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Your search keyword '"spinal cages"' showing total 3 results
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3 results on '"spinal cages"'

1. Plasma treatment on novel carbon fiber reinforced PEEK cages to enhance bioactivity

Author

Banghard Michael, Freudigmann Christian, Silmy Kamel, Stett Alfred, and Bucher Volker

Subjects
cell tests, cfr peek, osseointegration, plasma, pvd, spinal cages, surface roughness, Medicine
Abstract

Carbon fiber reinforced polyetheretherketone (CFR-PEEK) has similar mechanical properties to human bone and is considered as the best alternative material to substitute titanium for spine cage implants. To compensate its poor osteogenic properties and limited bioinertness, CFR-PEEK was coated with a thin film of titanium. In the study, we investigated the biological response in vitro of titanium coated CFR-PEEK with different vacuum plasma pretreatments. The so modified surface revealed first hints for a good cell response by excellent cell adhesion and morphology of human osteoblast – like cells MG 63 (ATXX:’CRL-1427). Thus, the findings show that surface roughness of CFR-PEEK material has a profound effect on the biological activity via vacuum plasma treatment.

Published
2016
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2. Optimization of titanium spinal cages to maximize synthetic graft content in composite implants

Author

Ghandour, Salim, Isaksson, Per, Persson, Cecilia, Ghandour, Salim, Isaksson, Per, and Persson, Cecilia

Abstract

Spinal fusion is the gold standard for treating patients with degenerative disc disease. Titanium alloys and PEEK are the two most common materials used to manufacture cages for spinal fusion, used to maintain disc height while the vertebrae fuse. Other materials, such as morselised bone, may be added to the cage to enhance the bioactivity. A monetite-based calcium phosphate has (as a composite implant in combination with titanium) shown potentially osteoinductive properties and may be a synthetic alternative to bone graft. Maximizing the ratio of calcium phosphate to titanium could be desirable to maximize bone ingrowth and fusion. Further, the calcium phosphate can be incorporated into the cage and stored ahead of surgery. The aim of this study was to topologically optimize cervical spine implants to incorporate a bioactive but mechanically weak material such as calcium phosphate.

Published
2022

3. Plasma treatment on novel carbon fiber reinforced PEEK cages to enhance bioactivity

Author

Alfred Stett, Kamel Silmy, Christian Freudigmann, Michael Banghard, and Volker Bucher

Subjects
0301 basic medicine, Materials science, cell tests, Biomedical Engineering, osseointegration, Plasma treatment, 02 engineering and technology, Plasma, 021001 nanoscience & nanotechnology, spinal cages, Osseointegration, pvd, 03 medical and health sciences, 030104 developmental biology, cfr peek, surface roughness, Peek, Surface roughness, Medicine, Composite material, 0210 nano-technology, plasma
Abstract

Carbon fiber reinforced polyetheretherketone (CFR-PEEK) has similar mechanical properties to human bone and is considered as the best alternative material to substitute titanium for spine cage implants. To compensate its poor osteogenic properties and limited bioinertness, CFR-PEEK was coated with a thin film of titanium. In the study, we investigated the biological response in vitro of titanium coated CFR-PEEK with different vacuum plasma pretreatments. The so modified surface revealed first hints for a good cell response by excellent cell adhesion and morphology of human osteoblast – like cells MG 63 (ATXX:’CRL-1427). Thus, the findings show that surface roughness of CFR-PEEK material has a profound effect on the biological activity via vacuum plasma treatment.

Published
2016
Full Text
View/download PDF

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