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Among the hematopoietic neoplasms, leukemias are caused by myeloid or lymphoid cells in the bone marrow, which can either be acute with an unfavorable prognosis and mostly affect cats that tested positive for feline viral leukemia (FeLV) or chronic in older cats that have a poor prognosis. Leukemias have several classifications in which the differentiation depends on complementary tests, such as blood profile, myelogram, cytology. and flow cytometry, which help determine the best treatment for the animal. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cancer (CA) is nowadays seen as one of the greatest challenges of medical science, in addition to being considered a public health problem in Brazil, based on the high prevalence of CA of breast in Brazilian women and the high surgical index as a form of treatment. The objective of the present study is to identify the prevalence of breast CA in addition to the types of surgeries performed in women attended in the Santa Casa-Cuiaba / MT oncology sector in 2011. This is an observational and descriptive study With the aim of quantifying the prevalent types of breast cancer in patients who underwent treatment at Santa Casa da Misericórdia in Cuiaba-MT. The study included 47 patients with CA of breast, mean age of 52.04 + 16.94 years. Through the data collected from the medical records of the patients who went through the cancer care sector in 2011, it was possible to identify that the Ductal Infiltrante / Invasive type of CA was the most prevalent among the women in the sample (89.3%), as well as the Quadrantectomy and Lymphododectomy were the main surgery performed in 42.5% of the patients. The Total Mastectomy, the most aggressive of all surgical procedures was performed in 14.8%. It was concluded that the CA of the Ductal Infiltrator / Invasive Ductal type is more prevalent among the women treated in the oncology sector of the Santa Casa de Cuiaba, in addition, the Quadrantectomy associated with chemotherapy and Lymphododectomy was the most prevalent surgery. [ABSTRACT FROM AUTHOR]

Introducción: el cáncer representa una de las principales causas de muerte en niños, niñas y adolescentes a nivel global, el cual es superado escasamente por los accidentes. Las neoplasias más frecuentes son, en primer lugar, las leucemias; segundo, los tumores del Sistema Nervioso Central; y, tercero, los linfomas. Es importante destacar que no existe prevención, sin embargo, hay signos de alarma que si se logran identificar a tiempo pueden verse traducidos en una enfermedad más manejable con una sobrevida más alta y un mejor pronóstico. Objetivo: realizar una actualización académica sobre la importancia de los signos y síntomas de alarma del cáncer infantil. Método: se realizó una investigación documental y se utilizó como buscador de información científica Google Académico. Se evaluaron artículos de investigación y revisión de diferentes bases de datos, como: site de la Organización Mundial de la Salud, site de la Oficina Panamericana de la Salud, Revista de Pediatría Integral, American Cáncer Society y publicaciones periodísticas locales, entre otros. Conclusiones: el cáncer en la infancia y adolescencia no puede prevenirse; sin embargo, si los médicos de los distintos niveles de atención en salud pueden reconocer los signos de alarma ante un probable caso de malignidad, se lograrán referimientos oportunos, diagnósticos tempranos y una mejor tasa de curabilidad y sobrevida en los niños.

Background: Glomus tumors (TG), also known as glomangiomas, originate from the glomus bodies (GC) of the dermis, and are usually benign. As clinical signs are not always obvious, diagnostic imaging is very useful in planning treatment, and surgical excision is the procedure of choice, offering a complete cure to patients with TG. Aim: To report a case of TG on the back of the hand treated in our Hospital. Method: This is a case report of a patient treated at the Orthopedics and Traumatology Service of the Hospital Universitário São Francisco na Providência de Deus - HUSF, located in the city of Bragança Paulista - SP, Brazil. Case Report: The case in this study involved a male patient, 32 years old, with intense pain in the dorsal region of his right hand when touched for two years. Initial clinical examinations revealed no visible abnormalities, but a magnetic resonance imaging (MRI) identified an arthrosynovial cyst between the hamate and the base of the fourth metacarpal. After resection of the cyst, pathological analysis confirmed the diagnosis of GT. Conclusion: An accurate differential diagnosis is crucial for the management of GT, as they can be easily confused with other conditions, leading to inappropriate treatments. The use of specific exams, such as ultrasound and MRI, plays a fundamental role in the correct identification of these tumors, allowing an appropriate therapeutic approach, which often involves surgical resection. Therefore, the importance of a judicious clinical approach and the search for accurate diagnoses is emphasized to ensure effective treatment of patients affected by GT. [ABSTRACT FROM AUTHOR]

Copyright of Dilemas Contemporáneos: Educación, Política y Valores is the property of Dilemas Contemporaneos: Educacion, Politica y Valores and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objetivo: Este estudio evaluó el efecto de la proximidad a fuentes industriales de contaminación del aire sobre la aparición de conglomerados de casos de cáncer infantil en el Área Metropolitana del Valle de Aburrá, del departamento de Antioquia, durante el período 2000-2015. Metodología: La información de casos de cáncer infantil en menores de 15 años residentes del área metropolitana se obtuvo del Registro Poblacional de Cáncer de Antioquia, de dicho periodo. Se identificaron 32 conglomerados industriales, a partir del inventario de la autoridad ambiental local. Se realizaron pruebas de escaneo circular de Kulldorf locales y focalizadas, para detectar conglomerados de cáncer infantil en los municipios y alrededor de los conglomerados industriales respectivamente. Se usó un modelo de regresión multivariable ajustado por estrato socioeconómico, para evaluar el efecto de las variables espaciales. Resultados: La tasa de incidencia específica en el Valle de Aburrá para el periodo evaluado fue de 117,13 casos por millón de niños menores de 15 años. Las tasas de incidencia más altas se presentaron en los municipios de Medellín y Sabaneta. La prueba de Kulldorf identificó 12 conglomerados espaciales y 8 espaciotemporales con significación estadística en 7 de los municipios, particularmente en Bello y Medellín. Las pruebas focalizadas identificaron conglomerados alrededor de 20 conglomerados industriales. En los modelos multivariables, un conglomerado en Bello evidenció asociación estadísticamente significativa e inversa entre la incidencia y la distancia al conglomerado con direccionalidad sureste. Conclusión: Algunos conglomerados espacio-temporales de cáncer infantil en el Área Metropolitana del Valle de Aburrá entre 2000 y 2015 están relacionados con proximidad a fuentes industriales de contaminación del aire.

Este artigo apresenta uma análise da obra Sur la Nature et la Guerison des Cancers (1701), do médico francês Claude Gendron, publicada em Paris. O ponto de atenção deposita-se em sua análise sobre a gênese tumoral, que se distancia parcialmente do humoralismo, que era pautado na interrupção do fluxo humoral para adotar uma perspectiva mais local, segundo a qual os tumores eram decorrentes da transformação de estruturas locais e da composição de massas duras fruto das suas perdas de função. Como procuramos demonstrar, a passagem de uma abordagem mais sistêmica para local, contudo, não acompanhou um abandono de categorias humoralistas, como apontado por trabalhos em história da medicina. As fontes consultadas foram tratados de medicina franceses e espanhóis entre 1690 e 1720, cotejados com bibliografia na temática.

A presente revisão tem por objetivo copilar informações já relatadas sobre a fibropapilomatose em tartarugas marinhas, doença altamente debilitante e potencialmente fatal, caracterizada pela formação de fibropapilomas cutâneos e fibromas viscerais, possuindo distribuição mundial, afetando principalmente tartarugas verdes. A etiologia dessa enfermidade ainda não foi estabelecida, mas a suspeita é de uma infecção viral que pode ocorrer associada a fatores ambientais. O número e tamanhos dos tumores variam entre cada indivíduo e a sua presença, em alguns casos dificulta a qualidade de vida desse animal. A confirmação ocorre por meio de diagnóstico histológico. A principal terapia empregada é a remoção cirúrgica dos papilomas.

Introducción: Los tumores pardos ocasionados por hiperparatiroidismo, ya sea primario o secundario, son lesiones de tejido blando intraóseo vascularizado, que se presentan con mayor frecuencia en huesos largos; ocasionalmente, las lesiones llegan a ser periféricas y se localizan sobre procesos alveolares de maxilar y mandíbula. Objetivo: Presentar un paciente bajo tratamiento de hemodiálisis, que presenta tumores pardos en región maxilofacial, en relación con hiperparatiroidismo secundario. Caso clínico: Paciente de 39 años, con antecedentes de insuficiencia renal crónica, diagnosticada hace más de 20 años e hiperparatiroidismo secundario, para lo cual lleva tratamiento con régimen regular de diálisis. Acude por presentar deformidad facial; radiológicamente presenta lesiones osteolíticas en maxilar y mandíbula con impresión diagnóstica de tumores pardos. Conclusiones: Esta manifestación de hiperparatiroidismo secundario se observa al incrementarse la longevidad de los pacientes con fallo renal. Una completa evaluación del paciente puede ayudar a un correcto diagnóstico.

Uma revolução no entendimento da gênese do câncer humano vem acontecendo, e sua natureza fundamentalmente genética foi reconhecida. Os cânceres gastrointestinais apresentam alta incidência e prognóstico reservado na maioria dos casos quando da sua apresentação em nosso meio. Espera-se que a biologia molecular traga novos caminhos para o diagnóstico e tratamento mais efetivos. No nosso trabalho, são abordados os aspectos atuais da carcinogênese colorretal, esofágica e gástrica, bem como os genes e seus sub-produtos (proteínas) envolvidos. As implicações clínicas destes novos conhecimentos, como as aplicações no diagnóstico precoce, a existência de marcadores prognósticos e a possibilidade de novos tratamentos, são discutidos.

Objective: This study evaluated the effect of proximity to industrial sources of air pollution on the occurrence of clusters of childhood cancer cases in the Aburrá Valley Metropolitan Area, Department of Antioquia, during the 2000-2015 period. Methodology: The information on childhood cancer cases in children under 15 years of age residing in the metropolitan area was obtained from the Registro Poblacional de Cáncer de Antioquia (Antioquia Cancer Population Registry) for that period. 32 industrial clusters were identified based on the local environmental authority's inventory. Local and targeted Kulldorff's circular scan tests were performed to detect childhood cancer clusters in the municipalities and surrounding the industrial clusters, respectively. We used a multivariate regression model adjusted for socioeconomic strata to assess the effect of spatial variables. Results: The specific incidence rate in the Aburrá Valley for the evaluated period was 117.13 cases per million children under 15 years of age. The highest incidence rates occurred in the municipalities of Medellín and Sabaneta. The Kulldorff test identified 12 spatial clusters and 8 space-time clusters that were statistically significant in 7 municipalities, particularly in Bello and Medellín. The targeted tests identified childhood cancer clusters surrounding 20 industrial clusters. In multivariate models, an industrial cluster in Bello showed a statistically significant inverse association between incidence and distance from the industrial cluster toward the southeast. Conclusion: Some space-time childhood cancer clusters in the Aburrá Valley Metropolitan Area between 2000 and 2015 are related to proximity to industrial sources of air pollution. [ABSTRACT FROM AUTHOR]

Se presenta un tumor carcinoide de lleon terminal, con metástasis múltiples de hígado y ascitis, acompañado de un síndrome carcinoide. Estando internado hace un cuadro oclusivo de intestino delgado, por el cual se opera, comprobando la presencia del tumor y metástasis. Retrospectivamente, al estudiar la histología del tumor, se hace diagnóstico interpretando la rica sintomatología asociada.

Objetivo. Los tumores de la región pineal son infrecuentes, de difícil acceso quirúrgico y limitadas posibilidades de resección debido a su localización en una encrucijada de estruc- turas neurovasculares. Este trabajo tiene como objetivo describir los resultados del proceso de diagnóstico y tratamiento de los pacientes con lesiones de región pineal en el Hospital Hermanos Ameijeiras entre enero de 2016 y enero de 2021. Métodos. Se realizó un estudio observacional, descriptivo y retrospectivo tipo cohorte en dicha institución en una serie de 19 pacientes con diagnóstico de una lesión en la región pineal. Resultados. Predominaron pacientes jóvenes con germinomas y clínica de hipertensión endocraneana. Los marcado- res tumorales fueron positivos 31,6 %. La supervivencia global después de 6 meses fue del 94,7 % (18 pacientes), logrando un buen estatus funcional y control de la enfermedad en los pacientes. Conclusiones. Las lesiones de la región pineal suponen un riesgo elevado para la vida de los pacientes tanto por la lesión como por el proceso de tratamiento. La selección adecuada de la modalidad terapéutica y el refinamiento de los métodos, particularmente la combinación multimodal planificada de éstos, ha constituido la clave para el éxito.

Introduction: Colon cancer diagnosis is usually performed late; so, it is necessary to search for prevention options. In vivo models are an option for the evaluation of chemopreventive agents, which are based mainly on the induction and promotion of carcinogenesis; however, they take a long time. This work aimed to evaluate and propose a carcinogenesis model, with tumor manifestation in a short time to prove the efficacy of chemopreventive compounds. Method: Colon carcinogenesis was induced in three groups (n = 7) male BALB/c mice with azoxymethane (AOM) and dextran sodium sulfate (DSS). The damage was assessed 14 weeks after the induction. Protocols were: 1) P1: two AOM injections and two DSS cycles at 1.5 % for five days, with three resting days between cycles; 2) P2: one AOM injection and two DSS cycles at 2 % for seven days with five rest days, and 3) P3: one AOM injection and two DSS cycles at 2 % for four days, with four resting days. Negative control was used in parallel, P0: with one injection of saline solution and water ad libitum. Weight, disease activity index (DAI), survival, tumor incidence, lipids, and protein oxidation were determined. Results: P2 showed greater severity in the assessed signs (100 % tumor incidence, colon weight/length ratio 101.68 ± 2.99 mg/cm), with low survival (43 %). P1 depicted lower mortality (14 %) and 83 % tumor incidence, without a significant difference to P2. P3 developed the disease but to a lesser degree (33 % tumor incidence). Furthermore, the three protocols showed lipid oxidation (0.4-0.58 ng/μg of protein) and proteins oxidation (0.6-1 ng/μg of protein). The P1 and P3 induction protocols presented less mortality, weight loss, and acceptable DAI, a weight/length ratio higher than the negative control and presence of tumors. Discussion or Conclusion: The use of AOM (10mg/kg) combined with DSS (1.5-2 %) are suitable models to evaluate the carcinogenic effect of compounds of interest, inflammation signs, lipids and proteins oxidation and a survival number adequate to perform the statistical analysis leading to accurate conclusions. Therefore, P1 and P3 are protocols that can be used in chemoprevention assays with satisfactory results. [ABSTRACT FROM AUTHOR]

Introduction: Expansive intraspinal processes usually have an insidious course that makes their early diagnosis difficult. Intra-spinal tumors are classified according to their location in the spinal canal: extradural and intradural, and these are classified as extramedullary and intramedullary. At the beginning, they can cause non-specific pain conditions and, sometimes, root-type pain. The patient may have symptoms such as: loss of strength, loss of balance, loss of sensation, sphincter disorders. Intra-spinal neoplasms, when diagnosed, have an indication for surgical treatment. Material and methods: The clinical case of a 14-year-old male adolescent is described, pain in the lumbar region for four years, of insidious onset, intermittent, progressive, exacerbated six months ago, with radiation to the lower extremities, which is accompanied by progressive paresthesia and paresis predominantly in the lower right limb. Results: Bilateral L4 and L5 laminotomy is performed, exploration and resection of the tumor and release of nerve roots. Tumor with characteristics similar to adipose tissue is obtained, where a wide vascular network is observed inside, with an approximate size of 14 Ã--10 Ã--4 mm, ovoid in shape, flattened with a smooth and shiny surface. Conclusion: Spinal tumors are relatively rare tumors, however, of these tumors, the extradural intraspinal location accounts for half of the cases. In our patient, the diagnosis of lipoma of the filum terminale was integrated, which corresponds to less than 1% of all tumors of the spine. [ABSTRACT FROM AUTHOR]

La localización de los tumores malignos en las paredes toracoabdominales, sean ellos primitivos o secundarios, requieren resecciones muy amplias, que en ocasiones plantean al cirujano problemas de difícil solución...

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Los tumores óseos y de partes blandas localizados en el pie son muy poco frecuentes. El lipoblastoma es una neoplasia benigna de partes blandas rara que se presenta exclusivamenteen la población pediátrica, con predilección por el sexo masculino. Su asiento preferente es en las extremidades pero raramente afecta el pie.Presentamos un caso de lipoblastomade pie de un niño de 13 meses de edad y realizamos una revisión de la literatura.

Sesión del 23 de Mayo de 1934.

Sesión del 28 de Noviembre de 1934. En colaboración con el anatómico-patológica del doctor P. Larguero Ibarz

The aim of this study was to determine the prevalence of cutaneous neoplasms in horses treated at the Center for the Development of Livestock at the Federal University of Bahia, as well as to correlate it with the coat color, breed, and age of the animal. For that, the attendance records for the last ten years were reviewed. When evaluating the files, 13 cases of cutaneous tumor in horses confirmed by histopathology and cytology were observed. The most prevalent skin tumors were sarcoid (38.5%), melanoma (23%), and fibrosarcoma (15.4%). Regarding the equine coat color, gray and sorrel horses were the most frequent with 30.7% and 23.1% of cases, respectively. As for the equine breed, the mangalarga marchador was the most prevalent (38.4%). Regarding age, 38.46% of the horses were up to 5 years old, 30.77% of the animals were between 4 and 10 years old, and 30.76% were between 11 and 16 years old. In the end, it can be concluded that sarcoid and melanoma were the most prevalent neoplasms. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Gastroenterología del Perú is the property of Sociedad de Gastroenterologia del Peru and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The cutaneous adnexal neoplasms represent a wide group of tumors that differentiate morphologically into one or more of the skin's adnexal structures, being that the follicular, sebaceous or apocrine/eccrine epithelium. They can affect both adults and children. OBJECTIVE: To describe the histopathologic features of cutaneous adnexal neoplasms in pediatric population. MATERIALS AND METHODS: Descriptive and retrospective study that included all cases of cutaneous adnexal neoplasms diagnosed in children in a 20-year period. Epidemiologic, clinical and histopathological characteristics were recorded. RESULTS: A total of 84 cases were included; the female gender was the most affected (n = 51), the median of age at the moment of diagnosis was 15 years, the upper extremities were the most frequent topographic site (n = 25) and the median time of evolution of the lesions was of 12 months. The most frequent adnexal tumor was the pilomatrixoma (n = 59), being the follicular tumors the most frequent type of differentiation, followed by the apocrine/eccrine type. All of the analyzed tumors were benign and 50 cases had a positive clinical-pathologic correlation. CONCLUSIONS: The pilomatrixoma is the most frequent adnexal neoplasm in children, which means that follicular differentiation is the most prevalent type. There is satisfactory clinical-pathologic diagnostic correlation in follicular tumors, but not in the rest of the categories, meaning that histopathology remains the gold standard for the identification of these lesions. [ABSTRACT FROM AUTHOR]