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516 results on '"tRNA Methyltransferases genetics"'

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2. TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice.

3. Conserved 5-methyluridine tRNA modification modulates ribosome translocation.

4. How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA.

5. Modifications in the T arm of tRNA globally determine tRNA maturation, function, and cellular fitness.

6. Fluoropyrimidines trigger decay of hypomodified tRNA in yeast.

7. Structural basis for human mitochondrial tRNA maturation.

8. Arabidopsis AN3 and OLIGOCELLULA genes link telomere maintenance mechanisms with cell division and expansion control.

9. Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease.

10. Chemical manipulation of m 1 A mediates its detection in human tRNA.

11. Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes.

13. Pathological mutations promote proteolysis of mitochondrial tRNA-specific 2-thiouridylase 1 (MTU1) via mitochondrial caseinolytic peptidase (CLPP).

14. The epigenetic downregulation of LncGHRLOS mediated by RNA m6A methylase ZCCHC4 promotes colorectal cancer tumorigenesis.

15. CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.

16. A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae .

17. Identification of hepatoblastoma susceptibility loci in the TRMT6 gene from a seven-center case-control study.

18. Function of m 5 C RNA methyltransferase NOP2 in high-grade serous ovarian cancer.

19. Diversity in Biological Function and Mechanism of the tRNA Methyltransferase Trm10.

20. TCF7L2 (rs7903146) But Not CDKAL1 (rs7754840) Gene Polymorphisms Increase the Risk of New-Onset Diabetes After Kidney Transplant.

21. Crosstalk between the tRNA methyltransferase Trm1 and RNA chaperone La influences eukaryotic tRNA maturation.

22. The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infection.

23. Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function.

24. Human TRMT1 catalyzes m 2 G or m 2 2 G formation on tRNAs in a substrate-dependent manner.

25. Biallelic variants in NSUN6 cause an autosomal recessive neurodevelopmental disorder.

26. N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing.

27. Genotypic and phenotypic spectrum of infantile liver failure due to pathogenic TRMU variants.

28. CDKAL1 Drives the Maintenance of Cancer Stem-Like Cells by Assembling the eIF4F Translation Initiation Complex.

29. FTO demethylates m6A modifications in CDKAL1 mRNA and promotes gastric cancer chemoresistance by altering mitochondrial dynamics.

30. Loss of tRNA methyltransferase 9 and DNA damage response genes in yeast confers sensitivity to aminoglycosides.

31. Differential expression of m 5 C RNA methyltransferase genes NSUN6 and NSUN7 in Alzheimer's disease and traumatic brain injury.

32. Association of the CDKAL1 gene polymorphism with gestational diabetes mellitus in Chinese women.

33. The triglyceride glucose index and CDKAL1 gene rs10946398 SNP are associated with NAFLD in Chinese adults.

34. Targeting TRMT5 suppresses hepatocellular carcinoma progression via inhibiting the HIF-1α pathways.

35. Association of CDKAL1 gene polymorphism (rs10946398) with gestational diabetes mellitus in Pakistani population.

36. Functional analysis of tRNA modification enzymes using mutational profiling.

37. Sex Differences in the Effects of CDKAL1 Variants on Glycemic Control in Diabetic Patients: Findings from the Korean Genome and Epidemiology Study.

38. Integrative analysis of m3C associated genes reveals METTL2A as a potential oncogene in breast Cancer.

39. A novel mutation in TRMT5 associated with idiopathic non-cirrhotic portal hypertension and hepatopulmonary syndrome: Case report of two siblings.

40. Perioperative Management of Liver Retransplant in an Adult With a History of TRMU Alteration.

41. Genetic correction of TRMU allele restored the mitochondrial dysfunction-induced deficiencies in iPSCs-derived hair cells of hearing-impaired patients.

42. A novel TRMT5 mutation causes a complex inherited neuropathy syndrome: The role of nerve pathology in defining a demyelinating neuropathy.

43. Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data.

44. Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine- N 2 -) Methyltransferase (Trm11-Trm112 Complex).

45. A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription.

46. The CDKAL1 rs7747752-Bile Acids Interaction Increased Risk of Gestational Diabetes Mellitus: A Nested Case-Control Study.

47. Novel heterozygous compound TRMT5 mutations associated with combined oxidative phosphorylation deficiency 26 in a Chinese family: a case report.

48. Association of CDKAL1 RS10946398 Gene Polymorphism with Susceptibility to Diabetes Mellitus Type 2: A Meta-Analysis.

49. METTLing in the right place: METTL8 is a mitochondrial tRNA-specific methyltransferase.

50. Evolutionary repair reveals an unexpected role of the tRNA modification m1G37 in aminoacylation.

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