357 results on '"van Erp, Theo G.M."'
Search Results
2. More reliable biomarkers and more accurate prediction for mental disorders using a label-noise filtering-based dimensional prediction method
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Xing, Ying, van Erp, Theo G.M., Pearlson, Godfrey D., Kochunov, Peter, Calhoun, Vince D., and Du, Yuhui
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- 2024
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3. Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study
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Bannai, Deepthi, Reuter, Martin, Hegde, Rachal, Hoang, Dung, Adhan, Iniya, Gandu, Swetha, Pong, Sovannarath, Raymond, Nick, Zeng, Victor, Chung, Yoonho, He, George, Sun, Daqiang, van Erp, Theo G.M., Addington, Jean, Bearden, Carrie E., Cadenhead, Kristin, Cornblatt, Barbara, Mathalon, Daniel H., McGlashan, Thomas, Jeffries, Clark, Stone, William, Tsuang, Ming, Walker, Elaine, Woods, Scott W., Cannon, Tyrone D., Perkins, Diana, Keshavan, Matcheri, and Lizano, Paulo
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- 2024
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4. Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium
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Zhu, Xi, Kim, Yoojean, Ravid, Orren, He, Xiaofu, Suarez-Jimenez, Benjamin, Zilcha-Mano, Sigal, Lazarov, Amit, Lee, Seonjoo, Abdallah, Chadi G., Angstadt, Michael, Averill, Christopher L., Baird, C. Lexi, Baugh, Lee A., Blackford, Jennifer U., Bomyea, Jessica, Bruce, Steven E., Bryant, Richard A., Cao, Zhihong, Choi, Kyle, Cisler, Josh, Cotton, Andrew S., Daniels, Judith K., Davenport, Nicholas D., Davidson, Richard J., DeBellis, Michael D., Dennis, Emily L., Densmore, Maria, deRoon-Cassini, Terri, Disner, Seth G., Hage, Wissam El, Etkin, Amit, Fani, Negar, Fercho, Kelene A., Fitzgerald, Jacklynn, Forster, Gina L., Frijling, Jessie L., Geuze, Elbert, Gonenc, Atilla, Gordon, Evan M., Gruber, Staci, Grupe, Daniel W, Guenette, Jeffrey P., Haswell, Courtney C., Herringa, Ryan J., Herzog, Julia, Hofmann, David Bernd, Hosseini, Bobak, Hudson, Anna R., Huggins, Ashley A., Ipser, Jonathan C., Jahanshad, Neda, Jia-Richards, Meilin, Jovanovic, Tanja, Kaufman, Milissa L., Kennis, Mitzy, King, Anthony, Kinzel, Philipp, Koch, Saskia B.J., Koerte, Inga K., Koopowitz, Sheri M., Korgaonkar, Mayuresh S., Krystal, John H., Lanius, Ruth, Larson, Christine L., Lebois, Lauren A.M., Li, Gen, Liberzon, Israel, Lu, Guang Ming, Luo, Yifeng, Magnotta, Vincent A., Manthey, Antje, Maron-Katz, Adi, May, Geoffery, McLaughlin, Katie, Mueller, Sven C., Nawijn, Laura, Nelson, Steven M., Neufeld, Richard W.J., Nitschke, Jack B, O'Leary, Erin M., Olatunji, Bunmi O., Olff, Miranda, Peverill, Matthew, Phan, K. Luan, Qi, Rongfeng, Quidé, Yann, Rektor, Ivan, Ressler, Kerry, Riha, Pavel, Ross, Marisa, Rosso, Isabelle M., Salminen, Lauren E., Sambrook, Kelly, Schmahl, Christian, Shenton, Martha E., Sheridan, Margaret, Shih, Chiahao, Sicorello, Maurizio, Sierk, Anika, Simmons, Alan N., Simons, Raluca M., Simons, Jeffrey S., Sponheim, Scott R., Stein, Murray B., Stein, Dan J., Stevens, Jennifer S., Straube, Thomas, Sun, Delin, Théberge, Jean, Thompson, Paul M., Thomopoulos, Sophia I., van der Wee, Nic J.A., van der Werff, Steven J.A., van Erp, Theo G.M., van Rooij, Sanne J.H., van Zuiden, Mirjam, Varkevisser, Tim, Veltman, Dick J., Vermeiren, Robert R.J.M., Walter, Henrik, Wang, Li, Wang, Xin, Weis, Carissa, Winternitz, Sherry, Xie, Hong, Zhu, Ye, Wall, Melanie, Neria, Yuval, and Morey, Rajendra A.
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- 2023
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5. Auditory oddball hypoactivation in schizophrenia
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Nakahara, Soichiro, Male, Alie G., Turner, Jessica A., Calhoun, Vince D., Lim, Kelvin O., Mueller, Bryon A., Bustillo, Juan R., O'Leary, Daniel S., Voyvodic, James, Belger, Aysenil, Preda, Adrian, Mathalon, Daniel H., Ford, Judith M., Guffanti, Guia, Macciardi, Fabio, Potkin, Steven G., and Van Erp, Theo G.M.
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- 2023
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6. Multi-model order spatially constrained ICA reveals highly replicable group differences and consistent predictive results from resting data: A large N fMRI schizophrenia study
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Meng, Xing, Iraji, Armin, Fu, Zening, Kochunov, Peter, Belger, Aysenil, Ford, Judy M., McEwen, Sara, Mathalon, Daniel H., Mueller, Bryon A., Pearlson, Godfrey, Potkin, Steven G., Preda, Adrian, Turner, Jessica, van Erp, Theo G.M., Sui, Jing, and Calhoun, Vince D.
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- 2023
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7. Cerebral blood flow and cardiovascular risk effects on resting brain regional homogeneity
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Adhikari, Bhim M., Hong, L. Elliot, Zhao, Zhiwei, Wang, Danny J.J., Thompson, Paul M., Jahanshad, Neda, Zhu, Alyssa H., Holiga, Stefan, Turner, Jessica A., van Erp, Theo G.M., Calhoun, Vince D., Hatch, Kathryn S., Bruce, Heather, Hare, Stephanie M., Chiappelli, Joshua, Goldwaser, Eric L., Kvarta, Mark D., Ma, Yizhou, Du, Xiaoming, Nichols, Thomas E., Shuldiner, Alan R., Mitchell, Braxton D., Dukart, Juergen, Chen, Shuo, and Kochunov, Peter
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- 2022
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8. A comparison of methods to harmonize cortical thickness measurements across scanners and sites
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Sun, Delin, Rakesh, Gopalkumar, Haswell, Courtney C., Logue, Mark, Baird, C. Lexi, O'Leary, Erin N., Cotton, Andrew S., Xie, Hong, Tamburrino, Marijo, Chen, Tian, Dennis, Emily L., Jahanshad, Neda, Salminen, Lauren E., Thomopoulos, Sophia I., Rashid, Faisal, Ching, Christopher R.K., Koch, Saskia B.J., Frijling, Jessie L., Nawijn, Laura, van Zuiden, Mirjam, Zhu, Xi, Suarez-Jimenez, Benjamin, Sierk, Anika, Walter, Henrik, Manthey, Antje, Stevens, Jennifer S., Fani, Negar, van Rooij, Sanne J.H., Stein, Murray, Bomyea, Jessica, Koerte, Inga K., Choi, Kyle, van der Werff, Steven J.A., Vermeiren, Robert R.J.M., Herzog, Julia, Lebois, Lauren A.M., Baker, Justin T., Olson, Elizabeth A., Straube, Thomas, Korgaonkar, Mayuresh S., Andrew, Elpiniki, Zhu, Ye, Li, Gen, Ipser, Jonathan, Hudson, Anna R., Peverill, Matthew, Sambrook, Kelly, Gordon, Evan, Baugh, Lee, Forster, Gina, Simons, Raluca M., Simons, Jeffrey S., Magnotta, Vincent, Maron-Katz, Adi, du Plessis, Stefan, Disner, Seth G., Davenport, Nicholas, Grupe, Daniel W., Nitschke, Jack B., deRoon-Cassini, Terri A., Fitzgerald, Jacklynn M., Krystal, John H., Levy, Ifat, Olff, Miranda, Veltman, Dick J., Wang, Li, Neria, Yuval, De Bellis, Michael D., Jovanovic, Tanja, Daniels, Judith K., Shenton, Martha, van de Wee, Nic J.A., Schmahl, Christian, Kaufman, Milissa L., Rosso, Isabelle M., Sponheim, Scott R., Hofmann, David Bernd, Bryant, Richard A., Fercho, Kelene A., Stein, Dan J., Mueller, Sven C., Hosseini, Bobak, Phan, K. Luan, McLaughlin, Katie A., Davidson, Richard J., Larson, Christine L., May, Geoffrey, Nelson, Steven M., Abdallah, Chadi G., Gomaa, Hassaan, Etkin, Amit, Seedat, Soraya, Harpaz-Rotem, Ilan, Liberzon, Israel, van Erp, Theo G.M., Quidé, Yann, Wang, Xin, Thompson, Paul M., and Morey, Rajendra A.
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- 2022
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9. Virtual Ontogeny of Cortical Growth Preceding Mental Illness
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Patel, Yash, Shin, Jean, Abé, Christoph, Agartz, Ingrid, Alloza, Clara, Alnæs, Dag, Ambrogi, Sonia, Antonucci, Linda A., Arango, Celso, Arolt, Volker, Auzias, Guillaume, Ayesa-Arriola, Rosa, Banaj, Nerisa, Banaschewski, Tobias, Bandeira, Cibele, Başgöze, Zeynep, Cupertino, Renata Basso, Bau, Claiton H.D., Bauer, Jochen, Baumeister, Sarah, Bernardoni, Fabio, Bertolino, Alessandro, Bonnin, Caterina del Mar, Brandeis, Daniel, Brem, Silvia, Bruggemann, Jason, Bülow, Robin, Bustillo, Juan R., Calderoni, Sara, Calvo, Rosa, Canales-Rodríguez, Erick J., Cannon, Dara M., Carmona, Susanna, Carr, Vaughan J., Catts, Stanley V., Chenji, Sneha, Chew, Qian Hui, Coghill, David, Connolly, Colm G., Conzelmann, Annette, Craven, Alexander R., Crespo-Facorro, Benedicto, Cullen, Kathryn, Dahl, Andreas, Dannlowski, Udo, Davey, Christopher G., Deruelle, Christine, Díaz-Caneja, Covadonga M., Dohm, Katharina, Ehrlich, Stefan, Epstein, Jeffery, Erwin-Grabner, Tracy, Eyler, Lisa T., Fedor, Jennifer, Fitzgerald, Jacqueline, Foran, William, Ford, Judith M., Fortea, Lydia, Fuentes-Claramonte, Paola, Fullerton, Janice, Furlong, Lisa, Gallagher, Louise, Gao, Bingchen, Gao, Si, Goikolea, Jose M., Gotlib, Ian, Goya-Maldonado, Roberto, Grabe, Hans J., Green, Melissa, Grevet, Eugenio H., Groenewold, Nynke A., Grotegerd, Dominik, Gruber, Oliver, Haavik, Jan, Hahn, Tim, Harrison, Ben J., Heindel, Walter, Henskens, Frans, Heslenfeld, Dirk J., Hilland, Eva, Hoekstra, Pieter J., Hohmann, Sarah, Holz, Nathalie, Howells, Fleur M., Ipser, Jonathan C., Jahanshad, Neda, Jakobi, Babette, Jansen, Andreas, Janssen, Joost, Jonassen, Rune, Kaiser, Anna, Kaleda, Vasiliy, Karantonis, James, King, Joseph A., Kircher, Tilo, Kochunov, Peter, Koopowitz, Sheri-Michelle, Landén, Mikael, Landrø, Nils Inge, Lawrie, Stephen, Lebedeva, Irina, Luna, Beatriz, Lundervold, Astri J., MacMaster, Frank P., Maglanoc, Luigi A., Mathalon, Daniel H., McDonald, Colm, McIntosh, Andrew, Meinert, Susanne, Michie, Patricia T., Mitchell, Philip, Moreno-Alcázar, Ana, Mowry, Bryan, Muratori, Filippo, Nabulsi, Leila, Nenadić, Igor, O'Gorman Tuura, Ruth, Oosterlaan, Jaap, Overs, Bronwyn, Pantelis, Christos, Parellada, Mara, Pariente, Jose C., Pauli, Paul, Pergola, Giulio, Piarulli, Francesco Maria, Picon, Felipe, Piras, Fabrizio, Pomarol-Clotet, Edith, Pretus, Clara, Quidé, Yann, Radua, Joaquim, Ramos-Quiroga, J. Antoni, Rasser, Paul E., Reif, Andreas, Retico, Alessandra, Roberts, Gloria, Rossell, Susan, Rovaris, Diego Luiz, Rubia, Katya, Sacchet, Matthew D., Salavert, Josep, Salvador, Raymond, Sarró, Salvador, Sawa, Akira, Schall, Ulrich, Scott, Rodney, Selvaggi, Pierluigi, Silk, Tim, Sim, Kang, Skoch, Antonin, Spalletta, Gianfranco, Spaniel, Filip, Stein, Dan J., Steinsträter, Olaf, Stolicyn, Aleks, Takayanagi, Yoichiro, Tamm, Leanne, Tavares, Maria, Teumer, Alexander, Thiel, Katharina, Thomopoulos, Sophia I., Tomecek, David, Tomyshev, Alexander S., Tordesillas-Gutiérrez, Diana, Tosetti, Michela, Uhlmann, Anne, Van Rheenen, Tamsyn, Vazquez-Bourgón, Javier, Vernooij, Meike W., Vieta, Eduard, Vilarroya, Oscar, Weickert, Cynthia, Weickert, Thomas, Westlye, Lars T., Whalley, Heather, Willinger, David, Winter, Alexandra, Wittfeld, Katharina, Yang, Tony T., Yoncheva, Yuliya, Zijlmans, Jendé L., Hoogman, Martine, Franke, Barbara, van Rooij, Daan, Buitelaar, Jan, Ching, Christopher R.K., Andreassen, Ole A., Pozzi, Elena, Veltman, Dick, Schmaal, Lianne, van Erp, Theo G.M., Turner, Jessica, Castellanos, F. Xavier, Pausova, Zdenka, Thompson, Paul, and Paus, Tomas
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- 2022
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10. Building Models of Functional Interactions Among Brain Domains that Encode Varying Information Complexity: A Schizophrenia Case Study
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Batta, Ishaan, Abrol, Anees, Fu, Zening, Preda, Adrian, van Erp, Theo G.M, and Calhoun, Vince D.
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- 2022
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11. 409. Cortico-Thalamic Structural Co-Variation Networks are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study
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Lella, Annalisa, primary, Antonucci, Linda A., additional, Weinberger, Daniel R., additional, Glahn, David C., additional, Sim, Kang, additional, Gruber, Oliver, additional, Chung, Young-Chul, additional, Sugranyes, Gisela, additional, Clote, Edith Pomarol, additional, Marcelis, Machteld, additional, Kircher, Tilo, additional, Van Rheenen, Tamsyn E., additional, Sponheim, Scott R., additional, Dannlowski, Udo, additional, Iasevoli, Felice, additional, Pearlson, Godfrey D., additional, Green, Melissa J., additional, Spalletta, Gianfranco, additional, Lee, Tae Young, additional, Turner, Jessica A., additional, van Erp, Theo G.M., additional, Thompson, Paul M., additional, Bertolino, Alessandro, additional, and Pergola, Giulio, additional
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- 2024
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12. Converting scores between the PANSS and SAPS/SANS beyond the positive/negative dichotomy
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Grot, Stéphanie, Giguère, Charles–Édouard, Smine, Salima, Mongeau-Pérusse, Violaine, Nguyen, Dana Diem, Preda, Adrian, Potvin, Stéphane, van Erp, Theo G.M., FBIRN, and Orban, Pierre
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- 2021
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13. Multiple overlapping dynamic patterns of the visual sensory network in schizophrenia
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Sendi, Mohammad S.E., Pearlson, Godfrey D., Mathalon, Daniel H., Ford, Judith M., Preda, Adrian, van Erp, Theo G.M., and Calhoun, Vince D.
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- 2021
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14. Progressive reconfiguration of resting-state brain networks as psychosis develops: Preliminary results from the North American Prodrome Longitudinal Study (NAPLS) consortium
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Cao, Hengyi, Chung, Yoonho, McEwen, Sarah C., Bearden, Carrie E., Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Carrión, Ricardo, Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Seidman, Larry J., Thermenos, Heidi, Tsuang, Ming T., van Erp, Theo G.M., Walker, Elaine F., Hamann, Stephan, Anticevic, Alan, Woods, Scott W., and Cannon, Tyrone D.
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- 2020
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15. Weighted average of shared trajectory: A new estimator for dynamic functional connectivity efficiently estimates both rapid and slow changes over time
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Faghiri, Ashkan, Iraji, Armin, Damaraju, Eswar, Belger, Aysenil, Ford, Judy, Mathalon, Daniel, Mcewen, Sarah, Mueller, Bryon, Pearlson, Godfrey, Preda, Adrian, Turner, Jessica, Vaidya, Jatin G., Van Erp, Theo G.M., and Calhoun, Vince D.
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- 2020
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16. Time-varying Spatial Propagation of Brain Networks in fMRI data
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Bostami, Biozid, primary, Lewis, Noah, additional, Agcaoglu, Oktay, additional, Turner, Jessica A., additional, van Erp, Theo G.M., additional, Ford, Judith M, additional, Calhoun, Vince, additional, and Iraji, Armin, additional
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- 2024
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17. Cross-paradigm connectivity: reliability, stability, and utility
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Cao, Hengyi, Chen, Oliver Y., McEwen, Sarah C., Forsyth, Jennifer K., Gee, Dylan G., Bearden, Carrie E., Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Carrión, Ricardo E., Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Thermenos, Heidi, Tsuang, Ming T., van Erp, Theo G.M., Walker, Elaine F., Hamann, Stephan, Anticevic, Alan, Woods, Scott W., and Cannon, Tyrone D.
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- 2021
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18. Genetic variants for head size share genes and pathways with cancer
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Knol, Maria J., Poot, Raymond A., Evans, Tavia E., Satizabal, Claudia L., Mishra, Aniket, Sargurupremraj, Muralidharan, van der Auwera, Sandra, Duperron, Marie Gabrielle, Jian, Xueqiu, Hostettler, Isabel C., van Dam-Nolen, Dianne H.K., Lamballais, Sander, Pawlak, Mikolaj A., Lewis, Cora E., Carrion-Castillo, Amaia, van Erp, Theo G.M., Reinbold, Céline S., Shin, Jean, Scholz, Markus, Håberg, Asta K., Kämpe, Anders, Li, Gloria H.Y., Avinun, Reut, Atkins, Joshua R., Hsu, Fang Chi, Amod, Alyssa R., Lam, Max, Bos, Daniel, Cecil, Charlotte A.M., Longstreth, W. T., Hilal, Saima, Niessen, Wiro J., Schmidt, Helena, Tiemeier, Henning, Bernard, Manon, Blanken, Laura M.E., Hottenga, Jouke Jan, Ophoff, Roel A., Pappa, Irene, Shen, Li, Van Haren, Neeltje E.M., Muetzel, Ryan, Roshchupkin, Gennady V., Teumer, Alexander, van der Lugt, Aad, Vernooij, Meike W., White, Tonya, Koudstaal, Peter J., Ikram, M. Arfan, Adams, Hieab H.H., Knol, Maria J., Poot, Raymond A., Evans, Tavia E., Satizabal, Claudia L., Mishra, Aniket, Sargurupremraj, Muralidharan, van der Auwera, Sandra, Duperron, Marie Gabrielle, Jian, Xueqiu, Hostettler, Isabel C., van Dam-Nolen, Dianne H.K., Lamballais, Sander, Pawlak, Mikolaj A., Lewis, Cora E., Carrion-Castillo, Amaia, van Erp, Theo G.M., Reinbold, Céline S., Shin, Jean, Scholz, Markus, Håberg, Asta K., Kämpe, Anders, Li, Gloria H.Y., Avinun, Reut, Atkins, Joshua R., Hsu, Fang Chi, Amod, Alyssa R., Lam, Max, Bos, Daniel, Cecil, Charlotte A.M., Longstreth, W. T., Hilal, Saima, Niessen, Wiro J., Schmidt, Helena, Tiemeier, Henning, Bernard, Manon, Blanken, Laura M.E., Hottenga, Jouke Jan, Ophoff, Roel A., Pappa, Irene, Shen, Li, Van Haren, Neeltje E.M., Muetzel, Ryan, Roshchupkin, Gennady V., Teumer, Alexander, van der Lugt, Aad, Vernooij, Meike W., White, Tonya, Koudstaal, Peter J., Ikram, M. Arfan, and Adams, Hieab H.H.
- Abstract
The size of the human head is highly heritable, but genetic drivers of its variation within the general population remain unmapped. We perform a genome-wide association study on head size (N = 80,890) and identify 67 genetic loci, of which 50 are novel. Neuroimaging studies show that 17 variants affect specific brain areas, but most have widespread effects. Gene set enrichment is observed for various cancers and the p53, Wnt, and ErbB signaling pathways. Genes harboring lead variants are enriched for macrocephaly syndrome genes (37-fold) and high-fidelity cancer genes (9-fold), which is not seen for human height variants. Head size variants are also near genes preferentially expressed in intermediate progenitor cells, neural cells linked to evolutionary brain expansion. Our results indicate that genes regulating early brain and cranial growth incline to neoplasia later in life, irrespective of height. This warrants investigation of clinical implications of the link between head size and cancer.
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- 2024
19. Normative Modeling of Brain Morphometry in Clinical High Risk for Psychosis
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Haas, Shalaila S., Ge, Ruiyang, Agartz, Ingrid, Amminger, G. Paul, Andreassen, Ole A., Bachman, Peter, Baeza, Inmaculada, Choi, Sunah, Colibazzi, Tiziano, Cropley, Vanessa L., De La Fuente-Sandoval, Camilo, Ebdrup, Bjørn H., Fortea, Adriana, Fusar-Poli, Paolo, Glenthøj, Birte Yding, Glenthøj, Louise Birkedal, Haut, Kristen M., Hayes, Rebecca A., Heekeren, Karsten, Hooker, Christine I., Hwang, Wu Jeong, Jahanshad, Neda, Kaess, Michael, Kasai, Kiyoto, Katagiri, Naoyuki, Kim, Minah, Kindler, Jochen, Koike, Shinsuke, Kristensen, Tina D., Kwon, Jun Soo, Lawrie, Stephen M., Lebedeva, Irina, Lee, Jimmy, Lemmers-Jansen, Imke L.J., Lin, Ashleigh, Ma, Xiaoqian, Mathalon, Daniel H., McGuire, Philip, Michel, Chantal, Mizrahi, Romina, Mizuno, Masafumi, Møller, Paul, Mora-Durán, Ricardo, Nelson, Barnaby, Nemoto, Takahiro, Nordentoft, Merete, Nordholm, Dorte, Omelchenko, Maria A., Pantelis, Christos, Pariente, Jose C., Raghava, Jayachandra M., Reyes-Madrigal, Francisco, Røssberg, Jan I., Rössler, Wulf, Salisbury, Dean F., Sasabayashi, Daiki, Schall, Ulrich, Smigielski, Lukasz, Sugranyes, Gisela, Suzuki, Michio, Takahashi, Tsutomu, Tamnes, Christian K., Theodoridou, Anastasia, Thomopoulos, Sophia I., Thompson, Paul M., Tomyshev, Alexander S., Uhlhaas, Peter J., Værnes, Tor G., Van Amelsvoort, Therese A.M.J., Van Erp, Theo G.M., Waltz, James A., Wenneberg, Christina, Westlye, Lars T., Wood, Stephen J., Zhou, Juan H., Hernaus, Dennis, Jalbrzikowski, Maria, Kahn, René S., Corcoran, Cheryl M., Frangou, Sophia, Haas, Shalaila S., Ge, Ruiyang, Agartz, Ingrid, Amminger, G. Paul, Andreassen, Ole A., Bachman, Peter, Baeza, Inmaculada, Choi, Sunah, Colibazzi, Tiziano, Cropley, Vanessa L., De La Fuente-Sandoval, Camilo, Ebdrup, Bjørn H., Fortea, Adriana, Fusar-Poli, Paolo, Glenthøj, Birte Yding, Glenthøj, Louise Birkedal, Haut, Kristen M., Hayes, Rebecca A., Heekeren, Karsten, Hooker, Christine I., Hwang, Wu Jeong, Jahanshad, Neda, Kaess, Michael, Kasai, Kiyoto, Katagiri, Naoyuki, Kim, Minah, Kindler, Jochen, Koike, Shinsuke, Kristensen, Tina D., Kwon, Jun Soo, Lawrie, Stephen M., Lebedeva, Irina, Lee, Jimmy, Lemmers-Jansen, Imke L.J., Lin, Ashleigh, Ma, Xiaoqian, Mathalon, Daniel H., McGuire, Philip, Michel, Chantal, Mizrahi, Romina, Mizuno, Masafumi, Møller, Paul, Mora-Durán, Ricardo, Nelson, Barnaby, Nemoto, Takahiro, Nordentoft, Merete, Nordholm, Dorte, Omelchenko, Maria A., Pantelis, Christos, Pariente, Jose C., Raghava, Jayachandra M., Reyes-Madrigal, Francisco, Røssberg, Jan I., Rössler, Wulf, Salisbury, Dean F., Sasabayashi, Daiki, Schall, Ulrich, Smigielski, Lukasz, Sugranyes, Gisela, Suzuki, Michio, Takahashi, Tsutomu, Tamnes, Christian K., Theodoridou, Anastasia, Thomopoulos, Sophia I., Thompson, Paul M., Tomyshev, Alexander S., Uhlhaas, Peter J., Værnes, Tor G., Van Amelsvoort, Therese A.M.J., Van Erp, Theo G.M., Waltz, James A., Wenneberg, Christina, Westlye, Lars T., Wood, Stephen J., Zhou, Juan H., Hernaus, Dennis, Jalbrzikowski, Maria, Kahn, René S., Corcoran, Cheryl M., and Frangou, Sophia
- Abstract
Question Are brain morphometric changes that deviate significantly from healthy variation associated with the risk of psychosis? Findings In this case-control study of 1340 individuals at clinical high risk for psychosis and 1237 healthy participants, individual-level variation in macroscale neuromorphometric measures in the group at clinical high risk for psychosis was largely nested within healthy variation and was not associated with the severity of positive symptoms or conversion to a psychotic disorder. Meaning The findings suggest the macroscale neuromorphometric measures have limited utility as diagnostic biomarkers of psychosis risk. Abstract Importance The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in individuals at psychosis risk may be nested within the range observed in healthy individuals. Objective To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with positive symptoms, cognition, and conversion to a psychotic disorder. Design, Setting, and Participants This case-control study used clinical-, IQ-, and neuroimaging software (FreeSurfer)–derived regional measures of cortical thickness (CT), cortical surface area (SA), and subcortical volume (SV) from 1340 individuals with CHR-P and 1237 healthy individuals pooled from 29 international sites participating in the Enhancing Neuroimaging Genetics Through Meta-analysis (ENIGMA) Clinical High Risk for Psychosis Working Group. Healthy individuals and individuals with CHR-P were matched on age and sex within each recruitment site. Data were analyzed between September 1, 2021, and November 30, 2022. Main Outcomes and Measures For each regional morphometric measure, Importance: The lack of robust neuroanatomical markers of psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in neuroanatomical measures in individuals at psychosis risk may be nested within the range observed in healthy individuals. Objective: To quantify deviations from the normative range of neuroanatomical variation in individuals at clinical high risk for psychosis (CHR-P) and evaluate their overlap with healthy variation and their association with positive symptoms, cognition, and conversion to a psychotic disorder. Design, Setting, and Participants: This case-control study used clinical-, IQ-, and neuroimaging software (FreeSurfer)-derived regional measures of cortical thickness (CT), cortical surface area (SA), and subcortical volume (SV) from 1340 individuals with CHR-P and 1237 healthy individuals pooled from 29 international sites participating in the Enhancing Neuroimaging Genetics Through Meta-analysis (ENIGMA) Clinical High Risk for Psychosis Working Group. Healthy individuals and individuals with CHR-P were matched on age and sex within each recruitment site. Data were analyzed between September 1, 2021, and November 30, 2022. Main Outcomes and Measures: For each regional morphometric measure, deviation scores were computed as z scores indexing the degree of deviation from their normative means from a healthy reference population. Average deviation scores (ADS) were also calculated for regional CT, SA, and SV measures and globally across all measures. Regression analyses quantified the association of deviation scores with clinical severity and cognition, and 2-proportion z tests identified case-control differences in the proportion of individuals with infranormal (z < -1.96) or supranormal (z > 1.96) scores. Results: Among 1340 individuals with CHR-P, 709 (52.91%) were male, and the mean (SD) age was 20.75 (4.74) years. Among 1237 healthy individuals, 684 (55.30%) were male, and the
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- 2024
20. The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder
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de Zwarte, Sonja M.C., Brouwer, Rachel M., Agartz, Ingrid, Alda, Martin, Aleman, André, Alpert, Kathryn I., Bearden, Carrie E., Bertolino, Alessandro, Bois, Catherine, Bonvino, Aurora, Bramon, Elvira, Buimer, Elizabeth E.L., Cahn, Wiepke, Cannon, Dara M., Cannon, Tyrone D., Caseras, Xavier, Castro-Fornieles, Josefina, Chen, Qiang, Chung, Yoonho, De la Serna, Elena, Di Giorgio, Annabella, Doucet, Gaelle E., Eker, Mehmet Cagdas, Erk, Susanne, Fears, Scott C., Foley, Sonya F., Frangou, Sophia, Frankland, Andrew, Fullerton, Janice M., Glahn, David C., Goghari, Vina M., Goldman, Aaron L., Gonul, Ali Saffet, Gruber, Oliver, de Haan, Lieuwe, Hajek, Tomas, Hawkins, Emma L., Heinz, Andreas, Hillegers, Manon H.J., Hulshoff Pol, Hilleke E., Hultman, Christina M., Ingvar, Martin, Johansson, Viktoria, Jönsson, Erik G., Kane, Fergus, Kempton, Matthew J., Koenis, Marinka M.G., Kopecek, Miloslav, Krabbendam, Lydia, Krämer, Bernd, Lawrie, Stephen M., Lenroot, Rhoshel K., Marcelis, Machteld, Marsman, Jan-Bernard C., Mattay, Venkata S., McDonald, Colm, Meyer-Lindenberg, Andreas, Michielse, Stijn, Mitchell, Philip B., Moreno, Dolores, Murray, Robin M., Mwangi, Benson, Najt, Pablo, Neilson, Emma, Newport, Jason, van Os, Jim, Overs, Bronwyn, Ozerdem, Aysegul, Picchioni, Marco M., Richter, Anja, Roberts, Gloria, Aydogan, Aybala Saricicek, Schofield, Peter R., Simsek, Fatma, Soares, Jair C., Sugranyes, Gisela, Toulopoulou, Timothea, Tronchin, Giulia, Walter, Henrik, Wang, Lei, Weinberger, Daniel R., Whalley, Heather C., Yalin, Nefize, Andreassen, Ole A., Ching, Christopher R.K., van Erp, Theo G.M., Turner, Jessica A., Jahanshad, Neda, Thompson, Paul M., Kahn, René S., and van Haren, Neeltje E.M.
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- 2019
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21. Positive and general psychopathology associated with specific gray matter reductions in inferior temporal regions in patients with schizophrenia
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Mennigen, Eva, Jiang, Wenhao, Calhoun, Vince D., van Erp, Theo G.M., Agartz, Ingrid, Ford, Judith M., Mueller, Bryon A., Liu, Jingyu, and Turner, Jessica A.
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- 2019
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22. A method for building a genome-connectome bipartite graph model
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Yu, Qingbao, Chen, Jiayu, Du, Yuhui, Sui, Jing, Damaraju, Eswar, Turner, Jessica A., van Erp, Theo G.M., Macciardi, Fabio, Belger, Aysenil, Ford, Judith M., McEwen, Sarah, Mathalon, Daniel H., Mueller, Bryon A., Preda, Adrian, Vaidya, Jatin, Pearlson, Godfrey D., and Calhoun, Vince D.
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- 2019
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23. Cortical abnormalities in youth at clinical high-risk for psychosis: Findings from the NAPLS2 cohort
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Chung, Yoonho, Allswede, Dana, Addington, Jean, Bearden, Carrie E., Cadenhead, Kristin, Cornblatt, Barbara, Mathalon, Daniel H., McGlashan, Thomas, Perkins, Diana, Seidman, Larry J., Tsuang, Ming, Walker, Elaine, Woods, Scott W., McEwen, Sarah, van Erp, Theo G.M., and Cannon, Tyrone D.
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- 2019
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24. A framework for linking resting-state chronnectome/genome features in schizophrenia: A pilot study
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Rashid, Barnaly, Chen, Jiayu, Rashid, Ishtiaque, Damaraju, Eswar, Liu, Jingyu, Miller, Robyn, Agcaoglu, Oktay, van Erp, Theo G.M., Lim, Kelvin O., Turner, Jessica A., Mathalon, Daniel H., Ford, Judith M., Voyvodic, James, Mueller, Bryon A., Belger, Aysenil, McEwen, Sarah, Potkin, Steven G., Preda, Adrian, Bustillo, Juan R., Pearlson, Godfrey D., and Calhoun, Vince D.
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- 2019
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25. Spatial Dynamic Subspaces Encode Sex-Specific Schizophrenia Disruptions in Transient Network Overlap and Their Links to Genetic Risk
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Iraji, Armin, primary, Chen, Jiayu, additional, Lewis, Noah, additional, Faghiri, Ashkan, additional, Fu, Zening, additional, Agcaoglu, Oktay, additional, Kochunov, Peter, additional, Adhikari, Bhim M., additional, Mathalon, Daniel H., additional, Pearlson, Godfrey D., additional, Macciardi, Fabio, additional, Preda, Adrian, additional, van Erp, Theo G.M., additional, Bustillo, Juan R., additional, Díaz-Caneja, Covadonga M., additional, Andrés-Camazón, Pablo, additional, Dhamala, Mukesh, additional, Adali, Tulay, additional, and Calhoun, Vince D., additional
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- 2023
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26. A positive take on schizophrenia negative symptom scales: Converting scores between the SANS, NSA and SDS
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Preda, Adrian, Nguyen, Dana D., Bustillo, Juan R., Belger, Aysenil, O'Leary, Daniel S., McEwen, Sarah, Ling, Shichun, Faziola, Lawrence, Mathalon, Daniel H., Ford, Judith M., Potkin, Steven G., and van Erp, Theo G.M.
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- 2018
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27. Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
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Farde, Lars, Flyckt, Lena, Engberg, Göran, Erhardt, Sophie, Fatouros-Bergman, Helena, Cervenka, Simon, Schwieler, Lilly, Piehl, Fredrik, Agartz, Ingrid, Collste, Karin, Victorsson, Pauliina, Malmqvist, Anna, Hedberg, Mikael, Orhan, Funda, van Erp, Theo G.M., Walton, Esther, Hibar, Derrek P., Schmaal, Lianne, Jiang, Wenhao, Glahn, David C., Pearlson, Godfrey D., Yao, Nailin, Fukunaga, Masaki, Hashimoto, Ryota, Okada, Naohiro, Yamamori, Hidenaga, Bustillo, Juan R., Clark, Vincent P., Mueller, Bryon A., Cahn, Wiepke, de Zwarte, Sonja M.C., Hulshoff Pol, Hilleke E., Kahn, René S., Ophoff, Roel A., van Haren, Neeltje E.M., Andreassen, Ole A., Dale, Anders M., Doan, Nhat Trung, Gurholt, Tiril P., Hartberg, Cecilie B., Haukvik, Unn K., Jørgensen, Kjetil N., Lagerberg, Trine V., Melle, Ingrid, Westlye, Lars T., Gruber, Oliver, Kraemer, Bernd, Richter, Anja, Zilles, David, Calhoun, Vince D., Crespo-Facorro, Benedicto, Roiz-Santiañez, Roberto, Tordesillas-Gutiérrez, Diana, Loughland, Carmel, Carr, Vaughan J., Catts, Stanley, Cropley, Vanessa L., Fullerton, Janice M., Green, Melissa J., Henskens, Frans A., Jablensky, Assen, Lenroot, Rhoshel K., Mowry, Bryan J., Michie, Patricia T., Pantelis, Christos, Quidé, Yann, Schall, Ulrich, Scott, Rodney J., Cairns, Murray J., Seal, Marc, Tooney, Paul A., Rasser, Paul E., Cooper, Gavin, Shannon Weickert, Cynthia, Weickert, Thomas W., Morris, Derek W., Hong, Elliot, Kochunov, Peter, Beard, Lauren M., Gur, Raquel E., Gur, Ruben C., Satterthwaite, Theodore D., Wolf, Daniel H., Belger, Aysenil, Brown, Gregory G., Ford, Judith M., Macciardi, Fabio, Mathalon, Daniel H., O’Leary, Daniel S., Potkin, Steven G., Preda, Adrian, Voyvodic, James, Lim, Kelvin O., McEwen, Sarah, Yang, Fude, Tan, Yunlong, Tan, Shuping, Wang, Zhiren, Fan, Fengmei, Chen, Jingxu, Xiang, Hong, Tang, Shiyou, Guo, Hua, Wan, Ping, Wei, Dong, Bockholt, Henry J., Ehrlich, Stefan, Wolthusen, Rick P.F., King, Margaret D., Shoemaker, Jody M., Sponheim, Scott R., De Haan, Lieuwe, Koenders, Laura, Machielsen, Marise W., van Amelsvoort, Therese, Veltman, Dick J., Assogna, Francesca, Banaj, Nerisa, de Rossi, Pietro, Iorio, Mariangela, Piras, Fabrizio, Spalletta, Gianfranco, McKenna, Peter J., Pomarol-Clotet, Edith, Salvador, Raymond, Corvin, Aiden, Donohoe, Gary, Kelly, Sinead, Whelan, Christopher D., Dickie, Erin W., Rotenberg, David, Voineskos, Aristotle N., Ciufolini, Simone, Radua, Joaquim, Dazzan, Paola, Murray, Robin, Reis Marques, Tiago, Simmons, Andrew, Borgwardt, Stefan, Egloff, Laura, Harrisberger, Fabienne, Riecher-Rössler, Anita, Smieskova, Renata, Alpert, Kathryn I., Wang, Lei, Jönsson, Erik G., Koops, Sanne, Sommer, Iris E.C., Bertolino, Alessandro, Bonvino, Aurora, Di Giorgio, Annabella, Neilson, Emma, Mayer, Andrew R., Stephen, Julia M., Kwon, Jun Soo, Yun, Je-Yeon, Cannon, Dara M., McDonald, Colm, Lebedeva, Irina, Tomyshev, Alexander S., Akhadov, Tolibjohn, Kaleda, Vasily, Busatto, Geraldo F., Rosa, Pedro G.P., Serpa, Mauricio H., Zanetti, Marcus V., Hoschl, Cyril, Skoch, Antonin, Spaniel, Filip, Tomecek, David, Hagenaars, Saskia P., McIntosh, Andrew M., Whalley, Heather C., Lawrie, Stephen M., Knöchel, Christian, Oertel-Knöchel, Viola, Stäblein, Michael, Howells, Fleur M., Stein, Dan J., Temmingh, Henk S., Uhlmann, Anne, Lopez-Jaramillo, Carlos, Dima, Danai, McMahon, Agnes, Faskowitz, Joshua I., Gutman, Boris A., Jahanshad, Neda, Thompson, Paul M., and Turner, Jessica A.
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- 2018
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28. Disrupted network cross talk, hippocampal dysfunction and hallucinations in schizophrenia
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Hare, Stephanie M., Law, Alicia S., Ford, Judith M., Mathalon, Daniel H., Ahmadi, Aral, Damaraju, Eswar, Bustillo, Juan, Belger, Aysenil, Lee, Hyo Jong, Mueller, Bryon A., Lim, Kelvin O., Brown, Gregory G., Preda, Adrian, van Erp, Theo G.M., Potkin, Steven G., Calhoun, Vince D., and Turner, Jessica A.
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- 2018
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29. Function Biomedical Informatics Research Network Recommendations for Prospective Multi-Center Functional Magnetic Resonance Imaging Studies
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Glover, Gary H., Mueller, Bryon A., Turner, Jessica A., van Erp, Theo G.M., Liu, Thomas T., Greve, Douglas N., Voyvodic, James T., Rasmussen, Jerod, Brown, Gregory G., Keator, David B., Calhoun, Vince D., Lee, Hyo Jong, Ford, Judith M., Mathalon, Daniel H., Diaz, Michele, O'Leary, Daniel S., Gadde, Syam, Preda, Adrian, Lim, Kelvin O., Wible, Cynthia G., Stern, Hal S., Belger, Aysenil, McCarthy, Gregory, Ozyurt, Burak, and Potkin, Steven G.
- Abstract
This report provides practical recommendations for the design and execution of Multi-Center functional Magnetic Resonance Imaging (MC-fMRI) studies based on the collective experience of the Function Biomedical Informatics Research Network (FBIRN). The paper was inspired by many requests from the fMRI community to FBIRN group members for advice on how to conduct MC-fMRI studies. The introduction briefly discusses the advantages and complexities of MC-fMRI studies. Prerequisites for MC-fMRI studies are addressed before delving into the practical aspects of carefully and efficiently setting up a MC-fMRI study. Practical multi-site aspects include: (1) establishing and verifying scan parameters including scanner types and magnetic fields, (2) establishing and monitoring of a scanner quality program, (3) developing task paradigms and scan session documentation, (4) establishing clinical and scanner training to ensure consistency over time, (5) developing means for uploading, storing, and monitoring of imaging and other data, (6) the use of a traveling fMRI expert and (7) collectively analyzing imaging data and disseminating results. We conclude that when MC-fMRI studies are organized well with careful attention to unification of hardware, software and procedural aspects, the process can be a highly effective means for accessing a desired participant demographics while accelerating scientific discovery.
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- 2012
30. Genetic variants for head size share genes and pathways with cancer
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Amouyel, Philippe, Arfanakis, Konstantinos, Aribisala, Benjamin S., Bastin, Mark E., Chauhan, Ganesh, Chen, Christopher, Cheng, Ching-Yu, de Jager, Philip L., Deary, Ian J., Fleischman, Debra A., Gottesman, Rebecca F., Gudnason, Vilmundur, Hilal, Saima, Hofer, Edith, Janowitz, Deborah, Jukema, J. Wouter, Liewald, David C.M., Lopez, Lorna M., Lopez, Oscar, Luciano, Michelle, Martinez, Oliver, Niessen, Wiro J., Nyquist, Paul, Rotter, Jerome I., Rundek, Tatjana, Sacco, Ralph L., Schmidt, Helena, Tiemeier, Henning, Trompet, Stella, van der Grond, Jeroen, Völzke, Henry, Wardlaw, Joanna M., Yanek, Lisa, Yang, Jingyun, Agartz, Ingrid, Alhusaini, Saud, Almasy, Laura, Ames, David, Amunts, Katrin, Andreassen, Ole A., Armstrong, Nicola, Bernard, Manon, Blangero, John, Blanken, Laura M.E., Boks, Marco P., Boomsma, Dorret I., Brickman, Adam M., Brodaty, Henry, Buckner, Randy L., Buitelaar, Jan K., Cannon, Dara M., Carr, Vaughan J., Catts, Stanley V., Chakravarty, M. Mallar, Chen, Qiang, Ching, Christopher R.K., Corvin, Aiden, Crespo-Facorro, Benedicto, Curran, Joanne E., Davies, Gareth E., de Geus, Eco J.C., de Zubicaray, Greig I., den Braber, Anouk, Desrivières, Sylvane, Dillman, Allissa, Djurovic, Srdjan, Drevets, Wayne C., Duggirala, Ravi, Ehrlich, Stefan, Erk, Susanne, Espeseth, Thomas, Fedko, Iryna O., Fernández, Guillén, Fisher, Simon E., Foroud, Tatiana M., Ge, Tian, Giddaluru, Sudheer, Glahn, David C., Goldman, Aaron L., Green, Robert C., Greven, Corina U., Grimm, Oliver, Hansell, Narelle K., Hartman, Catharina A., Hashimoto, Ryota, Heinz, Andreas, Henskens, Frans, Hibar, Derrek P., Ho, Beng-Choon, Hoekstra, Pieter J., Holmes, Avram J., Hoogman, Martine, Hottenga, Jouke-Jan, Hulshoff Pol, Hilleke E., Jablensky, Assen, Jenkinson, Mark, Jia, Tianye, Jöckel, Karl-Heinz, Jönsson, Erik G., Kim, Sungeun, Klein, Marieke, Kochunov, Peter, Kwok, John B., Lawrie, Stephen M., Le Hellard, Stephanie, Lemaître, Hervé, Loughland, Carmel, Marquand, Andre F., Martin, Nicholas G., Martinot, Jean-Luc, Matarin, Mar, Mathalon, Daniel H., Mather, Karen A., Mattay, Venkata S., McDonald, Colm, McMahon, Francis J., McMahon, Katie L., E, Rebekah, McWhirter, Mecocci, Patrizia, Melle, Ingrid, Meyer-Lindenberg, Andreas, Michie, Patricia T., Milaneschi, Yuri, Morris, Derek W., Mowry, Bryan, Nho, Kwangsik, Nichols, Thomas E., Nöthen, Markus N., Olvera, Rene L., Oosterlaan, Jaap, Ophoff, Roel A., Pandolfo, Massimo, Pantelis, Christos, Pappa, Irene, Penninx, Brenda, Pike, G. Bruce, Rasser, Paul E., Rentería, Miguel E., Reppermund, Simone, Rietschel, Marcella, Risacher, Shannon L., Romanczuk-Seiferth, Nina, Rose, Emma Jane, Sachdev, Perminder S., Sämann, Philipp G., Saykin, Andrew J., Schall, Ulrich, Schofield, Peter R., Schramm, Sara, Schumann, Gunter, Scott, Rodney, Shen, Li, Sisodiya, Sanjay M., Soininen, Hilkka, Sprooten, Emma, Srikanth, Velandai, Steen, Vidar M., Strike, Lachlan T., Thalamuthu, Anbupalam, Toga, Arthur W., Tooney, Paul, Tordesillas-Gutiérrez, Diana, Turner, Jessica A., Valdés Hernández, Maria del C., van der Meer, Dennis, Van der Wee, Nic J.A., Van Haren, Neeltje E.M., van 't Ent, Dennis, Veltman, Dick J., Walter, Henrik, Weinberger, Daniel R., Weiner, Michael W., Wen, Wei, Westlye, Lars T., Westman, Eric, Winkler, Anderson M., Woldehawariat, Girma, Wright, Margaret J., Wu, Jingqin, Knol, Maria J., Poot, Raymond A., Evans, Tavia E., Satizabal, Claudia L., Mishra, Aniket, Sargurupremraj, Muralidharan, van der Auwera, Sandra, Duperron, Marie-Gabrielle, Jian, Xueqiu, Hostettler, Isabel C., van Dam-Nolen, Dianne H.K., Lamballais, Sander, Pawlak, Mikolaj A., Lewis, Cora E., Carrion-Castillo, Amaia, van Erp, Theo G.M., Reinbold, Céline S., Shin, Jean, Scholz, Markus, Håberg, Asta K., Kämpe, Anders, Li, Gloria H.Y., Avinun, Reut, Atkins, Joshua R., Hsu, Fang-Chi, Amod, Alyssa R., Lam, Max, Tsuchida, Ami, Teunissen, Mariël W.A., Aygün, Nil, Patel, Yash, Liang, Dan, Beiser, Alexa S., Beyer, Frauke, Bis, Joshua C., Bos, Daniel, Bryan, R. Nick, Bülow, Robin, Caspers, Svenja, Catheline, Gwenaëlle, Cecil, Charlotte A.M., Dalvie, Shareefa, Dartigues, Jean-François, DeCarli, Charles, Enlund-Cerullo, Maria, Ford, Judith M., Franke, Barbara, Freedman, Barry I., Friedrich, Nele, Green, Melissa J., Haworth, Simon, Helmer, Catherine, Hoffmann, Per, Homuth, Georg, Ikram, M. Kamran, Jack, Clifford R., Jr., Jahanshad, Neda, Jockwitz, Christiane, Kamatani, Yoichiro, Knodt, Annchen R., Li, Shuo, Lim, Keane, Longstreth, W.T., Macciardi, Fabio, Mäkitie, Outi, Mazoyer, Bernard, Medland, Sarah E., Miyamoto, Susumu, Moebus, Susanne, Mosley, Thomas H., Muetzel, Ryan, Mühleisen, Thomas W., Nagata, Manabu, Nakahara, Soichiro, Palmer, Nicholette D., Pausova, Zdenka, Preda, Adrian, Quidé, Yann, Reay, William R., Roshchupkin, Gennady V., Schmidt, Reinhold, Schreiner, Pamela J., Setoh, Kazuya, Shapland, Chin Yang, Sidney, Stephen, St Pourcain, Beate, Stein, Jason L., Tabara, Yasuharu, Teumer, Alexander, Uhlmann, Anne, van der Lugt, Aad, Vernooij, Meike W., Werring, David J., Windham, B. Gwen, Witte, A. Veronica, Wittfeld, Katharina, Yang, Qiong, Yoshida, Kazumichi, Brunner, Han G., Le Grand, Quentin, Sim, Kang, Stein, Dan J., Bowden, Donald W., Cairns, Murray J., Hariri, Ahmad R., Cheung, Ching-Lung, Andersson, Sture, Villringer, Arno, Paus, Tomas, Cichon, Sven, Calhoun, Vince D., Crivello, Fabrice, Launer, Lenore J., White, Tonya, Koudstaal, Peter J., Houlden, Henry, Fornage, Myriam, Matsuda, Fumihiko, Grabe, Hans J., Ikram, M. Arfan, Debette, Stéphanie, Thompson, Paul M., Seshadri, Sudha, and Adams, Hieab H.H.
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- 2024
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31. Two neurostructural subtypes: results of machine learning on brain images from 4,291 individuals with schizophrenia
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Jiang, Yuchao, primary, Luo, Cheng, additional, Wang, Jijun, additional, Palaniyappan, Lena, additional, Chang, Xiao, additional, Xiang, Shitong, additional, Zhang, Jie, additional, Duan, Mingjun, additional, Huang, Huan, additional, Gaser, Christian, additional, Nemoto, Kiyotaka, additional, Miura, Kenichiro, additional, Hashimoto, Ryota, additional, Westlye, Lars T., additional, Richard, Genevieve, additional, Fernandez-Cabello, Sara, additional, Parker, Nadine, additional, Andreassen, Ole A., additional, Kircher, Tilo, additional, Nenadi?, Igor, additional, Stein, Frederike, additional, Thomas-Odenthal, Florian, additional, Teutenberg, Lea, additional, Usemann, Paula, additional, Dannlowski, Udo, additional, Hahn, Tim, additional, Grotegerd, Dominik, additional, Meinert, Susanne, additional, Lencer, Rebekka, additional, Tang, Yingying, additional, Zhang, Tianhong, additional, Li, Chunbo, additional, Yue, Weihua, additional, Zhang, Yuyanan, additional, Yu, Xin, additional, Zhou, Enpeng, additional, Lin, Ching-Po, additional, Tsai, Shih-Jen, additional, Rodrigue, Amanda L., additional, Glahn, David, additional, Pearlson, Godfrey, additional, Blangero, John, additional, Karuk, Andriana, additional, pomarol-Clotet, Edith, additional, Salvador, Raymond, additional, Fuentes-Claramonte, Paola, additional, angeles, Maria, additional, Spalletta, Gianfranco, additional, Piras, Fabrizio, additional, Vecchio, Daniela, additional, Banaj, Nerisa, additional, Cheng, Jingliang, additional, Liu, Zhening, additional, Yang, Jie, additional, Gonul, Ali Saffet, additional, Uslu, Ozgul, additional, Burhanoglu, Birce Begum, additional, Demir, Aslihan Uyar, additional, Rootes-Murdy, Kelly, additional, Calhoun, Vince D., additional, Sim, Kang, additional, Green, Melissa, additional, Quide, Yann, additional, Chung, Young Chul, additional, Kim, Woo-Sung, additional, Sponheim, Scott R., additional, Demro, Caroline, additional, Ramsay, Ian S., additional, Iasevoli, Felice, additional, Bartolomeis, Andrea de, additional, Barone, Annarita, additional, Ciccarelli, Mariateresa, additional, Brunetti, Arturo, additional, Cocozza, Sirio, additional, Pontillo, Giuseppe, additional, Tranfa, Mario, additional, Park, Min Tae M., additional, Kirschner, Matthias, additional, Georgiadis, Foivos, additional, Kaiser, Stefan, additional, Rheenen, Tamsyn Van, additional, Rossell, Susan, additional, Hughes, Matthew, additional, Woods, William, additional, Carruthers, Sean, additional, Sumner, Philip, additional, Ringin, Elysha, additional, Spaniel, Filip, additional, Skoch, Antonin, additional, Tomecek, David, additional, Homan, Philipp, additional, Homan, Stephanie, additional, Omlor, Wolfgang, additional, Cecere, Giacomo, additional, Nguyen, Dana D, additional, Preda, Adrian, additional, Thomopoulos, Sophia, additional, Jahanshad, Neda, additional, Cui, Long-Biao, additional, Yao, Dezhong, additional, Thompson, Paul M., additional, Turner, Jessica A., additional, van Erp, Theo G.M., additional, Cheng, Wei, additional, and Feng, Jianfeng, additional
- Published
- 2023
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32. 4D DYNAMIC SPATIAL BRAIN NETWORKS AT REST LINKED TO COGNITION SHOW ATYPICAL VARIABILITY AND COUPLING IN SCHIZOPHRENIA
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Pusuluri, Krishna, primary, Fu, Zening, additional, Miller, Robyn L., additional, Pearlson, Godfrey D, additional, Kochunov, Peter, additional, Van Erp, Theo G.M., additional, Iraji, Armin, additional, and Calhoun, Vince, additional
- Published
- 2023
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33. Ventricular enlargement and progressive reduction of cortical gray matter are linked in prodromal youth who develop psychosis
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Chung, Yoonho, Haut, Kristen M., He, George, van Erp, Theo G.M., McEwen, Sarah, Addington, Jean, Bearden, Carrie E., Cadenhead, Kristin, Cornblatt, Barbara, Mathalon, Daniel H., McGlashan, Thomas, Perkins, Diana, Seidman, Larry J., Tsuang, Ming, Walker, Elaine, Woods, Scott W., and Cannon, Tyrone D.
- Published
- 2017
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34. Childhood adversity impacts on brain subcortical structures relevant to depression
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Frodl, Thomas, Janowitz, Deborah, Schmaal, Lianne, Tozzi, Leonardo, Dobrowolny, Henrik, Stein, Dan J., Veltman, Dick J., Wittfeld, Katharina, van Erp, Theo G.M., Jahanshad, Neda, Block, Andrea, Hegenscheid, Katrin, Völzke, Henry, Lagopoulos, Jim, Hatton, Sean N., Hickie, Ian B., Frey, Eva Maria, Carballedo, Angela, Brooks, Samantha J., Vuletic, Daniella, Uhlmann, Anne, Veer, Ilya M., Walter, Henrik, Schnell, Knut, Grotegerd, Dominik, Arolt, Volker, Kugel, Harald, Schramm, Elisabeth, Konrad, Carsten, Zurowski, Bartosz, Baune, Bernhard T., van der Wee, Nic J.A., van Tol, Marie-Jose, Penninx, Brenda W.J.H., Thompson, Paul M., Hibar, Derrek P., Dannlowski, Udo, and Grabe, Hans J.
- Published
- 2017
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35. Multisite reliability of MR-based functional connectivity
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Noble, Stephanie, Scheinost, Dustin, Finn, Emily S., Shen, Xilin, Papademetris, Xenophon, McEwen, Sarah C., Bearden, Carrie E., Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Olvet, Doreen M., Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Seidman, Larry J., Thermenos, Heidi, Tsuang, Ming T., van Erp, Theo G.M., Walker, Elaine F., Hamann, Stephan, Woods, Scott W., Cannon, Tyrone D., and Constable, R. Todd
- Published
- 2017
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36. ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide
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Thompson, Paul M., Andreassen, Ole A., Arias-Vasquez, Alejandro, Bearden, Carrie E., Boedhoe, Premika S., Brouwer, Rachel M., Buckner, Randy L., Buitelaar, Jan K., Bulayeva, Kazima B., Cannon, Dara M., Cohen, Ronald A., Conrod, Patricia J., Dale, Anders M., Deary, Ian J., Dennis, Emily L., de Reus, Marcel A., Desrivieres, Sylvane, Dima, Danai, Donohoe, Gary, Fisher, Simon E., Fouche, Jean-Paul, Francks, Clyde, Frangou, Sophia, Franke, Barbara, Ganjgahi, Habib, Garavan, Hugh, Glahn, David C., Grabe, Hans J., Guadalupe, Tulio, Gutman, Boris A., Hashimoto, Ryota, Hibar, Derrek P., Holland, Dominic, Hoogman, Martine, Pol, Hilleke E. Hulshoff, Hosten, Norbert, Jahanshad, Neda, Kelly, Sinead, Kochunov, Peter, Kremen, William S., Lee, Phil H., Mackey, Scott, Martin, Nicholas G., Mazoyer, Bernard, McDonald, Colm, Medland, Sarah E., Morey, Rajendra A., Nichols, Thomas E., Paus, Tomas, Pausova, Zdenka, Schmaal, Lianne, Schumann, Gunter, Shen, Li, Sisodiya, Sanjay M., Smit, Dirk J.A., Smoller, Jordan W., Stein, Dan J., Stein, Jason L., Toro, Roberto, Turner, Jessica A., van den Heuvel, Martijn P., van den Heuvel, Odile L., van Erp, Theo G.M., van Rooij, Daan, Veltman, Dick J., Walter, Henrik, Wang, Yalin, Wardlaw, Joanna M., Whelan, Christopher D., Wright, Margaret J., and Ye, Jieping
- Published
- 2017
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37. Alterations in grey matter structure linked to frequency-specific cortico-subcortical connectivity in schizophrenia via multimodal data fusion
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Duda, Marlena, primary, Faghiri, Ashkan, additional, Belger, Aysenil, additional, Bustillo, Juan R., additional, Ford, Judith M., additional, Mathalon, Daniel H., additional, Mueller, Bryon A., additional, Pearlson, Godfrey D., additional, Potkin, Steven G., additional, Preda, Adrian, additional, Sui, Jing, additional, Van Erp, Theo G.M., additional, and Calhoun, Vince D., additional
- Published
- 2023
- Full Text
- View/download PDF
38. Neural Correlates of Positive and Negative Formal Thought Disorder in Individuals with Schizophrenia: An ENIGMA Schizophrenia Working Group Study
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Sharkey, Rachel J., primary, Bacon, Chelsea, additional, Peterson, Zeru, additional, Rootes-Murdy, Kelly, additional, Salvador, Raymond, additional, Pomarol-Clotet, Edith, additional, Karuk, Andriana, additional, Homan, Philipp, additional, Ji, Ellen, additional, Omlor, Wolfgang, additional, Homan, Stephanie, additional, Georgiadis, Foivos, additional, Kaiser, Stefan, additional, Kirschner, Matthias, additional, Ehrlich, Stefan, additional, Dannlowski, Udo, additional, Grotegerd, Dominik, additional, Goltermann, Janik, additional, Meinert, Susanne, additional, Kircher, Tilo, additional, Stein, Frederike, additional, Brosch, Katharina, additional, Krug, Axel, additional, Nenadić, Igor, additional, Sim, Kang, additional, Spalletta, Gianfranco, additional, Piras, Fabrizio, additional, Banaj, Nerisa, additional, Sponheim, Scott R, additional, Demro, Caroline, additional, Ramsay, Ian S, additional, King, Margaret, additional, Quidé, Yann, additional, Green, Melissa J., additional, Nguyen, Dana, additional, Preda, Adrian, additional, Calhoun, Vince D., additional, Turner, Jessica A., additional, van Erp, Theo G.M., additional, and Nickl-Jockschat, Thomas, additional
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- 2023
- Full Text
- View/download PDF
39. Pallidum and lateral ventricle volume enlargement in autism spectrum disorder
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Turner, Andia H., Greenspan, Kiefer S., and van Erp, Theo G.M.
- Published
- 2016
- Full Text
- View/download PDF
40. Heritability and reliability of automatically segmented human hippocampal formation subregions
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Whelan, Christopher D., Hibar, Derrek P., van Velzen, Laura S., Zannas, Anthony S., Carrillo-Roa, Tania, McMahon, Katie, Prasad, Gautam, Kelly, Sinéad, Faskowitz, Joshua, deZubiracay, Greig, Iglesias, Juan E., van Erp, Theo G.M., Frodl, Thomas, Martin, Nicholas G., Wright, Margaret J., Jahanshad, Neda, Schmaal, Lianne, Sämann, Philipp G., and Thompson, Paul M.
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- 2016
- Full Text
- View/download PDF
41. Neural Correlates of Positive and Negative Formal Thought Disorder in Individuals with Schizophrenia: An ENIGMA Schizophrenia Working Group Study
- Author
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Sharkey, Rachel J., Bacon, Chelsea, Peterson, Zeru, Rootes-Murdy, Kelly, Salvador, Raymond, Pomarol-Clotet, Edith, Karuk, Andriana, Homan, Philipp, Ji, Ellen, Omlor, Wolfgang, Homan, Stephanie, Georgiadis, Foivos, Kaiser, Stefan, Kirschner, Matthias, Ehrlich, Stefan, Dannlowski, Udo, Grotegerd, Dominik, Goltermann, Janik, Meinert, Susanne, Kircher, Tilo, Stein, Frederike, Brosch, Katharina, Krug, Axel, Nenadić, Igor, Sim, Kang, Spalletta, Gianfranco, Piras, Fabrizio, Banaj, Nerisa, Sponheim, Scott R, Demro, Caroline, Ramsay, Ian S, King, Margaret, Quidé, Yann, Green, Melissa J., Nguyen, Dana, Preda, Adrian, Calhoun, Vince D., Turner, Jessica A., van Erp, Theo G.M., and Nickl-Jockschat, Thomas
- Subjects
Article - Abstract
Formal thought disorder (FTD) is a key clinical factor in schizophrenia, but the neurobiological underpinnings remain unclear. In particular, relationship between FTD symptom dimensions and patterns of regional brain volume deficiencies in schizophrenia remain to be established in large cohorts. Even less is known about the cellular basis of FTD. Our study addresses these major obstacles based on a large multi-site cohort through the ENIGMA Schizophrenia Working Group (752 individuals with schizophrenia and 1256 controls), to unravel the neuroanatomy of positive, negative and total FTD in schizophrenia and their cellular bases. We used virtual histology tools to relate brain structural changes associated with FTD to cellular distributions in cortical regions. We identified distinct neural networks for positive and negative FTD. Both networks encompassed fronto-occipito-amygdalar brain regions, but negative FTD showed a relative sparing of orbitofrontal cortical thickness, while positive FTD also affected lateral temporal cortices. Virtual histology identified distinct transcriptomic fingerprints associated for both symptom dimensions. Negative FTD was linked to neuronal and astrocyte fingerprints, while positive FTD was also linked to microglial cell types. These findings relate different dimensions of FTD to distinct brain structural changes and their cellular underpinnings, improve our mechanistic understanding of these key psychotic symptoms.
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- 2023
42. The Function Biomedical Informatics Research Network Data Repository
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Keator, David B., van Erp, Theo G.M., Turner, Jessica A., Glover, Gary H., Mueller, Bryon A., Liu, Thomas T., Voyvodic, James T., Rasmussen, Jerod, Calhoun, Vince D., Lee, Hyo Jong, Toga, Arthur W., McEwen, Sarah, Ford, Judith M., Mathalon, Daniel H., Diaz, Michele, O'Leary, Daniel S., Jeremy Bockholt, H., Gadde, Syam, Preda, Adrian, Wible, Cynthia G., Stern, Hal S., Belger, Aysenil, McCarthy, Gregory, Ozyurt, Burak, and Potkin, Steven G.
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- 2016
- Full Text
- View/download PDF
43. Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
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Schijven, Dick, Postema, Merel C., Fukunaga, Masaki, Matsumoto, Junya, Miura, Kenichiro, de Zwarte, Sonja M.C., van Haren, Neeltje E.M., Cahn, Wiepke, Hulshoff Pol, Hilleke E., Kahn, René S., Ayesa-Arriola, Rosa, Ortiz-García de la Foz, Víctor, Tordesillas-Gutierrez, Diana, Vázquez-Bourgon, Javier, Crespo-Facorro, Benedicto, Alnæs, Dag, Dahl, Andreas, Westlye, Lars T., Agartz, Ingrid, Andreassen, Ole A., Jönsson, Erik G., Kochunov, Peter, Bruggemann, Jason M., Catts, Stanley V., Michie, Patricia T., Mowry, Bryan J., Quidé, Yann, Rasser, Paul E., Schall, Ulrich, Scott, Rodney J., Carr, Vaughan J., Green, Melissa J., Henskens, Frans A., Loughland, Carmel M., Pantelis, Christos, Weickert, Cynthia Shannon, Weickert, Thomas W., de Haan, Lieuwe, Brosch, Katharina, Pfarr, Julia Katharina, Ringwald, Kai G., Stein, Frederike, Jansen, Andreas, Kircher, Tilo T.J., Nenadić, Igor, Krämer, Bernd, Gruber, Oliver, Satterthwaite, Theodore D., Bustillo, Juan, Mathalon, Daniel H., Preda, Adrian, Calhoun, Vince D., Ford, Judith M., Potkin, Steven G., Chen, Jingxu, Tan, Yunlong, Wang, Zhiren, Xiang, Hong, Fan, Fengmei, Bernardoni, Fabio, Ehrlich, Stefan, Fuentes-Claramonte, Paola, Garcia-Leon, Maria Angeles, Guerrero-Pedraza, Amalia, Salvador, Raymond, Sarró, Salvador, Pomarol-Clotet, Edith, Ciullo, Valentina, Piras, Fabrizio, Vecchio, Daniela, Banaj, Nerisa, Spalletta, Gianfranco, Michielse, Stijn, van Amelsvoort, Therese, Dickie, Erin W., Voineskos, Aristotle N., Sim, Kang, Ciufolini, Simone, Dazzan, Paola, Murray, Robin M., Kim, Woo Sung, Chung, Young Chul, Andreou, Christina, Schmidt, André, Borgwardt, Stefan, McIntosh, Andrew M., Whalley, Heather C., Lawrie, Stephen M., du Plessis, Stefan, Luckhoff, Hilmar K., Scheffler, Freda, Emsley, Robin, Grotegerd, Dominik, Lencer, Rebekka, Dannlowski, Udo, Edmond, Jesse T., Rootes-Murdy, Kelly, Stephen, Julia M., Mayer, Andrew R., Antonucci, Linda A., Fazio, Leonardo, Pergola, Giulio, Bertolino, Alessandro, Díaz-Caneja, Covadonga M., Janssen, Joost, Lois, Noemi G., Arango, Celso, Tomyshev, Alexander S., Lebedeva, Irina, Cervenka, Simon, Sellgren, Carl M., Georgiadis, Foivos, Kirschner, Matthias, Kaiser, Stefan, Hajek, Tomas, Skoch, Antonin, Spaniel, Filip, Kim, Minah, Kwak, Yoo Bin, Oh, Sanghoon, Kwon, Jun Soo, James, Anthony, Bakker, Geor, Knöchel, Christian, Stäblein, Michael, Oertel, Viola, Uhlmann, Anne, Howells, Fleur M., Stein, Dan J., Temmingh, Henk S., Diaz-Zuluaga, Ana M., Pineda-Zapata, Julian A., López-Jaramillo, Carlos, Homan, Stephanie, Ji, Ellen, Surbeck, Werner, Homan, Philipp, Fisher, Simon E., Franke, Barbara, Glahn, David C., Gur, Ruben C., Hashimoto, Ryota, Jahanshad, Neda, Luders, Eileen, Medland, Sarah E., Thompson, Paul M., Turner, Jessica A., van Erp, Theo G.M., Francks, Clyde, Schijven, Dick, Postema, Merel C., Fukunaga, Masaki, Matsumoto, Junya, Miura, Kenichiro, de Zwarte, Sonja M.C., van Haren, Neeltje E.M., Cahn, Wiepke, Hulshoff Pol, Hilleke E., Kahn, René S., Ayesa-Arriola, Rosa, Ortiz-García de la Foz, Víctor, Tordesillas-Gutierrez, Diana, Vázquez-Bourgon, Javier, Crespo-Facorro, Benedicto, Alnæs, Dag, Dahl, Andreas, Westlye, Lars T., Agartz, Ingrid, Andreassen, Ole A., Jönsson, Erik G., Kochunov, Peter, Bruggemann, Jason M., Catts, Stanley V., Michie, Patricia T., Mowry, Bryan J., Quidé, Yann, Rasser, Paul E., Schall, Ulrich, Scott, Rodney J., Carr, Vaughan J., Green, Melissa J., Henskens, Frans A., Loughland, Carmel M., Pantelis, Christos, Weickert, Cynthia Shannon, Weickert, Thomas W., de Haan, Lieuwe, Brosch, Katharina, Pfarr, Julia Katharina, Ringwald, Kai G., Stein, Frederike, Jansen, Andreas, Kircher, Tilo T.J., Nenadić, Igor, Krämer, Bernd, Gruber, Oliver, Satterthwaite, Theodore D., Bustillo, Juan, Mathalon, Daniel H., Preda, Adrian, Calhoun, Vince D., Ford, Judith M., Potkin, Steven G., Chen, Jingxu, Tan, Yunlong, Wang, Zhiren, Xiang, Hong, Fan, Fengmei, Bernardoni, Fabio, Ehrlich, Stefan, Fuentes-Claramonte, Paola, Garcia-Leon, Maria Angeles, Guerrero-Pedraza, Amalia, Salvador, Raymond, Sarró, Salvador, Pomarol-Clotet, Edith, Ciullo, Valentina, Piras, Fabrizio, Vecchio, Daniela, Banaj, Nerisa, Spalletta, Gianfranco, Michielse, Stijn, van Amelsvoort, Therese, Dickie, Erin W., Voineskos, Aristotle N., Sim, Kang, Ciufolini, Simone, Dazzan, Paola, Murray, Robin M., Kim, Woo Sung, Chung, Young Chul, Andreou, Christina, Schmidt, André, Borgwardt, Stefan, McIntosh, Andrew M., Whalley, Heather C., Lawrie, Stephen M., du Plessis, Stefan, Luckhoff, Hilmar K., Scheffler, Freda, Emsley, Robin, Grotegerd, Dominik, Lencer, Rebekka, Dannlowski, Udo, Edmond, Jesse T., Rootes-Murdy, Kelly, Stephen, Julia M., Mayer, Andrew R., Antonucci, Linda A., Fazio, Leonardo, Pergola, Giulio, Bertolino, Alessandro, Díaz-Caneja, Covadonga M., Janssen, Joost, Lois, Noemi G., Arango, Celso, Tomyshev, Alexander S., Lebedeva, Irina, Cervenka, Simon, Sellgren, Carl M., Georgiadis, Foivos, Kirschner, Matthias, Kaiser, Stefan, Hajek, Tomas, Skoch, Antonin, Spaniel, Filip, Kim, Minah, Kwak, Yoo Bin, Oh, Sanghoon, Kwon, Jun Soo, James, Anthony, Bakker, Geor, Knöchel, Christian, Stäblein, Michael, Oertel, Viola, Uhlmann, Anne, Howells, Fleur M., Stein, Dan J., Temmingh, Henk S., Diaz-Zuluaga, Ana M., Pineda-Zapata, Julian A., López-Jaramillo, Carlos, Homan, Stephanie, Ji, Ellen, Surbeck, Werner, Homan, Philipp, Fisher, Simon E., Franke, Barbara, Glahn, David C., Gur, Ruben C., Hashimoto, Ryota, Jahanshad, Neda, Luders, Eileen, Medland, Sarah E., Thompson, Paul M., Turner, Jessica A., van Erp, Theo G.M., and Francks, Clyde
- Abstract
Left-right asymmetry is an important organizing feature of the healthy brain that may be altered in schizophrenia, but most studies have used relatively small samples and heterogeneous approaches, resulting in equivocal findings. We carried out the largest case-control study of structural brain asymmetries in schizophrenia, with MRI data from 5,080 affected individuals and 6,015 controls across 46 datasets, using a single image analysis protocol. Asymmetry indexes were calculated for global and regional cortical thickness, surface area, and subcortical volume measures. Differences of asymmetry were calculated between affected individuals and controls per dataset, and effect sizes were meta-analyzed across datasets. Small average case-control differences were observed for thickness asymmetries of the rostral anterior cingulate and the middle temporal gyrus, both driven by thinner left-hemispheric cortices in schizophrenia. Analyses of these asymmetries with respect to the use of antipsychotic medication and other clinical variables did not show any significant associations. Assessment of age- and sex-specific effects revealed a stronger average leftward asymmetry of pallidum volume between older cases and controls. Case-control differences in a multivariate context were assessed in a subset of the data (N = 2,029), which revealed that 7% of the variance across all structural asymmetries was explained by case-control status. Subtle case-control differences of brain macrostructural asymmetry may reflect differences at the molecular, cytoarchitectonic, or circuit levels that have functional relevance for the disorder. Reduced left middle temporal cortical thickness is consistent with altered left-hemisphere language network organization in schizophrenia.
- Published
- 2023
44. Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium
- Author
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MGGZ, Brain, Zhu, Xi, Kim, Yoojean, Ravid, Orren, He, Xiaofu, Suarez-Jimenez, Benjamin, Zilcha-Mano, Sigal, Lazarov, Amit, Lee, Seonjoo, Abdallah, Chadi G., Angstadt, Michael, Averill, Christopher L., Baird, C. Lexi, Baugh, Lee A., Blackford, Jennifer U., Bomyea, Jessica, Bruce, Steven E., Bryant, Richard A., Cao, Zhihong, Choi, Kyle, Cisler, Josh, Cotton, Andrew S., Daniels, Judith K., Davenport, Nicholas D., Davidson, Richard J., DeBellis, Michael D., Dennis, Emily L., Densmore, Maria, deRoon-Cassini, Terri, Disner, Seth G., Hage, Wissam El, Etkin, Amit, Fani, Negar, Fercho, Kelene A., Fitzgerald, Jacklynn, Forster, Gina L., Frijling, Jessie L., Geuze, Elbert, Gonenc, Atilla, Gordon, Evan M., Gruber, Staci, Grupe, Daniel W., Guenette, Jeffrey P., Haswell, Courtney C., Herringa, Ryan J., Herzog, Julia, Hofmann, David Bernd, Hosseini, Bobak, Hudson, Anna R., Huggins, Ashley A., Ipser, Jonathan C., Jahanshad, Neda, Jia-Richards, Meilin, Jovanovic, Tanja, Kaufman, Milissa L., Kennis, Mitzy, King, Anthony, Kinzel, Philipp, Koch, Saskia B.J., Koerte, Inga K., Koopowitz, Sheri M., Korgaonkar, Mayuresh S., Krystal, John H., Lanius, Ruth, Larson, Christine L., Lebois, Lauren A.M., Li, Gen, Liberzon, Israel, Lu, Guang Ming, Luo, Yifeng, Magnotta, Vincent A., Manthey, Antje, Maron-Katz, Adi, May, Geoffery, McLaughlin, Katie, Mueller, Sven C., Nawijn, Laura, Nelson, Steven M., Neufeld, Richard W.J., Nitschke, Jack B., O'Leary, Erin M., Olatunji, Bunmi O., Olff, Miranda, Peverill, Matthew, Phan, K. Luan, Qi, Rongfeng, Quidé, Yann, Rektor, Ivan, Ressler, Kerry, Riha, Pavel, Ross, Marisa, Rosso, Isabelle M., Salminen, Lauren E., Sambrook, Kelly, Schmahl, Christian, Shenton, Martha E., Sheridan, Margaret, Shih, Chiahao, Sicorello, Maurizio, Sierk, Anika, Simmons, Alan N., Simons, Raluca M., Simons, Jeffrey S., Sponheim, Scott R., Stein, Murray B., Stein, Dan J., Stevens, Jennifer S., Straube, Thomas, Sun, Delin, Théberge, Jean, Thompson, Paul M., Thomopoulos, Sophia I., van der Wee, Nic J.A., van der Werff, Steven J.A., van Erp, Theo G.M., van Rooij, Sanne J.H., van Zuiden, Mirjam, Varkevisser, Tim, Veltman, Dick J., Vermeiren, Robert R.J.M., Walter, Henrik, Wang, Li, Wang, Xin, Weis, Carissa, Winternitz, Sherry, Xie, Hong, Zhu, Ye, Wall, Melanie, Neria, Yuval, Morey, Rajendra A., MGGZ, Brain, Zhu, Xi, Kim, Yoojean, Ravid, Orren, He, Xiaofu, Suarez-Jimenez, Benjamin, Zilcha-Mano, Sigal, Lazarov, Amit, Lee, Seonjoo, Abdallah, Chadi G., Angstadt, Michael, Averill, Christopher L., Baird, C. Lexi, Baugh, Lee A., Blackford, Jennifer U., Bomyea, Jessica, Bruce, Steven E., Bryant, Richard A., Cao, Zhihong, Choi, Kyle, Cisler, Josh, Cotton, Andrew S., Daniels, Judith K., Davenport, Nicholas D., Davidson, Richard J., DeBellis, Michael D., Dennis, Emily L., Densmore, Maria, deRoon-Cassini, Terri, Disner, Seth G., Hage, Wissam El, Etkin, Amit, Fani, Negar, Fercho, Kelene A., Fitzgerald, Jacklynn, Forster, Gina L., Frijling, Jessie L., Geuze, Elbert, Gonenc, Atilla, Gordon, Evan M., Gruber, Staci, Grupe, Daniel W., Guenette, Jeffrey P., Haswell, Courtney C., Herringa, Ryan J., Herzog, Julia, Hofmann, David Bernd, Hosseini, Bobak, Hudson, Anna R., Huggins, Ashley A., Ipser, Jonathan C., Jahanshad, Neda, Jia-Richards, Meilin, Jovanovic, Tanja, Kaufman, Milissa L., Kennis, Mitzy, King, Anthony, Kinzel, Philipp, Koch, Saskia B.J., Koerte, Inga K., Koopowitz, Sheri M., Korgaonkar, Mayuresh S., Krystal, John H., Lanius, Ruth, Larson, Christine L., Lebois, Lauren A.M., Li, Gen, Liberzon, Israel, Lu, Guang Ming, Luo, Yifeng, Magnotta, Vincent A., Manthey, Antje, Maron-Katz, Adi, May, Geoffery, McLaughlin, Katie, Mueller, Sven C., Nawijn, Laura, Nelson, Steven M., Neufeld, Richard W.J., Nitschke, Jack B., O'Leary, Erin M., Olatunji, Bunmi O., Olff, Miranda, Peverill, Matthew, Phan, K. Luan, Qi, Rongfeng, Quidé, Yann, Rektor, Ivan, Ressler, Kerry, Riha, Pavel, Ross, Marisa, Rosso, Isabelle M., Salminen, Lauren E., Sambrook, Kelly, Schmahl, Christian, Shenton, Martha E., Sheridan, Margaret, Shih, Chiahao, Sicorello, Maurizio, Sierk, Anika, Simmons, Alan N., Simons, Raluca M., Simons, Jeffrey S., Sponheim, Scott R., Stein, Murray B., Stein, Dan J., Stevens, Jennifer S., Straube, Thomas, Sun, Delin, Théberge, Jean, Thompson, Paul M., Thomopoulos, Sophia I., van der Wee, Nic J.A., van der Werff, Steven J.A., van Erp, Theo G.M., van Rooij, Sanne J.H., van Zuiden, Mirjam, Varkevisser, Tim, Veltman, Dick J., Vermeiren, Robert R.J.M., Walter, Henrik, Wang, Li, Wang, Xin, Weis, Carissa, Winternitz, Sherry, Xie, Hong, Zhu, Ye, Wall, Melanie, Neria, Yuval, and Morey, Rajendra A.
- Published
- 2023
45. Five negative symptom domains are differentially associated with resting state amplitude of low frequency fluctuations in Schizophrenia
- Author
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Cheon, Eun-jin, primary, Male, Alie G., additional, Gao, Bingchen, additional, Adhikari, Bhim M., additional, Edmond, Jesse T., additional, Hare, Stephanie M., additional, Belger, Aysenil, additional, Potkin, Steven G., additional, Bustillo, Juan R., additional, Mathalon, Daniel H., additional, Ford, Judith M., additional, Lim, Kelvin O., additional, Mueller, Bryon A., additional, Preda, Adrian, additional, O'Leary, Daniel, additional, Strauss, Gregory P., additional, Ahmed, Anthony O., additional, Thompson, Paul M., additional, Jahanshad, Neda, additional, Kochunov, Peter, additional, Calhoun, Vince D., additional, Turner, Jessica A., additional, and van Erp, Theo G.M., additional
- Published
- 2023
- Full Text
- View/download PDF
46. Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study
- Author
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Georgiadis, Foivos, primary, Larivière, Sara, additional, Glahn, David, additional, Hong, L. Elliot, additional, Kochunov, Peter, additional, Mowry, Bryan, additional, Loughland, Carmel, additional, Pantelis, Christos, additional, Henskens, Frans A., additional, Green, Melissa J., additional, Cairns, Murray J., additional, Michie, Patricia T, additional, Rasser, Paul E., additional, Tooney, Paul, additional, Scott, Rodney J., additional, Catts, Stanley, additional, Schall, Ulrich, additional, Carr, Vaughan, additional, Quidé, Yann, additional, Krug, Axel, additional, Stein, Frederike, additional, Nenadić, Igor, additional, Brosch, Katharina, additional, Kircher, Tilo, additional, Gur, Raquel, additional, Gur, Ruben, additional, Satterthwaite, Theodore D., additional, Karuk, Andriana, additional, Clotet, Edith Pomarol-, additional, Radua, Joaquim, additional, Fuentes-Claramonte, Paola, additional, Salvador, Raymond, additional, Spalletta, Gianfranco, additional, Voineskos, Aristotle, additional, Sim, Kang, additional, Crespo-Facorro, Benedicto, additional, Gutiérrez, Diana Tordesillas, additional, Ehrlich, Stefan, additional, Crossley, Nicolas, additional, Grotegerd, Dominik, additional, Repple, Jonathan, additional, Lencer, Rebekka, additional, Dannlowski, Udo, additional, Calhoun, Vince, additional, Demro, Caroline, additional, Ramsay, Ian S., additional, Sponheim, Scott R., additional, Schmidt, Andre, additional, Borgwardt, Stefan, additional, Tomyshev, Alexander S., additional, Lebedeva, Irina, additional, Hoschl, Cyril, additional, Spaniel, Filip, additional, Preda, Adrian, additional, Nguyen, Dana, additional, Uhlmann, Anne, additional, Stein, Dan J, additional, Howells, Fleur M, additional, Temmingh, Henk S., additional, Diaz Zuluaga, Ana M., additional, Jaramillo, Carlos López, additional, Iasevoli, Felice, additional, Ji, Ellen, additional, Homan, Stephanie, additional, Omlor, Wolfgang, additional, Homan, Philipp, additional, Kaiser, Stefan, additional, Seifritz, Erich, additional, Misic, Bratislav, additional, Valk, Sofie L., additional, Thompson, Paul, additional, van Erp, Theo G.M., additional, Turner, Jessica, additional, Bernhardt, Boris, additional, and Kirschner, Matthias, additional
- Published
- 2023
- Full Text
- View/download PDF
47. Neuropsychological profile in adult schizophrenia measured with the CMINDS
- Author
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van Erp, Theo G.M., Preda, Adrian, Turner, Jessica A., Callahan, Shawn, Calhoun, Vince D., Bustillo, Juan R., Lim, Kelvin O., Mueller, Bryon, Brown, Gregory G., Vaidya, Jatin G., McEwen, Sarah, Belger, Aysenil, Voyvodic, James, Mathalon, Daniel H., Nguyen, Dana, Ford, Judith M., and Potkin, Steven G.
- Published
- 2015
- Full Text
- View/download PDF
48. Progressive Reduction in Cortical Thickness as Psychosis Develops: A Multisite Longitudinal Neuroimaging Study of Youth at Elevated Clinical Risk
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Cannon, Tyrone D., Chung, Yoonho, He, George, Sun, Daqiang, Jacobson, Aron, van Erp, Theo G.M., McEwen, Sarah, Addington, Jean, Bearden, Carrie E., Cadenhead, Kristin, Cornblatt, Barbara, Mathalon, Daniel H., McGlashan, Thomas, Perkins, Diana, Jeffries, Clark, Seidman, Larry J., Tsuang, Ming, Walker, Elaine, Woods, Scott W., and Heinssen, Robert
- Published
- 2015
- Full Text
- View/download PDF
49. A Novel Neighborhood Rough Set-Based Feature Selection Method and Its Application to Biomarker Identification of Schizophrenia
- Author
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Xing, Ying, primary, Kochunov, Peter, additional, van Erp, Theo G.M., additional, Ma, Tianzhou, additional, Calhoun, Vince D., additional, and Du, Yuhui, additional
- Published
- 2023
- Full Text
- View/download PDF
50. Reliability of functional magnetic resonance imaging activation during working memory in a multi-site study: Analysis from the North American Prodrome Longitudinal Study
- Author
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Forsyth, Jennifer K., McEwen, Sarah C., Gee, Dylan G., Bearden, Carrie E., Addington, Jean, Goodyear, Brad, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Olvet, Doreen M., Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Seidman, Larry J., Thermenos, Heidi W., Tsuang, Ming T., van Erp, Theo G.M., Walker, Elaine F., Hamann, Stephan, Woods, Scott W., Qiu, Maolin, and Cannon, Tyrone D.
- Published
- 2014
- Full Text
- View/download PDF
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