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Background and Objectives: This study is a retrospective analysis aimed at understanding the incidence and risk factors of proximal junctional kyphosis (PJK) following long-instrumented spinal fusion from L1 to the sacrum in patients with mild to moderate sagittal imbalance. Materials and Methods: It recruited consecutive patients undergoing instrumented fusion from L1 to the sacrum for degenerative lumbar disease between June 2006 and November 2019 in a single institution. The patients' preoperative clinical data, muscle status at T12-L1 on magnetic resonance images, and sagittal spinopelvic parameters were analyzed. Univariate analysis was used to compare clinical and radiographic data between PJK and non-PJK patients. Logistic regression analysis was used to investigate the independent risk factors for PJK. Results: A total of 56 patients were included in this study. The mean age at surgery was 67.3 years and mean follow-up period was 37.3 months. In total, 10 were male and 46 were female. PJK developed in 23 (41.1%) out of 56; of these patients, 20 (87.0%) developed PJK within 1 year postoperatively. In the univariate analysis between PJK and non-PJK patients, the PJK group showed more frequent osteoporosis, lower body mass index, smaller cross-sectional area (CSA) and more fat infiltration (FI) in erector spinae muscle at T12-L1 and larger preoperative TLK and PT with statistical significance (p < 0.05). In the logistic regression analysis, severe (>50%) FI in erector spinae muscle (OR = 43.60, CI 4.10–463.06, R2N = 0.730, p = 0.002) and osteoporosis (OR = 20.49, CI 1.58–264.99, R2N = 0.730, p = 0.021) were statistically significant. Conclusions: Preexisting severe (>50%) fat infiltration in the erector spinae muscle and osteoporosis were independent risk factors associated with PJK following instrumented fusion from L1 to the sacrum, but age was not a risk factor. [ABSTRACT FROM AUTHOR]

Objective: To analyze various transpedicular (TP) fixation options for the thoracolumbar junction (TLJ) under rotational loads. Methods: A finite element model of the thoracolumbar spine was generated as part of a study. The model includes vertebrae Th9-Th11 and L2-L5 but excludes Th12 and L1. The model also integrates metallic structural elements, such as a vertebral body replacement (VBR) implant (interbody cage) and a TP system. We modeled the result of decompressive-stabilizing surgery for type C vertebral injuries (according to the classification scheme proposed by F. Magerl et al, 1994). The study analyzes four variants of TP fixation with different screw lengths and the influence of the presence or absence of transverse reinforcements. Results: It was found that during rotational loading, the maximum stress in bone structures occurs at the contact surface between the VBRs and the endplates of both adjacent vertebrae to the removed ones. In metallic hardware, the highest stress is observed on the interbody cage and in the TP screws installed in the Th10 and Th11 vertebral bodies. A comparison of different stabilization options reveals that the TP system with short monocortical screws and without transverse reinforcements provides moderate levels of stress. The use of bicortical screws without crosslinks results in a significant increase in stress, especially at the contact surface in the vertebral endplates and the intervertebral support device. On the other hand, the use of transverse reinforcements with short screws reduces stress, providing an optimal stabilization option. However, bicortical screws with crosslinks did not show significant benefits. Conclusion: Upon scrutinizing the biomechanical efficiency of different TP fixation methods, it has been determined that utilizing a TP system equipped with monocortical screws and two crosslinks results in the most even stress distribution caused by the rotational load.

Indirect decompression of the spinal canal through ligamentotaxis is one of the methods for remodeling the spinal canal in traumatic stenosis. Objective: To evaluate the effectiveness of indirect de-compression of the spinal canal for different morphological types of burst fractures of vertebral bodies at the thoracolumbar junction. Methods. A preoperative and postoperative analysis of computed tomography scans was performed on 59 patients who were treated at the«Romodanov Neurosurgery Institute, National Academy of Medical Sciences of Ukraine» for burst fractures at the thoraco-lumbar junction. The criterion for the effectiveness of indirect de-compression was the area of the spinal canal, measured at the level of injury in the zone of maximum compression. The grading of burst fractures was performed using the classification by F. Magerl et al. (1994). Results. In the preoperative period, the median degree of stenosis in the group of patients was 43.47 % (95 % confidence interval (CI): 37.53-46.22 %). For damage type A3.1, it was 36.9 % (95 % CI: 28.1-40.5 %>), for type A3.2 -- 46.1 % (95 % CI: 32.1-54.5 %), and for type A3.3 -- 47.6 % (95 % CI: 37.5-56.5 %). After surgical treatment, the degree of stenosis decreased by 20.14 % (95 % CI: 15.93-21.56 %). For type A3.1, the effectiveness was 20.1 % (95 % CI: 9.5-22.7 %), for type A3.2 --15.2 % (95 % CI: 7.51-17.3 %>), and for type A3.3 -- 21.7 % (95 % CI: 20.8-26.4 %). The difference between types A3.2 andA3.3 was statistically significant (p = 0.0018). It was found that indirect decompression is most effective with higher degrees of stenosis. For Grade I by D. Wolter (1988), the canal expansion achieved was 7.07 % (95 % CI: 5.69-8.65 %), for Grade II -- 21.6 % (95 % CI: 20.4-22.7 %>), and for Grade III -- 30.3 % (95 % CI: 27.0-33.6 %). Conclusions. Closed remodeling of the spinal canal with transpedicular fixation and the effect of ligamentotaxis is an effective method for correcting traumatic spinal canal stenosis at the thoracolumbar junction. The effectiveness of the technique is determined by many factors, including the type of burst fracture, the initial degree of stenosis, and the level of injury. [ABSTRACT FROM AUTHOR]

Several studies have investigated the mechanical behavior of the thoracolumbar spine. However, finding an accurate reference for the normal functional local alignment and segmental motion (SM) at the thoracolumbar junction (TLJ) is challenging. Therefore, this study aimed to assess age- and sex-related changes and differences in local alignment and SM at the TLJ. The study recruited healthy subjects aged 20 to 79 without complaints of back pain. Healthy subjects (60 males and 60 females) with appropriate imaging results were enrolled in the study. The subjects were divided into age groups (20–29, 30–39, 40–49, 50–59, 60–69, and 70–79 years); each group included 10 subjects of each sex. The SM at the TLJ was small but noticeable, and the motion gradually increased toward the lower level of the TLJ, closer to the lumbar region. No significant differences were observed between male and female subjects in any SM measurements at the TLJ. The SM at the TLJ gradually decreased with age, while local kyphosis of TLJ progressed. The results also showed that the thoracolumbar slope value did not change with age and remained at a mean of −12.8 ± 7.2° (P = 0.893). This study's results provide valuable guidance for appropriate surgical planning and rehabilitation of patients with spinal diseases or trauma. Furthermore, the results can be the basis for categorizing accurate criteria to evaluate the degree of disability after treatment. [ABSTRACT FROM AUTHOR]

The thoracolumbar junction is the most vulnerable to traumatic injuries, with over 65 % of injuries to the thoracolumbar spine occurring in this region. Objective: To examine the stress-strain state of the thoracolumbar spine model with a burst fracture of the Th12 vertebra under various transpedicular fixation options influenced by rotational loading. Materials and methods: A mathematical finite-element model of the human thoracolumbar spine was developed, including a burst fracture of the Th12 vertebra and a transpedicular stabilization system containing eight screws implanted in the Th10, Th11, L1, and L2 vertebrae. Four variants of transpedicular fixation were modelled using short and long screws passing through the anterior surface of the vertebra, with and without two crosslinks. Results: The analysis showed sufficiently high loading values for both the bone structures of the models and the elements of the metal construct. The maximum stress level in the body of the damaged vertebra was 33.2, 26.7, 30.1, and 24.2 MPa, respectively, for models with monocortical screws without crosslinks, bicortical screws without crosslinks, monocortical screws with crosslinks, and bicortical screws with crosslinks. High values were also recorded for the vertebrae adjacent to the damaged one: 13.0, 8.4, 10.9, and 7.1 MPa for the L1 vertebra and 10.2, 8.9, 7.1, and 6.2 MPa for the Th11 vertebra in the respective models. The stress on the supporting rods was registered at 582.0, 512.5, 512.6, and 452.7 MPa respectively. Conclusion: The conducted analysis demonstrated that under rotational loading, the model with monocortical screws without crosslinks shows the highest peak loads at control points, whereas the model with bicortical screws and crosslinks shows the minimum. Meanwhile, models with short screws and crosslinks and long screws without crosslinks exhibit comparable results. [ABSTRACT FROM AUTHOR]

Background and Objectives: This study is a retrospective analysis aimed at understanding the incidence and risk factors of proximal junctional kyphosis (PJK) following long-instrumented spinal fusion from L1 to the sacrum in patients with mild to moderate sagittal imbalance. Materials and Methods: It recruited consecutive patients undergoing instrumented fusion from L1 to the sacrum for degenerative lumbar disease between June 2006 and November 2019 in a single institution. The patients’ preoperative clinical data, muscle status at T12-L1 on magnetic resonance images, and sagittal spinopelvic parameters were analyzed. Univariate analysis was used to compare clinical and radiographic data between PJK and non-PJK patients. Logistic regression analysis was used to investigate the independent risk factors for PJK. Results: A total of 56 patients were included in this study. The mean age at surgery was 67.3 years and mean follow-up period was 37.3 months. In total, 10 were male and 46 were female. PJK developed in 23 (41.1%) out of 56; of these patients, 20 (87.0%) developed PJK within 1 year postoperatively. In the univariate analysis between PJK and non-PJK patients, the PJK group showed more frequent osteoporosis, lower body mass index, smaller cross-sectional area (CSA) and more fat infiltration (FI) in erector spinae muscle at T12-L1 and larger preoperative TLK and PT with statistical significance (p < 0.05). In the logistic regression analysis, severe (>50%) FI in erector spinae muscle (OR = 43.60, CI 4.10–463.06, R2N = 0.730, p = 0.002) and osteoporosis (OR = 20.49, CI 1.58–264.99, R2N = 0.730, p = 0.021) were statistically significant. Conclusions: Preexisting severe (>50%) fat infiltration in the erector spinae muscle and osteoporosis were independent risk factors associated with PJK following instrumented fusion from L1 to the sacrum, but age was not a risk factor.

Study Design.: Retrospective study of a multicenter prospective database. Objective.: The objective of this study was to determine the organization and correlations between different spinal segments according to pelvic incidence (PI) and age. Summary of Background Data.: When planning surgery for the correction of adult spinal deformities, considering lumbar lordosis (LL) as a uniform segment is an approximation that can lead to planning errors. Materials and Methods.: Radiographs of 1540 subjects were analyzed and divided into three PI groups: low <45, intermediate 45 to 60, high >60, and stratified by age (<45, 45–70, and >70 yr). The different segments of L1–L4 proximal lumbar lordosis (PLL), L4–S1 distal lumbar lordosis (DLL), and T10–L1 thoracolumbar junction (TLJ) were analyzed. Results.: The mean age was 53.5 years (SD=17, minimum=20, maximum=93). There was a significant correlation between thoracic kyphosis T5–T12 and TLJ segment T10–L1 (r =0.581, P <0.001). Only the L1–L4 PLL segment correlated with PI (r =0.47, P <0.001). The T10–L1 TLJ segment was constant regardless of age or PI groups considered (mean=−8, SD=9). PLL did not vary with aging but differed according to PI. The DLL showed significant differences between age and PI groups but without a significant correlation between PI and DLL. Conclusions.: Pelvic morphology is known to determine the curvatures of the spine, however, the distribution of LL is not homogeneous. Our study provided a normative value reference and showed that T10–L1 is constant regardless of age or PI. Level of Evidence.: III. [ABSTRACT FROM AUTHOR]

Thoracolumbar disc herniation (TLDH) is a rare disorder with unique characteristics that can result in undesirable surgical outcomes after traditional discectomy. In view of the widespread use of transforaminal endoscopic discectomy for lower lumbar disc herniation, we investigated treatment of TLDH by this procedure. The purpose of this study was to evaluate the clinical efficacy of transforaminal endoscopic discectomy for treating TLDH and share our technical experience. We retrospectively evaluated the clinical data of 19 patients who had undergone transforaminal endoscopic discectomy for TLDH in our institution between April 2018 and July 2021. Operation time, follow-up time, blood loss, postoperative hospital stay, visual analog scale scores for low-back and leg pain, and Japanese Orthopedic Association (JOA) scores were evaluated. The differences between preoperative and postoperative JOA and visual analog scale scores were significant (P < 0.05). According to the JOA scores, 14 of the 19 patients had excellent improvement, 3 had good improvement, and 2 had fair improvement; thus, the rate of satisfactory improvement was 89.5%. Operation time, blood loss, postoperative hospital stay, and surgical outcomes were favorable. Transforaminal endoscopic discectomy is an ideal surgical procedure for treating TLDH. [ABSTRACT FROM AUTHOR]

Study design: In vitro biomechanical study investigating the coupled motions of the whole normative human thoracic spine (TS) and lumbar spine (LS) with rib cage. Objective: To quantify the region‐specific coupled motion patterns and magnitudes of the TS, thoracolumbar junction (TLJ), and LS simultaneously. Background: Studying spinal coupled motions is important in understanding the development of complex spinal deformities and providing data for validating computational models. However, coupled motion patterns reported in vitro are controversial, and no quantitative data on region‐specific coupled motions of the whole human TS and LS are available. Methods: Pure, unconstrained bending moments of 8 Nm were applied to seven fresh‐frozen human cadaveric TS and LS specimens (mean age: 70.3 ± 11.3 years) with rib cages to elicit flexion‐extension (FE), lateral bending (LB), and axial rotation (AR). During each primary motion, region‐specific rotational range of motion (ROM) data were captured. Results: No statistically significant, consistent coupled motion patterns were observed during primary FE. During primary LB, there was significant (p < 0.05) ipsilateral AR in the TS and a general pattern of contralateral coupled AR in the TLJ and LS. There was also a tendency for the TS to extend and the LS to flex. During primary AR, significant coupled LB was ipsilateral in the TS and contralateral in both the TLJ and LS. Significant coupled flexion in the LS was also observed. Coupled LB and AR ROMs were not significantly different between the TS and LS or from one another. Conclusions: The findings support evidence of consistent coupled motion patterns of the TS and LS during LB and AR. These novel data may serve as reference for computational model validations and future in vitro studies investigating spinal deformities and implants. [ABSTRACT FROM AUTHOR]

Objective Second fractures at the cemented vertebrae (SFCV) are often seen after percutaneous kyphoplasty, especially at the thoracolumbar junction. Our study aimed to develop and validate a preoperative clinical prediction model for predicting SFCV. Methods A cohort of 224 patients with single-level thoracolumbar osteoporotic vertebral fractures (T11–L2) from 3 medical centers was analyzed between January 2017 and June 2020 to derive a preoperative clinical prediction model for SFCV. Backward-stepwise selection was used to select preoperative predictors. We assigned a score to each selected variable and developed the SFCV scoring system. Internal validation and calibration were conducted for the SFCV score. Results Among the 224 patients included, 58 had postoperative SFCV (25.9%). The following preoperative measures on multivariable analysis were summarized in the 5-point SFCV score: bone mineral density (≤–3.05), serum 25-hydroxy vitamin D3 (≤17.55 ng/mL), standardized signal intensity of fractured vertebra on T1-weighted images (≤59.52%), C7–S1 sagittal vertical axis (≥3.25 cm), and intravertebral cleft. Internal validation showed a corrected area under the curve of 0.794. A cutoff of ≤1 point was chosen to classify a low risk of SFCV, for which only 6 of 100 patients (6%) had SFCV. A cutoff of ≥4 points was chosen to classify a high risk of SFCV, for which 28 of 41 (68.3%) had SFCV. Conclusion The SFCV score was found to be a simple preoperative method for identification of patients at low and high risk of postoperative SFCV. This model could be applied to individual patients and aid in the decision-making before percutaneous kyphoplasty. [ABSTRACT FROM AUTHOR]

Objective: The purpose of this study was to evaluate the long-term clinical, functional, and radiological outcomes of operative and nonoperative treated patients with thoracolumbar fracture. Materials and Methods: Between January 2016 and December 2021, data of patients hospitalized in our clinic due to thoracolumbar (T11-L2) fracture were collected and analyzed. Results: Two hundred eighteen patients met the inclusion criteria. One hundred thirty eight patients (63.3%) were operated and 80 patients (36.7%) were treated with nonsurgical methods. The duration of follow-up ranged from 13 to 82 months. There was a significant difference between the first admission oswestry disability index (ODI) and visual analog scale (VAS) and the final visit ODI and VAS when both operative and nonoperative treatment patients were evaluated separately and when evaluated together. The scores at the last control visit were significantly lower than the initial scores (p<0.001). When the fracture level was compared with the ODI and VAS, a significant difference was observed in the ODI score at the first admission (p=0.03). The ODI score at first admission was highest in patients with T11 fractures and lowest in patients with L2 fractures. There was a significant correlation between the "Anterior Vertebral Body Compression Percentage %" and four-vessel cerebral angiography (p<0.001). Conclusion: Patients with high vertebral depression and low functionality were operated, and regardless of the treatment protocol, pain decreased and functionality increased in all patients. The height of the vertebral corpus affects the angle of kyphosis, and surgical management is needed for the kyphotic deformity. Patients with high thoracolumbar fractures were more painful. [ABSTRACT FROM AUTHOR]

According to modern concepts, one of the basic criteria for the stability of the spinal motion segment in case of its traumatic damage is the integrity of the posterior ligamentous complex (PLC). Regarding the thoracolumbar junction (TLJ) as a zone that is most vulnerable to traumatic injuries, the Thoracolumbar Injury Classification and Severity Score and the clinically oriented AO Spine Thoracolumbar Spine Injury Classification System are used in determining therapeutic approaches in which the state of the thoracic spine is one of three key parameters. The term PLC was first proposed in 1963 by F.W. Holdsworth. However, only the widespread introduction of magnetic resonance imaging into clinical practice made it possible to fully reveal the informativeness of the specified parameter. The complex includes the interspinous, supraspinous ligaments, ligamentum flavum and facet joint capsule. The purpose of the review is to organize modern ideas about the morphology, biomechanical features, clinical significance, and diagnostic possibilities of detecting damage to the PLC in traumatic injuries of the TLJ area. In the first part, the morphological and biomechanical features of the PLC of the TLJ zone are considered in detail. When describing the morphology of some ligaments, the main attention is paid to their length, fixation zones, and certain layers, if such are distinguished. In addition, the relative anatomical location of the considered structures was taken into account. Histological features are indicated only in terms of their biomechanical significance. The analysis of literature data made it possible to organize the data characterizing the biomechanical parameters of each ligament of the PLC for each spinal motion segment of the area under consideration. Stiffness indicators, breaking force, fracture energy, strength and deformation limits, maximum deformation and elastic modulus were taken into account. The features of the load-deformation curve of the TLJ ligaments and methods of calculating the nonlinear change in the stiffness of each ligament of the PLC within the limits of physiological loads are considered. The phenomenon of preload and its clinical significance are described. Some aspects of the interaction between the elements of the passive stabilization system under different load patterns are considered. The data presented in the first part of the review can be useful for a general understanding of the principles of biomechanics of the spinal motion segment and may be used in the construction of highly detailed computer models. [ABSTRACT FROM AUTHOR]

Abstract Objectives The extension of diffuse idiopathic skeletal hyperostosis (DISH) from the low thoracic spine to the lumbar spine result in adjustment of spinal sagittal alignment in surgical patients. The aim of this study was to investigate changes in sagittal alignment and back pain in the thoracolumbar spine in nonsurgical DISH and control participants selected from a radiological database. Methods Participants in the DISH and the control group were selected by searching for “DISH or degenerative changes in the thoracic spine” in the radiology database of Taizhou Hospital between 2018 and 2021 using Resnick and Niwayama’s criteria. The subjects with spinal tumors, previous spinal surgery, vertebral fractures, inflammatory diseases, poor-quality radiographs, or loss of follow-up were excluded. Demographic and clinical characteristics were recorded retrospectively via the hospital information system and telephone follow-up. Segmental disc angles (SDAs), lumbar lordosis (LL), and bridge scores were analyzed using images of three-dimensional CT. Results The final participants consisted of 51 individuals with DISH (DISH group) and 102 individuals without DISH (control group). Depending on the presence of thoracolumbar pain, the DISH group was divided into the DISH group with thoracolumbar pain (DISH+Pain) and the DISH group without thoracolumbar pain (DISH-Pain). The LL and SDAs of T11-T12 and T12-L1 were significantly greater in the DISH group than in the control group. In addition, the SDA of L1-L2 was significantly smaller in the DISH+Pain group than in the DISH-Pain group, whereas there was no significant difference in lumbar lordosis between the DISH+Pain group and the DISH-Pain group. The bridge scores in DISH+Pain group was larger in T10-T11 (p = 0.01) and L1-L2 (p

Abstract Background Fixed severe hyperkyphotic deformities spread over more than five vertebral levels represent a therapeutic challenge, especially when the deformity apex is located at the thoraco-lumbar junction, thus requiring a huge amount of correction. The aim of this article is to describe an innovative all-posterior corrective technique based on multilevel non-contiguous thoracic pedicle subtraction ostoeotomy (PSO). Materials and methods A retrospective review of three patients with fixed severe thoracic hyperkyphosis (a deformity angle of over 70°) with a thoraco-lumbar apex (between T11 and L1) treated by simultaneous two-level thoracic PSO and thoraco-lumbar posterior fusion was performed. Radiographic and clinical records were evaluated pre-operatively, post-operatively and at last follow-up (after a minimum of 2 years). Each variable was presented as mean ± SD (standard deviation). Statistical analyses were performed using paired t-tests (P value

Study Design.: Prospective randomized controlled trial. Objective.: To clarify whether percutaneous curved vertebroplasty (PCVP) is superior to conventional unipedicular approach vertebroplasty (UVP) in patients with acute osteoporotic vertebral compression fractures (OVCFs). Summary of Background Data.: Unilateral curved vertebroplasty devices were designed and applied to provide better control of cement placement, which may be superior to traditional UVP for the treatment of acute OVCFs. Materials and Methods.: Patients with single-level OVCFs of <6 weeks duration and visual analog scale (VAS) of back pain 5 or more were randomly allocated to undergo PCVP or UVP and were followed up for 1 year. The primary outcome was overall VAS scores for back pain during 12 months of follow-up. The secondary outcomes were scores on the Oswestry disability index at each postprocedure clinic visit. Radiographic (cement distribution) and surgical data (operation time, fluoroscopy frequency, and cement volume) were assessed. Complications and adverse events were recorded. Results.: No statistical difference was found between the PCVP and UVP groups with respect to VAS and Oswestry disability index scores at any follow-up time point. Operative time, fluoroscopy frequency, and cement leakage were similar in both groups, while the PCVP techniques had a larger injection of polymethylmethacrylate (5.5 ± 1.4 vs. 4.2 ± 1.0 mL) and a greater dispersion pattern of cement (P < 0.001). Post hoc observations found that the analgesic effect was positively correlated with the symmetry of bone cement distribution, but not with the surgical method. Two serious adverse events occurred in the vertebroplasty group: one stress ulcer and one allergic reaction. Conclusions.: Although PCVP achieved more symmetrical cement distribution, which seemed to be associated with a greater analgesic effect, PCVP did not result in significantly greater pain relief than a UVP in the 12 months after treatment. [ABSTRACT FROM AUTHOR]

Fractures at the thoracolumbar junction are the most common traumatic spinal injuries. Advances in instrumentation for vertebral body replacement have significantly improved surgical techniques. However, the biomechanical characteristics of stabilizing surgeries have been insufficiently studied. Objective. To investigate the stress-strain state (SSS) of a mathematical finite element model of the human thoracolumbar spine during trunk backward bending after ThXII vertebra resection, considering different transpedicular fixation options. Methods. A mathematical finite element model of the human thoracolumbar spine -- ThIX-LV vertebrae -- was developed. The ThXII vertebra was removed, and an interbody support and transpedicular system with 8 screws were implanted to simulate the post-surgical state after a ThXII burst fracture with wide laminectomy, facetectomy, and corpectomy. The influence of transpedicular screw length and the presence of cross-links on the SSS of the model was examined. Results. The use of bicortical screws reduced stress levels in the bone elements of the model, except in the regions around the screws in the lumbar vertebrae, when compared to short screws. Installing cross-links decreased stress levels at all control points compared to models without cross-links. Specifically, in the presence of cross-links, the SSS values at the entry points of the short screws into the vertebral bodies of ThX, ThXI, LI, and LII were 2.3, 1.8, 1.2, and 5.0MPa, respectively, compared to 2.7, 2.0, 1.5, and 6.1 MPa in the models without cross-links. In the case of bicortical screws without cross-links, the stress values at the screw entry points into the pedicles of the corresponding vertebrae were 2.9, 1.5, 8.2, and 11.2 MPa, respectively, compared to 2.7, 1.5, 7.5, and 10.2 MPa in the models with cross-links. Conclusions. When the trunk is tilted backward, the use of cross-links reduces stress levels at all control points in the models, regardless of the screw length used. Bicortical transpedicular screws increase stress levels on the screws themselves and in the lumbar vertebral bodies surrounding them. [ABSTRACT FROM AUTHOR]

Background. The area of the thoracolumbar junction is characterized by a significant load that dictates increased requirements to stabilization, which should not only provide a reliable and rigid fixation, but also ensure the maximum uniform distribution of the load on all elements of both the metal structure and the bone tissue to exclude the failure of fixation in the long run. Purpose of the study is to investigate the influence of the transpedicular screw length and the presence of crosslinks on the load distribution during surgical resection of one vertebra from the thoracolumbar junction under the influence of axial compressive load. Materials and methods. We analyzed mathematical finite-element model of the part of thoracolumbar spine (Th9-L5), where the Th12 vertebra was removed and replaced by an interbody implant with additional fixation by a transpedicular system. Four variants of transpedicular fixation were modeled using short and long screws, as well as with and without two crosslinks. The stress-strain state of the models was studied under the influence of a vertical compressive distributed load of 350 N. Results. When using short screws and in the absence of crosslinks, the maximum stresses in the Th10, Th11, L1, and L2 vertebrae are 7.2, 5.3, 4.2, and 14.3 MPa, respectively, when using long screws without crosslinks — 6.5, 4.6, 3.8 and 13.5 MPa. The model with short screws and crosslinks shows 7.1, 4.4, 3.9 and 14.0 MPa, while the application of long screws with crosslinks is 6.3, 4.5, 3.5 and 13.2 MPa, respectively. Conclusions. With a compressive load, the use of long screws allows to reduce the level of stress in the bone elements of the models, the use of crosslinks provides greater rigidity to the posterior support of the transpedicular structure, which leads to an increase in stress on the fixing screws but allows to reduce the level of stress in the bone tissue. [ABSTRACT FROM AUTHOR]

Introduction: Several targets have been proposed to achieve satisfactory alignment and favorable outcomes in adult spinal deformity surgery. Stopping the upper instrumented vertebra (UIV) at the thoracolumbar junction levels, especially between T11 and L1, is considered a high-risk factor for the development of proximal junctional kyphosis (PJK). Nevertheless, it is unknown in which patients the results of surgery are satisfactory when L1 or L2 is set as UIV with lumbosacral fixation. This study aimed to identify the risk factors for PJK in patients with lumbosacral fixation with L1 or L2 as UIV. Methods: From January 2011 to December 2019, 21 consecutive patients who underwent lumbopelvic fixation for adult spinal deformity were included. The patients were divided into two groups: the PJK group (n=7) and the nonPJK group (n=14). Patients who experienced PJK within half a year of surgery were included in the PJK group. Pelvic incidence (PI), lumbar lordosis (LL), pelvic tilt (PT), thoracic kyphosis (TK), thoracic compensation (TK compensation), sagittal vertical axis (SVA), T10-L2 angle, and T1 pelvic angle (TPA) were measured before and after surgery. Results: No difference was found between the two groups in terms of age and sex at the time of surgery. The indices that were significantly different between the two groups were preoperative PT, PI minus LL, TK, TPA, TK compensation, and postoperative T10-L2 angle. No significant differences were found in postoperative LL, PI minus LL, PT, TK, TPA, or SVA. Conclusions: Preoperative X-ray indices, including preoperative TPA, TK compensation, TK, PT, and PI-LL, determined the risk of PJK in fusions from the sacrum to L1 or L2. Appropriate patient selection is crucial for the success of this surgery.

Objectives: The extension of diffuse idiopathic skeletal hyperostosis (DISH) from the low thoracic spine to the lumbar spine result in adjustment of spinal sagittal alignment in surgical patients. The aim of this study was to investigate changes in sagittal alignment and back pain in the thoracolumbar spine in nonsurgical DISH and control participants selected from a radiological database. Methods: Participants in the DISH and the control group were selected by searching for "DISH or degenerative changes in the thoracic spine" in the radiology database of Taizhou Hospital between 2018 and 2021 using Resnick and Niwayama's criteria. The subjects with spinal tumors, previous spinal surgery, vertebral fractures, inflammatory diseases, poor-quality radiographs, or loss of follow-up were excluded. Demographic and clinical characteristics were recorded retrospectively via the hospital information system and telephone follow-up. Segmental disc angles (SDAs), lumbar lordosis (LL), and bridge scores were analyzed using images of three-dimensional CT. Results: The final participants consisted of 51 individuals with DISH (DISH group) and 102 individuals without DISH (control group). Depending on the presence of thoracolumbar pain, the DISH group was divided into the DISH group with thoracolumbar pain (DISH+Pain) and the DISH group without thoracolumbar pain (DISH-Pain). The LL and SDAs of T11-T12 and T12-L1 were significantly greater in the DISH group than in the control group. In addition, the SDA of L1-L2 was significantly smaller in the DISH+Pain group than in the DISH-Pain group, whereas there was no significant difference in lumbar lordosis between the DISH+Pain group and the DISH-Pain group. The bridge scores in DISH+Pain group was larger in T10-T11 (p = 0.01) and L1-L2 (p < 0.01) spine segments than those in DISH-Pain group. Conclusion: The extension of DISH from thoracic to lumbar spine may increase lumbar lordosis and SDAs in the thoracolumbar spine. The DISH patients with more bony bridging and small L1-L2 SDA may be more likely have thoracolumbar pain. Adjustment of sagittal alignment of the spine in the development of DISH may be of clinical importance. [ABSTRACT FROM AUTHOR]

Introduction: Lateral corpectomy has been considered a minimally invasive surgery, allowing a “transdiaphragmatic approach” at the thoracolumbar junction. This approach allows for a small diaphragmatic incision directly in the retroperitoneal space and the affected vertebra. However, its effectiveness in comparison to a conventional approach remains unclear. Thus, in this present study, we compared the surgical outcomes between conventional diaphragmatic detachment and the transdiaphragmatic approach in patients with vertebral fracture at the thoracolumbar junction. Methods: In total, 31 patients with a vertebral fracture at the thoracolumbar junction (T12-L2) were included in this study: 17 underwent a conventional approach, whereas 14 underwent a transdiaphragmatic approach, with a minimum 2-year follow-up. The effectiveness of surgery was evaluated in each category of the Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ). Results: Operative time and estimated blood loss were determined to be significantly shorter in the transdiaphragmatic than in the conventional approach. Perioperative complications were observed in the conventional approach (one atelectasis and one pleural effusion), while no complication was noted in the transdiaphragmatic approach. There were no significant differences in postoperative quality of life as assessed by JOABPEQ in terms of pain-related disorders, lumbar spine dysfunction, gait disturbance, social life dysfunction, or psychological disorders between the conventional and transdiaphragmatic approaches. Conclusions: A “transdiaphragmatic approach” using lateral access surgery has been found to be associated with a shorter operative time and less blood loss with fewer complications than the conventional approach. Given that equivalent clinical outcomes were achieved in both conventional and transdiaphragmatic approaches, this “transdiaphragmatic approach” could be useful because of its minimal invasiveness.

Background: Fixed severe hyperkyphotic deformities spread over more than five vertebral levels represent a therapeutic challenge, especially when the deformity apex is located at the thoraco-lumbar junction, thus requiring a huge amount of correction. The aim of this article is to describe an innovative all-posterior corrective technique based on multilevel non-contiguous thoracic pedicle subtraction ostoeotomy (PSO).Materials and Methods: A retrospective review of three patients with fixed severe thoracic hyperkyphosis (a deformity angle of over 70°) with a thoraco-lumbar apex (between T11 and L1) treated by simultaneous two-level thoracic PSO and thoraco-lumbar posterior fusion was performed. Radiographic and clinical records were evaluated pre-operatively, post-operatively and at last follow-up (after a minimum of 2 years). Each variable was presented as mean ± SD (standard deviation). Statistical analyses were performed using paired t-tests (P value < 0.05 was considered significant).Results: The mean local deformity angle decreased by 75% (from 81.3° ± 2.1° to 20.7° ± 1.4°, p < 0.001), the post-operative thoracic kyphosis decreased by 46% (from 61.4° ± 2.4° to 33.2° ± 0.9°, p < 0.001) and the sagittal vertical axis decreased by 73% (from 14.7 cm ± 0.8 cm to 3.9 cm ± 0.3 cm, p < 0.001). No differences were observed in the radiological results between post-operative values and those at the final follow-up. The average Oswestry Disability Index (ODI) score reduced from 65.7 ± 1.8 pre-operatively to 17.3 ± 1.7 at last follow-up (p < 0.001). No neurological, mechanical nor infective complication occurred.Conclusions: The presented technique, although technically demanding, proved to be a safe and effective alternative for the management of fixed severe thoraco-lumbar junction hyperkyphotic deformities.Level Of Evidence: IV TRIAL REGISTRATION Retrospectively registered. [ABSTRACT FROM AUTHOR]

The thoracolumbar junction is an area of the thoracic and lumbar spine, which accounts for more than 50 % of fractures. Despite the high frequency of damage to this area, unambiguous unified treatment of patients has not been developed. One of the most critical factors that determine both the overall strategy of care and surgical management (if necessary) is the pathomorphological characteristic of osteoligamentous injuries. The main tool for standardization and unification of tactical approaches is the classification of injuries. Since the thoracolumbar junction anatomically belongs to the thoracic and lumbar spine, lesions of this area are characterized according to the thoracolumbar injury classifications. However, a number of biomechanical features of the thoracolumbar junction determine tactics different from those for identical types of traumatic changes in other parts of the spine. This series of publications examines the current and most commonly used classifications in order to determine the algorithm with the help of which, based on the proposed classification categories, it would be possible to choose the optimal treatment of victims. The classification was considered that has been proposed in 1994 by F. Magerl et al. and was the standard in the ranking of traumatic injuries of the thoracic and lumbar spine for a long period of time. The classification is based on the principle of two supporting columns of the spine. When developing it, the authors used the clinical material of 1,445 patients. The classification is based on three main types of damage — compression, distraction and rotation. Each type is divided into groups and subgroups. Detailing is provided for a number of subgroups. In addition to a detailed review of the classification, the main parameters that contribute to or prevent the use of the analyzed ranking system in clinical practice are considered. Much attention is paid to the problem of reproducibility of results, as well as the impact of additional factors on the reliability of determining the nature of the damage. The classification provides a comprehensive description of all possible post-traumatic pathomorphological changes and has a proven biomechanical basis. Such details can be an important tool in determining the treatment of the lumbosacral junction lesion, as high requirements for rigidity of fixation are due to the significant load on this area and the features of biomechanics, which requires further study, since the analysis of the literature did not reveal a clear scheme for the therapy of these injuries. [ABSTRACT FROM AUTHOR]

The anatomical features of the thoracolumbar junction determine the significant predisposition of this area to traumatic injuries. The treatment tactics thoracolumbar junction lesion is quite controversial. A large number of methods have been proposed to demonstrate their effectiveness in various types of damage. However, a single concept that defines a specific method of treatment for a certain set of pathomorphological changes has not yet been formed. The trend of the last ten years is the development and active introduction into clinical practice of tactically oriented clinical classifications of traumatic injuries of sertain part of the spine. These classifications consider a number of heterogeneous factors and providе а clinician with a more or less clear scheme of therapeutic measures. As to the thoracolumbar junction, such a classification is AOSpine Thoracolumbar Spine Injury Classification System. The scheme was developed in order to characterize injuries of the entire thoracic and lumbar spine, while the features of the thoracolumbar junction, as in the previously proposed classifications, are practically not taken into account. The classification is based on the assessment of 3 basic criteria: the morphological characteristics of the fracture, the neurological status of the patient, and clarifying clinical modifiers. The hierarchy of the distribution of types of traumatic injuries corresponds to an increase in the severity degree. There are 3 main types: compression injuries; failure of the posterior or anterior ligamentous complex; damage accompanied by displacement in any plane. When developed the prurpose was the creation of a fairly simple, universal and well-reproducible classification in order to reflect global surgical preferences and determine the most rational approach to treatment. This review provides a detailed description of all damage options. It has been established that despite the high reproducibility of the results, the classification actually remains a descriptive tool, without assuming the definition of any tactics for each specific classified case. The thoracolumbar spine injury severity scale, which is based on the AO classification, is considered as a tool for quantitative assessment of the severity of injury. The scale, based on the sum of points characterizing a certain damage, allows you to make a choice in favor of either surgical or conservative treatment. The scheme proposed by the Spine Section of the German Society for Orthopaedics and Trauma is considered as the most detailed algorithm for the treatment of injuries to the thoracolumbar spine. The algorithm is based on the AOSpine Thoracolumbar Spine Injury Classification System, but uses a number of additional morphological modifiers, which made it possible to more adequately determine the most rational treatment method for a particular type of injury. [ABSTRACT FROM AUTHOR]

Background Short-segment transpedicular screw fixation (SSTSF) is the preferred treatment option for thoracolumbar burst fractures. Adding screws in the fractured body may be helpful in achieving and maintaining fracture reduction. However, the operative approach is disputed. Objective To compare clinical outcomes of transpedicular fixation with and without screws in the fractured vertebral body after isolated uncomplicated fractures at the thoracolumbar junction. Material and methods A retrospective cohort study enrolled 62 patients with Th11–L2 thoracolumbar burst fractures (AOSpine A3, A4) who underwent SSTSF with (n = 32) and without (n = 30) pedicle screws at the fracture level. Demographic data of the patients, operating time and blood loss were registered. Clinical evaluation using Visual analogue scale (VAS ) for pain, Oswestry Disability Index (ODI) to quantify disability and imaging parameters of segmental kyphosis, loss of correction, anterior vertebral body height (AVBH) at the fracture level, spinal canal stenosis (SCS) were measured preoperatively, at one week, 1 month, 6 and 12 months postoperatively. Results The patients of the two groups showed no statistically significant differences in the demographic data, VAS and ODI scores, measurements of kyphotic angle, AVBH, SCS preoperatively (p > 0.05). Screws at the fracture level did not affect the operating time and intraoperative blood loss relative to conventional no-screw group. Benefits with fracture screws were evident at 7 days (p < 0.01) measuring SCS, at 6 months (p < 0.01) and 12 (p < 0.01) months measuring kyphotic angle. There was better kyphosis correction (p < 0.01) and AVBH (p = 0.034) seen at 12 months after surgery. Conclusion Reinforcement of a broken vertebra with fracture-level screws has been shown to provide better stability of clinical and radiographic results as compared to those with conventional SSTSF.

Introduction: the segmented structure of the spinal column serves as an effective mechanism to transmit axial loading while simultaneously allowing stipulated movements in all six degrees of freedom at the spinal joints. The pattern of anteroposterior intra-vertebral loading dynamically shifts at the thoracolumbar (TL) and lumbosacral (LS) junctions where the line of gravity changes its position in the sagittal plane with respect to the spinal curvatures. Recent publications documenting morphological and clinical presentations of thoracolumbar transitional vertebrae (TLTV) and lumbosacral transitional vertebrae (LSTV) anomalies in the spine literature has prompted this perspective article as an attempt to collate probable biomechanical and etiological links between these two transitional anomalies. A summary of these propositions, as documented by clinical studies and hypothetical modelling, has been presented and discussed. [ABSTRACT FROM AUTHOR]

Background: The thoracolumbar junction (TLJ) represents a transition zone of the spine that leads to a high incidence of fractures. The treatment of burst fractures remains controversial regarding the ideal management. This study assessed the postoperative radiological outcome of TLJ fixation in patients with TLJ injuries who underwent surgery. Methods: All traumatic patients with TLJ injuries who were referred to the Khatam hospital of Zahedan between 2015 and 2020, with their thoracolumbar injury classification and severity score (TLICS) of four or more and who underwent surgery, were included in this study. The patients who entered the study were called for a follow-up examination. The degree of kyphosis, proximal junctional kyphosis, and fusion were assessed in these patients. Results: Among 273 patients, the average age was 43.5 ± 12.3 (21-73) years. One hundred and ninety-eight patients (72.5%) had no neurological symptoms at admission. Based on the above criteria, the kyphosis angle of these patients was calculated before surgery, which in 46 patients (16.8%), the kyphosis angle was more than 25°. Preoperation kyphosis was significantly associated with follow-up kyphosis (P < 0.001). Evidence of no fusion was also observed in 22 patients (8.1%). According to the Chi-square test, no association was observed between preoperative kyphosis and postoperative complications, including PJK and fusion (P > 0.05). Conclusion: According to our study, the posterior spinal fixation procedure is a low-complication method with an acceptable radiological outcome. Although kyphosis before surgery is a factor in developing long-term kyphosis, it is not associated with nonfusion and PJK. [ABSTRACT FROM AUTHOR]

Objective Thoracolumbar disc herniation is an uncommon disabling spine condition. Methods There is relatively large dura expansion to lateral recess in the thoracolumbar junction leading to potential hazard in docking and execution of endoscopic transforaminal discectomy. Mobile outside in technique had been executed successfully in lumbar disc herniation, we modified the technique to allow safe docking and execution of discectomy in thoracolumbar junction. Herein, we report a case of thoracic twelve lumbar one disc paracentral disc herniation treated with floating transforaminal endoscopic discectomy under local anesthesia. Results A 46-year-old man with a 3-months of severe back and radicular pain on the right groin. A diagnosis of right T12/L1 paracentral disc herniation was made, based on clinical and radiological investigations. He underwent percutaneous transforaminal endoscopic thoracolumbar discectomy with floating technique. Over a follow-up of 6 months, a favorable outcome was noted. Conclusion Floating technique of transforaminal endoscopic thoracolumbar junction discectomy is a safe and an effective surgical approach for the treatment of thoracolumbar disc herniation. In patients with thoracolumbar disc herniation, careful patient selection and evaluation neural elements anatomy in relation to bony anatomy is important in preparation for endoscopic decompression.

Postoperative pain management following spine surgery remains a significant challenge, often requiring multimodal approaches to achieve adequate analgesia while minimizing side effects. The thoracolumbar interfascial plane (TLIP) block has emerged as a novel regional anesthesia technique for addressing this issue. By targeting the interfascial plane between the erector spinae and quadratus lumborum muscles at the thoracolumbar junction, the TLIP block aims to provide targeted analgesia to the surgical site while reducing systemic opioid requirements. This review explores the anatomy, technique, mechanism of action, and clinical evidence supporting the TLIP block for post-spine surgery pain management. Additionally, it compares the TLIP block with traditional pain management approaches and discusses its implications for clinical practice and future research. Overall, the TLIP block shows promise as an effective and potentially safer alternative for post-spine surgery pain management, potentially improving patient outcomes and enhancing recovery. Further research is warranted to optimize its utilization and comprehensively evaluate its long-term effects., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Gajapure et al.)

The thoracolumbar junction (TLJ) is the most common site of traumatic spinal injury. Its management is a highly controversial area. There are no specific guidelines for management of these injuries. The primary goal of treatment of TLJ fractures involves protecting the spinal cord from further neural damage, obtaining the stability by reconstructing anatomical alignment of spinal column, and returning patients to workplace through early mobilization and rehabilitation. There is a great variation in evaluation of stability of these fractures, which is one of the crucial factors in deciding the treatment. Controversy also exists regarding conservative versus operative treatment, timing of intervention, anterior versus posterior approach, short versus long segment fixation, and bracing versus no bracing. This article had reviewed the conflicting results and recommendations for management of TLJ fractures of previously published reports in PubMed, PubMed Central, and Medline databases. We analyzed these related articles which addresses issues regarding evaluation of stability, indications for operative and conservative treatment, timing of surgery, surgical approach, and fusion length. [ABSTRACT FROM AUTHOR]

Abstract Background A multicentre retrospective study was conducted to evaluate the safety and efficacy of single-stage posterior debridement, decompression and transpedicular screw fixation for the treatment of thoracolumbar junction (T12-L1) tuberculosis in patients with associated neurological deficit. Methods Thoracolumbar junction (T12-L1) tuberculosis patients (n = 69) with neurological deficit who underwent single-stage posterior debridement, decompression and transpedicular screw fixation from January 2005 to January 2015 were included in the study. Antituberculosis therapy was performed both before and after surgery. The surgery duration and patient blood loss were evaluated, in addition to the change in pain visual analogue score (pVAS), kyphotic angle, Oswestry disability index (ODI) score and American Spinal Injury Association (ASIA) grade assessed preoperatively, immediate postoperatively and at the final follow-up visit. Results The average blood loss was 354 ± 291 mL. The average kyphosis angle was corrected from 21 ± 9° preoperatively to 9 ± 4° postoperatively, with a mean decrease in pVAS and ODI scores of 3.4 and 16, respectively. The postoperative ASIA grading was grade A for five patients, grade C for 15 and grade D for 49 patients, which had improved to grade C for four patients, grade D for three patients and grade E for 62 patients at the final follow-up. The neurological deficit did not worsen in any of the patients. Conclusions Single-stage posterior debridement, decompression and transpedicular screw fixation is an effective treatment method in thoracolumbar junction (T12-L1) tuberculosis patients with neurological deficit, with good neurological recovery and no progression of kyphosis.

Background: Thoracolumbar vertebral fractures are common in high-energy trauma and often are associated to other concomitant injuries. Currently, brace and Closed Reduction and Casting (CRC) are the two conservative treatments proposed by literature. Despite CRC was widely used in the past, today brace is preferred. The aim of our study is to evaluate clinical and radiographic outcomes of thoracolumbar type A fractures, not associated with other injuries, treated with CRC. Materials and Methods: We retrospectively evaluated all patients treated from 2008 to 2015, with a mean age of 26.69 years (range 15–45). All patients were affected by AO type A fracture: 26 type A1, 17 type A2, and 21 type A3. All patients were evaluated by X-ray, computed tomography, and magnetic resonance imaging. Radiological evaluations included vertebral kyphosis (VK), segmental kyphosis (SK), regional kyphosis (RK) angle, and vertebral ratio (VR) measures. Patients were clinically assessed through visual analog scale, Oswestry Disability Index, Roland–Morris Disability Questionnaire, and Short Form 36 Health Survey. Results: Seventy-four patients (41 males and 33 females) were included in the study. At follow-up (mean 28.48 months ± 5.16), we found significant improvements in VK (P = 0.000013), SK (P = 0.000455), and RK (P = 0.000016). No significant differences were observed in VR (P = 0.26). Good clinical results were reported in patients in all scores and 90.7% of patients returned to work. Conclusions: Closed reduction and casting is still a reliable treatment option in selected thoracolumbar fractures without spinal cord involvement. A correct fracture evaluation, patient compliance, and motivation are essentials. Level of evidence: IV.

Objective. To analyze the 50 most cited articles related to the diagnosis, classification and surgical treatment of injuries of the thoraco- lumbar junction, which influenced the study of this problem. Material and Methods. The Web of Science database was searched for keywords to detect articles related to thoracolumbar junction sur- gery. Articles were selected taking into account the title, abstract and the used methods, and then evaluated by the total number of cita- tions to identify the fifty most cited. Characteristics of publications were analyzed. Results. The United States of America, Thomas Jefferson University and A.R. Vaccaro were the most productive country, institution and author, respectively, dealing with the subject. The 2000s was the most active decade in terms of the number of publications. The great- est attention of scientists dealing with the problems of thoracolumbar injury was attracted by the article by McLain et al. analyzing the causes of the failures of short-segment transpedicular systems in the early postoperative period. The article by Laursen et al. presenting the results of using recombinant bone morphogenetic protein-7 in combination with metal fixation is at the top of the list in terms of aver- age citation index. Most articles are well-designed randomized studies with the evidence level II. Conclusion. Citation analysis allowed to identify the most relevant articles, the authors of which have made a significant contribution to the problem of surgery of the thoracolumbar junction. Study of the information field through the prism of the most cited articles allows seeing the mainstream and future development of diagnostics, classification and treatment of the injuries of this localization.

To determine various morphometric parameters like transverse and sagittal pedicle width; interpedicular distance; antero-posterior and transverse canal diameter and canal surface area at thoracolumbar junction (T11, T12, L1, L2) in central Indian population and compare results with similar studies available in literature. A prospective, computerized tomography scan based morphometric analysis of thoracolumbar junction was conducted at medical college and tertiary care centre in central India. All asymptomatic cases more than 18 years age with normal lateral radiograph and CT scan of thoracolumbar junction and free from any spinal pathology or trauma were included in the study. Parameters measured were transverse and sagittal pedicle width; interpedicular distance; antero-posterior and transverse canal diameter and canal surface area at thoracolumbar junction (T11, T12, L1, L2). Mean transverse pedicle width was maximum at T11 and minimum at L1 in both males and females, whereas sagittal width was maximum at T11 and minimum at L2 in both the groups. Interpedicular distance was largest at L1 in both the groups. All the measurements were significantly different (P < 0.05) in males and females. Mean antero-posterior and transverse diameter was maximum at T12 and L2 respectively in both male and female study population. Canal surface area was maximum at L1 among males (230.10 mm2) as well as females (209.02 mm2). There is significant variation in morphometric parameters of thoracolumbar junction in different races and population. Thorough knowledge of morphometry of a particular population is essential for dealing with pathology or trauma of thoracolumbar junction. [ABSTRACT FROM AUTHOR]

Objectives: Studies have demonstrated that there is an increased thoracolumbar junction sagittal Cobb angle (TLJS) in thoracolumbar/lumbar adolescent idiopathic scoliosis (AIS) patients. The objectives were to ascertain the correlations between the spinopelvic alignments and TLJS and to explore potential predictive factors for hyperkyphotic TLJS in the sagittal plane in thoracolumbar/lumbar AIS.Methods: A total of 114 AIS patients with thoracolumbar/lumbar curve were included. Cobb angle, apical vertebrae rotation (AVR), thoracic kyphosis (TK), TLJS, lumbar lordosis (LL), pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), T1-spinopelvic inclination (T1-SPI), and T9-spinopelvic inclination (T9-SPI) were measured. After patients were organized into two subgroups based on TLJS, all parameters were compared between the two groups. Correlation analysis and multiple linear regression analysis were performed between the radiologic measurements and TLJS in all patients.Results: There was a significant difference between the non-kyphotic group and kyphotic group in mean Nash-Moe grade, TK, T9-SPI, PI, and SS. Correlation analysis showed that LL, PI, and SS were inversely associated with TLJS. TK, T9-SPI, and Nash-Moe grade were positively related to TLJS. The multiple linear regression analysis showed that TLJS could be predicted by the equation TLJS = −2.322 + 5.585 × Nash-Moe grade + 0.687 × T9-SPI – 0.208 × PI, with an adjusted R2 of 0.410.Conclusion: TLJS was positively correlated with greater AVR in the coronal plane, greater T9-SPI in the sagittal plane and inversely associated with PI among patients with thoracolumbar/lumbar scoliosis. Spine surgeons should pay more attention to the degree of AVR, T9-SPI, and PI when dealing with thoracolumbar/lumbar scoliosis with thoracolumbar junction kyphosis.

Introduction Treatment of osteoporotic vertebral fractures (OVFs) is a factor that affects the quality of life and should be considered during management. In patients with a single OVF and neurologic deficit, surgical procedures aiming at neural decompression with instrumented fusion should be considered in elderly individuals. Posterolateral instrumented fusion (PLF) constitutes a largely performed fusion surgery for patients featuring indications for fusion surgery. The aim of this study was to determine the safety, effectiveness, and impact on health-related quality of life (HRQoL) of PLF surgery in elderly patients diagnosed with a single OVF. Methods This study was conducted at Interbalkan European Medical Center, Thessaloniki, Greece. Eighty (80) consecutive individuals with OVFs were subjected to PLF and recruited in this prospectively designed non-randomized study. Clinical evaluation was performed preoperatively and postoperatively at particular chronic intervals at one, three, six, and 12 months and two years. The assessment was conducted via the standardized Visual Analogue Scale (VAS) and Short-Form 36 (SF-36) Medical Health Survey Questionnaire for pain and HRQoL, respectively. Results No major perioperative complications were observed. All parameters of SF-36 presented significant improvement over the entire follow-up period with VAS scores reaching a plateau at six months. Depicted improvement of these parameters proves the beneficial role of PLF in elderly patients who suffered from a single OVF with or without referable neurological deficit. Conclusion OVFs have a significant impact on the quality of life of elderly patients, and surgical treatment with PLF with or without decompression can lead to functional recovery, pain relief, and HRQoL amelioration. Our results demonstrated that the outcomes of PLF in the surgical treatment of these patients are remarkably favorable, demonstrating the safety and efficacy of the technique., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Kapetanakis et al.)

Degenerative thoracic stenosis has been shown to most frequently involve the lower thoracic segments (T9-T12) where there is greater mobility and vulnerability due to flexion, extension and rotation of the spine. The thoracolumbar junction is considered anatomically to be T12-L1; the anatomical transition between the relatively immobile thoracic spine and relatively mobile lumbar spine. From anecdotal experience at our institution, we hypothesise that the true thoracolumbar junction is higher, at T10-11; the point of transition from floating to false ribs resulting in increased mobility at T10-11. A retrospective review was performed of MRI lumbar and whole spine performed on patients aged 10–40 years in our institution over a 5-year period. Patients with previous surgery, chronic spinal disorders and congenital abnormalities were excluded from the study. Intervertebral discs from T8-9 to L1-2 were assessed for evidence of degeneration using the Pfirrmann grading system. Data obtained from a study using computer-based models to assess mean resultant loads in flexion, sitting and standing from T8-9 to L1-2 on patients aged 18–35 years was also analysed. The mean load gradients between two consecutive discs from T8 to L2 were analysed. Statistical analysis was performed with SPSS (p < 0.05 was considered statistically significant). Three-hundred and twenty-two MRI studies were reviewed. Mean Pfirrmann grade was highest at T8-9 and T9-10 (1.35 ± 0.99 and 1.32 ± 0.93 respectively).Pfirrmann grade differed significantly at each level (χ2 = 45.137 p = 0.001). Difference in mean load gradient from T9 to T11 was significantly higher than mean load gradient across T11 to L1 in both sitting and standing (0.095 ± 0.062 vs 0.050 ± 0.044 kN; p = 0.007, and 0.101 ± 0.061 kN vs 0.040 ± 0.054 kN; p = 0.007). The changes in segmental loads and more severe disc degeneration at T9-11 compared to T11-L1 support our hypothesis that the true thoracolumbar transition is higher than expected, at T10-11; where the rib cage transitions from floating to false ribs. [ABSTRACT FROM AUTHOR]

Study Design: Retrospective study.Objective: The aim of this study was to investigate the risk factors for proximal junctional failure (PJF) following long instrumented fusion stopping at thoracolumbar junction (TLJ) in adult spinal deformity (ASD) and to determine which cases are suitable for TLJ stop without increasing the risk for PJF.Summary Of Background Data: PJF following long fusion for ASD is a well-recognized complication that negatively affects clinical outcomes. Generally, the uppermost instrumented vertebra (UIV) at the TLJ is associated with the risk of PJF. Little is known about the risk factors for PJF in case with the UIV at TLJ.Methods: Radiographic and clinical data of 63 consecutive patients who underwent instrumented fusion from sacrum to TLJ (T11, T12, and L1) for the treatment of ASD with a minimum 2-year follow-up were analyzed to identify the risk factors for PJF, which was defined as proximal junctional angle (PJA) ≥20°, fracture at UIV or UIV+1, failure of UIV fixation, myelopathy, or 'need for proximal extension of fusion.Results: During the average follow-up duration of 51.7 months, PJF developed in 23 patients (36.5%) at a mean of 9.3 months after surgery. Multivariate analysis revealed that age >70 years (odds ratio [OR]: 1.119), osteoporosis (OR: 4.459), and preoperative kyphotic PJA (OR: 1.138) were significant risk factors for the development of PJF. No PJF occurred in 14 patients lacking any risk factors. The last follow-up clinical results were significantly inferior in the PJF group than in the non-PJF group in terms of Oswestry Disability Index and Scoliosis Research Society-22 score.Conclusion: Age >70 years, osteoporosis, and PJA greater 0° were identified as significant risk factors for PJF. Therefore, the TLJ level can be considered as UIV selectively for patients younger than 70 years without osteoporosis and with lordotic preoperative PJA.Level Of Evidence: 3. [ABSTRACT FROM AUTHOR]

Purpose: Tethered cord syndrome (TCS) usually presents with low-lying conus medullaris and thickened filum terminale. Spinal cord anomalies usually accompany congenital malformations and variations of the vertebral column. Transitional vertebrae (TV) are common variant, especially in the lumbosacral region. Accurate definition of the spine level is essential for proper radiological diagnosis and treatment. In this study, congenital spinal cord and vertebral anomalies and the relation with TV groups and types were evaluated in TCS patients. Methods: The study was performed in 97 patients. Radiological imaging findings [computed tomography (CT), magnetic resonance imaging (MRI), and radiography] and medical records were evaluated. Spine bony malformation, spinal cord malformation, and spinal level of malformation were compared with TV and non-TV groups in TCS patients. In addition, TV groups and types were compared with each other for these anomalies. Results: There was no statistically significant difference between TV and non-TV group in terms of the presence of vertebral bone and spinal cord anomalies. There were some significant differences in some of the spine bone and spinal cord anomalies among the groups and types of TV. Conclusion: Sixty-two point nine percent TCS patients had TV. Although these findings indicate that TV is common in patients with TCS, no significant difference is observed in most of the studied anomalies. However, there were some differences among the TV groups and TV types in relation to congenital malformations. It can be concluded that TV anomaly could be a distinct malformation apart from all the other anomalies that were studied. Transitional vertebrae may cause pain due to biomechanical changes in addition to progressive neurological symptoms which are usually seen with TCS. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study is to determine the demographic and clinical characteristics of patients who underwent kyphoplasty due to osteoporotic fractures. Materials and Methods: This retrospective study included 55 patients who underwent kyphoplasty due to osteoporotic fracture between the years 2011 and 2014. The patients divided into two groups according to their ages (under/over 65 years), and divided into three groups according to fracture regions (T10 and above; between T11-L1; L2 and under). Thus the age and gender distributions of the patients were made. Resting pain scores of all patients were determined by using visual analog scale (VAS) and daily life activities by Oswetry Disability Index (ODI) before and in the first month of treatment. Results: Seventeen of the all patients were male (30.9%) and 38 were female (69.1%), with a mean age of 69.9±8.7 years (between 50-88 ages). 90% of the patients older than 65 years had fracture in T11 and below. In 45.5% of all patients, the fracture was in the T11-L1 (thoracolomber junction) region. Resting VAS and ODI scores significantly improved from 8.7±1.5 to 2.1±1.2 and 44.7±7.2 to 15.4±3.5 respectively in the first month after kyphoplasty (p

Aims: A retrospective analysis of patients with thoracolumbar junction fractures who underwent video-assisted thoracoscopic surgery via a minimally invasive approach (minithoracotomy) for reconstruction of the anterior spinal column. Methods: Between 2002 and 2014, a total of 176 patients were treated by this technique. The patients received either posterior stabilization and, at the second stage, the minimally invasive technique via an anterior approach, or the minimally invasive anterior procedure alone. Results: In the anterior procedure, the average operative time was 90 min. (50 to 130 min). Bony fusion without complications was achieved in all patients within a year of surgery. The loss of correction after the anterior procedure with an allograft or titanium cage was up to 2 degrees at two years follow-up. Conclusion: The minimally invasive approach (minithoracotomy up to 6-7 cm) combined with thoracoscopy is an alternative to an exclusively endoscopic technique enabling us to provide safe surgical treatment of the anterior spinal column.