraocular assessment for EBV in the initial examination of uveitis patients has limited value. [ABSTRACT FROM AUTHOR]

Published
2020
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12. P670 POST-INFECTIOUS PERIPHERAL NERVOUS SYSTEM DISORDERS AND HEPATITIS E VIRUS

Author

Madden, R.G., primary, van den Berg, B., additional, van Eijk, J.J.J., additional, van der Eijk, A.A., additional, Hunter, J.G., additional, Tio-Gillen, A.P., additional, Reimerink, J., additional, Bendall, R.P., additional, Pas, S.D., additional, Ellis, V., additional, van Alfen, N., additional, Beynon, L., additional, Southwell, L., additional, McLean, B., additional, van Engelen, B.G.M., additional, Jacobs, B.C., additional, and Dalton, H.R., additional

Published
2014
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23. Doctor to patient transmission of hepatitis B virus: implications of HBV DNA levels and potential new solutions

Author

Buster, E.H.C.J., van der Eijk, A.A., and Schalm, S.W.

Subjects
*HEPATITIS B, *MEDICAL care, *INFECTION, *DNA
Abstract

Hepatitis B virus (HBV)-infected health care workers (HCWs) can infect patients undergoing exposure prone procedures. Until now reviews have focused on the problem of the HBeAg-positive HCWs. After transmission of HBV by HBeAg-negative surgeons, the focus of Public Health Policy in the UK and the Netherlands has changed from HBeAg status to serum HBV DNA level. Viral load and the volume of blood transmitted determine the transmission risk of HBV. We have estimated the number of infectious particles transmitted by needlesticks, in comparison with those attributed in maternal–fetal transfusion. The blood volume transmitted by needlestick is roughly 1–30% of that of delivery. As vertical transmission with maternal HBV DNA levels below 107 g Eq./ml is rarely documented, HBV transmission by needlesticks is, according to our assumptions, unlikely to occur with HBV DNA levels below 107 g Eq./ml.Sera of transmitting HCWs contained HBV DNA levels between 5.0×109 and 6.35×104 g Eq./ml. Interpretation of these levels is hampered as the sera were taken at least 3 months after transmission. To prevent both loss of expertise and nosocomial infection, highly viremic HCWs can be offered antiviral therapy. Lamivudine and alpha-interferon can now be complemented with adefovir, tenofovir and entecavir to provide effective new therapies for chronic HBV-infected HCWs. [Copyright &y& Elsevier]

Published
2003
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