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1. Clinical outcomes of uninterrupted embryo culture with or without time-lapse-based embryo selection versus interrupted standard culture (SelecTIMO): a three-armed, multicentre, double-blind, randomised controlled trial

Author

Kieslinger, D C, Vergouw, C G, Ramos, L, Arends, B, Curfs, M H J M, Slappendel, E, Kostelijk, E H, Pieters, M H E C, Consten, D, Verhoeven, M O, Besselink, D E, Broekmans, F, Cohlen, B J, Smeenk, J M J, Mastenbroek, S, de Koning, C H, van Kasteren, Y M, Moll, E, van Disseldorp, J, Brinkhuis, E A, Kuijper, E A M, van Baal, W M, van Weering, H G I, van der Linden, P J Q, Gerards, M H, Bossuyt, P M, van Wely, M, and Lambalk, C B

Published
2023
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2. Transcatheter aortic valve implantation amid the COVID-19 pandemic: a nationwide analysis of the first COVID-19 wave in the Netherlands

Author

Rooijakkers, M. J. P., Li, W. W. L., Stens, N. A., Vis, M. M., Tonino, P. A. L., Timmers, L., Van Mieghem, N. M., den Heijer, P., Kats, S., Stella, P. R., Roolvink, V., van der Werf, H. W., Stoel, M. G., Schotborgh, C. E., Amoroso, G., Porta, F., van der Kley, F., van Wely, M. H., Gehlmann, H., van Garsse, L. A. F. M., Geuzebroek, G. S. C., Verkroost, M. W. A., Mourisse, J. M., Medendorp, N. M., and van Royen, N.

Published
2022
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3. Oil-based versus water-based contrast media for hysterosalpingography in infertile women of advanced age, with ovulation disorders or a high risk for tubal pathology: study protocol of a randomized controlled trial (H2Oil2 study)

Author

Rosielle, K., Kamphuis, D., van Welie, N., Roest, I., Mozes, A., van Santbrink, E. J. P., van de Laar, T., Hooker, A. B., Huppelschoten, A. G., Li, W., Bongers, M. Y., Stoker, J., van Wely, M., Koks, C., Lambalk, C. B., Hemingway, A., Mol, B. W. J., Dreyer, K., and Mijatovic, V.

Published
2022
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5. Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study

Author

Abou-Setta, Ahmed M., Aguilera, Juan J., AlAhwany, Hisham, Atanda, Oluseyi O.A., Balkenende, Eva M.E., Barnhart, Kurt T., Beebeejaun, Yusuf, Black, Megan, Chambers, Georgina M., Chughtai, Abrar A., Crosby, Javier A., Cuevas-Sáiz, Irene, Curtis, Cate, D'Angelo, Arianna, Dubois, Danielle D., Duckitt, Kirsten, Encinas, Carlos, Gerval, Marie-Odile, Giang, Nhu H., Gibreel, Ahmed, Gingel, Lynda J., Glanville, Elizabeth J., Glujovsky, Demian, Granne, Ingrid, Griesinger, Georg, Gupta Repromed, Devashana, Hamzehgardeshi, Zeinab, Hirsch, Martin, Horton, Marcos, Jain, Shikha, Jansa Perez, Marta, Jones, Claire A., Kamath, Mohan S., Knijnenburg, José, Kostova, Elena, La Marca, Antonio, Khac Le, Tien, Leader, Arthur, Leeviers, Brigitte, Li Chinese, Jian, Loto, Olabisi M., Marks, Karen L., Martinez-Vazquez, Rodrigo M., McTavish, Alison R., Mills, David J., Nair, Raju R., Thi Phuong Nguyen, Dung, Otter, Anne-Sophie, Pacey, Allan A., Rautakallio-Hokkanen, Satu, Sadler, Lynn C., Sagle, Peggy, Schwarze, Juan-Enrique, Shapiro, Heather M., Simpson, Joe L., Siristatidis, Charalampos S., Sood, Akanksha, Strawbridge, Catherine, Torrance, Helen L., Tu Tran, Cam, Votteler, Emma L., Wang, Chi Chiu, Watson, Andrew, Yossry, Menem, Duffy, J.M.N., Bhattacharya, S., Bofill, M., Collura, B., Curtis, C., Evers, J.L.H., Giudice, L.C., Farquharson, R.G., Franik, S., Hickey, M., Hull, M.L., Jordan, V., Khalaf, Y., Legro, R.S., Lensen, S., Mavrelos, D., Mol, B.W., Niederberger, C., Ng, E.H.Y., Puscasiu, L., Repping, S., Sarris, I., Showell, M., Strandell, A., Vail, A., van Wely, M., Vercoe, M., Vuong, N.L., Wang, A.Y., Wang, R., Wilkinson, J., Youssef, M.A., and Farquhar, C.M.

Published
2021
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6. Top 10 priorities for future infertility research: an international consensus development study

Author

AlAhwany, Hisham, Balaban, Ofra, Beebeejaun, Yusuf, Boivin, Jacky, Bosteels, Jan J.A., D’Angelo, Arianna, Dann, Leona F., De Jonge, Christopher J., du Mez, Elyce, Ferriani, Rui A., Gerval, Marie-Odile, Gingel, Lynda J., Greenblatt, Ellen M., Hartshorne, Geraldine, Helliwell, Charlie, Helliwell, Charlotte, Hughes, Lynda J., Jo, Junyoung, Jovanović, Jelena, Kiesel, Ludwig, Kietpeerakool, Chumnan, Kostova, Elena, Kucuk, Tansu, Lawrence, Robyn L., Lee, Nicole, Lindemann, Katy E., Loto, Olabisi M., Lutjen, Peter J., MacKinven, Michelle, Mascarenhas, Mariano, McLaughlin, Helen, Mills, David J., Mourad, Selma M., Nguyen, Linh K., Norman, Robert J., Olic, Maja, Overfield, Kristine L., Parker-Harris, Maria, Ramos, David G., Rendulic, Aleksandra, Repping, Sjoerd, Rizzo, Roberta, Salacone, Pietro, Saunders, Catherine H., Sengupta, Rinku, Sfontouris, Ioannis A., Silverman, Natalie R., Torrance, Helen L., Uphoff, Eleonora P., Wakeman, Sarah A., Wischmann, Tewes, Woodward, Bryan J., Youssef, Mohamed A., Duffy, J.M.N., Adamson, G.D., Benson, E., Bhattacharya, S., Bofill, M., Brian, K., Collura, B., Curtis, C., Evers, J.L.H., Farquharson, R.G., Fincham, A., Franik, S., Giudice, L.C., Glanville, E., Hickey, M., Horne, A.W., Hull, M.L., Johnson, N.P., Jordan, V., Khalaf, Y., Knijnenburg, J.M.L., Legro, R.S., Lensen, S., MacKenzie, J., Mavrelos, D., Mol, B.W., Morbeck, D.E., Nagels, H., Ng, E.H.Y., Niederberger, C., Otter, A.S., Puscasiu, L., Rautakallio-Hokkanen, S., Sadler, L., Sarris, I., Showell, M., Stewart, J., Strandell, A., Strawbridge, C., Vail, A., van Wely, M., Vercoe, M., Vuong, N.L., Wang, A.Y., Wang, R., Wilkinson, J., Wong, K., Wong, T.Y., and Farquhar, C.M.

Published
2021
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7. Developing a core outcome set for future infertility research: an international consensus development study

Author

Abou-Setta, Ahmed M., Aguilera, Juan J., Atanda, Oluseyi O.A., Balkenende, Eva M.E., Barnhart, Kurt T., Beebeejaun, Yusuf, Bhattacharya, Sohinee, Black, Megan, Bofill, Magdalena, Chambers, Georgina M., Chughtai, Abrar A., Crosby, Javier A., Cuevas-Sáiz, Irene, D'Angelo, Arianna, Dubois, Danielle D., Duckitt, Kirsten, Encinas, Carlos, Fincham, Anita, Gerval, Marie-Odile, Giang, Nhu H., Gibreel, Ahmed, Gingel, Lynda J., Glanville, Elizabeth J., Glujovsky, Demian, Granne, Ingrid, Griesinger, Georg, Gupta, Devashana, Hamzehgardeshi, Zeinab, Hickey, Martha, Hirsch, Martin, Horton, Marcos, Hull, M. Louise, Jain, Shikha, Jansa Perez, Marta, Jones, Claire A., Jordan, Vanessa, Kamath, Mohan S., Kostova, Elena, La Marca, Antonio, Khac Le, Tien, Leader, Arthur, Li, Jian, Loto, Olabisi M., Marks, Karen L., McTavish, Alison R., Mills, David J., Nair, Raju R., Thi Phuong Nguyen, Dung, Pacey, Allan A., Sadler, Lynn C., Sagle, Peggy, Schwarze, Juan-Enrique, Shapiro, Heather M., Showell, Marian, Siristatidis, Charalampos S., Sood, Akanksha, Tu Tran, Cam, Votteler, Emma L., Wang, Chi Chiu, Watson, Andrew, Yossry, Menem, Duffy, J.M.N., AlAhwany, H., Bhattacharya, S., Collura, B., Curtis, C., Evers, J.L.H., Farquharson, R.G., Franik, S., Giudice, L.C., Khalaf, Y., Knijnenburg, J.M.L., Leeners, B., Legro, R.S., Lensen, S., Vazquez-Niebla, J.C., Mavrelos, D., Mol, B.W.J., Niederberger, C., Ng, E.H.Y., Otter, A.S., Puscasiu, L., Rautakallio-Hokkanen, S., Repping, S., Sarris, I., Simpson, J.L., Strandell, A., Strawbridge, C., Torrance, H.L., Vail, A., van Wely, M., Vercoe, M.A., Vuong, N.L., Wang, A.Y., Wang, R., Wilkinson, J., Youssef, M.A., and Farquhar, C.M.

Published
2021
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12. Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: Alternative versus standard stimulation protocols; the study protocol of the STIM-trial

Author

Dahhan, T., Balkenende, E.M.E., Beerendonk, C.C.M., Fleischer, K., Stoop, D., Bos, A.M.E., Lambalk, C.B., Schats, R., van Golde, R.J.T., Schipper, I., Louwé, L.A., Cantineau, A.E.P., Smeenk, J.M.J., de Bruin, J.P., Reddy, N., Kopeika, Y., van der Veen, F., van Wely, M., Linn, S.C., and Goddijn, M.

Published
2017
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14. P-293 Is time-lapse monitoring a safe alternative? Obstetric and neonatal outcomes of a multicenter randomized controlled trial

Author

Kieslinger, D C, primary, Vergouw, C G, additional, Von Estorff, F, additional, Ramos, L, additional, Arends, B, additional, Curfs, M H J M, additional, Slappendel, E, additional, Kostelijk, E H, additional, Pieters, M H E C, additional, Consten, D, additional, Verhoeven, M O, additional, Besselink, D E, additional, Broekmans, F, additional, Cohlen, B J, additional, Smeenk, J M J, additional, Mastenbroek, S, additional, De Koning, C H, additional, Van Kasteren, Y M, additional, Moll, E, additional, Van Disseldorp, J, additional, Brinkhuis, E A, additional, Kuijper, E A M, additional, Van Baal, W M, additional, Van Weering, H G I, additional, Van der Linden, P J Q, additional, Gerards, M H, additional, Bossuyt, P M, additional, Van Wely, M, additional, and Lambalk, C B, additional

Published
2023
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16. O-192 Does tubal flushing by hysterosalpingo-foam sonography and hysterosalpingography affect tubal patency? Results from a randomized clinical trial

Author

Kamphuis, D, primary, Van Welie, N, additional, Van Hooff, M, additional, Verhoeve, H, additional, De Bruin, J P, additional, Mol, F, additional, Van Baal, M, additional, Van de Laar, B, additional, Lambalk, C, additional, Stoker, J, additional, Van Wely, M, additional, Bossuyt, P, additional, Mol, B, additional, Dreyer, K, additional, and Mijatovic, V, additional

Published
2023
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17. Clinical outcomes of uninterrupted embryo culture with or without time-lapse-based embryo selection versus interrupted standard culture (SelecTIMO): a three-armed, multicentre, double-blind, randomised controlled trial

Author

Research UMC Utrecht, Functieafdeling Fertiliteit/IVF, MS VPG/Gynaecologie, Child Health, Kieslinger, D. C., Vergouw, C. G., Ramos, L., Arends, B., Curfs, M. H.J.M., Slappendel, E., Kostelijk, E. H., Pieters, M. H.E.C., Consten, D., Verhoeven, M. O., Besselink, D. E., Broekmans, F., Cohlen, B. J., Smeenk, J. M.J., Mastenbroek, S., de Koning, C. H., van Kasteren, Y. M., Moll, E., van Disseldorp, J., Brinkhuis, E. A., Kuijper, E. A.M., van Baal, W. M., van Weering, H. G.I., van der Linden, P. J.Q., Gerards, M. H., Bossuyt, P. M., van Wely, M., Lambalk, C. B., Research UMC Utrecht, Functieafdeling Fertiliteit/IVF, MS VPG/Gynaecologie, Child Health, Kieslinger, D. C., Vergouw, C. G., Ramos, L., Arends, B., Curfs, M. H.J.M., Slappendel, E., Kostelijk, E. H., Pieters, M. H.E.C., Consten, D., Verhoeven, M. O., Besselink, D. E., Broekmans, F., Cohlen, B. J., Smeenk, J. M.J., Mastenbroek, S., de Koning, C. H., van Kasteren, Y. M., Moll, E., van Disseldorp, J., Brinkhuis, E. A., Kuijper, E. A.M., van Baal, W. M., van Weering, H. G.I., van der Linden, P. J.Q., Gerards, M. H., Bossuyt, P. M., van Wely, M., and Lambalk, C. B.

Published
2023

19. Effect of levothyroxine on live birth rate in euthyroid women with recurrent miscarriage and TPO antibodies (T4-LIFE study)

Author

Vissenberg, R., van Dijk, M.M., Fliers, E., van der Post, J.A.M., van Wely, M., Bloemenkamp, K.W.M., Hoek, A., Kuchenbecker, W.K., Verhoeve, H.R., Scheepers, H.C.J., Rombout-de Weerd, S., Koks, C., Zwart, J.J., Broekmans, F., Verpoest, W., Christiansen, O.B., Post, M., Papatsonis, D.N.M., Verberg, M.F.G., Sikkema, J., Mol, B.W., Bisschop, P.H., and Goddijn, M.

Published
2015
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20. Current MitraClip experience, safety and feasibility in the Netherlands

Author

Rahhab, Z., Kortlandt, F. A., Velu, J. F., Schurer, R. A. J., Delgado, V., Tonino, P., Boven, A. J., Van den Branden, B. J. L., Kraaijeveld, A. O., Voskuil, M., Hoorntje, J., van Wely, M., van Houwelingen, K., Bleeker, G. B., Rensing, B., Kardys, I., Baan jr., J., Van der Heyden, J. A. S., and Van Mieghem, N. M.

Published
2017
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24. Prevention of multiple pregnancies in couples with unexplained or mild male subfertility : randomised controlled trial of in vitro fertilisation with single embryo transfer or in vitro fertilisation in modified natural cycle compared with intrauterine insemination with controlled ovarian hyperstimulation

Author

Bensdorp, A J, Tjon-Kon-Fat, R I, Bossuyt, P M M, Koks, C A M, Oosterhuis, G J E, Hoek, A, Hompes, P G A, Broekmans, F J M, Verhoeve, H R, de Bruin, J P, van Golde, R, Repping, S, Cohlen, B J, Lambers, M D A, van Bommel, P F, Slappendel, E, Perquin, D, Smeenk, J M, Pelinck, M J, Gianotten, J, Hoozemans, D A, Maas, J W M, Eijkemans, M J C, van der Veen, F, Mol, B W J, and van Wely, M

Published
2015

26. The randomised uterine septum transsection trial (TRUST): design and protocol

Author

Rikken, J. F. W., Kowalik, C. R., Emanuel, M. H., Bongers, M. Y., Spinder, T., de Kruif, J. H., Bloemenkamp, K. W. M., Jansen, F. W., Veersema, S., Mulders, A. G. M. G. J., Thurkow, A. L., Hald, K., Mohazzab, A., Khalaf, Y., Clark, T. J., Farrugia, M., van Vliet, H. A., Stephenson, M. S., van der Veen, F., van Wely, M., Mol, B. W. J., and Goddijn, M.

Published
2018
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27. Expectant management versus IUI in unexplained subfertility and a poor pregnancy prognosis (EXIUI study): a randomized controlled trial

Author

Wessel, J A, primary, Mochtar, M H, additional, Besselink, D E, additional, Betjes, H, additional, de Bruin, J P, additional, Cantineau, A E P, additional, Groenewoud, E R, additional, Hooker, A B, additional, Lambalk, C B, additional, Kwee, J, additional, Kaaijk, E M, additional, Louwé, L A, additional, Maas, J W M, additional, Mol, B W J, additional, van Rumste, M M E, additional, Traas, M A F, additional, Goddijn, M, additional, van Wely, M, additional, and Mol, F, additional

Published
2022
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28. Assessment of paravalvular regurgitation after transcatheter aortic valve replacement by hemodynamic measurements and cardiac magnetic resonance (APPOSE trial)

Author

Rooijakkers, M J P, primary, Stens, N A, additional, Van Wely, M H, additional, Van Der Wulp, K, additional, Rodwell, L, additional, Gehlmann, H, additional, Van Garsse, L A F M, additional, Geuzebroek, G S C, additional, Verkroost, M W A, additional, Habets, J, additional, El Messaoudi, S, additional, Thijssen, D H J, additional, Nijveldt, R, additional, and Van Royen, N, additional

Published
2022
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30. Ovarian Stimulation Strategies for Intrauterine Insemination in Couples with Unexplained Infertility - A Systematic Review and Individual Participant Data Meta-analysis

Author

WESSEL, J.A., primary, DANHOF, N.A., additional, VAN EEKELEN, R., additional, DIAMOND, M.P., additional, LEGRO, R.S., additional, PEERAER, K., additional, ERDEM, M., additional, DANKERT, T., additional, ECOCHARD, R., additional, MOL, B.W., additional, VAN WELY, M., additional, MOCHTAR, M.H., additional, and WANG, R., additional

Published
2022
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37. O-188 Tubal testing with Hysterosalpingo-foam sonography (HyFoSy) versus hysterosalpingography (HSG) during the fertility work-up: a cost-effectiveness analysis alongside a randomised controlled trial

Author

Kamphuis, D, primary, Van Eekelen, R, additional, Van Welie, N, additional, Dreyer, K, additional, Van Rijswijk, J, additional, Van Hooff, M.H.A, additional, De Bruin, J.P, additional, Verhoeve, H.R, additional, Mol, F, additional, Lambalk, C.B, additional, Stoker, J.S, additional, Van Wely, M, additional, Bossuyt, P.M.M, additional, Mol, B.W.J, additional, and Mijatovic, V, additional

Published
2022
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41. O-003 The SelecTIMO study - clinical outcomes of uninterrupted embryo culture with or without time-lapse based embryo selection versus interrupted standard culture: a randomized controlled trial

Author

Kieslinger, D C, primary, Vergouw, C G, additional, Ramos, L, additional, Arends, B, additional, Curfs, M H J M, additional, Slappendel, E, additional, Kostelijk, E H, additional, Pieters, M H E C, additional, Consten, D, additional, Verhoeven, M O, additional, Besselink, D E, additional, Broekmans, F, additional, Cohlen, B J, additional, Smeenk, J M J, additional, Mastenbroek, S, additional, De Koning, C H, additional, Van Kasteren, Y M, additional, Moll, E, additional, Van Disseldorp, J, additional, Brinkhuis, E A, additional, Kuijper, E A M, additional, Van Baal, W M, additional, Van Weering, H G I, additional, Van der Linden, P J Q, additional, Gerards, M H, additional, Bossuyt, P M, additional, Van Wely, M, additional, and Lambalk, C B, additional

Published
2022
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47. O-021 Levothyroxine in Euthyroid Thyroid Peroxidase Antibody positive Women with Recurrent Pregnancy Loss: a multicentre, randomised, double-blind trial (T4LIFE trial)

Author

Van Dijk, M, primary, Vissenberg, R, additional, Fliers, E, additional, Van der Post, J, additional, Van der Hoorn, M L, additional, De Weerd, S, additional, Verpoest, W, additional, Christiansen, O, additional, De Bruin, J P, additional, Papatsonis, D, additional, Torrance, H, additional, Van Wely, M, additional, Bisschop, P, additional, and Goddijn, M, additional

Published
2022
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50. SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis

Author

Allotey, J, Chatterjee, S, Kew, T, Gaetano, A, Stallings, E, Fernández-García, S, Yap, M, Sheikh, J, Lawson, H, Coomar, D, Dixit, A, Zhou, D, Balaji, R, Littmoden, M, King, Y, Debenham, L, Llavall, AC, Ansari, K, Sandhu, G, Banjoko, A, Walker, K, O'Donoghue, K, van Wely, M, van Leeuwen, E, Kostova, E, Kunst, H, Khalil, A, Brizuela, V, Broutet, N, Kara, E, Kim, CR, Thorson, A, Oladapo, OT, Zamora, J, Bonet, M, Mofenson, L, Thangaratinam, S, and PregCOV-19 Living Systematic Review Consortium

Abstract

OBJECTIVES: To assess the rates of SARS-CoV-2 positivity in babies born to mothers with SARS-CoV-2 infection, the timing of mother-to-child transmission and perinatal outcomes, and factors associated with SARS-CoV-2 status in offspring. DESIGN: Living systematic review and meta-analysis. DATA SOURCES: Major databases between 1 December 2019 and 3 August 2021. STUDY SELECTION: Cohort studies of pregnant and recently pregnant women (including after abortion or miscarriage) who sought hospital care for any reason and had a diagnosis of SARS-CoV-2 infection, and also provided data on offspring SARS-CoV-2 status and risk factors for positivity. Case series and case reports were also included to assess the timing and likelihood of mother-to-child transmission in SARS-CoV-2 positive babies. DATA EXTRACTION: Two reviewers independently extracted data and assessed study quality. A random effects model was used to synthesise data for rates, with associations reported using odds ratios and 95% confidence intervals. Narrative syntheses were performed when meta-analysis was inappropriate. The World Health Organization classification was used to categorise the timing of mother-to-child transmission (in utero, intrapartum, early postnatal). RESULTS: 472 studies (206 cohort studies, 266 case series and case reports; 28 952 mothers, 18 237 babies) were included. Overall, 1.8% (95% confidence interval 1.2% to 2.5%; 140 studies) of the 14 271 babies born to mothers with SARS-CoV-2 infection tested positive for the virus with reverse transcriptase polymerase chain reaction (RT-PCR). Of the 592 SARS-CoV-2 positive babies with data on the timing of exposure and type and timing of tests, 14 had confirmed mother-to-child transmission: seven in utero (448 assessed), two intrapartum (18 assessed), and five during the early postnatal period (70 assessed). Of the 800 SARS-CoV-2 positive babies with outcome data, 20 were stillbirths, 23 were neonatal deaths, and eight were early pregnancy losses; 749 babies were alive at the end of follow-up. Severe maternal covid-19 (odds ratio 2.4, 95% confidence interval 1.3 to 4.4), maternal death (14.1, 4.1 to 48.0), maternal admission to an intensive care unit (3.5, 1.7 to 6.9), and maternal postnatal infection (5.0, 1.2 to 20.1) were associated with SARS-CoV-2 positivity in offspring. Positivity rates using RT-PCR varied between regions, ranging from 0.1% (95% confidence interval 0.0% to 0.3%) in studies from North America to 5.7% (3.2% to 8.7%) in studies from Latin America and the Caribbean. CONCLUSION: SARS-CoV-2 positivity rates were found to be low in babies born to mothers with SARS-CoV-2 infection. Evidence suggests confirmed vertical transmission of SARS-CoV-2, although this is likely to be rare. Severity of maternal covid-19 appears to be associated with SARS-CoV-2 positivity in offspring. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020178076. READERS' NOTE: This article is a living systematic review that will be updated to reflect emerging evidence. Updates may occur for up to two years from the date of original publication.

Published
2022

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