490 results on '"van de Sluis, Bart"'
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2. Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice
3. THU-224 CRISPR/Cas9-mediated somatic gene editing in adult mice reveals hepatic KLB as a regulator of bile acid synthesis and hepatic lipid metabolism
4. T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
5. Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism
6. Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile
7. The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis
8. Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD)
9. Proteinuria converts hepatic heparan sulfate to an effective proprotein convertase subtilisin kexin type 9 enzyme binding partner
10. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
11. Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid
12. Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes
13. Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice
14. Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome
15. VLDL Biogenesis and Secretion: It Takes a Village
16. Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice
17. Protection against high-fat diet induced obesity, dyslipidaemia, and fatty liver in a preclinical setting
18. Hepatic Retromer is critical for systemic cholesterol homeostasis via shaping the endo-lysosomal organization
19. SMLR1 is a novel player in chylomicron metabolism
20. GPR146 and HDL metabolism
21. The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
22. Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans
23. The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice
24. Mitochondrial DNA methylation in metabolic associated fatty liver disease
25. Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain
26. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism
27. COMMD1 in Copper Homeostasis
28. List of Contributors
29. Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet
30. Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia
31. Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain
32. Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way
33. Senescent cells in the development of cardiometabolic disease
34. A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis
35. Erich4 is Not Involved in the Assembly and Secretion of Intestinal Lipoproteins
36. Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins
37. Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway
38. Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH
39. Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion
40. Variants in theGPR146Gene Are Associated With a Favorable Cardiometabolic Risk Profile
41. Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor–Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans
42. The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking
43. Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism
44. IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner
45. FRI-549-YI Hepatic loss of the endosomal sorting complex Retromer delays postnatal liver maturation and increases hepatocellular proliferation
46. T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
47. Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome
48. Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile.
49. A liver‐specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis
50. News on the molecular regulation and function of hepatic low-density lipoprotein receptor and LDLR-related protein 1
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