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2. Tyrosine Metabolism

Author

van Spronsen, Francjan J., Burlina, Alberto, Dionisi Vici, Carlo, Blau, Nenad, editor, Dionisi Vici, Carlo, editor, Ferreira, Carlos R., editor, Vianey-Saban, Christine, editor, and van Karnebeek, Clara D. M., editor

Published
2022
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7. High-dose ERT, rituximab, and early HSCT in an infant with Wolman’s disease

Author

MS Algemene Pediatrie Onderzoek 2, UMC Krant, SCT patientenzorg, Child Health, Infection & Immunity, Regenerative Medicine and Stem Cells, Metabole ziekten patientenzorg, Eskandari, Siawosh K., Revenich, Elisabeth G.M., Pot, Dirk J., de Boer, Foekje, Bierings, Marc, van Spronsen, Francjan J., van Hasselt, Peter M., Lindemans, Caroline A., Lubout, Charlotte M.A., MS Algemene Pediatrie Onderzoek 2, UMC Krant, SCT patientenzorg, Child Health, Infection & Immunity, Regenerative Medicine and Stem Cells, Metabole ziekten patientenzorg, Eskandari, Siawosh K., Revenich, Elisabeth G.M., Pot, Dirk J., de Boer, Foekje, Bierings, Marc, van Spronsen, Francjan J., van Hasselt, Peter M., Lindemans, Caroline A., and Lubout, Charlotte M.A.

Published
2024

8. Efficacy and safety of sapropterin before and during pregnancy: Final analysis of the Kuvan® Adult Maternal Paediatric European Registry (KAMPER) maternal and Phenylketonuria Developmental Outcomes and Safety (PKUDOS) PKU‐MOMs sub‐registries

Author

Feillet, François, Ficicioglu, Can, Lagler, Florian B., Longo, Nicola, Muntau, Ania C., Burlina, Alberto, Trefz, Friedrich K., van Spronsen, Francjan J., Arnoux, Jean‐Baptiste, Lindstrom, Kristin, Lilienstein, Joshua, Clague, Gillian E., Rowell, Richard, and Burton, Barbara K.

Abstract

Infants born to mothers with phenylketonuria (PKU) may develop congenital abnormalities because of elevated phenylalanine (Phe) levels in the mother during pregnancy. Maintenance of blood Phe levels between 120 and 360 μmol/L reduces risks of birth defects. Sapropterin dihydrochloride helps maintain blood Phe control, but there is limited evidence on its risk–benefit ratio when used during pregnancy. Data from the maternal sub‐registries—KAMPER (NCT01016392) and PKUDOS (NCT00778206; PKU‐MOMs sub‐registry)—were collected to assess the long‐term safety and efficacy of sapropterin in pregnant women in a real‐life setting. Pregnancy and infant outcomes, and the safety of sapropterin were assessed. Final data from 79 pregnancies in 57 women with PKU are reported. Sapropterin dose was fairly constant before and during pregnancy, with blood Phe levels maintained in the recommended target range during the majority (82%) of pregnancies. Most pregnancies were carried to term, and the majority of liveborn infants were reported as 'normal' at birth. Few adverse and serious adverse events were considered related to sapropterin, with these occurring in participants with high blood Phe levels. This report represents the largest population of pregnant women with PKU exposed to sapropterin. Results demonstrate that exposure to sapropterin during pregnancy was well‐tolerated and facilitated maintenance of blood Phe levels within the target range, resulting in normal delivery. This critical real‐world data may facilitate physicians and patients to make informed treatment decisions about using sapropterin in pregnant women with PKU and in women of childbearing age with PKU who are responsive to sapropterin. [ABSTRACT FROM AUTHOR]

Published
2024
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11. A False-Negative Newborn Screen for Tyrosinemia Type 1—Need for Re-Evaluation of Newborn Screening with Succinylacetone

Author

Dijkstra, Allysa M., primary, Evers-van Vliet, Kimber, additional, Heiner-Fokkema, M. Rebecca, additional, Bodewes, Frank A. J. A., additional, Bos, Dennis K., additional, Zsiros, József, additional, van Aerde, Koen J., additional, Koop, Klaas, additional, van Spronsen, Francjan J., additional, and Lubout, Charlotte M. A., additional

Published
2023
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13. Phenylketonuria

Author

van Spronsen, Francjan J., Blau, Nenad, Harding, Cary, Burlina, Alberto, Longo, Nicola, and Bosch, Annet M.

Published
2021
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16. A Delphi Survey Study to Formulate Statements on the Treatability of Inherited Metabolic Disorders to Decide on Eligibility for Newborn Screening

Author

Veldman, Abigail, primary, Kiewiet, M. B. Gea, additional, Westra, Dineke, additional, Bosch, Annet M., additional, Brands, Marion M. G., additional, de Coo, René I. F. M., additional, Derks, Terry G. J., additional, Fuchs, Sabine A., additional, van den Hout, Johanna. M. P., additional, Huidekoper, Hidde H., additional, Kluijtmans, Leo A. J., additional, Koop, Klaas, additional, Lubout, Charlotte M. A., additional, Mulder, Margaretha F., additional, Panis, Bianca, additional, Rubio-Gozalbo, M. Estela, additional, de Sain-van der Velden, Monique G., additional, Schaefers, Jaqueline, additional, Schreuder, Andrea B., additional, Visser, Gepke, additional, Wevers, Ron A., additional, Wijburg, Frits A., additional, Heiner-Fokkema, M. Rebecca, additional, and van Spronsen, Francjan J., additional

Published
2023
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18. What Is the Best Blood Sampling Time for Metabolic Control of Phenylalanine and Tyrosine Concentrations in Tyrosinemia Type 1 Patients?

Author

van Dam, Esther, Daly, Anne, Venema-Liefaard, Gineke, van Rijn, Margreet, Derks, Terry G. J., McKiernan, Patrick J., Rebecca Heiner-Fokkema, M., MacDonald, Anita, van Spronsen, Francjan J., Baumgartner, Matthias R., Series editor, Patterson, Marc, Series editor, Rahman, Shamima, Series editor, Peters, Verena, Series editor, Morava, Eva, Editor-in-chief, Zschocke, Johannes, Series editor, and Baumgartner, Matthias, editor

Published
2017
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19. Reliable Diagnosis of Carnitine Palmitoyltransferase Type IA Deficiency by Analysis of Plasma Acylcarnitine Profiles

Author

Heiner-Fokkema, M. Rebecca, Vaz, Frédéric M., Maatman, Ronald, Kluijtmans, Leo A. J., van Spronsen, Francjan J., Reijngoud, Dirk-Jan, Baumgartner, Matthias R., Series editor, Patterson, Marc, Series editor, Rahman, Shamima, Series editor, Peters, Verena, Series editor, Morava, Eva, Editor-in-chief, Zschocke, Johannes, Series editor, and Baumgartner, Matthias, editor

Published
2017
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20. Dietary Considerations in Tyrosinemia Type I

Author

van Spronsen, Francjan J., van Rijn, Margreet, Meyer, Uta, Das, Anibh M., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, and Tanguay, Robert M., editor

Published
2017
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22. Liver Cancer in Tyrosinemia Type 1

Author

van Ginkel, Willem G., Pennings, Jan P., van Spronsen, Francjan J., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, and Tanguay, Robert M., editor

Published
2017
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23. Phenylalanine effects on brain function in adult phenylketonuria

Author

Pilotto, Andrea, Zipser, Carl M., Leks, Edytha, Haas, Dorothea, Gramer, Gwendolyn, Freisinger, Peter, Schaeffer, Eva, Liepelt-Scarfone, Inga, Brockmann, Kathrin, Maetzler, Walter, Schulte, Claudia, Deuschle, Christian, Hauser, Ann Kathrin, Hoffmann, Georg F., Scheffler, Klaus, van Spronsen, Francjan J., Padovani, Alessandro, Trefz, Friedrich, and Berg, Daniela

Published
2020
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25. Newborn screening for primary carnitine deficiency: who will benefit? – a retrospective cohort study

Author

Crefcoeur, Loek, primary, Ferdinandusse, Sacha, additional, van der Crabben, Saskia N, additional, Dekkers, Eugènie, additional, Fuchs, Sabine A, additional, Huidekoper, Hidde, additional, Janssen, Mirian, additional, Langendonk, Janneke, additional, Maase, Rose, additional, de Sain, Monique, additional, Rubio, Estela, additional, van Spronsen, Francjan J, additional, Vaz, Frédéric Maxime, additional, Verschoof, Rendelien, additional, de Vries, Maaike, additional, Wijburg, Frits, additional, Visser, Gepke, additional, and Langeveld, Mirjam, additional

Published
2023
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28. Voluntary Exercise Prevents Oxidative Stress in the Brain of Phenylketonuria Mice

Author

Mazzola, Priscila Nicolao, Bruinenberg, Vibeke, Anjema, Karen, van Vliet, Danique, Dutra-Filho, Carlos Severo, van Spronsen, Francjan J., van der Zee, Eddy A., Baumgartner, Matthias, Series editor, Patterson, Marc, Series editor, Rahman, Shamima, Series editor, Peters, Verena, Series editor, Morava, Eva, Editor-in-chief, and Zschocke, Johannes, Series editor

Published
2016
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29. Key European guidelines for the diagnosis and management of patients with phenylketonuria

Author

van Spronsen, Francjan J, van Wegberg, Annemiek MJ, Ahring, Kirsten, Bélanger-Quintana, Amaya, Blau, Nenad, Bosch, Annet M, Burlina, Alberto, Campistol, Jaime, Feillet, Francois, Giżewska, Maria, Huijbregts, Stephan C, Kearney, Shauna, Leuzzi, Vincenzo, Maillot, Francois, Muntau, Ania C, Trefz, Fritz K, van Rijn, Margreet, Walter, John H, and MacDonald, Anita

Published
2017
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31. Emotional and behavioral problems, quality of life and metabolic control in NTBC-treated Tyrosinemia type 1 patients

Author

van Vliet, Kimber, van Ginkel, Willem G., Jahja, Rianne, Daly, Anne, MacDonald, Anita, De Laet, Corinne, Vara, Roshni, Rahman, Yusof, Cassiman, David, Eyskens, Francois, Timmer, Corrie, Mumford, Nicky, Bierau, Jörgen, van Hasselt, Peter M., Gissen, Paul, Goyens, Philippe J., McKiernan, Patrick J., Wilcox, Gisela, Morris, Andrew A. M., Jameson, Elisabeth A., Huijbregts, Stephan C. J., and van Spronsen, Francjan J.

Published
2019
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32. Infants with Tyrosinemia Type 1: Should phenylalanine be supplemented?

Author

van Vliet, Danique, van Dam, Esther, van Rijn, Margreet, Derks, Terry G. J., Venema-Liefaard, Gineke, Hitzert, Marrit M., Lunsing, Roelineke J., Heiner-Fokkema, M. Rebecca, van Spronsen, Francjan J., Zschocke, Johannes, Editor-in-chief, Baumgartner, Matthias, Series editor, Gibson, K Michael, Editor-in-chief, Patterson, Marc, Series editor, Rahman, Shamima, Series editor, Morava, Eva, editor, and Peters, Verena, editor

Published
2015
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34. A Delphi Survey Study to Formulate Statements on the Treatability of Inherited Metabolic Disorders to Decide on Eligibility for Newborn Screening

Author

Veldman, Abigail, Kiewiet, M. B.Gea, Westra, Dineke, Bosch, Annet M., Brands, Marion M.G., de Coo, René I.F.M., Derks, Terry G.J., Fuchs, Sabine A., van den Hout, Johanna M.P., Huidekoper, Hidde H., Kluijtmans, Leo A.J., Koop, Klaas, Lubout, Charlotte M.A., Mulder, Margaretha F., Panis, Bianca, Rubio-Gozalbo, M. Estela, de Sain-van der Velden, Monique G., Schaefers, Jaqueline, Schreuder, Andrea B., Visser, Gepke, Wevers, Ron A., Wijburg, Frits A., Heiner-Fokkema, M. Rebecca, van Spronsen, Francjan J., Veldman, Abigail, Kiewiet, M. B.Gea, Westra, Dineke, Bosch, Annet M., Brands, Marion M.G., de Coo, René I.F.M., Derks, Terry G.J., Fuchs, Sabine A., van den Hout, Johanna M.P., Huidekoper, Hidde H., Kluijtmans, Leo A.J., Koop, Klaas, Lubout, Charlotte M.A., Mulder, Margaretha F., Panis, Bianca, Rubio-Gozalbo, M. Estela, de Sain-van der Velden, Monique G., Schaefers, Jaqueline, Schreuder, Andrea B., Visser, Gepke, Wevers, Ron A., Wijburg, Frits A., Heiner-Fokkema, M. Rebecca, and van Spronsen, Francjan J.

Abstract

The Wilson and Jungner (W&J) and Andermann criteria are meant to help select diseases eligible for population-based screening. With the introduction of next-generation sequencing (NGS) methods for newborn screening (NBS), more inherited metabolic diseases (IMDs) can technically be included, and a revision of the criteria was attempted. This study aimed to formulate statements and investigate whether those statements could elaborate on the criterion of treatability for IMDs to decide on eligibility for NBS. An online Delphi study was started among a panel of Dutch IMD experts (EPs). EPs evaluated, amended, and approved statements on treatability that were subsequently applied to 10 IMDs. After two rounds of Delphi, consensus was reached on 10 statements. Application of these statements selected 5 out of 10 IMDs proposed for this study as eligible for NBS, including 3 IMDs in the current Dutch NBS. The statement: ‘The expected benefit/burden ratio of early treatment is positive and results in a significant health outcome’ contributed most to decision-making. Our Delphi study resulted in 10 statements that can help to decide on eligibility for inclusion in NBS based on treatability, also showing that other criteria could be handled in a comparable way. Validation of the statements is required before these can be applied as guidance to authorities.

Published
2023

35. Newborn screening for primary carnitine deficiency:Who will benefit? - A retrospective cohort study

Author

Crefcoeur, Loek, Ferdinandusse, Sacha, Van Der Crabben, Saskia N., Dekkers, Eugènie, Fuchs, Sabine A., Huidekoper, Hidde, Janssen, Mirian, Langendonk, Janneke, Maase, Rose, De Sain, Monique, Rubio, Estela, Van Spronsen, Francjan J., Vaz, Frédéric Maxime, Verschoof, Rendelien, De Vries, Maaike, Wijburg, Frits, Visser, Gepke, Langeveld, Mirjam, Crefcoeur, Loek, Ferdinandusse, Sacha, Van Der Crabben, Saskia N., Dekkers, Eugènie, Fuchs, Sabine A., Huidekoper, Hidde, Janssen, Mirian, Langendonk, Janneke, Maase, Rose, De Sain, Monique, Rubio, Estela, Van Spronsen, Francjan J., Vaz, Frédéric Maxime, Verschoof, Rendelien, De Vries, Maaike, Wijburg, Frits, Visser, Gepke, and Langeveld, Mirjam

Abstract

Background Newborn screening (NBS) programmes identify a wide range of disease phenotypes, which raises the question whether early identification and treatment is beneficial for all. This study aims to answer this question for primary carnitine deficiency (PCD) taking into account that NBS for PCD identifies newborns with PCD and also until then undiagnosed mothers. Methods We investigated clinical, genetic (variants in SLC22A5 gene) and functional (carnitine transport activity in fibroblasts) characteristics of all referred individuals through NBS (newborns and mothers) and clinically diagnosed patients with PCD (not through NBS). Disease phenotype in newborns was predicted using data from PCD mothers and cases published in literature with identical SLC22A5 variants. Results PCD was confirmed in 19/131 referred newborns, 37/82 referred mothers and 5 clinically diagnosed patients. Severe symptoms were observed in all clinically diagnosed patients, 1 newborn and none of the mothers identified by NBS. PCD was classified as severe in all 5 clinically diagnosed patients, 3/19 newborns and 1/37 mothers; as benign in 8/19 newborns and 36/37 mothers and as unknown in 8/19 newborns. Carnitine transport activity completely separated severe phenotype from benign phenotype (median (range): 4.0% (3.5-5.0)] vs 26% (9.5-42.5), respectively). Conclusion The majority of mothers and a significant proportion of newborns with PCD identified through NBS are likely to remain asymptomatic without early treatment. Conversely, a small proportion of newborns with predicted severe PCD could greatly benefit from early treatment. Genetic variants and carnitine transport activity can be used to distinguish between these groups. & amp; copy; & amp; copy; Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

Published
2023

36. A Delphi Survey Study to Formulate Statements on the Treatability of Inherited Metabolic Disorders to Decide on Eligibility for Newborn Screening

Author

Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, Genetica Sectie Metabole Diagnostiek, Veldman, Abigail, Kiewiet, M B Gea, Westra, Dineke, Bosch, Annet M, Brands, Marion M G, de Coo, René I F M, Derks, Terry G J, Fuchs, Sabine A, van den Hout, Johanna M P, Huidekoper, Hidde H, Kluijtmans, Leo A J, Koop, Klaas, Lubout, Charlotte M A, Mulder, Margaretha F, Panis, Bianca, Rubio-Gozalbo, M Estela, de Sain-van der Velden, Monique G, Schaefers, Jaqueline, Schreuder, Andrea B, Visser, Gepke, Wevers, Ron A, Wijburg, Frits A, Heiner-Fokkema, M Rebecca, van Spronsen, Francjan J, Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, Genetica Sectie Metabole Diagnostiek, Veldman, Abigail, Kiewiet, M B Gea, Westra, Dineke, Bosch, Annet M, Brands, Marion M G, de Coo, René I F M, Derks, Terry G J, Fuchs, Sabine A, van den Hout, Johanna M P, Huidekoper, Hidde H, Kluijtmans, Leo A J, Koop, Klaas, Lubout, Charlotte M A, Mulder, Margaretha F, Panis, Bianca, Rubio-Gozalbo, M Estela, de Sain-van der Velden, Monique G, Schaefers, Jaqueline, Schreuder, Andrea B, Visser, Gepke, Wevers, Ron A, Wijburg, Frits A, Heiner-Fokkema, M Rebecca, and van Spronsen, Francjan J

Published
2023

37. Newborn screening for primary carnitine deficiency: who will benefit? - a retrospective cohort study

Author

Cancer, Metabole ziekten onderzoek 1, Genetica, Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, Genetica Sectie Metabole Diagnostiek, MDL onderzoek 1, Infection & Immunity, Crefcoeur, Loek, Ferdinandusse, Sacha, van der Crabben, Saskia N, Dekkers, Eugènie, Fuchs, Sabine A, Huidekoper, Hidde, Janssen, Mirian, Langendonk, Janneke, Maase, Rose, de Sain, Monique, Rubio, Estela, van Spronsen, Francjan J, Vaz, Frédéric Maxime, Verschoof, Rendelien, de Vries, Maaike, Wijburg, Frits, Visser, Gepke, Langeveld, Mirjam, Cancer, Metabole ziekten onderzoek 1, Genetica, Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, Genetica Sectie Metabole Diagnostiek, MDL onderzoek 1, Infection & Immunity, Crefcoeur, Loek, Ferdinandusse, Sacha, van der Crabben, Saskia N, Dekkers, Eugènie, Fuchs, Sabine A, Huidekoper, Hidde, Janssen, Mirian, Langendonk, Janneke, Maase, Rose, de Sain, Monique, Rubio, Estela, van Spronsen, Francjan J, Vaz, Frédéric Maxime, Verschoof, Rendelien, de Vries, Maaike, Wijburg, Frits, Visser, Gepke, and Langeveld, Mirjam

Published
2023

39. Efficacy and safety of cyclic pyranopterin monophosphate substitution in severe molybdenum cofactor deficiency type A: a prospective cohort study

Author

Schwahn, Bernd C, Van Spronsen, Francjan J, Belaidi, Abdel A, Bowhay, Stephen, Christodoulou, John, Derks, Terry G, Hennermann, Julia B, Jameson, Elisabeth, König, Kai, McGregor, Tracy L, Font-Montgomery, Esperanza, Santamaria-Araujo, José A, Santra, Saikat, Vaidya, Mamta, Vierzig, Anne, Wassmer, Evangeline, Weis, Ilona, Wong, Flora Y, Veldman, Alex, and Schwarz, Günter

Published
2015
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44. Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder

Author

Friederich, Marisa W., Timal, Sharita, Powell, Christopher A., Dallabona, Cristina, Kurolap, Alina, Palacios-Zambrano, Sara, Bratkovic, Drago, Derks, Terry G. J., Bick, David, Bouman, Katelijne, Chatfield, Kathryn C., Damouny-Naoum, Nadine, Dishop, Megan K., Falik-Zaccai, Tzipora C., Fares, Fuad, Fedida, Ayalla, Ferrero, Ileana, Gallagher, Renata C., Garesse, Rafael, Gilberti, Micol, González, Cristina, Gowan, Katherine, Habib, Clair, Halligan, Rebecca K., Kalfon, Limor, Knight, Kaz, Lefeber, Dirk, Mamblona, Laura, Mandel, Hanna, Mory, Adi, Ottoson, John, Paperna, Tamar, Pruijn, Ger J. M., Rebelo-Guiomar, Pedro F., Saada, Ann, Sainz, Jr., Bruno, Salvemini, Hayley, Schoots, Mirthe H., Smeitink, Jan A., Szukszto, Maciej J., ter Horst, Hendrik J., van den Brandt, Frans, van Spronsen, Francjan J., Veltman, Joris A., Wartchow, Eric, Wintjes, Liesbeth T., Zohar, Yaniv, Fernández-Moreno, Miguel A., Baris, Hagit N., Donnini, Claudia, Minczuk, Michal, Rodenburg, Richard J., and Van Hove, Johan L. K.

Published
2018
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45. Can untreated PKU patients escape from intellectual disability? A systematic review

Author

van Vliet, Danique, van Wegberg, Annemiek M. J., Ahring, Kirsten, Bik-Multanowski, Miroslaw, Blau, Nenad, Bulut, Fatma D., Casas, Kari, Didycz, Bozena, Djordjevic, Maja, Federico, Antonio, Feillet, François, Gizewska, Maria, Gramer, Gwendolyn, Hertecant, Jozef L., Hollak, Carla E. M., Jørgensen, Jens V., Karall, Daniela, Landau, Yuval, Leuzzi, Vincenzo, Mathisen, Per, Moseley, Kathryn, Mungan, Neslihan Ö., Nardecchia, Francesca, Õunap, Katrin, Powell, Kimberly K., Ramachandran, Radha, Rutsch, Frank, Setoodeh, Aria, Stojiljkovic, Maja, Trefz, Fritz K., Usurelu, Natalia, Wilson, Callum, van Karnebeek, Clara D., Hanley, William B., and van Spronsen, Francjan J.

Published
2018
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49. Neurocognitive outcome and mental health in children with tyrosinemia type 1 and phenylketonuria: A comparison between two genetic disorders affecting the same metabolic pathway

Author

van Vliet, Kimber, primary, van Ginkel, Willem G., additional, Jahja, Rianne, additional, Daly, Anne, additional, MacDonald, Anita, additional, Santra, Saikat, additional, De Laet, Corinne, additional, Goyens, Philippe J., additional, Vara, Roshni, additional, Rahman, Yusof, additional, Cassiman, David, additional, Eyskens, Francois, additional, Timmer, Corrie, additional, Mumford, Nicky, additional, Gissen, Paul, additional, Bierau, Jörgen, additional, van Hasselt, Peter M., additional, Wilcox, Gisela, additional, Morris, Andrew A. M., additional, Jameson, Elisabeth A., additional, de la Parra, Alicia, additional, Arias, Carolina, additional, Garcia, Maria I., additional, Cornejo, Veronica, additional, Bosch, Annet M., additional, Hollak, Carla E. M., additional, Rubio‐Gozalbo, M. Estela, additional, Brouwers, Martijn C. G. J., additional, Hofstede, Floris C., additional, de Vries, Maaike C., additional, Janssen, Mirian C. H., additional, van der Ploeg, Ans T., additional, Langendonk, Janneke G., additional, Huijbregts, Stephan C. J., additional, and van Spronsen, Francjan J., additional

Published
2022
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50. Caring for Ukrainian refugee children with acute and chronic diseases

Author

Giżewska, Maria, van Wegberg, Annemiek M.J., Maillot, François, Trefz, Friedrich, van Spronsen, Francjan J., and Center for Liver, Digestive and Metabolic Diseases (CLDM)

Subjects
Refugees, Chronic Disease, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Ethnicity, Humans, General Medicine, Child
Abstract

Contains fulltext : 252139.pdf (Publisher’s version ) (Closed access)

Published
2022

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