21 results on '"thrombosed"'
Search Results
2. Cleaner XT Rotational Thrombectomy: An Efficacious Endovascular Technique for Salvage of Thrombosed Arteriovenous Access and a 12 Month Outcome Analysis.
- Author
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Bong, Tiffany S. H., Aw, Darius K. L., Cheng, Shin Chuen, Choke, Edward T. C., and Tay, Jia Sheng
- Abstract
Purpose: This study aims to describe an efficacious method using Cleaner XT rotational thrombectomy with catheter-directed thrombolysis and drug-eluting balloon angioplasty for the salvage of thrombosed arteriovenous fistulae and grafts. Materials and Methods: Retrospective analysis of all patients with thrombosed hemodialysis accesses who underwent endovascular salvage using the Cleaner XT rotational thrombectomy system at a single institution between June 2019 and September 2020 was performed. Patency was presented as Kaplan-Meier survival curves, and regression analysis was performed to examine predictors of postintervention primary patency and assisted primary patency based on Cox proportional-hazards model. Results: Thirty-four patients with thrombosed accesses underwent Cleaner XT rotational thrombectomy between June 2019 and September 2020. Technical and clinical success were both 100%. Mean procedure time was 62 ± 20 minutes. Mean postintervention primary patency time was 152 ± 51 days; 30, 90, 180, and 365 day postintervention primary patency rates were 89%, 80%, 68%, and 56%, respectively. Mean postintervention-assisted primary patency time was 157 ± 59 days; 30, 90, 180, and 365 day postintervention-assisted primary patency rates were 91%, 82%, 71%, and 59%, and 180 and 365 day secondary patency rates were 97.2% and 94.4%, respectively. Conclusion: The Cleaner XT rotational thrombectomy device demonstrates excellent clinical and technical success rates, with good patency results at all time points up to 12 months postintervention. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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3. Thrombosed orbital varix of the inferior ophthalmic vein: A rare cause of acute unilateral proptosis.
- Author
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Abdelsalam, Ahmed, Ramsay, Ian A., Ehiemua, Uche, Thompson, John W., Fountain, Hayes B., Eatz, Tiffany, Wu, Eva M., Bhatia, Rita G., Lam, Byron L., Tse, David T., and Starke, Robert M.
- Abstract
Background: Orbital varices are rare, accounting for only 0-1.3% of orbital masses. They can be found incidentally or cause mild to serious sequelae, including hemorrhage and optic nerve compression. Case Description: We report a case of a 74-year-old male with progressively painful unilateral proptosis. Imaging revealed the presence of an orbital mass compatible with a thrombosed orbital varix of the inferior ophthalmic vein in the left inferior intraconal space. The patient was medically managed. On a follow-up outpatient clinic visit, he demonstrated remarkable clinical recovery and denied experiencing any symptoms. Follow-up computed tomography scan showed a stable mass with decreased proptosis in the left orbit consistent with the previously diagnosed orbital varix. One-year follow-up orbital magnetic resonance imaging without contrast showed slight increase in the intraconal mass. Conclusion: An orbital varix may present with mild to severe symptoms and management, depending on case severity, ranges from medical treatment to escalated surgical innervation. Our case is one of few progressive unilateral proptosis caused by a thrombosed varix of the inferior ophthalmic vein described in the literature. We encourage further investigation into the causes and epidemiology of orbital varices. [ABSTRACT FROM AUTHOR]
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- 2023
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4. How I do it: surgical clip reconstruction of a large, partially thrombosed, ruptured middle cerebral artery aneurysm.
- Author
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Rinaldo, Lorenzo, Sorenson, Thomas J., Giordan, Enrico, and Rangel Castilla, Leonardo
- Subjects
- *
INTRACRANIAL aneurysms , *CEREBRAL arteries , *ANEURYSMS - Abstract
Background: Ruptured large and partially thrombosed aneurysms are challenging lesions to treat successfully. Methods: We describe the surgical treatment of a large, ruptured partially thrombosed middle cerebral artery (MCA) aneurysm. Once the Sylvian fissure is dissected, temporary clips are placed, and the clot is evacuated with simple microsuction and ultrasonic aspiration. The aneurysm is then carefully clip reconstructed to avoid compromise of the parent vessels. Conclusion: In cases of surgical clipping of large, thrombosed aneurysms, it is important to be aware of a few, but critically important, pitfalls to ensure successful outcome. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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5. What every PA needs to know about anorectal pain.
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Hubbard, Yasmine and Rizzolo, Denise
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ANAL disease diagnosis ,ANUS ,RECTUM ,ABSCESSES ,ANAL fistula ,ANAL diseases ,HEMORRHOIDS ,HOLISTIC medicine ,PATIENT-professional relations ,PAIN ,PHYSICIANS' assistants ,FISSURE in ano ,RECTAL diseases ,SYMPTOMS ,ANATOMY ,DIAGNOSIS ,THERAPEUTICS - Abstract
Anorectal pain is common but often misdiagnosed, and patients may suffer in silence if they are too uncomfortable discussing the topic with their healthcare provider. This article reviews rectal anatomy and the signs and symptoms of several common anorectal conditions and how to manage them. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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6. Treatment of Middle Cerebral Artery Occlusion with Concomitant Partially Thrombosed Aneurysm: a Case Report
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Klapp Oliger, Michel, Hauser, Till-Karsten, Strauss, Franz-Josef, and Ernemann, Ulrike
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- 2020
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7. Successful Endovascular Trapping for Symptomatic Thrombosed Giant Unruptured Aneurysms of the V1 and V2 Segments of the Vertebral Artery: Case Report and Literature Review
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Toshihiro Ishibashi, Yuichi Murayama, Michiyasu Fuga, Yuzuru Hasegawa, Rintaro Tachi, Ryo Nogami, Akihiko Teshigawara, and Toshihide Tanaka
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endovascular treatment ,extracranial vertebral artery aneurysm ,medicine.medical_specialty ,business.industry ,Vertebral artery ,Case Report ,trapping ,thrombosed ,medicine.artery ,giant ,cardiovascular system ,Medicine ,cardiovascular diseases ,Radiology ,business - Abstract
A thrombosed giant aneurysm of the V1 and V2 segments of the vertebral artery (VA) is rare. Therefore, there is controversy regarding its optimal treatment. A case of a symptomatic giant VA aneurysm located in the V1 to V2 segments on the left treated successfully by endovascular trapping of the VA is reported. A 68-year-old woman presented with swelling in the left anterior neck. Computed tomography angiography (CTA) showed a giant aneurysm measuring 47 × 58 × 47 mm3 in the left neck. Ten days after her first visit, she presented with sudden onset of left anterior neck pain. Repeated CTA showed a partial thrombus in the aneurysm. Angiography showed two thrombosed giant aneurysms located in the V1 to V2 segments of the left VA. After endovascular trapping for the aneurysms, the anterior neck pain resolved and the aneurysm gradually shrank. This case demonstrates that endovascular surgery is better than open surgery because it is less invasive. When performing endovascular treatment, trapping will be an alternative strategy for a symptomatic giant thrombotic aneurysm of the V1 and V2 segments of the VA if the patient can tolerate ischemia.
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- 2021
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8. Bilateral and Unilateral Partially Thrombosed Orbital Varices – Report of Two Cases and Literature Review
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Shahi, Niharika, Kisselgoff, David, and Shuster, Anatoly
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- 2020
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9. Unusual Cause for Abdominal Pain in Cirrhosis : Thrombosed Intrahepatic Portal Vein Aneurysms
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Senthil Kumar Aiyappan, Upasana Ranga, and Saveetha Veeraiyan
- Subjects
cirrhosis ,ct ,mri ,portal vein aneurysms ,thrombosed ,Medicine - Abstract
Portal venous system aneurysm is a rare condition with very few reported cases in English literature. With the increasing availability of advanced imaging modalities like Doppler ultrasound, computed tomography and magnetic resonance imaging, portal venous system aneurysms are being increasingly reported. Here, we report a rare case of multiple intrahepatic portal venous system aneurysms complicated by thrombosis in a young patient with chronic liver disease and portal hypertension.
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- 2014
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10. Haskal ZJ, Trerotola S, Dolmatch B, et al. Stent graft versus balloon angioplasty for failing dialysis-access grafts. N Engl J Med. 2010;362:494-503.
- Author
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Georgiadis, George S., Nikolopoulos, Evagelos, Papanas, Nikolaos, and Lazarides, Miltos K.
- Abstract
Background. The leading cause of failure of a prosthetic arteriovenous hemodialysis-access graft is venous anastomotic stenosis. Balloon angioplasty, the first-line therapy, has a tendency to lead to subsequent recoil and restenosis; however, no other therapies have yet proved to be more effective. This study was designed to compare conventional balloon angioplasty with an expanded polytetrafluoroethylene endovascular stent graft for revision of venous anastomotic stenosis in failing hemodialysis grafts. Methods. We conducted a prospective, multicenter trial, randomly assigning 190 patients who were undergoing hemodialysis and who had a venous anastomotic stenosis to undergo either balloon angioplasty alone or balloon angioplasty plus placement of the stent graft. Primary end points included patency of the treatment area and patency of the entire vascular access circuit. Results. At 6 months, the incidence of patency of the treatment area was significantly greater in the stent-graft group than in the balloon-angioplasty group (51% vs. 23%, P < 0.001), as was the incidence of patency of the access circuit (38% vs. 20%, P=0.008). In addition, the incidence of freedom from subsequent interventions at 6 months was significantly greater in the stent-graft group than in the balloon-angioplasty group (32% vs. 16%, P = 0.03 by the log-rank test and P = 0.04 by the Wilcoxon rank-sum test). The incidence of binary restenosis at 6 months was greater in the balloon-angioplasty group than in the stent-graft group (78% vs. 28%, P < 0.001). The incidences of adverse events at 6 months were equivalent in the two treatment groups, with the exception of restenosis, which occurred more frequently in the balloon-angioplasty group (P < 0.001). Conclusions. In this study, percutaneous revision of venous anastomotic stenosis in patients with a prosthetic hemodialysis graft was improved with the use of a stent graft, which appears to provide longer-term and superior patency and freedom from repeat interventions than standard balloon angioplasty. (ClinicalTrials.gov number, NCT00678249.) [ABSTRACT FROM PUBLISHER]
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- 2010
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11. Clinical Outcome of Acute Leg Ischaemia Due to Thrombosed Popliteal Artery Aneurysm: Systematic Review of 895 Cases.
- Author
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Kropman, R.H.J., Schrijver, A.M., Kelder, J.C., Moll, F.L., and de Vries, J.P.P.M.
- Subjects
LEG diseases ,ISCHEMIA ,THROMBOSIS ,ANEURYSMS ,SYSTEMATIC reviews ,LONGITUDINAL method ,THROMBOLYTIC therapy - Abstract
Abstract: Objectives: A systematic review was performed to summarise outcomes of acute thrombosed popliteal artery aneurysms (PAAs) treated with thrombolysis or thrombectomy followed by bypass. Methods: A systematic review was conducted of data on acute thrombosed PAAs dated 1 January 1990 through 30 June 2008 using the Cochrane Library, MEDLINE and EMBASE databases. Primary endpoint was limb salvage; secondary endpoints were mortality and patency of the bypasses. Results: Eight prospective studies and 25 retrospective studies with 895 patients presenting with acute ischaemia were included. No randomised trials were included. The mortality rate after surgical repair was 3.2% (95% confidence interval (C.I.) 1.8–4.6). The amputation rate was 14.1% (95% C.I. 11.8–16.4). Thrombolysis before surgery did not result in a significant reduction of the number of amputations, compared with surgery (thrombectomy and bypass) alone. The mean primary patency rates of the bypasses at 1, 3 and 5 years were 79%, 77% and 74%, respectively, in the ‘thrombolysis’ group and 71% (P =0.026), 54% (P =0.164) and 45% (P =0.249) in the ‘thrombectomy’ group. No distinction could be made regarding secondary patency and limb-salvage rates between the groups owing to insufficient data. Conclusions: Preoperative and intra-operative thrombolyses result in a significant improvement in 1-year primary graft patency rates, but do not result in a significant reduction for amputations compared with surgery alone. [Copyright &y& Elsevier]
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- 2010
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12. Stapled Technique for Acute Thrombosed Hemorrhoids: A Randomized, Controlled Trial with Long-Term Results.
- Author
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Wong, J. C. H., Chung, C. C., Yau, K. K., Cheung, H. Y. S., Wong, D. C. T., Chan, O. C. Y., and Li, M. K. W.
- Abstract
This study was designed to compare stapled vs. conventional hemorrhoidectomy for patients with acute thrombosed hemorrhoids. Forty-one patients with acute thrombosed hemorrhoids were randomized into: 1) stapled hemorrhoidectomy (PPH group; n = 21), and 2) open hemorrhoidectomy (open group; n = 20). Emergency surgery was performed with perioperative data and complications were recorded. Patients were followed up by independent assessors to evaluate pain, recurrence, continence function, and satisfaction at regular intervals. The median follow-up for the PPH group and open group were 59 and 56 weeks, respectively. There was no significant difference in terms of the hospital stay, complication rate, and continence function; however, the mean pain intensity in the first postoperative week was significantly less in the PPH group (4.1 vs. 5.7, P = 0.02). Patients in the PPH group recovered significantly faster in terms of the time to become analgesic-free (4 vs. 8.5 days, P < 0.01), time to become pain-free (9 vs. 20.5 days, P = 0.01), resumption of work (7 vs. 12.5 days, P = 0.01), and time for complete wound healing (2 vs. 4 weeks, P < 0.01). On long-term follow-up, significantly fewer patients in the PPH group complained of recurrent symptoms (0 vs. 5, P = 0.02). The overall symptom improvement and patients’ satisfaction were significantly better in the PPH group (90 vs. 80 percent, P = 0.03 and +3 vs. +2, P < 0.01 respectively). Stapled hemorrhoidectomy is safe and effective for acute thrombosed hemorrhoids. Similar to elective stapled procedure, emergency stapled excision has greater short-term benefits compared with conventional excision: diminished pain, faster recovery, and earlier return to work. Long-term results and satisfaction were excellent. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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13. Giant pericallosal artery aneurysm: case report and review of the literature.
- Author
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Türe, U&gcaron;ur, Hiçdönmez, Tufan, Elmaci, Ilhan, and Peker, Selçuk
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INTRACRANIAL aneurysms ,NEUROSURGERY ,ANEURYSMS ,CEREBRAL angiography ,NEUROLOGICAL disorders ,DIAGNOSTIC imaging - Abstract
Pericallosal artery aneurysms comprise 5% of all intracranial saccular aneurysms and are usually small. Giant cerebral aneurysms mostly occur in major arteries. To date, 12 cases of giant pericallosal artery aneurysm have been reported in the literature. An unusual giant thrombosed pericallosal artery aneurysm is reported here. A 65-year-old female presented with headache and personality changes. Computed tomography, magnetic resonance imaging, and cerebral angiography revealed a right-sided giant thrombosed pericallosal artery aneurysm. The patient was operated via an anterior interhemispheric approach and the neck of the aneurysm was successfully clipped. The postoperative period was uneventful. This rare lesion is one of few cases presented in the literature in which neuroradiologic and neuropathologic evaluation was completely performed and the neck of the aneurysm was clipped. [ABSTRACT FROM AUTHOR]
- Published
- 2001
14. Ruptured partially thrombosed anterior inferior cerebellar artery aneurysms : two case reports and review of literature
- Author
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Kanamori, Fumiaki, Kawabata, Teppei, Muraoka, Shinsuke, Kojima, Takao, Watanabe, Tadashi, Hatano, Norikazu, and Seki, Yukio
- Subjects
anterior inferior cerebellar artery ,thrombosed ,cardiovascular system ,aneurysm ,revascularization ,cardiovascular diseases ,anastomosis - Abstract
Aneurysms arising from the distal anterior inferior cerebellar artery (AICA) are very rare. When the parent artery is an AICA−posterior inferior cerebellar artery (PICA) variant, occlusion of the artery, even distal to the meatal loop, leads to a significant area of cerebellar infarction. We report two cases of ruptured partially thrombosed distal AICA aneurysms. In both cases, the parent artery was an AICA−PICA variant. The aneurysms were clipped in one case and trapped following occipital artery (OA)−AICA anastomosis in another case. It is important to keep the OA as a donor artery for revascularization in the treatment of the AICA−PICA variant aneurysms, especially when the absence of intra-aneurysmal thrombus is not comfirmed preoperatively.
- Published
- 2016
15. Giant Posterior Inferior Cerebellar Artery Aneurysm Mimicking a Brainstem Tumor.
- Author
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Sangrador-Deitos MV, Rodríguez Hernández LA, Balcázar-Padrón JC, Ruiz-Treviño A, and Nathal E
- Abstract
Aneurysms from the vertebrobasilar system are rare, accounting for only 5%-10% of all intracranial aneurysms. The most common sites in which these lesions occur are the bifurcation of the basilar artery and the origin of the posterior inferior cerebellar artery (PICA). When the aneurysms present in the distal portion of the PICA, they represent from 0.5% to 6%. These aneurysms are called giant when they exceed 25 mm in diameter. We present a case of a 49-year-old male who presented with acute obstructive hydrocephalus, which required ventriculoperitoneal shunting and left hemispheric cerebellar syndrome. The magnetic resonance imaging study revealed an occupative mass located in the fourth ventricle, and diagnostic angiography showed a partially thrombosed giant saccular aneurysm in the posterior inferior cerebellar artery. He underwent surgical management via a lateral suboccipital approach. The aneurysm was remodeled and clipped successfully without complications, with an uneventful postoperative course. Although rare, PICA aneurysms should always be considered when posterior fossa syndrome occurs, including brainstem and cranial nerve compression symptoms. It can easily be misdiagnosed as a neoplastic lesion, especially when the aneurysm reaches big or giant size. Therefore, complete diagnostic studies, such as cerebral angiography, must be performed. Surgical clipping must be offered as the first line of treatment. It provides occlusion of the aneurysm and relieves compressive symptoms., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2022, Sangrador-Deitos et al.)
- Published
- 2022
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16. Combined Microsurgical, Endovascular, and Endoscopic Approach to the Treatment of a Giant Vertebrobasilar Aneurysm.
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Plitt AR, Patel AR, McDougall CM, Halderman AA, Barnett SL, and Welch BG
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- Adult, Female, Humans, Treatment Outcome, Endovascular Procedures methods, Intracranial Aneurysm surgery, Microsurgery methods, Neuroendoscopy methods, Vertebrobasilar Insufficiency surgery
- Abstract
Background: Dolichoectasia is defined as elongation and dilatation of a blood vessel. In the intracranial circulation, the basilar artery is affected in 80% of cases. These are challenging lesions with an aggressive natural history, and treatment carries a relatively high rate of morbidity and mortality. We describe a case of multimodal treatment including endovascular, open microsurgical, and endoscopic endonasal approach (EEA) for management., Objective: To describe the technical nuance of the addition of the EEA for management of posterior circulation dolichoectasia., Methods: A 44-yr-old Hispanic woman with a 2-mo history of progressive headaches, gait disturbance, and lower cranial nerve dysfunction presented with acute neurologic decline. MRI demonstrated a dolichoectatic vertebrobasilar system with a giant 4.5-cm fusiform basilar aneurysm., Results: She underwent concomitant endovascular bilateral vertebral artery sacrifice with suction decompression and trapping by clip ligation distal to the lesion. Postoperatively, she developed symptomatic pontine compression. She was then taken for a transclival EEA for intra-aneurysmal thrombectomy. Thereafter, she made a significant functional recovery., Conclusion: The addition of endoscopic reconstruction to the treatment of a dolichoectatic basilar aneurysm is an operative nuance that can be employed in treating these highly morbid lesions. This case describing a multimodal treatment paradigm including EEA reconstruction can serve as an example for the future of treatment select cases of dolichoectasia of the vertebrobasilar complex., (Copyright © 2018 by the Congress of Neurological Surgeons.)
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- 2019
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17. Unusual Cause for Abdominal Pain in Cirrhosis : Thrombosed Intrahepatic Portal Vein Aneurysms
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Upasana Ranga, Senthil Kumar Aiyappan, and Saveetha Veeraiyan
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medicine.medical_specialty ,Abdominal pain ,Cirrhosis ,portal vein aneurysms ,Clinical Biochemistry ,Portal venous system ,lcsh:Medicine ,Chronic liver disease ,thrombosed ,Aneurysm ,medicine ,cardiovascular diseases ,mri ,Internal Medicine Section ,medicine.diagnostic_test ,business.industry ,cirrhosis ,lcsh:R ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Thrombosis ,Surgery ,cardiovascular system ,Portal hypertension ,Radiology ,medicine.symptom ,business ,ct - Abstract
Portal venous system aneurysm is a rare condition with very few reported cases in English literature. With the increasing availability of advanced imaging modalities like Doppler ultrasound, computed tomography and magnetic resonance imaging, portal venous system aneurysms are being increasingly reported. Here, we report a rare case of multiple intrahepatic portal venous system aneurysms complicated by thrombosis in a young patient with chronic liver disease and portal hypertension.
- Published
- 2014
- Full Text
- View/download PDF
18. Unusual Cause for Abdominal Pain in Cirrhosis : Thrombosed Intrahepatic Portal Vein Aneurysms.
- Author
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AIYAPPAN, SENTHIL KUMAR, RANGA, UPASANA, and VEERAIYAN, SAVEETHA
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TREATMENT of abdominal pain ,CIRRHOSIS of the liver ,PORTAL vein diseases ,THROMBOSIS ,COMPUTED tomography ,PROGNOSIS - Abstract
Portal venous system aneurysm is a rare condition with very few reported cases in English literature. With the increasing availability of advanced imaging modalities like Doppler ultrasound, computed tomography and magnetic resonance imaging, portal venous system aneurysms are being increasingly reported. Here, we report a rare case of multiple intrahepatic portal venous system aneurysms complicated by thrombosis in a young patient with chronic liver disease and portal hypertension. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
19. Disappearance of a basilar tip aneurysm after wrapping.
- Author
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Callari, G. and Marks, S. M.
- Subjects
- *
INTRACRANIAL aneurysms , *ANGIOGRAPHY , *ANEURYSMS - Abstract
A young woman underwent craniotomy and wrapping of a ruptured basilar tip aneurysm on day 6 following a subarachnoid hemorrhage. An angiogram 3 years later showed that the aneurysm had disappeared.We suggest the possible reasons. [ABSTRACT FROM AUTHOR]
- Published
- 2000
- Full Text
- View/download PDF
20. Endovascular treatment of a spinal dural arteriovenous malformation (DAVF).
- Author
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Agarwal V, Zomorodi A, Jabbour P, Chalouhi N, Tjoumakaris S, Babu R, Back A, and Gonzalez LF
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- Central Nervous System Vascular Malformations complications, Drug Combinations, Embolization, Therapeutic instrumentation, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Male, Middle Aged, Polyvinyls, Spinal Cord Diseases complications, Tantalum, Central Nervous System Vascular Malformations surgery, Embolization, Therapeutic methods, Spinal Cord Diseases surgery
- Abstract
We present a case of a patient with rapid loss of motor strength in his lower extremities. He became bedridden with bowel and bladder incontinence, and developed saddle anesthesia. MRI of the lumbar spine showed edema in the conus medullaris and multiple flow voids within the spinal canal. A spinal angiogram showed a dorsal Type I spinal AVF. This was treated successfully with Onyx 18 (eV3, Irvine, CA). The patient showed rapid post-procedure improvement, and at discharge from the hospital to a rehabilitation center he was fully ambulatory. At 3-year follow-up, the patient was found to ambulate without difficulty. He also had improved saddle anesthesia, and he was voiding spontaneously. There was no evidence of flow voids on repeat MRI of the lumbar spine. The video can be found here: http://youtu.be/SDYNIGNQIW8 .
- Published
- 2014
- Full Text
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21. Clinical Outcome of Acute Leg Ischaemia Due to Thrombosed Popliteal Artery Aneurysm: Systematic Review of 895 Cases
- Author
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J.P.P.M. de Vries, F.L. Moll, Johannes C. Kelder, A.M. Schrijver, and Rogier H.J. Kropman
- Subjects
Reoperation ,medicine.medical_specialty ,Time Factors ,Popliteal artery aneurysm ,medicine.medical_treatment ,Ischemia ,Cochrane Library ,Ischaemia ,Amputation, Surgical ,medicine.artery ,medicine ,Vascular Patency ,Humans ,Popliteal Artery ,Thrombolytic Therapy ,Prospective cohort study ,Thrombectomy ,Medicine(all) ,business.industry ,Patient Selection ,Thrombosed ,Retrospective cohort study ,Thrombosis ,Thrombolysis ,Vascular surgery ,Limb Salvage ,medicine.disease ,Aneurysm ,Combined Modality Therapy ,Popliteal artery ,Surgery ,Treatment Outcome ,Amputation ,Lower Extremity ,Acute Disease ,Cardiology and Cardiovascular Medicine ,business ,Vascular Surgical Procedures - Abstract
Objectives A systematic review was performed to summarise outcomes of acute thrombosed popliteal artery aneurysms (PAAs) treated with thrombolysis or thrombectomy followed by bypass. Methods A systematic review was conducted of data on acute thrombosed PAAs dated 1 January 1990 through 30 June 2008 using the Cochrane Library, MEDLINE and EMBASE databases. Primary endpoint was limb salvage; secondary endpoints were mortality and patency of the bypasses. Results Eight prospective studies and 25 retrospective studies with 895 patients presenting with acute ischaemia were included. No randomised trials were included. The mortality rate after surgical repair was 3.2% (95% confidence interval (C.I.) 1.8–4.6). The amputation rate was 14.1% (95% C.I. 11.8–16.4). Thrombolysis before surgery did not result in a significant reduction of the number of amputations, compared with surgery (thrombectomy and bypass) alone. The mean primary patency rates of the bypasses at 1, 3 and 5 years were 79%, 77% and 74%, respectively, in the ‘thrombolysis’ group and 71% ( P = 0.026), 54% ( P = 0.164) and 45% ( P = 0.249) in the ‘thrombectomy’ group. No distinction could be made regarding secondary patency and limb-salvage rates between the groups owing to insufficient data. Conclusions Preoperative and intra-operative thrombolyses result in a significant improvement in 1-year primary graft patency rates, but do not result in a significant reduction for amputations compared with surgery alone.
- Full Text
- View/download PDF
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