Search

Your search keyword '"sodium stiboglu-conate"' showing total 2 results
Start Over Descriptor "sodium stiboglu-conate"
2 results on '"sodium stiboglu-conate"'

1. Safety and Efficacy of Prosopis juliflora Leaf Extract as a Potential Treatment against Visceral Leishmaniasis in Balb/c Mice

Author

Muendo Charity Mutile, Mutiso Joshua Muli, and Gicheru Michael Muita

Subjects
prosopis juliflora, sodium stiboglu-conate, balb/c mice, leishmania donovani, Infectious and parasitic diseases, RC109-216
Abstract

Background: Visceral Leishmaniasis caused by Leishmania donovani is a major health problem in the tropics and sub-tropic regions where it is endemic. We aimed in testing the leishmanicidal activity and toxicity of Prosopis juliflora leaf extract in BALB/c mice and in vitro test systems respectively. Methods: In the year 2017 until 2019, BALB/c mice of mixed sexes aged between 6 and 8 weeks in groups of 8 were used. Group I treated with 100 mg/kg of P. juliflora extract, Group II -1 mg/kg of Sodium stibogluconate (SSG) and Group III treated with normal saline. All mice were anaesthized and sacrificed to obtain blood, spleen samples for antibody measurements, and determination of parasite loads. Results: There was significant inhibitory effect (P

Published
2021

2. Safety and Efficacy of Prosopis juliflora Leaf Extract as a Potential Treatment against Visceral Leishmaniasis in Balb/c Mice

Author

Mutiso Joshua Muli, Gicheru M. Muita, and Muendo Charity Mutile

Subjects
biology, Traditional medicine, Leishmania donovani, Infectious and parasitic diseases, RC109-216, biology.organism_classification, medicine.disease, prosopis juliflora, BALB/c, sodium stiboglu-conate, Infectious Diseases, Visceral leishmaniasis, Prosopis juliflora, leishmania donovani, medicine, Parasitology, balb/c mice
Abstract

Background: Visceral Leishmaniasis caused by Leishmania donovani is a major health problem in the tropics and sub-tropic regions where it is endemic. We aimed in testing the leishmanicidal activity and toxicity of Prosopis juliflora leaf extract in BALB/c mice and in vitro test systems respectively. Methods: In the year 2017 until 2019, BALB/c mice of mixed sexes aged between 6 and 8 weeks in groups of 8 were used. Group I treated with 100 mg/kg of P. juliflora extract, Group II -1 mg/kg of Sodium stibogluconate (SSG) and Group III treated with normal saline. All mice were anaesthized and sacrificed to obtain blood, spleen samples for antibody measurements, and determination of parasite loads. Results: There was significant inhibitory effect (P

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results