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3D reconstruction has raised much interest in the field of CSAR. However, three dimensional imaging results with single pass CSAR data reveals that the 3D resolution of the system is poor for anisotropic scatterers. According to the imaging mechanism of CSAR, different targets located on the same iso-range line in the zero doppler plane fall into the same cell while for the same target point, imaging point will fall into the different positions at different aspect angles. In this paper, we proposed a method for 3D point cloud reconstruction using projections on 2D sub-aperture images. The target and background in the sub-aperture images are separated and binarized. For a projection point of target, given a series of offsets, the projection point will be mapped inversely to the 3D mesh along the iso-range line. We can obtain candidate points of the target. The intersection of iso-range lines can be regarded as voting process. For a candidate, the more times of intersection, the higher the number of votes, and the candidate point will be reserved. This fully excavates the information contained in the angle dimension of CSAR. The proposed approach is verified by the Gotcha Volumetric SAR Data Set.

Purpose: X-ray fluorescence (XRF) is a promising technique with sufficient specificity and sensitivity for identifying and quantifying features in small samples containing high atomic number (Z) materials such as iodine, gadolinium, and gold. In this study, the feasibility of applying XRF to early breast cancer diagnosis and treatment is studied using a novel approach for three-dimensional (3D) x-ray fluorescence mapping (XFM) of gold nanoparticle (GNP)-loaded objects in a physical phantom at the technical level. Methods: All the theoretical analysis and experiments are conducted under the condition of using x-ray pencil beam and a compactly integrated x-ray spectrometer. The penetrability of the fluorescence x-rays from GNPs is first investigated by adopting a combination of BR12 with 70 mm/50 mm in thickness on the excitation/emission path to mimic the possible position of tumor gold in vivo. Then, a physical phantom made of BR12 is designed to translate in 3D space with three precise linear stages and subsequently the step by step XFM scanning is performed. The experimental technique named as background subtraction is applied to isolate the gold fluorescence from each spectrum obtained by the spectrometer. Afterwards, the attenuations of both the incident primary x-ray beam with energies beyond the gold K-edge energy (80.725 keV) and the isolated gold Ka fluorescence x-rays (65.99 -69.80 keV) acquired after background subtraction are well calibrated, and finally the unattenuated Ka fluorescence counts are used to realize mapping reconstruction and to describe the linear relationship between gold fluorescence counts and corresponding concentration of gold solutions. Results: The penetration results show that the gold Ka fluorescence x-rays have sufficient penetrability for this phantom study, and the reconstructed mapping results indicate that both the spatial distribution and relative concentration of GNPs within the designed BR12 phantom can be well identified and quantified. Conclusions: Although the XFM method in this investigation is still studied at the technical level and is not yet practical for routine in vivo mapping tasks with GNPs, the current penetrability measurements and phantom study strongly suggest the feasibility to establish and develop a 3D XFM system. [ABSTRACT FROM AUTHOR]

3D reconstruction has raised much interest in the field of CSAR. However, three dimensional imaging results with single pass CSAR data reveals that the 3D resolution of the system is poor for anisotropic scatterers. According to the imaging mechanism of CSAR, different targets located on the same iso-range line in the zero doppler plane fall into the same cell while for the same target point, imaging point will fall into the different positions at different aspect angles. In this paper, we proposed a method for 3D point cloud reconstruction using projections on 2D sub-aperture images. The target and background in the sub-aperture images are separated and binarized. For a projection point of target, given a series of offsets, the projection point will be mapped inversely to the 3D mesh along the iso-range line. We can obtain candidate points of the target. The intersection of iso-range lines can be regarded as voting process. For a candidate, the more times of intersection, the higher the number of votes, and the candidate point will be reserved. This fully excavates the information contained in the angle dimension of CSAR. The proposed approach is verified by the Gotcha Volumetric SAR Data Set. [ABSTRACT FROM AUTHOR]