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Copyright of Physiotherapy Canada is the property of University of Toronto Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nouveau Praticien Vétérinaire Canine & Féline is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nouveau Praticien Vétérinaire Canine & Féline is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nouveau Praticien Vétérinaire Canine & Féline is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Silicone oil tamponade is one of the therapeutic methods used in complex retinal detachments caused by inferior and/or posterior dehiscence. However, it can cause complications, in particular, silicone oil migration into the anterior chamber or "invered hypopion". We here report the case of a patient presenting to the Emergency Department with a sudden decrease in visual acuity in the right eye secondary to a coughing fit. Ophthalmological examination revealed uncorrected visual acuity reduced to perception of hand movements. Intraocular pressure was 27mmHg. The examination of ocular annexes was normal. Slitlamp examination of the anterior segment revealed emulsified silicone oil suspended in the anterior chamber, hiding half of the pupil and forming 'reverse pseudo-hypopion' or silicone oil "hyperpion": the reflection produced by intraocular implant was visible. Fundus was inaccessible. The contralateral eye examination was normal. Treatment was based on anterior chamber washout and aspiration of silicone oil. The patient's outcome was favorable: visual acuity improved to 3/10 with normal intraocular pressure. [ABSTRACT FROM AUTHOR]

Aberrant course of the internal carotid artery is a rare congenital malformation. Aberrant course of cervical internal carotid artery accounts for 5% of cases. Several cases of fatal hemorrhage due to an injury to the aberrant internal carotid artery have been observed in patients undergoing pharyngeal surgery procedures. This was associated with a lack of detection during surgery. Ear nose and throat (ENT) practitioner need to know it. We here report a case of aberrant internal carotid manifesting as chronic cough due to the contact of the epiglottis with the pharyngeal mass caused by the aberrant artery. The patient was treated for chronic lung disease without success. This particular anatomical condition should be suspected in patients with pharyngeal mass before any invasive procedure. [ABSTRACT FROM AUTHOR]

Les troubles fonctionnels respiratoires ou désordres respiratoires somatoformes (DRS) sont fréquents en pédiatrie. Ce sont des symptômes respiratoires ou des plaintes concernant la respiration, pour lesquels une étiologie organique n'est pas actuellement identifiée. Les DRS sont isolés ou souvent associés à une pathologie organique, avant tout l'asthme. Face à une gêne respiratoire, surtout en cas de discordance entre la plainte et les signes objectifs, il faut les évoquer et analyser la sémiologie respiratoire, ne pas hésiter à demander à l'enfant de reproduire le symptôme, s'aider d'autoquestionnaire, demander de filmer au domicile un épisode. La prise en charge est indispensable pour éviter une consommation médicale inadaptée, et la persistance des signes dans le temps. Functional respiratory disorders or somatoform respiratory disorders (FRD) are common in pediatrics. These are respiratory symptoms, or complaints about breathing, for which an organic etiology is not currently identified. FRD are isolated or associated with an organic pathology, above all asthma. Faced with respiratory discomfort, especially in the event of a discrepancy between the complaint and the objective signs, it is necessary to analyze the respiratory semiology, do not hesitate to ask the child to reproduce the symptom, use the self-questionnaire; ask to film it at home. Management is essential to avoid inappropriate medical consumption, persistence of signs over time. [ABSTRACT FROM AUTHOR]

Background: Current literature highlights the difficulty in identifying an optimal educational technique for maintaining continence during cough., Objective: To characterize the effects of an educational intervention focusing on neutral posture during cough in women with cough-induced urinary incontinence (UI)., Methods: This interventional study design included women with cough-induced UI. We recorded PFMs surface electromyographic (sEMG) peak activity, and assessed symptoms and quality of life (QoL) 6 weeks after the intervention. The effect of the experimental situation was estimated using a linear mixed model, sEMG measurements during coughing were indexed to each situation and adjusted to the resting value at, and a moderation analysis was used., Results/findings: Eighteen participants were included. The measurement situations (control versus experimental) did not have a statistically significant impact on sEMG peak activity during coughing: mean effect [95% CI] 3.42 [-1.28; 7.66]. Six weeks post-intervention, participants reported statistically significant decrease in urinary symptoms (P=0.0246) and significant improvement in QoL (P=0.00776). This was also particularly marked on the dimension related to effort activities (P=0.00162)., Conclusion: This study suggests that a brief educational intervention focusing on neutral posture during cough, without voluntary pre-contraction of the PFMs, has no clinically significant influence on sEMG peak activity of the PFMs in women with cough-induced UI. However, this intervention can lead to a significant improvement in urinary symptoms and QoL at 6 weeks. These improvements seem to be independent of electromyographic PFMs peak activity recorded during cough. As such, our preliminary results pave the way for future research., Level of Evidence: NP4., (Copyright © 2023 Elsevier Masson SAS. All rights reserved.)

Aberrant internal carotid artery is a rare birth defect. It occurs when the artery takes an abnormal course, the discovery of which is fortuitous but in the presence of dysphonia or chronic cough; this anomaly remains a diagnosis of exclusion. Cervicothoracic CT scan with injection of contrast product confirms the diagnosis. We report the case of a 64-year-old patient who presented with an aberrant course of an aneurysmal internal carotid artery revealed by dysphonia and chronic cough. [ABSTRACT FROM AUTHOR]

Aberrant internal carotid artery is a rare birth defect. It occurs when the artery takes an abnormal course, the discovery of which is fortuitous but in the presence of dysphonia or chronic cough; this anomaly remains a diagnosis of exclusion. Cervicothoracic CT scan with injection of contrast product confirms the diagnosis. We report the case of a 64-year-old patient who presented with an aberrant course of an aneurysmal internal carotid artery revealed by dysphonia and chronic cough., Competing Interests: Déclaration de liens d'intérêts Les auteurs déclarent ne pas avoir de liens d'intérêts., (Copyright © 2023 Elsevier Masson SAS. All rights reserved.)

Résumé Les bronchiolites sont définies par une inflammation non spécifique et/ou une fibrose des petites voies aériennes. La polyarthrite rhumatoïde et le syndrome de Gougerot-Sjögren sont les deux principales connectivites associées à un risque de bronchiolite. La prévalence des bronchiolites au cours de ces maladies est difficile à évaluer en l’absence d’uniformité des critères utilisés. La plupart des atteintes bronchiolaires survenant dans ce contexte sont cependant peu ou pas symptomatiques. Des formes sévères entraînant un handicap respiratoire et pouvant mettre en jeu le pronostic vital sont possibles, bien que rares. Le diagnostic repose sur les EFR et le scanner thoracique ; une confirmation histologique est rarement nécessaire. Le traitement associe des mesures non spécifiques (bronchodilatateurs, vaccination, réhabilitation respiratoire), éventuellement des macrolides au long cours, et parfois un essai de corticoïdes avec ou sans immunosuppresseur. Rheumatoid arthritis and Sjogren's syndrome are the two main connective tissue diseases associated with bronchiolar disorders, including constrictive bronchiolitis and cellular bronchiolitis. The prevalence of bronchiolitis is difficult to assess. Most patients have little or no symptoms. More severe and life-threatening bronchiolitis is possible, although rare. The diagnosis of bronchiolar involvement is based on lung imaging and lung function tests; histological proof is usually not required. Treatment includes non-specific measures (bronchodilators, vaccination, rehabilitation), long-term macrolides and a corticosteroid and/or immunosuppressive trial. [ABSTRACT FROM AUTHOR]

Résumé La toux est un symptôme pour lequel le patient s’automédique volontiers. Toutefois, le rôle du pharmacien dans le choix du médicament adapté est primordial. Les antitussifs ne sont indiqués que dans les toux invalidantes. Compte tenu d’effets indésirables non négligeables, leur utilisation suppose d’en avoir évalué le rapport bénéfice-risque. Summary The cough is a symptom for which the patient freely self-medicates. However, the role of the pharmacist in the choice of a suitable medicine is essential. Cough medicines are only indicated in cases of debilitating coughs. Due to the potentially serious adverse effects, it is important to assess the risk-benefit ratio before using them. [ABSTRACT FROM AUTHOR]

Copyright of Reanimation is the property of Lavoisier and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Sociologie de l' Art is the property of L'Harmattan Edition Diffusion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Phytothérapie is the property of John Libbey Eurotext Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Reanimation is the property of Lavoisier and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Sociologie de l' Art is the property of L'Harmattan Edition Diffusion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Bien que la toux soit un motif de consultation médicale fréquent, il n’en reste pas moins que les structures incriminées dans ce mécanisme sont longtemps restées inconnues. L’étude de la physiopathologie de la toux, de la mécanique respiratoire et de la clairance muco-ciliaire est essentielle dans la démarche de mise en œuvre d’une thérapeutique antitussive. Summary While a cough is a common reason for seeking medical advice, the structures involved in this mechanism are still relatively unknown. Studying the physiopathology of the cough, the mechanics of the respiratory system and mucociliary clearance is essential in order to be able to implement a suitable cough treatment. [ABSTRACT FROM AUTHOR]

Résumé: La toux désespérante de l’enfant constitue une source d’angoisse pour les familles et un défi de prises en charge diagnostique et thérapeutique pour le clinicien. Une démarche rigoureuse avant tout clinique est essentielle pour ne pas méconnaître une cause organique nécessitant un traitement spécifique. Les troubles somatoformes constituent un groupe étiologique difficile à diagnostiquer et à prendre en charge. L’asthme ű difficile à traiter Ƈ est aussi une situation complexe, où la persistance de la toux doit faire vérifier la validité du diagnostic d’asthme et rechercher des pathologies associées, notamment le syndrome d’hyperventilation et la dysfonction des cordes vocales. Dans la plupart des cas, aucun signe d’alerte n’est présent mais le caractère répété du symptôme est vécu comme insupportable par les familles. Une écoute des parents et des explications simples permettent d’apaiser leurs craintes, d’éviter tout nomadisme médical, et de les aider à mieux tolérer ce symptôme. [ABSTRACT FROM AUTHOR]

La toux et les maux de gorge sont des maux d’automne et d’hiver courants et souvent bénins. Le conseil officinal peut en général suffire à les prendre en charge. Toutefois, ces symptômes ne doivent pas être pris à la légère et il est indispensable d’analyser les plaintes des patients et de détecter les signes d’alerte qui justifient une consultation médicale. [ABSTRACT FROM AUTHOR]

Introduction: The International Continence Society (ICS) recommends a control of the good pressure transmission by a coughing effort during cystometry. While poor transmission is sometimes observed in routine practice, other maneuvers can also be proposed. The main objective of this study was to determine if there is a better maneuver to evaluate the pressure transmission ratio between the abdominal cavity and the bladder., Methods: We performed a prospective, consecutive, single-center study in a tertiary neuro-urology department in 31 subjects. During a cystometry, each patient was asked to perform at 0ml and 100ml of bladder filling, a cough effort, an abdominal push and a Valsalva maneuver controlled by a manometer. The value of the bladder pressure to abdominal pressure ratio was collected manually. The average variations were compared between each maneuver for the same volume of replenishment and between the 2 volumes of replenishment studied., Results: At 0ml of filling, the difference in pressure variation between the Pves and the Pabd is significantly higher during the cough maneuver compared to the Valsalva (P=0.015), which is not found at 100ml of filling., Conclusion: During bladder filling, the pressure transmission ratios during the 3 maneuvers are equivalent. Coughing or abdominal thrusting, which are easier to perform than the Valsalva maneuver, should be recommended to check the quality of the recording during cystomanometry., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)

Résumé: Dans certaines situations, les patients peuvent présenter des difficultés d’ordre respiratoire en cours de radiothérapie, telles qu’une toux, une dyspnée ou des hémoptysies, ce qui peut entraver le déroulement des traitements et en altérer la précision. Les stratégies cliniques et techniques permettant de prévenir et de pallier à ce genre de situations sont détaillées. [ABSTRACT FROM AUTHOR]

Introduction: We are reporting the case of a 64-year-old patient with chronic cough who has been diagnosed with an intercostal hernia with pleural and hepatic content associated with a diaphragmatic hernia of non-traumatic origin., Case Report: The patient was treated for an acutely febrile cough with signs of respiratory distress. Thoracic scan showed an intercostal hernia containing an encysted hematoma and a right anterior diaphragmatic hernia with epiploic content. The COVID PCR was negative. This is one of the rare reported cases of intercostal hernia associated with a homolateral diaphragmatic rupture. Visceral and thoracic surgery enabled treatment of the two hernial orifices by raphy as well as omentectomy of the necrotic omentum ascending to the right pulmonary hilum., Conclusion: These two parietal complications of chronic cough should be considered in case of intercostal flap or acute respiratory distress. Surgery must then be carried out as a matter of urgency to reduce the content of the hernias and treat the musculoaponeurotic dehiscent orifices., (Copyright © 2022 SPLF. Published by Elsevier Masson SAS. All rights reserved.)

Copyright of West African Journal of Medicine is the property of West African Journal of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pratique Medicale et Chirurgicale de l'Animal de Compagnie is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives To identify existing respiratory hygiene risk practices, and guide the development of interventions for improving respiratory hygiene. Methods We selected a convenience sample of 80 households and 20 schools in two densely populated communities in Bangladesh, one urban and one rural. We observed and recorded respiratory hygiene events with potential to spread viruses such as coughing, sneezing, spitting and nasal cleaning using a standardized assessment tool. Results In 907 (81%) of 1122 observed events, households’ participants coughed or sneezed into the air (i.e. uncovered), 119 (11%) into their hands and 83 (7%) into their clothing. Twenty-two per cent of women covered their coughs and sneezes compared to 13% of men (OR 2.6, 95% CI 1.6–4.3). Twenty-seven per cent of persons living in households with a reported monthly income of >72.6 US$ covered their coughs or sneezes compared to 13% of persons living in households with lower income (OR 3.2, 95% CI 1.6–6.2). In 956 (85%) of 1126 events, school participants coughed or sneezed into the air and 142 (13%) into their hands. Twenty-seven per cent of coughs/sneezes in rural schools were covered compared to 10% of coughs/sneezes in urban schools (OR 2.3, 95% CI 1.5–3.6). Hand washing was never observed after participants coughed or sneezed into their hands. Conclusion There is an urgent need to develop culturally appropriate, cost-effective and scalable interventions to improve respiratory hygiene practices and to assess their effectiveness in reducing respiratory pathogen transmission. [ABSTRACT FROM AUTHOR]

Objectives To assess diagnosis and management of suspected pulmonary tuberculosis (TB) among patients with respiratory complaints attending Comprehensive Health Centers (CHCs) in Afghanistan. Methods Consecutive consenting patients presenting with respiratory complaints at 24 health centres in eight provinces were enrolled between November 2005 and February 2006. Demographics, health histories, clinic provider and study representative exam findings and diagnoses, and diagnostic test results were recorded. Correlates of TB-suggestive symptoms (defined as cough >2 weeks and/or haemoptysis) were assessed by logistic regression. Results There were 1401 participants; 24.6% ( n = 345) were children (age 17 or under). The TB-suggestive symptoms of cough >2 weeks and/or haemoptysis were reported by 407 (31.3%) and 44(3.3%), respectively, with 39 participants reporting both symptoms. Of 413 participants reporting TB-suggestive symptoms, only 178 (43%) were diagnosed as having suspected TB; 22.0% received no clinical diagnosis. Suspected TB was significantly associated with having a household member residing in a refugee camp within the last 2 years (OR = 6.0; 95% CI: 4.1–8.7), seven or more people sleeping in the same room (OR = 1.9; 95% CI: 1.4–2.6) and cooking with a wood fire in the sleeping room (OR = 1.6; 95% CI: 1.2–2.2) in univariate analysis. Conclusions Diagnostic sensitivity by the health worker for possible cases of pulmonary TB was low, as 22% of persons with suspected tuberculosis received no diagnosis. Further, some common/chronic respiratory ailments were under-diagnosed. There is great need for improved practical training and continuing education in pulmonary disease diagnosis for clinical health workers. [ABSTRACT FROM AUTHOR]

Résumé Durant la grossesse, la prise en charge d’une rhinite ou d’une irritation de la gorge repose avant tout sur le respect des règles d’hygiène de vie ainsi que sur des mesures non pharmacologiques. La fièvre doit amener à consulter un médecin. Summary During pregnancy, the treatment of rhinitis or a sore throat is based above all on the respect of personal health practices as well as on non-pharmacological measures. In case of fever, a doctor should be consulted. [ABSTRACT FROM AUTHOR]

Copyright of Phytothérapie is the property of John Libbey Eurotext Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract: Wood-related work has been recognized during the past thirty years as a source of respiratory diseases. The prevalence of occupational asthma has been estimated to be between 5 and 15% of all asthma, but its frequency is difficult to evaluate because it is underestimated. Indeed, there is no simple, specific diagnostic test, and monitoring of workers is difficult. The pathophysiology of these reactions is diverse and has not been elucidated for certain types of wood. The case that will be presented illustrates the importance of early diagnosis of occupational asthma. It was possible as a result of teamwork between the occupational physician, the respiratory specialist/allergist and the attending physician. [Copyright &y& Elsevier]

Copyright of Pelvi-Perineologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pelvi-Perineologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Résumé: Une embolie gazeuse cérébrale a été diagnostiquée à l’origine d’un coma survenu chez un homme de 81 ans, porteur de séquelles pulmonaires tuberculeuses, après une quinte de toux associée à une hémoptysie. La tomodensitométrie cérébrale a permis d''objectiver plusieurs emboles gazeux disséminés, tandis qu''une ancienne caverne tuberculeuse parenchymateuse a été mise en évidence par l’exploration thoracique. Malgré la réalisation de plusieurs séances d’oxygénothérapie hyperbare, le décès du patient est survenu au troisième jour dans un tableau de défaillance multiviscérale. Le mécanisme physiopathologique de cette embolie a été recherché afin de comprendre la survenue particulière de ce coma. [Copyright &y& Elsevier]

Résumé: L’œdème pulmonaire se définit comme une accumulation excessive de liquide d’origine endogène dans l’interstitium, les alvéoles et les bronchioles. L’accroissement du flux de drainage lymphatique est la meilleure protection contre l’augmentation du liquide extravasculaire pulmonaire qui résulte de deux mécanismes principaux : l’élévation de la pression hydrostatique capillaire et la modification de la perméabilité de la barrière alvéolocapillaire, ces deux mécanismes étant souvent associés et favorisés par d’autres tels que la baisse de la pression hydrostatique interstitielle, la baisse de la pression oncotique capillaire ou l’insuffisance de drainage lymphatique. Les cardiopathies gauches sont responsables de la plupart des œdèmes pulmonaires « de haute pression » alors que les œdèmes « à haute perméabilité » connaissent des causes très différentes, avec des mécanismes physiopathologiques complexes parfois incomplètement connus. Le tableau clinique est dominé par la toux (souvent absente chez le chat) et la dyspnée. La radiographie thoracique est l’examen complémentaire le mieux adapté pour confirmer la présence d’œdème. Sa vitesse d’évolution peut être très rapide (œdème aigu du poumon) et nécessiter une thérapeutique dans le cadre de l’urgence. Dans cette situation, le repos absolu, l’oxygénothérapie, le recours aux diurétiques de l’anse avec en particulier le furosémide, constituent les premières mesures à prendre pour limiter l’œdème quelle que soit son origine. Cette thérapeutique est complétée par le traitement de la maladie causale. Le pronostic dépend du stade de l’œdème, des conséquences sur la fonction respiratoire et de l’affection qui est à l’origine de l’œdème. Le pronostic des œdèmes « à haute perméabilité » est moins favorable que celui des œdèmes cardiogéniques. [Copyright &y& Elsevier]

La toux est un me´canisme participant a` la de´fense de l’hoˆte particulie`rement afin de prote´ger les voies respiratoires infe´rieures de l’intrusion de substances potentiellement de´le´te`res et de micro-organismes infectieux. La toux reste aussi le symptoˆme-clef d’un large e´ventail de maladies des voies respiratoires. Une toux aigue¨, transitoire, n’a absolument pas la meˆme signification qu’une toux persistante qui peut eˆtre le te´moin d’une pathologie e´volutive grave. Fonde´e sur une approche physiologique et anatomique, la connaissance du processus morbide est indispensable pour la prise en charge spe´cifique de la cause sous-jacente de la toux. Ce n’est que par cette de´marche qu’un traitement efficace peut eˆtre envisage´. [Copyright 2003 Elsevier]

Objectives. – To study the use of mucolytics agents, i.e. acetylcystein and carbocystein, in infants. To evaluate their efficacy and safety for their main indications.Methods. – A prospective one-day survey of prescriptions among 95 office-based pediatricians. A systematic review of the literature.Results. – Among 1327 prescriptions regarding infants, 4.3% were mucolytics agents. Main indications were rhinopharyngitis, isolated cough, and acute bronchitis. Our review did not identify any study of rigorous methodological quality that supported the efficacy or safety of mucolytics agents in infants for their in-label (isolated cough, acute bronchitis) and off-label (rhinopharyngitis) indications. Six cases of infants, aged less than eight months, presenting paradoxical bronchial congestion during a treatment with mucolytics agents, have been reported to the French pharmacovigilance system. No causal relationship was established from these cases because of a possible protopathic bias.Discussion. – Our results concerning mucolytics agents use are similar to those reported by the French Health Care Funds. In addition to the lack of studies on efficacy, no studies on the dose-response relationship were available, leading to suggested dose regimens in the French license of acetylcystein ranging from 44.4 to 16.4 mg kg–1 j–1 between one to 24 months. These dose regimens could predispose to overdosing in the youngest infants as it seems observed in the six reported cases.Conclusion. – In infants, mucolytics agents efficacy has never been demonstrated and some elements suggest poor safety (paradoxical bronchial congestion). [Copyright &y& Elsevier]

We report a case of a fracture of the inferior angle of the scapula related to prolonged cough, without triggering trauma, sport or occupational activity. Bone insufficiency was present in this patient. Stress fractures of the scapula are rare; the fatigue type is the most frequent, associated with sports or occupational activity. We don’t find any published case report about scapula stress fracture related to cough, until rib fractures are frequent in this situation. Repetitive muscular activity of the serratus anterior and major rhomboid on the inferior angle of the scapula during cough may explain this avulsion fracture. [Copyright &y& Elsevier]

Introduction Parmi le groupe hétérogène des neuropathies sensitives héréditaires [1] , l’entité associant neuropathie sensitive, reflux gastro-œsophagien (RGO) et toux chronique a récemment été décrite [2,3] . Seules deux familles australiennes et une portugaise sont rapportées dans la littérature. Notre objectif était de caractériser cliniquement et au niveau électroneuromyographique les patients présentant cette triade au CHU de Bordeaux. Méthodes D’après le registre personnel des neurologues du CHU de Bordeaux, tous les patients ayant une neuropathie sensitive avec toux chronique et RGO ont été réévalués cliniquement entre janvier et avril 2018. Un électroneuromyogramme standardisé et un complément d’examens biologiques étaient également réalisés. Résultats Six patients furent inclus, 4 femmes et 2 hommes, avec une moyenne d’âge de 63 ans. L’âge moyen de début des symptômes pour le RGO, la toux chronique et la neuropathie étaient respectivement de 33, 35,8 et 48,8 ans. Deux patients rapportaient des paresthésies, cinq des douleurs neuropathiques, quatre une hypoesthésie thermique et tous avaient une hypoesthésie protopathique, profonde et épicritique. Quatre patients avaient des antécédents familiaux de troubles sensitifs dont trois avec toux et/ou RGO. Tous les patients avaient une neuropathie sensitive pure asymétrique non-longueur dépendante de type neuronopathie. Deux patients avaient une abolition de tous les potentiels sensitifs, les anticorps anti-FGFR3 sont revenus positifs pour l’un d’entre eux. Pour les autres patients il n’y avait pas d’argument pour une étiologie inflammatoire. Conclusion Nos résultats sont comparables à ceux de la littérature concernant les données cliniques mais diffèrent sur l’électroneuromyogramme. En effet l’atteinte ne prédomine pas aux membres inférieurs et les potentiels sensitifs ne sont pas systématiquement abolis contrairement aux cas publiés. Dans notre cohorte de neuropathies sensitives avec toux et RGO, l’électroneuromyogramme est plutôt en faveur d’une neuronopathie sensitive. Ces résultats nécessitent une évaluation à plus grande échelle et en incluant les apparentés. [ABSTRACT FROM AUTHOR]