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Practical Application The aim of this study was to investigate the effect of different ultrasound treatment (UT) conditions (Control, UT‐150, UT‐300, UT‐450, Vacuum‐UT‐150, Vacuum‐UT‐300, Vacuum‐UT‐450) on the brining kinetics and meat quality of chicken breast. The results showed that vacuum‐ultrasonic‐assisted treatment greatly accelerated the transfer of moisture and NaCl, and the highest yield was obtained by ultrasonic power of 450 W. The mass transfer kinetics (k1 and k2) were significantly related to vacuum pretreatment and ultrasonic power. The values of k1 for total and moisture weight changes decreased with the increase of ultrasonic power, whereas the values of k2 increased with vacuum pretreatment. The application of ultrasound treatment with vacuum improved the NaCl effective diffusion coefficients (De) from 1.189 × 10−9 to 1.308–1.449 × 10−9 m2/s, and the highest De was found with Vacuum‐UT‐450. The treatment of ultrasound and vacuum can reduce shear force and enhance the water‐holding capacity (WHC). According to the analysis of water distribution, vacuum and ultrasound could decrease the T23 values, indicating that the mobility of water decreased. The result of microscopic observation further supported that the disruption of myofibrils was related to the tenderness and WHC changes, which was caused by vacuum and ultrasound treatment. Thus, Vacuum‐UT brining could be employed as an emerging technology for improving the efficiency of brining and meat quality of other meat.Vacuum‐ultrasonic‐assisted static brine is an effective and feasible treatment to replace tumbling treatment for maintaining the integrity of the muscle bundles and accelerating the brining rate. [ABSTRACT FROM AUTHOR]

Background: Inverted nipple deformity presents an unsatisfactory appearance that may induce an unpleasant sex life, but can also be associated with psychological discomfort and increased the functional problems, such as local irritation and inflammation. Methods: Multiple techniques have been used to correct inverted nipples, but they mostly lead to different problems such as deficiency of the nerve or duct, recurrence of the inverted nipple, and hypopigmented scars in the areola. To minimize complications and maintain the stability of the reconstructed nipple, we presented a minimal incision technique that designed four 3-mm-sized horizontal microincisions, which ran a sun-cross through the periphery and the core of the nipple to push the nipple together, then a vertical suture ran longitudinal to close the transverse incision to stabilize the projection. Results: This technique was performed in 71 patients classified as grade II or III of the inverted nipples, comprising 53 congenital cases and 18 patients with acquired deformity. Thirty-four patients had bilateral inverted nipples, and 37 patients had unilateral inverted nipple. During a mean follow-up period of 15 months, 70 corrected nipples remained raised without recurrence, and one nipple was found retracted at the outpatient clinic after 3 months. There were no serious complications associated with surgery regarding nipple necrosis, seven patients got temporary swelling, two patients got infected after touching water, three patients got extravasated blood, eight patients indicated that they touched scar under the nipple, and two patients reflected nipple dysesthesia. In the 15 months follow-up, the patients with Grade II nipple inversion maintained a nipple average height of 9.54 ± 0.95, and the patients with Grade III nipple inversion maintained a nipple average height of 9.19 ± 1.09, and 86.63% of patients were satisfied with their results. Conclusion: This is a simple, safe, effective and reliable technique that should be considered, providing sustained results over the long-term follow-up period with a high rate of stable eversion and low incidence of ischemia, necrosis, scarring and dysesthesia. The vertical scar of the transverse incision closure leads to an esthetic appearance without apparent scarring and minimizes the risk of an altered nipple sensation. Level of Evidence IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

Background: Fractures at the distal end of the radius, a prevalent orthopedic concern, challenge clinicians due to their complex nature and the diverse patient demographics they affect. Primary stability is key, especially in cases involving osteoporotic bones or younger patients. The Ellis plate with a locking screw mechanism offers a promising solution to achieve this stability, potentially preventing secondary displacement regardless of bone quality. Aims and Objectives: This study aims to rigorously assess the effectiveness of the Ellis volar locking compression plate in treating distal end radius fractures. It focuses on evaluating functional outcomes post-treatment, providing insights into the efficacy of this approach. Materials and Methods: This study evaluated the efficacy of the Ellis plate in managing distal radius fractures, under ethical approval number KMC/IEC/Ortho/2021-5. Twenty adult patients with unstable fractures were included based on specific criteria and provided informed consent. Exclusion criteria included unwillingness for surgery, medical unsuitability, osteoporosis, minors, and compound fractures with vascular injury. Surgical outcomes were assessed using the Gartland and Werley scoring system, with follow-up appointments scheduled over 1 year to monitor progress and adherence to physiotherapy plans. Results: The study encompassed 20 patients, with a gender distribution of 12 males and eight females and an average age of 43.3 years. Utilizing the Gartland and Werley demerit grading system, the study reported 45% superb outcomes, another 45% good outcomes, 10% fair outcomes, and no poor outcomes. This distribution highlights the potential of the Ellis plate technique in achieving positive results in fracture treatment. Conclusion: The study concludes that the Ellis plate technique is a viable and effective option for stabilizing distal end radius fractures. However, achieving the best possible outcomes depends on several factors, including strict adherence to AO principles, maintaining high standards of aseptic practice, following appropriate post-operative rehabilitation protocols, and ensuring comprehensive patient education. This multifaceted approach is crucial for the successful treatment of these fractures.

The frequency of severe postpartum haemorrhage did not differ between cephalad-caudad and transverse blunt expansion hysterotomy. Transverse blunt expansion hysterotomy may be associated with additional sutures after repair of the hysterotomy.. • Caesarean section is a common method of delivery worldwide, accounting for up to 45% of births in some countries. • Caesarean section remains a major cause of maternal morbidity, particularly postpartum haemorrhage (PPH). • The incidence of PPH is higher for caesarean section than vaginal delivery, ranging from 3% to 15%. • As far as the surgical technique is concerned, French guidelines recommend performing blunt expansion of the low transverse hysterotomy with fingers rather than scissors to reduce bleeding. • The preferences for transverse or cephalad-caudal blunt expansion hysterotomy of the low transverse uterine incision during caesarean section differs between countries. The global prevalence of caesarean section as a delivery method is increasing worldwide. However, there is notable divergence among countries in their national guidelines regarding the optimal technique for blunt expansion hysterotomy of the low transverse uterine incision during caesarean section (cephalad-caudad or transverse). To compare the risk of severe postpartum haemorrhage (PPH) between cephalad-caudad and transverse blunt expansion hysterotomy during caesarean section. This prospective comparative observational study was conducted in a university maternity hospital. All women who gave birth to one infant by caesarean section after 30 weeks of gestation between November 2020 and November 2021 were included in this study. The exclusion criteria were a coagulation disorder, the presence of placenta previa, multiple pregnancies, or enlargement of the hysterotomy with scissors. The choice between cephalad-caudad or transverse blunt expansion of the low transverse hysterotomy was left to the surgeon's discretion. The primary outcome measure was severe PPH, defined as estimated blood loss ≥ 1000 ml. Univariate and multivariate analyses were employed to assess the risk of severe PPH associated with the two methods of enlarging the low transverse hysterotomy. The study included 850 women, of whom 404 underwent transverse blunt expansion and 446 underwent cephalad-caudad blunt expansion. The overall incidence of severe PPH was 13.3 %. Univariate analysis revealed no significant difference in the frequency of severe PPH between the cephalad-caudad and transverse blunt expansion groups (13.9 % vs 12.6 %; p = 0.61). However, the use of additional surgical sutures (mainly additional haemostatic stitches) was less common with cephalad-caudad blunt expansion (26.7 % vs 36.9 %; p < 0.05). Multivariate analysis showed no significant difference in risk between the two techniques (odds ratio 1.17, 95 % confidence interval 0.77–1.78). No significant difference in the risk of severe PPH was found between cephalad-caudad and transverse blunt expansion of the low transverse hysterotomy during caesarean section. [ABSTRACT FROM AUTHOR]

Introduction: Metacarpal fractures account for 25%-50% of all hand fractures and may negatively impact hand function and ability to work. Percutaneous transverse pinning of non-articular metacarpal fractures allows mobilisation immediately after the procedure. Methods: Between March 2017 and February 2022, 56 patients undergoing percutaneous transverse pinning for unstable metacarpal fractures were prospectively recruited. We investigated surgical outcomes in terms of Patient-rated Wrist/Hand Evaluation (PRWHE) and pre-and post-operative radiographic evaluation. The Student t-test was used to compare the means of PRWHE values after surgery. Statistical significance was set at p < 0.05. Results: The mean age was 40.21 ± 17.9 years (range of 16 to 86 years). The average operating time was 27.96 min. The mean follow-up period was 14.3 ± 6.4 months (from 2 to 41 months). The mean PRWHE score was 6.5 ± 1.8. None of the patients had clinically observable rotational deformities, and the functional outcomes were satisfactory. Conclusion: Percutaneous transverse pinning for non-articular metacarpal fractures restores excellent function, and imaging results are satisfactory. Further high-quality clinical trials are required to validate these results on a larger scale. Level of evidence: II, prospective cohort study. [ABSTRACT FROM AUTHOR]

challenge clinicians due to their complex nature and the diverse patient demographics they affect. Primary stability is key, especially in cases involving osteoporotic bones or younger patients. The Ellis plate with a locking screw mechanism offers a promising solution to achieve this stability, potentially preventing secondary displacement regardless of bone quality. Aims and Objectives: This study aims to rigorously assess the effectiveness of the Ellis volar locking compression plate in treating distal end radius fractures. It focuses on evaluating functional outcomes post-treatment, providing insights into the efficacy of this approach. Materials and Methods: This study evaluated the efficacy of the Ellis plate in managing distal radius fractures, under ethical approval number KMC/IEC/Ortho/2021-5. Twenty adult patients with unstable fractures were included based on specific criteria and provided informed consent. Exclusion criteria included unwillingness for surgery, medical unsuitability, osteoporosis, minors, and compound fractures with vascular injury. Surgical outcomes were assessed using the Gartland and Werley scoring system, with follow-up appointments scheduled over 1 year to monitor progress and adherence to physiotherapy plans. Results: The study encompassed 20 patients, with a gender distribution of 12 males and eight females and an average age of 43.3 years. Utilizing the Gartland and Werley demerit grading system, the study reported 45% superb outcomes, another 45% good outcomes, 10% fair outcomes, and no poor outcomes. This distribution highlights the potential of the Ellis plate technique in achieving positive results in fracture treatment. Conclusion: The study concludes that the Ellis plate technique is a viable and effective option for stabilizing distal end radius fractures. However, achieving the best possible outcomes depends on several factors, including strict adherence to AO principles, maintaining high standards of aseptic practice, following appropriate post-operative rehabilitation protocols, and ensuring comprehensive patient education. This multifaceted approach is crucial for the successful treatment of these fractures. [ABSTRACT FROM AUTHOR]

Objective: To analyze the rates of complications after pediatric temporal bone fractures (TBF) and the utility of the longitudinal, transverse, and mixed versus the otic capsule sparing (OCS) and otic capsule violating (OCV) classification systems in predicting these complications. Data Sources: PubMed, Scopus, and CINAHL. Review Methods: Per PRISMA guidelines, studies of children with TBFs were included. Meta‐analyses of proportions were performed. Results: A total of 22 studies with 1376 TBFs were included. Children with TBF had higher rates of conductive hearing loss (CHL) than sensorineural hearing loss (SNHL) (31.3% [95% confidence interval [CI] 23.2‐40.1] vs 12.9% [95% CI 8.9‐17.5]). No differences in both CHL and SNHL were seen between longitudinal and transverse TBFs; however, OCV TBFs had higher rates of SNHL than OCS TBFs (59.3% [95% CI 27.8‐87.0] vs 4.9% [95% CI 1.5‐10.1]). Of all patients, 9.9% [95% CI 7.2‐13.1] experienced facial nerve (FN) paresis/paralysis, and 13.4% [95% CI 5.9‐23.2] experienced cerebrospinal fluid otorrhea. Transverse TBFs had higher rates of FN paresis/paralysis than longitudinal (27.7% [95% CI 17.4‐40.0] vs 8.6% [95% CI 5.2‐12.8]), but rates were similar between OCS and OCV TBFs. Conclusion: CHL was the most common complication after TBF in children; however, neither classification system was superior in identifying CHL. The traditional system was more effective at identifying FN injuries, and the new system was more robust at identifying SNHL. While these results suggest that both classification systems might have utility in evaluating pediatric TBFs, these analyses were limited by sample size. Future research on outcomes of pediatric TBFs stratified by type of fracture, mainly focusing on long‐term outcomes, is needed. [ABSTRACT FROM AUTHOR]

Buried pipelines are susceptible to non-uniform excitations in different directions, which may lead to severe damage. This study investigates the pipeline performance under longitudinal and transverse non-uniform excitations via multi-point shaking table tests. The results demonstrated that the seismic response of pipeline was affected more by soil inconsistent motion under transverse non-uniform excitations, while it was affected more by the degree of pipeline–soil interaction in longitudinal direction. The pipeline maximum peak bending strains were larger than the maximum peak axial strains at higher loading intensity. These indicated that the pipeline response mechanisms are different under longitudinal and transverse non-uniform excitations. [ABSTRACT FROM AUTHOR]

Background Polymethylmethacrylate (PMMA) is the most often used polymer for denture bases because to its inexpensive cost, lightweight nature, insolubility in mouth fluid, outstanding cosmetic features, and ease of repairability. However, various limitations such as insufficient surface hardness, low strength, brittleness, weak flexural strength, poor impact strength, and low fatigue resistance have a detrimental impact on acrylic resins. Method This research examined the impact strength, transverse strength, surface hardness, surface roughness, and color stability of heat-cured acrylic denture base material after 0.5% and 1% by wt. CNFs were added. The cellulose nanofibers were combined with a PMMA monomer for 5 minutes in a probe sonicator. One group of samples was made without cellulose nanofibers in PMMA, while two groups were prepared with 0.5% and 1% CNFs by weight, and tests of the impact strength, transverse strength, surface hardness, surface roughness, and color stability of the samples were carried out. The data were analyzed using descriptive statistics, including the mean and standard deviation, and bar charts were used to visualize the results. Sample interactions and fiber dispersion were assessed using FTIR and FE-SEM. Results Compared to the control group, 0.5% by wt. and 1% by wt. CNF improved the impact and transverse strength substantially, while shore D surface hardness was not improved. Hue (a) and chroma (b) were substantially influenced by CNF at 0.5% by weight compared to the control group, although surface roughness and color value (L) were not. Surface roughness, color value (L), and color hue (a) were substantially impacted by 1% compared to the control group; however, color chroma (b) was not. Conclusions This research found that 0.5% and 1% by wt. CNF in PMMA resin increased the impact strength, transverse strength, surface hardness, surface roughness, color value, hue, and chroma of heat-cured polymethyl methacrylate denture base material.

Purpose: We aim to verify predictions showing T2 relaxation rate of nanoparticle clusters and its dependence on spacing, size, geometry, and pulse sequence. Methods: We performed a laboratory validation study using nanopatterned arrays of iron oxide nanoparticles to precisely control cluster geometry and image diverse samples using a 4.7T MRI scanner with a T2‐weighted fast spin‐echo multislice sequence. We applied denoising and normalization to regions of interest and estimated relative R2 for each relevant nanoparticle array or nanocluster array. We determined significance using an unpaired two‐tailed t‐test or one‐way analysis of variance and performed curve fitting. Results: We measured a density‐dependent T2 effect (p = 8.9976 × 10−20, one‐way analysis of variance) and insignificant effect of cluster anisotropy (p = 0.5924, unpaired t‐test) on T2 relaxation. We found negative quadratic relationships (−0.0045[log τD]2–0.0655[log τD]−2.7800) for single nanoparticles of varying sizes and for clusters (−0.0045[log τD]2–0.0827[log τD]−2.3249) for diffusional correlation time τD = rp2/D. Clusters show positive quadratic relationships for large (3.8615 × 10−6 [dpp/rp]2–9.3853 × 10−5 [dpp/rp]−2.0393) and exponential relationships for small (−2.0050[dpp/rp]0.0010) clusters. Calculated R2 peak values also align well with in silico predictions (7.85 × 10−4 ms compared with 1.47 × 10−4, 4.23 × 10−4, and 5.02 × 10−4 ms for single iron oxide nanoparticles, 7.88 × 10−4 ms compared with 5.24 × 10−4 ms for nanoparticle clusters). Conclusion: Our verification affirms longstanding in silico predictions and demonstrates aggregation‐dependent behavior in agreement with previous Monte Carlo simulation studies. [ABSTRACT FROM AUTHOR]

The paper discusses numerical implementations of various inversion schemes for generalized V-line transforms on vector fields introduced in [G. Ambartsoumian, M. J. Latifi, and R. K. Mishra, Inverse Problems, 36 (2020), 104002]. It demonstrates the possibility of efficient recovery of an unknown vector field from five different types of data sets, with and without noise. We examine the performance of the proposed algorithms in a variety of setups, and illustrate our results with numerical simulations on different phantoms. [ABSTRACT FROM AUTHOR]

Understanding of tongue deformations during mammalian mastication is limited, but has benefited from recent developments in multiplanar imaging technology. Here, we demonstrate how a standardized radiopaque marker implant configuration and biplanar fluoroscopy can quantify three-dimensional shape changes during chewing in pigs. Transverse and sagittal components of the three-dimensional angle between markers enable characterizing deformations in anatomically relevant directions. The transverse component illustrates bending to the left or to the right, which can occur symmetrically or asymmetrically, the latter sometimes indicating regional widening. The sagittal component reflects 'arching' or convex deformations in the dorsoventral dimension symmetrically or asymmetrically, the latter characteristic of twisting. Trends are detected in both the transverse and sagittal planes, and combinations thereof, to modify tongue shape in complex deformations. Both the transverse and sagittal components were also measured at key jaw and tongue positions, demonstrating variability particularly with respect to maximum and minimum gape. This highlights the fact that unlike tongue position, tongue deformations are more independent of jaw position, likely in response to the ever-changing bolus shape and position. From a methodological perspective, our study showcases advantages of a repeatable three-marker implant configuration suitable for animals of different sizes and highlights considerations for different implant patterns. This article is part of the theme issue 'Food processing and nutritional assimilation in animals'. [ABSTRACT FROM AUTHOR]

In this present study, we are interested in the use of a precise theory of shear deformation for the buckling analysis of plates with functional gradation simply supported such as the refined theory of plates with four variables. Several parameters of comparison have been used, dimensional and nondimensional. The displacement field is compatible with this study, the nonuse of shear correction factors is satisfied, and the choice of material is very precise in such a way are variable according to the thickness of the plate and on the other hand to make comparison with other researcher and confirms that this study gives precise results and converges. The transverse shear stresses vary through the thickness, the results found is also studied and discussed. [ABSTRACT FROM AUTHOR]

Background: The colon has two different embryological origins, which is why it can be divided into right and left with different characteristics each one; therefore, neoplastic lesions have a different clinical picture and are also associated with different pathologies. Objective: To describe the clinical and histopathological characteristics of malignant colon tumors acording to their location. Material and methods: Descriptive, retrospective study with 94 patients diagnosed with colon cancer. Descriptive statistics were performed with the calculation of frequencies and percentages, and chi-squared tests were calculated. Results: Mean age was 61.3 years, 49 (52.1%) were women; 53 (56.4%) were left-sided and 41 (43.6%) right-sided. The main symptom was hematochezia in 32 (60.4%), in patients with left cancer; and diarrhea in 20 (48.8%), in patients with right-sided colon cancer. The presentation of stage I tumors and polyps, p = 0.044 and p = 0.043, respectively, was more frequent on the right side compared to the left side; in the left, hematochezia (p = 0.001), narrow stools (p = 0.05), and a history of type 2 diabetes mellitus (T2DM) (p = 0.036) were more frequent compared to the opposite site. Conclusions: Stage I and the presence of polyps were more frequent in right-sided cancer compared to left-sided cancer; T2DM, as well as hematochezia and narrow stools were more associated with the left side compared to the right side. [ABSTRACT FROM AUTHOR]

Background and purpose: Longitudinally extensive transverse myelitis (LETM) associated with aquaporin‐4 autoantibodies (AQP4‐IgG) can cause severe disability. Early diagnosis and prompt treatment are critical to prevent relapses. A novel score is described based on clinical and neuroimaging characteristics that predicts AQP4‐IgG positivity in patients with LETM. Methods: Patients were enrolled both retrospectively and prospectively from multiple Italian centers. Clinical and neuroimaging characteristics of AQP4‐IgG positive and negative patients were compared through univariate and multivariate analysis. Results: Sixty‐six patients were included. Twenty‐seven (41%) were AQP4‐IgG positive and median age at onset was 45.5 years (range 19–81, interquartile range 24). Female sex (odds ratio [OR] 17.9, 95% confidence interval [CI] 2.6–381.9; p = 0.014), tonic spasms (OR 45.6, 95% CI 3.1–2197; p = 0.017) and lesion hypointensity on T1‐weighted images (OR 52.9, 95% CI 6.8–1375; p = 0.002) were independently associated with AQP4‐IgG positivity. The AQP4‐IgG positivity in myelitis (AIM) score predicted AQP4‐IgG positivity with 85% sensitivity and 95% specificity. Positive and negative likelihood ratios were 16.6 and 0.2 respectively. The inter‐rater and intra‐rater agreement in the score application were both excellent. Conclusions: The AIM score predicts AQP4‐IgG positivity with good sensitivity and specificity in patients with a first episode of LETM. The score may assist clinicians in early diagnosis and treatment of AQP4‐IgG positive LETM. [ABSTRACT FROM AUTHOR]

Twin tungsten electrode – wire electrode indirect arc welding (TTW IAW) was a novel welding method. In this paper, the wettability and spreading of weld bead of TTW IAW were investigated by comparing with single tungsten electrode – wire electrode indirect arc welding (STW IAW). Results showed that compared to STW IAW, TTW IAW possessed larger arc width and greater arc heat distribution range with smaller variation gradient, due to the lower velocity of charged particles toward the arc center, caused by the smaller electromagnetic force acting on the arc plasma. So did the temperature distribution of weld pool of TTW IAW. Moreover, the process stability of TTW IAW was better. Besides, at the molten pool front, the transverse convection of the melted metal of TTW IAW was adequate, because of the superior wettability and long flow duration of the melted metal; at the molten pool rear, the inward convection of the melted metal of TTW IAW was weak mainly owing to the low Marangoni force. Therefore, the weld bead width of TTW IAW increased by about 25.0% and the wetting angle of the weld bead decreased by about 25.7% compared to STW IAW, which indicated that the weld bead spreading of TTW IAW was better. [ABSTRACT FROM AUTHOR]

RationaleThe evidence for outpatient pulmonary embolism (PE) management apart from hospitalization is expanding. The availability and ease of direct oral anticoagulants have facilitated this transition. The literature, however, is sparse on the topic of comprehensive management of pulmonary embolism in the primary care clinic setting. As such, the role of the primary care physician in the complete diagnosis, risk stratification for outpatient eligibility, and initiation of treatment is unclear.Case presentationsCase 1: A 33-year-old man with known heterozygous Factor V Leiden mutation and a remote history of deep vein thrombosis presented to his primary care physician's office with 2 days of mild pleuritic chest pain and a dry cough after a recent transcontinental flight. Case 2: A 48-year-old man with a complex medical history including recent transverse myelitis presented to his primary care family physician with dyspnea and pleuritic chest pain for 6 days.DiagnosisCase 1: Computed tomographic pulmonary angiography that same afternoon showed multiple bilateral segmental and subsegmental emboli as well as several small pulmonary infarcts. Case 2: The patient's D-dimer was elevated at 1148 ng/mL. His physician ordered a computed tomographic pulmonary angiography, performed that evening, which showed segmental and subsegmental PE.InterventionsBoth patients were contacted by their respective physicians shortly after their diagnoses and, in shared decision-making, opted for treatment at home with 5 days of enoxaparin followed by dabigatran.OutcomesNeither patient developed recurrence nor complications in the subsequent 3 months.LessonsThese cases, stratified as low risk using the American College of Chest Physicians criteria and the PE Severity Index, are among the first in the literature to illustrate comprehensive primary care-based outpatient PE management. Care was provided within an integrated delivery system with ready, timely access to laboratory, advanced radiology, and allied health services. This report sets the stage for investigating the public health implications of comprehensive primary care-based PE management, including cost-savings as well as enhanced patient follow-up and patient satisfaction.

Objectives: Currently available reports on mandibular transverse growth are limited to two-dimensional images and cross-sectional studies. The objective of this study was to examine transverse growth of the mandibular body in untreated growing individuals during the mixed dentition stage using longitudinal three-dimensional imaging. Methods: CBCT images of 25 (13 females and 12 males) untreated subjects at two time points were analyzed. The average age was 9.1 years at T1 and 11.3 years at T2. Mandibular segmentation and superimposition were performed to obtain linear and angular measurements at different axial levels. Results: At the superior (mental foramen) axial level, transverse growth between the buccal surfaces gradually increased from the premolars to the ramus. At the inferior axial level, significant transverse growth differences were detected between the ramus and the dentition regions. In contrast, between the lingual surfaces, both superior and inferior levels showed minimal change in the region under the dentition and a significant amount of resorption in the ramus region. This difference between buccal and lingual surface changes led to a mandibular body angulation change in the premolar and molar regions. In contrast, the overall mandibular body angulation measured from the posterior-most border of the mandible to the symphysis remained the same. Differences were detected between males and females, with males tending to exhibit greater transverse growth in the ramus region at the inferior level. Conclusions: The mandibular body exhibited different transverse growth patterns at different axial levels. Differences were also found between genders. Clinical relevance: An in-depth understanding of craniofacial growth and development is crucial to diagnosis and treatment planning. The current study provides additional insight into the transverse growth of the mandible. [ABSTRACT FROM AUTHOR]

Background: Bones play a vital part in the process of individual identification in medico-legal cases, as they resist decomposition for a long period. The foramen magnum, which is located at the cranial base, is also a good parameter for identifications with reasonable accuracy. The surface area of the foramen magnum can be calculated using 3D reconstructed computer tomography of the head to assess the morphological differences in males and females, which is useful in forensic sciences. Objectives: To measure the antero-posterior length of the foramen magnum, the transverse diameter of the foramen magnum, the surface area of foramen magnum in males and females and to compare surface area of male and female foramen magnum to find morphological difference. Method: CT scan was performed in 40 patients (20+20) in two groups consist male and female, using SIEMENCE SOMATOM 16 SLICE machine, in patients referred to Acharya Vinoba Bhave Rural Hospital for CT head scan with 3D skull. Scan will include the vertex to C3, received images then reconstructed into 3D images. From the 3D images the foramen magnum was measured; anterior-posterior, transverse and surface area in two groups of patients includes males and female. Teixeria's and Radinsky's formulae was used. Descriptive analysis to measure area of foramen magnum. Independent sample T test to determine any significant difference between male and female foramen magnum area and Discriminant analysis. Result: 70% of original group cases were correctly classified using the derived data Conclusion: foramen magnum can be used in forensic science as gender determination tool in the case where other identifying methods are inconclusive and modern imaging technology can be very useful. [ABSTRACT FROM AUTHOR]

Abstract—The propagation time of longitudinal, transverse, and transformed ultrasonic waves in three R65 rail segments is estimated as a function of temperature using a high-speed acoustoelasticity-based microprocessor system. The obtained time dependences and the results of estimating the errors of measuring the time parameters made it possible to calculate the longitudinal stresses over the entire sonic test rail volume in an operating railway track segment at an error of at most 10%. [ABSTRACT FROM AUTHOR]

Introduction. Neurological complications related to epidural anesthesia are rare, but it is necessary to recognize and diagnose them as early as possible, in order to start appropriate therapy and prevent further neurological damage. One of the rare complications of regional anesthesia described in this paper is longitudinal extensive transversal myelitis (LETM). Case report. A 32-year-old patient, who gave birth by Caesarean section in due term, developed LETM the very same day. Considering the neuroradiological findings that indicated to the long central lesion in the thoracic and lumbar spine, and an expected reaction to the applied immunotherapy (immunosuppressive therapy and therapeutic plasma exchange), a diagnosis of LETM was made. Even with all the therapy and regression of the lesions, the patient could not stand up without support. During the subsequent treatment, according to the instructions of the physiatrist, physical therapy was carried out, to which the patient responded slowly but favorably, with a gradual return of the function of the lower extremities. Conclusion. Early diagnosis and timely treatment of LETM are crucial for the prognosis of the disease and the early recovery of the patient. [ABSTRACT FROM AUTHOR]

BackgroundNeurologic toxicities with immune therapy are rare, but can cause devastating and often permanent injury when they occur. Although there is increasing interest in the potential synergism between immune therapy and radiation, it is possible that such combinations may lead to a greater number or increased severity of immune-related adverse events. We present here a case of extensive and progressive transverse myelitis following combined therapy, which did not improve until treatment with infliximab. This case highlights the unmet need for treatment of adverse events that are refractory to consensus recommendations, and may ultimately require further study and incorporation into future published guidelines.Case presentationWe report a case of a 68-year-old with metastatic melanoma, who developed transverse myelitis in the setting of immune checkpoint blockade and spinal irradiation for vertebral metastases. Despite management according to published consensus guidelines: cessation of immune therapy, high-dose steroids, and plasmapheresis, he continued to deteriorate neurologically, and imaging revealed a progressive and ascending transverse myelitis. The patient was then treated with infliximab, and demonstrated dramatic imaging and modest clinical improvement following the first treatment cycle.ConclusionsThis is the first report describing the successful use of infliximab in immune therapy and radiation-related transverse myelitis that was not responding to recommended therapy. Evaluation of additional treatment options such as infliximab for high-grade immune-related neurologic toxicities is warranted, and may be needed earlier in the disease process to prevent significant morbidity. The adverse effects of immune therapy when used in combination with radiation also require further investigation.

In this study, the effects of surface roughness and thermal on slider bearings with turbulent fluid film were examined using the Streamline Upwind Petrov–Galerkin (SUPG)-Finite Element Method. Using the assumption that roughness is stochastic and has a Gaussian random distribution, one-dimensional transverse and longitudinal surface roughness models were taken into consideration. The texture of the surface's irregularity is changed into a regular domain for computational efficiency. To derive the modified Reynolds equation for turbulent lubrication, the Ng-Pan turbulent model is used. For all local Reynolds values, the pressure distribution of the combined effect is less than the thermal and surface roughness influences of the one-dimensional longitudinal surface roughness, which is a reduction of 16% in load-carrying capacity performance and 3% decrease in friction force, for non-parallel (w = 0.4) between the surface roughness effect and the combined effect condition, respectively. However, the pressure distribution of the thermal effect is smaller than the combined and surface roughness effects in the transverse, one-dimensional roughness model for all local Reynolds values, which is a reduction of 33% in load–carrying capacity performance and 13% decrease in friction force, for non-parallel (w = 0.4) between the surface roughness effect and the thermal effect condition, respectively. Moreover, the combined effects at various temperatures are examined. As a result, the load-carrying capacity performance is better in the case where the pad temperature is lower than the slider in both longitudinal and transverse models. The performance of a slider bearing will generally be improved by taking surface roughness and the coefficients of turbulent lubrication equations into account. Tables and figures were used to present the results. [ABSTRACT FROM AUTHOR]

The dynamic elasticity modulus (Ed) is the most commonly usEd indexes for nondestructive testing to represent the internal damage of hydraulic concrete. Samples with a specific size is requirEd when the transverse resonance method was usEd to detect the Ed, resulting in a limitation for field tests. The impact-echo method can make up defects of traditional detection methods for frost-resistance testing, such as the evaluation via the loss of mass or strength. The feasibility of the impact-echo method to obtain the relative Ed is explorEd to detect the frost-resistance property of large-volume hydraulic concretes on site. Results show that the impact-echo method can replace the traditional resonance frequency method to evaluate the frost resistance of concrete, and has advantages of high accuracy, easy to operate, and not affecting by the aggregate size and size effect of samples. The dynamic elastic modulus of concrete detectEd by the impact-echo method has little difference with that obtainEd by the traditional resonance method. The one-dimensional elastic wave velocity of concrete has a good linear correlation with the transverse resonance frequency. The freeze-thaw damage occurrEd from the surface to the inner layer, and the surface is expectEd to be the most vulnerable part for the freeze-thaw damage. It is expectEd to monitor and track the degradation of the frost resistance of an actual structure by frequently detecting the P-wave velocity on site, which avoids coring again. [ABSTRACT FROM AUTHOR]

Synchronous volvulus of the transverse and sigmoid colon is an exceedingly rare clinical presentation. The dual location of strangulation constitutes a critical surgical emergency due to the heightened risk of intestinal necrosis and septic shock. Given the rarity of this condition, there is a notable paucity of detailed information in the literature, and the management strategies are poorly codified. We report the case of a 23-year-old man with a history of bowel transit disorders (diarrhea and constipation), who was admitted as an emergency with typical signs of acute large bowel obstruction. Initial diagnosis of sigmoid volvulus was retained; however, intraoperative findings revealed an associated volvulus of both the transverse and sigmoid colon. A left colectomy was performed followed by colorectal anastomosis. The postoperative period was uneventful. Synchronous volvulus of the transverse and sigmoid colon is an extremely rare occurrence; it should be considered as one of the differential diagnoses of acute large bowel obstruction. There is scarcity of information in the literature regarding synchronous sigmoid and transverse colon volvulus. Synchronous volvulus of the transverse and sigmoid colon is an exceedingly rare clinical entity. Diagnosing this condition can be difficult and the management effectiveness remains controversial. It is presumed that sigmoid volvulus is the initial event; therefore, emphasizing the need for early surgical intervention for sigmoid volvulus could potentially improve outcomes. • The synchronous occurrence of a sigmoid colon and transverse colon volvulus is exceptional. • The diagnosis of this double volvulus is most often made intraoperatively. • The literature concerning its description is sparse and the treatment options are poorly codified. • The prognosis of this clinical presentation is good, only one death for 14 cases in 25 years [ABSTRACT FROM AUTHOR]

ObjectiveTo evaluate the diagnostic performance of different ultrasound sections of thyroid nodule (TN) using computer-aided diagnosis system based on artificial intelligence (AI-CADS) in predicting thyroid malignancy.Materials and methodsThis is a retrospective study. From January 2019 to July 2019, patients with preoperative thyroid ultrasound data and postoperative pathological results were enrolled, which were divided into two groups: lower risk group (ACR TI-RADS 1, 2 and 3) and higher risk group (ACR TI-RADS 4 and 5). The malignant risk scores (MRS) of TNs were obtained from longitudinal and transverse sections using AI-CADS. The diagnostic performance of AI-CADS and the consistency of each US characteristic were evaluated between these sections. The receiver operating characteristic (ROC) curve and the Cohen κ-statistic were performed.ResultsA total of 203 patients (45.61 ± 11.59 years, 163 female) with 221 TNs were enrolled. The area under the ROC curve (AUC) of criterion 3 [0.86 (95%CI: 0.80~0.91)] was lower than criterion 1 [0.94 (95%CI: 0.90~ 0.99)], 2 [0.93 (95%CI: 0.89~0.97)] and 4 [0.94 (95%CI: 0.90, 0.99)] significantly (P0.60).ConclusionThe diagnostic performance of computer-aided diagnosis system based on artificial intelligence (AI-CADS) in longitudinal and transverse ultrasonic views for differentiating thyroid nodules (TN) was different, which was higher in the transverse section. It was more dependent on the section for the AI-CADS diagnosis of suspected malignant TNs.

Construction works are frequently recurring events within highway networks, temporarily altering the characteristics of the traffic flow and hence of the bridge loading process. Consequently, highway bridge superstructures usually carrying unidirectional traffic might have to face modified configurations, with possibly altered lane widths and transverse lane positions, or even an increased number of lanes and the occurrence of bidirectional traffic flow. While usually covering only short periods compared to the average service life of a bridge, such scenarios might represent extreme loading situations, potentially dominating the traffic loading process. Therefore, their consideration and accurate modeling in the course of traffic load assessment and development of object-specific traffic load models are of utmost importance. The presented study analyzes data from bridge monitoring along federal highway A92 in Southern Germany. The data covers standard and different modified lane configurations due to construction works. Besides analyzing the effects on traffic flow characteristics and resulting occurrence rates of multiple truck presence on the bridge, the consequences for load effects and their extreme value behavior are also evaluated. The findings support verification of related code background works and can serve as base and guidance for future research efforts on bridge load modeling in this context. [ABSTRACT FROM AUTHOR]

Bismaleimide-based hybrid fiber composites (BMI) with their expanded thermomechanical properties have been broadly utilized in Aircraft primary applications. The supplanting of carbon fiber with other fiber (kevlar/glass/basalt) is redone to the requirements of the business. To maintain the surface quality, the hybrid composites can be machined with unconventional methods like Abrasive Water jet Machining. In this work, the exploratory examination of interaction boundaries, such as Water pressure (Wp), Transverse speed (Ts), Standoff distance (SOD), Abrasive mass flow rate (ma) of AWJM on hybrid BMI composites was done. Experiments were conducted based on Design of Experiments created from Response surface strategy utilizing Central Composite Design (CCD) and the impact of interaction boundaries on kerf taper and surface roughness were analyzed. The experimental outcomes showed that for the minimum kerf angle, the significant parameters were transverse speed, water pressure, and abrasive flow rate and for minimum surface roughness, transverse speed was the significant parameter. The microstructure analysis revealed that plowing deformation of fiber and abrasive particle embedment at high speed and mass flow rate led to delamination of fiber, which was limited by optimal parameters essentially diminishing kerf taper and surface roughness. [ABSTRACT FROM AUTHOR]

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The cranial base has a crucial effect on the position of the maxilla and mandible. This study aims to investigate the relationship between the cranial base sagittal and transverse dimensions in different skeletal patterns. This is a retrospective study of pre-existing CBCT images of 132 subjects (60 males and 72 females) from Saudi Arabia with a mean age of 35 years old. The grouping of the subjects was based on the ANB angle of Steiner's analysis. One-way ANOVA was used to compare the means of the sagittal and transverse dimensions between different skeletal patterns, followed by a post hoc test for individual comparisons. Logistic regression analysis was performed to test the relationship between gender, age, and cephalometric values between the three groups. The significance level was 0.05. One-way ANOVA revealed a statistically significant difference in posterior cranial base length (p < 0.05) and total cranial base length (p < 0.05) among different skeletal patterns. Tukey's post hoc analysis showed that skeletal class II had a smaller posterior cranial base and total cranial base length when compared to the other groups. The class II skeletal pattern has a smaller posterior cranial base and total cranial base when compared to skeletal class I and class III skeletal patterns. [ABSTRACT FROM AUTHOR]

We show that a link in an open book can be realized as a strongly quasipositive braid if and only if it bounds a Legendrian ribbon with respect to the associated contact structure. This generalizes a result due to Baader and Ishikawa for links in the three-sphere. We highlight some related techniques for determining whether or not a link is strongly quasipositive, emphasizing applications to fibered links and satellites. [ABSTRACT FROM AUTHOR]

Our aim was to clarify the anatomy and function of the retinacular ligaments. Forty-eight fingers were dissected and the thickness of the oblique retinacular ligament (ORL) was graded. In four fingers, the motion in the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints was subjected to an in-depth analysis before and after sectioning of either the lateral bands (LB) or the ORLs. The function of the ORLs in restricting flexion of the DIP joint with full extension of the PIP joint was measured in 10 fingers. An ORL could be identified on both sides in all 48 fingers. The distribution of the insertion on the proximal phalanx was 7/96 (7%) in the distal third, 70/96 (73%) in the middle third and 19/96 (20%) in the proximal third. Among the specimens, 29% were graded as having a strong bundle of fibers, 51% as having well-defined and regular fibers and 20% as having thin and sparse fibers. With the PIP joint extended, there was a statistically significant increase in flexion of the DIP joint after the ORL was cut. After the LB was sectioned, the ORL was able to extend the DIP joint with an extension lag of 10-22°. Cutting the ORL did not affect the ability to extend that joint. We conclude that the retinacular ligaments are consistent. Their major role is not connected with finger movement, but to provide stabilizing links between the PIP and DIP joints. They are active in not only specific, uncommon finger positions but also in ordinary use of the fingers., (© 2023 American Association of Clinical Anatomists and British Association of Clinical Anatomists.)

Background : Evaluating patients with ascending sensorimotor deficits has a broad differential diagnosis at initial presentation which can be further narrowed upon neurologic examination but may represent a diagnostic and therapeutic dilemma in light of findings raising suspicion for multiple possible etiologies. Data Collection : In this case, a 29-year-old patient presented with ascending bilateral lower extremity sensory loss, paresthesias, and weakness which progressed to the inability to ambulate. Conclusions : This case highlights the diagnostic approach to patients with bilateral lower extremity sensorimotor deficits, discusses the development of a comprehensive differential diagnosis, and further evaluates the most likely etiologies. Furthermore, this case reviews complexities related to clinical reasoning in the setting of diagnostic uncertainty, particularly when the neurologic structures affected portend high risk for severe disability and early treatment may improve outcome., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2024.)

Background: This study aimed to investigate the differences in the buccolingual inclination and transverse width of maxillary and mandibular first molars among different vertical facial types., Methods: In all, 78 samples were divided into three groups based on the GoGn-SN angle: the low-angle group (n = 26, mean age=24.21±5.11), average-angle group (n = 26, mean age=22.66±3.72), and high-angle group (n = 26, mean age=22.23±2.43). Cone beam computed tomography (CBCT) measurements were used to assess the buccolingual inclination of the axis of the maxillary and mandibular first molars, as well as the buccolingual inclination of the alveolar bone, the dental arch width, and the basal bone width. One-way ANOVA, the LSD test, and Pearson correlation analysis were performed., Results: The high-angle group showed significantly greater lingual inclination of the maxillary alveolar bone than the low-angle group and average-angle group (p < 0.001; p < 0.05). The difference in buccolingual inclination of the axis of the maxillary first molar and the alveolar bone was significantly greater in the high-angle group than in the low-angle group (p < 0.05). Both the maxillary and mandibular dental arch were significantly narrower in the high-angle group than in the other two groups. The mandibular basal bone was also significantly narrower in the high-angle group than in the low-angle group and average-angle group (p < 0.001; p < 0.01)., Conclusions: The alveolar bone of maxillary first molar in the high-angle group was more palatal inclined than that the low-angle group and the average-angle group, which suggests that orthodontists should pay more attention to the root-bone relationship in the high-angle group during expansion treatment to prevent bone fenestration and dehiscense., Competing Interests: Declaration of competing interest None., (Copyright © 2024 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)

Background and objectives: Chronic nonspecific back pain is a common clinical disease typically treated by ultrasound-guided spinal injection. This minimally invasive treatment targets the posterior ramus of the spinal nerve (PRSN). The target of the medial branch is clear, but there is unclear target for the intermediate and lateral branches. This study attempted to observe the distribution of PRSN in the dorsal region of transverse process to provide a more detailed anatomical basis for treating spinal pain.Methods: The present study was conducted on 16 transverse processes of six adult male embalmed corpses. The dorsal area of the transverse process was divided into three equal zones, which are zone I, zone II and zone III from inside to outside. The origin, distribution, quantity, transverse diameter, and relationship with the bone structure of the PRSN on the transverse process were observed.Results: Sixty PRSNs were found in the lumbar of six cadavers, of which 48 were divided into three branches, and 12 PRSNs were divided into two branches. The intermediate branch is mainly distributed in zone I, and the lateral branch is mainly distributed in zone II. Twenty-nine communicating branches were found in 48 adjacent segments of six specimens, all of which originated from the intermediate branch of the previous segment and connected with the lateral branch of the next segment.Conclusion: This anatomical study describing the PRSN may have important clinical significance for spinal surgeons. Understanding the bony localization targets of the PRSN and the links between the PRSNs may benefit patients with low back pain who receive spinal injections.

Patella fractures in children are rare accounting for 1 % of all paediatric fractures. Rarer still are transverse patella fractures in children with only 1 case previously described in the literature of a child less than the age of 6. We present the second case in the literature of a transverse patella fracture in a child, and the only case of a transverse fracture in a partially ossified patella in a 5-year-old. Our patient suffered an open patella fracture following fall with a flexed knee onto a broken tile. The case was successfully managed with adult fixation principles of patella fractures with a tension band wire construct. The patient had regular follow-up with knee radiographs showing a well healed fracture and a good range of motion of the knee at 3 months. The hardware was subsequently removed with no complications. In conclusion, we present an extremely rare case of an open transverse patella fracture in a child, utilising adult fixation principles of a patella which resulted in a successful outcome for the patient.

In quantum spin systems, lower energy state for a nuclear spin in an external field is spin ( + 1 / 2 ) while the higher energy state is spin ( - 1 / 2 ). A continuum analog to the discrete model led to nonlinear Schrodinger equation (NLSE) with higher order dispersion. Recently, a model equation with bilinear and biquadratic interactions in the (2 + 1) dimensional Heisenberg ferromagnetic spin chain (HFSC), was derived in the literature. This model equation is a NLSE with quartic dispersion and fifth degree nonlinearity, and it was rarely considered in the literature. The, only, work done has shown solitons solutions. This motivated us to consider this problem for inspecting the multiple characteristics of the HFSC in space-time. Here, the exact solutions of the HFSC biquadratic model equation are obtained by using the unified method (UM). In applications, it is found the UM is of low time cost in symbolic computations. So, we think that it prevails the known methods. The solutions obtained are evaluated numerically and shown in figures.These figures reveal that the solutions exhibit longitudinal-transverse (L-T) solitons chains (SCs) with presence (or absence) of tunneling, depending on the values of the parameters of high dispersivity and high nonlinearity. Also, L-T zig-zag SCs are observed, where pulses with higher amplitudes (or gaps) occur along a characteristic line. Furthermore, L-TSCs modulation along the space axes is shown. It is remarked that the contour plots show complex lattice waves, which is relevant to the spin chain system. So, the present work reveals new solitons structures induced by bilinear-biquadratic interactions of HFSC. [ABSTRACT FROM AUTHOR]

Objective: To determine whether the transverse dimensions of the maxillary arch of 5-year-old children with unilateral cleft lip and palate (UCLP) have changed following centralization of cleft services in the United Kingdom. Design: Retrospective cross-sectional study. Setting: Digital analysis of UCLP maxillary dental casts. Participants: All available maxillary dental casts from 5-year-old participants of the Clinical Standards Advisory Group (CSAG, N = 114) and Cleft Care UK (CCUK, N = 175) studies. Interventions: Quantitative measurements of the intercanine width (ICW), intermolar width (IMW), and the distance from the midline to the greater and lesser side canine (GC/LC) and greater side and lesser side second primary molar (GE/LE). Degree measurements of the greater and lesser arch form angles, arch length, anterior palatal depth (APD), and posterior palatal depth were also measured. Main outcome: Differences between the transverse dimensions of the maxillary arch for the CSAG and CCUK cohorts. Results: In 5 (ICW, IMW, LC, LE, and APD) of the 11 measurements, there was a statistically significant difference between the CSAG and CCUK cohorts. In all of these, the CCUK values were greater than CSAG. Conclusions: There have been small but positive improvements for the transverse maxillary dimensions since centralization of the UK cleft service. [ABSTRACT FROM AUTHOR]