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723 results on '"van Dijk, F."'

3. Low Phase Noise InP-SiN Hybrid Mode-Locked Laser working at 3.64 GHz

Author

Duport, F., primary, Boust, S., additional, Ibrahimi, Y., additional, Baili, G., additional, Dande, G., additional, Wilmart, Q., additional, Garcia, S., additional, Fortin, C., additional, Garreau, A., additional, Paret, J-F., additional, Mekhazni, K., additional, Gariah, H., additional, Charbonnier, P., additional, Blache, F., additional, and Van Dijk, F., additional

Published
2023
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4. Experimental investigation of relaxation oscillations resonance in mode-locked Fabry-Perot semiconductor lasers

Author

Roncin, Vincent, Poëtte, Julien, Hayau, Jean-François, Besnard, Pascal, Simon, Jean-Claude, Van Dijk, F., Shen, Alexandre, and Duan, Guang-Hua

Subjects
Physics - Optics
Abstract

We propose in this communication an experimental study of the relaxation oscillations behavior in mode-locked lasers. The semiconductor self-pulsating laser diode is composed by two gain sections, without saturable absorber. It is made of bulk structure and designed for optical telecommunication applications. This specific device allows two different regimes of optical modulation: the first one corresponds to the resonance of the relaxation oscillations and the second one, to the mode-locking regime at FSR value. This singular behavior leads us to characterize the self-pulsations which are coexisting in the laser and to describe two regimes of output modulation: the first one appears thanks to the resonance of the oscillation relaxation and the other one corresponds to the FSR of the Fabry-Perot laser at 40 GHz., Comment: poster session, SPIE Photonics Europe, Strasbourg : France (2008)

Published
2014
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8. Non-oral manifestations in adults with a clinical and molecularly confirmed diagnosis of periodontal Ehlers-Danlos syndrome

Author

Angwin, C., primary, Zschocke, J., additional, Kammin, T., additional, Björck, E., additional, Bowen, J., additional, Brady, A. F., additional, Burns, H., additional, Cummings, C., additional, Gardner, R., additional, Ghali, N., additional, Gröbner, R., additional, Harris, J., additional, Higgins, M., additional, Johnson, D., additional, Lepperdinger, U., additional, Milnes, D., additional, Pope, F. M., additional, Sehra, R., additional, Kapferer-Seebacher, I., additional, Sobey, G., additional, and Van Dijk, F. S., additional

Published
2023
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11. Behavioural Phenotype in Borjeson-Forssman-Lehmann Syndrome

Author

de Winter, C. F., van Dijk, F., and Stolker, J. J.

Abstract

Background: Borjeson-Forssman-Lehmann syndrome (BFLs) is an X-linked inherited disorder characterised by unusual facial features, abnormal fat distribution and intellectual disability. As many genetically determined disorders are characterised not only by physical features but also by specific behaviour, we studied whether a specific behavioural phenotype exists in BFLs. Methods: We studied in detail the behaviour of four molecularly proven BFLs patients, and reviewed available literature on BFLs specifically for behavioural characteristics. Results: Behaviour in persons with BFLs is in general friendly, but can be challenging with externalising and thrill-seeking features. Social skills are good. However, variation among patients is wide. Three patients from a single family showed expressed hypersexual behaviour. This was not present in other patients. Conclusion: In BFLs a specific behavioural phenotype exists and in behaviour general is challenging besides a friendly habit. Within single families more problematic behaviour may occur. Further behavioural and molecular analysis of a larger group of patients is warranted to determine whether a genotype-behavioural phenotype correlation exists.

Published
2009
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12. De Persoonlijke Antipsychotica Keuzewijzer

Author

van Dijk, F. A., de Haan, L., Schirmbeck, N. F., Blankers, M., Adult Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Complex Trait Genetics, and Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep

Abstract

BACKGROUND: More than half of the patients suffering from a first psychotic episode withdraw from antipsychotic medication within the first year of treatment. Shared decision making could enhance the therapeutic relationship and thus adherence. AIM: To describe an online decision aid for the selection of antipsychotic medication: the Personal Antipsychotic Choice Index (www.pakwijzer.nl). METHOD: Per effect and side effect, the 15 most commonly prescribed antipsychotics in the Netherlands have been ranked on the basis of data on the magnitude of a desired effect and the chance of a side effect, based on a systematic literature study. We assigned scores to antipsychotics for each desired and undesired effect and processed these scores in an algorithm. A personal ranking of antipsychotics is calculated based on the value that patients attach to these effects. RESULTS: These desired and undesired criteria used are rated in the PACindex: effectiveness concerning psychotic, depressive and cognitive symptoms, weight gain, sexual dysfunction, drowsiness, hypersomnia, extrapyramidal symptoms, anticholinergic adverse effects, hypersalivation, nausea, dizziness, energy loss, blunted affect/less need for companionship. High level evidence was available for ranking weight gain, sexual dysfunction, menstrual disorders, extrapyramidal symptoms and effectiveness on psychotic symptoms. We used lower level evidence ranking the remaining criteria. CONCLUSION: A ready applicable online choixe index for the use of an antipsychotic agent has been developed and put into use. The PACindex could be updated when new evidence of new antipsychotics became available..

Published
2022

14. The Routine posTsuRgical Anesthesia visit to improve patient outComE (TRACE) study: lessons learned

Author

Buhre, Wolfgang F.F.A., de Korte-de Boer, Dianne, Boer, Christa, Stolze, Annick, Posthuma, Linda M., Smit-Fun, Valérie M., van Kuijk, Sander, Hollmann, Markus W., Noordzij, Peter G., Rinia, Myra, Hering, Jens-Peter, Veld, Bas in ‘t, Scheffer, Gert-Jan, Dirksen, Carmen, Boermeester, Marja, Bonjer, Jaap, Dejong, Cees, Breel, J.S., Bouw, T., van Dijk, F., Geurts, J., Glas, W., van Gorp, R., Jwair, A., Koca, F., Lange, I., Preckel, B., van Roy, J.P., Theunissen, M., Wensing, A.G.C.L., and Werger, A.

Published
2021
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16. The Routine posTsuRgical Anesthesia visit to improve patient outComE (TRACE) study: lessons learned

Author

Hollmann, Markus W., primary, de Korte-de Boer, Dianne, additional, Boer, Christa, additional, Buhre, Wolfgang F.F.A., additional, Stolze, Annick, additional, Posthuma, Linda M., additional, Smit-Fun, Valérie M., additional, van Kuijk, Sander, additional, Hollmann, Markus W., additional, Noordzij, Peter G., additional, Rinia, Myra, additional, Hering, Jens-Peter, additional, Veld, Bas in ‘t, additional, Scheffer, Gert-Jan, additional, Dirksen, Carmen, additional, Boermeester, Marja, additional, Bonjer, Jaap, additional, Dejong, Cees, additional, Breel, J.S., additional, Bouw, T., additional, van Dijk, F., additional, Geurts, J., additional, Glas, W., additional, van Gorp, R., additional, Jwair, A., additional, Koca, F., additional, Lange, I., additional, Preckel, B., additional, van Roy, J.P., additional, Theunissen, M., additional, Wensing, A.G.C.L., additional, and Werger, A., additional

Published
2021
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23. Epilogue

Author

Swaen, G. and Van Dijk, F.

Published
2003

30. Skewed X-inactivation is common in the general female population

Author

Shvetsova, E, Sofronova, A, Monajemi, R, Gagalova, K, Draisma, HHM, White, SJ, Santen, GWE, Lopes, SMCDS, Heijmans, BT, Van Meurs, J, Jansen, R, Franke, L, Kielbasa, SM, Den Dunnen, JT, 't Hoen, PAC, Boomsma, DI, Pool, R, Van Dongen, J, Hottenga, JJ, Van Greevenbroek, MMJ, Da Stehouwer, C, Van der Kallen, CJH, Schalkwijk, CG, Wijmenga, C, Zhernakova, S, Tigchelaar, EF, Slagboom, PE, Beekman, M, Deelen, J, Van Heemst, D, Veldink, JH, Van den Berg, LH, Van Duijn, CM, Hofman, BA, Uitterlinden, AG, Jhamai, PM, Verbiest, M, Suchiman, HED, Verkerk, M, Van der Breggen, R, Van Rooij, J, Lakenberg, N, Mei, H, Bot, J, Zhernakova, DV, 't Hof, PV, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, MJ, Van Iterson, M, Van Dijk, F, Van Galen, M, Arindrarto, W, Swertz, MA, Van Zwet, EW, Isaacs, A, Francioli, LC, Menelaou, A, Pulit, SL, Palamara, PF, Elbers, CC, Neerincx, PB, Ye, K, Guryev, V, Kloosterman, WP, Abdellaoui, A, Van Leeuwen, EM, Van Oven, M, Li, M, Laros, JF, Karssen, LC, Kanterakis, A, Amin, N, Lameijer, EW, Kattenberg, M, Dijkstra, M, Byelas, H, Van Setten, J, Van Schaik, BD, Nijman, IJ, Renkens, I, Marschall, T, Schonhuth, A, Hehir-Kwa, JY, Handsaker, RE, Polak, P, Sohail, M, Vuzman, D, Hormozdiari, F, Van Enckevort, D, Koval, V, Moed, MH, Van der Velde, KJ, Rivadeneira, F, Estrada, K, Medina-Gomez, C, McCarroll, SA, De Craen, AJ, Suchiman, HE, Oostra, B, Willemsen, G, Platteel, M, Pitts, SJ, Potluri, S, Sundar, P, Cox, DR, Sunyaev, SR, Stoneking, M, De Knijff, P, Kayser, M, Li, Q, Li, Y, Du, Y, Chen, R, Cao, H, Li, N, Cao, S, Wang, J, Bovenberg, JA, Pe'er, I, Van Ommen, GJ, De Bakker, PI, Consortium, Bios, Consortium, Gonl, BIOS consortium, GoNL consortium, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Groningen Research Institute for Asthma and COPD (GRIAC), Stem Cell Aging Leukemia and Lymphoma (SALL), Epidemiology and Data Science, AII - Inflammatory diseases, APH - Methodology, Experimental Immunology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Personalized Medicine, Biological Psychology, APH - Mental Health, APH - Health Behaviors & Chronic Diseases, RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, Interne Geneeskunde, RS: CARIM - R3 - Vascular biology, MUMC+: MA Reumatologie (9), MUMC+: MA Nefrologie (9), MUMC+: MA Medische Oncologie (9), MUMC+: MA Hematologie (9), MUMC+: MA Maag Darm Lever (9), MUMC+: MA Endocrinologie (9), MUMC+: HVC Pieken Maastricht Studie (9), RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, MUMC+: MA Interne Geneeskunde (3), RS: Carim - B01 Blood proteins & engineering, RS: FHML MaCSBio, RS: CARIM - R1 - Thrombosis and haemostasis, RS: CARIM - R1.01 - Blood proteins & engineering, Biochemie, Psychiatry, VU University medical center, Pediatric surgery, Amsterdam Reproduction & Development (AR&D), Internal Medicine, Epidemiology, Genetic Identification, and Clinical Genetics

Subjects
Netherlands Twin Register (NTR), Male, 0301 basic medicine, Receptors, Cytoplasmic and Nuclear/genetics, CHROMOSOME-INACTIVATION, BIOS consortium, Receptors, Cytoplasmic and Nuclear, Septins/genetics, Population genetics, GoNL consortium, Population/genetics, Negative selection, 0302 clinical medicine, X Chromosome Inactivation, Receptors, Non-U.S. Gov't, Genetics (clinical), Netherlands, Genetics & Heredity, Genetics, education.field_of_study, Membrane Glycoproteins, Dosage compensation, DMD LOCUS, Research Support, Non-U.S. Gov't, Receptors, Peptide/genetics, Intracellular Signaling Peptides and Proteins, Peptide/genetics, Single Nucleotide, CARRIERS, TRANSLOCATION, VARIABILITY, Female, Life Sciences & Biomedicine, EXPRESSION, Biochemistry & Molecular Biology, Receptors, Peptide, Population, ADRENOLEUKODYSTROPHY, Biology, Research Support, Polymorphism, Single Nucleotide, Article, X-inactivation, DUCHENNE MUSCULAR-DYSTROPHY, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Journal Article, Humans, Polymorphism, Allele, education, Skewed X-inactivation, Gene, 0604 Genetics, Calcium-Binding Proteins/genetics, Science & Technology, CONSEQUENCES, Calcium-Binding Proteins, Membrane Glycoproteins/genetics, 030104 developmental biology, Cytoplasmic and Nuclear/genetics, PATTERNS, Intracellular Signaling Peptides and Proteins/genetics, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Septins, 030217 neurology & neurosurgery
Abstract

X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females. Skewed X-inactivation is often explained by negative selection of one of the alleles. We demonstrate that imbalanced expression of the paternal and maternal X-chromosomes is common in the general population and that the random nature of the X-inactivation mechanism can be sufficient to explain the imbalance. To this end, we analyzed blood-derived RNA and whole-genome sequencing data from 79 female children and their parents from the Genome of the Netherlands project. We calculated the median ratio of the paternal over total counts at all X-chromosomal heterozygous single-nucleotide variants with coverage ≥10. We identified two individuals where the same X-chromosome was inactivated in all cells. Imbalanced expression of the two X-chromosomes (ratios ≤0.35 or ≥0.65) was observed in nearly 50% of the population. The empirically observed skewing is explained by a theoretical model where X-inactivation takes place in an embryonic stage in which eight cells give rise to the hematopoietic compartment. Genes escaping X-inactivation are expressed from both alleles and therefore demonstrate less skewing than inactivated genes. Using this characteristic, we identified three novel escapee genes (SSR4, REPS2, and SEPT6), but did not find support for many previously reported escapee genes in blood. Our collective data suggest that skewed X-inactivation is common in the general population. This may contribute to manifestation of symptoms in carriers of recessive X-linked disorders. We recommend that X-inactivation results should not be used lightly in the interpretation of X-linked variants.

Published
2019

39. Millimeter-wave photonic components for broadband wireless systems

Author

Stohr, A., Babiel, S., Cannard, P.J., Charbonnier, B., van Dijk, F., Fedderwitz, S., Moodie, D., Pavlovic, L., Ponnampalam, L., Renaud, C.C., Rogers, D., Rymanov, V., Seeds, A., Steffan, A.G., Umbach, A., and Weiss, M.

Subjects
Broadband transmission -- Analysis, Microwaves -- Analysis, Photonics -- Research, Semiconductor lasers -- Design and construction, Mobile communication systems -- Analysis, Wireless communication systems -- Analysis, Broadband Internet, Wireless technology, Business, Computers, Electronics, Electronics and electrical industries
Published
2010

42. Inhalable textile microplastic fibers impair lung repair

Author

van Dijk, F., primary, Song, S., additional, van Eck, G.W.A, additional, Wu, X., additional, Bos, I.S.T., additional, Boom, D.H.A., additional, Kooter, I.M., additional, Spierings, D.C.J., additional, Wardenaar, R., additional, Cole, M., additional, Salvati, A., additional, Gosens, R., additional, and Melgert, B.N., additional

Published
2021
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44. Perceptions of the independence of judges: Congruence of society and judiciary

Author

van Dijk, F. and Burgerlijk Recht I

Subjects
judicial independence, Social Sciences(all), European judiciary, Perceptions independence, public trust, Lay judges
Abstract

This open access book is about the perception of the independence of the judiciary in Europe. Do citizens and judges see its independence in the same way? Do judges feel that their independence is respected by the users of the courts, by the leadership of the courts and by politicians? Does the population trust the judiciary more than other public institutions, or less? How does independence of the judiciary work at the national level and at the level of the European Union? These interrelated questions are particularly relevant in times when the independence of the judiciary is under political pressure in several countries in the European Union, giving way to illiberal democracy. Revealing surveys among judges, lay judges and lawyers - in addition to regular surveys of the European Commission - provide a wealth of information to answer these questions. While the answers will not please everyone, they are of interest to a wide audience, in particular court leaders, judges, lawyers, politicians and civil servants.

Published
2020

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