21 results on '"skin oiliness"'
Search Results
2. Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin
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Emil A. Tanghetti, Joshua A. Zeichner, Michael Gold, Neil Sadick, Fran E. Cook-Bolden, Leon H. Kircik, Linda Stein Gold, Jonathan Weiss, Stephen K. Tyring, James Q. Del Rosso, and Eric Guenin
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tazarotene ,retinoid ,acne ,skin oiliness ,Dermatology ,RL1-803 - Abstract
Background Excessive sebum production is a factor in acne development. Tazarotene 0.045% lotion has demonstrated reductions in acne lesions and acne-induced sequelae. Objective Evaluate efficacy, changes in skin oiliness, and safety with tazarotene 0.045% lotion in participants with moderate-to-severe acne and oily skin. Methods In two phase 3, double-blind, 12-week studies (NCT03168321; NCT03168334), participants aged ≥ 9 years with moderate-to-severe acne were randomized 1:1 to once-daily tazarotene 0.045% lotion or vehicle lotion (N = 1614). This pooled, post hoc analysis included only participants self-categorized with oily skin at baseline on the Acne-Specific Quality of Life questionnaire item 19 (scores: 0 [extremely oily] to 6 [not at all oily]). Inflammatory/noninflammatory lesion counts, treatment success, skin oiliness, treatment-emergent adverse events (TEAEs), and cutaneous safety/tolerability were evaluated. Results In all participants with oily skin (n = 793), tazarotene provided greater reductions in inflammatory/noninflammatory lesions (p
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- 2023
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3. Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin.
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Tanghetti, Emil A., Zeichner, Joshua A., Gold, Michael, Sadick, Neil, Cook-Bolden, Fran E., Kircik, Leon H., Stein Gold, Linda, Weiss, Jonathan, Tyring, Stephen K., Del Rosso, James Q., and Guenin, Eric
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OINTMENTS ,ACNE ,FACTORS of production ,QUALITY of life ,SEBUM - Abstract
Excessive sebum production is a factor in acne development. Tazarotene 0.045% lotion has demonstrated reductions in acne lesions and acne-induced sequelae. Evaluate efficacy, changes in skin oiliness, and safety with tazarotene 0.045% lotion in participants with moderate-to-severe acne and oily skin. In two phase 3, double-blind, 12-week studies (NCT03168321; NCT03168334), participants aged ≥ 9 years with moderate-to-severe acne were randomized 1:1 to once-daily tazarotene 0.045% lotion or vehicle lotion (N = 1614). This pooled, post hoc analysis included only participants self-categorized with oily skin at baseline on the Acne-Specific Quality of Life questionnaire item 19 (scores: 0 [extremely oily] to 6 [not at all oily]). Inflammatory/noninflammatory lesion counts, treatment success, skin oiliness, treatment-emergent adverse events (TEAEs), and cutaneous safety/tolerability were evaluated. In all participants with oily skin (n = 793), tazarotene provided greater reductions in inflammatory/noninflammatory lesions (p < 0.001, both) and greater treatment success rates versus vehicle (p < 0.01) at week 12. Over two-thirds of polymeric lotion-treated participants had subjective skin oiliness reductions by week 12, with around a third reporting 'low/not' oily skin. Tazarotene TEAE rates were similar to the overall population. Once-daily treatment with tazarotene 0.045% polymeric emulsion lotion may help improve patient-perceived skin oiliness in those with moderate-to-severe acne. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Therapeutic non-contraceptive properties of the drug containing ethinylestradiol 0.03 mg and drospirenone 3 mg
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Natalia V Artymuk and Olga A Tachkova
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ethinylestradiol ,drospirenone ,acne ,hirsutism ,skin oiliness ,Gynecology and obstetrics ,RG1-991 - Abstract
Aim. To compare effects of the drug containing ethinylestradiol (EE) 0.03 mg and drospirenone (DRSP) 3 mg and the drug containing EE 0.02 mg and DRSP 3 mg on the skin and anthropometric parameters. Materials and methods. A prospective comparative randomized study included 40 women of reproductive age who didn’t have contraindications to use of combined oral contraceptive (COCs). The first group consisted of 20 women who were administrated EE 0.03 mg and DRSP 3 mg in the 21/7 regimen according to a prescribing information; the 2nd group included 20 patients who were administrated EE 0.02 mg and DRSP 3 mg in the 24/4 regimen according to a prescribing information. The study protocol included 8 visits: at the 0th visit, the inclusion and exclusion criteria were evaluated, at the 1st visit patient were randomized (envelope method) to receive one or another drug, at the 2nd - 7th visits (once a month) blood pressure was measured, anthropometric parameters were determined including body weight, height, waist, hips as well as body mass index, a degree of hirsutism (with Ferriman-Gallwey scale), skin and hair skin oiliness, acne (with a 10-point visual scale) were evaluated. Results. The use of EE 0.03 mg and DRSP 3 mg for 6 months did not significantly affect the body weight and body mass index, waist and hips. In the 6th month, the use of EE 0.03 mg and DRSP 3 mg lead to a statistically significant decrease in skin oiliness, severity of acne and hirsutism, which was comparable to a clinical effectiveness of EE 0.02 mg and DRSP 3 mg. Conclusions. EE 0.03 mg and DRSP 3 mg has a similar effect on skin oiliness, severity of acne and hirsutism with EE 0.02 mg and DRSP 3 mg, without significantly affecting the main anthropometric parameters. It is likely that the effect of DRSP-containing COCs on androgen levels and adipose tissue is due precisely to the effect of DRSP, and not to the dose of EE.
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- 2019
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5. Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post‐inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris.
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Campos, Valeria, Pitassi, Luiza, Kalil, Célia, Gonçalves Júnior, José Euzébio, Sant'Anna, Beatriz, and Correia, Priscila
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ACNE , *CITRIC acid , *SALICYLIC acid , *HYPERPIGMENTATION , *GLYCOLIC acid , *ADULTS , *DIAGNOSIS - Abstract
Background: Acne is a chronic disease that affects the pilosebaceous follicle and is characterized by the presence of non‐inflammatory and/or inflammatory lesions, affecting both adolescents and adults. Inflammatory acne lesions are capable to increase their melanin production and promote a post‐inflammatory hyperchromia. Aims: To assess the efficacy of a serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post‐inflammatory hyperpigmentation and controlling skin oiliness in Brazilian patients with acne vulgaris. Patients/Methods: A single‐center, prospective, open‐label clinical study included 42 subjects, from both genders, presenting acne (grade I or II), oily skin and a clinical diagnosis of acne post‐inflammatory hyperpigmentation. The study was conducted for 56 days, with clinical (skin quality and the number of post‐inflammatory hyperchromic lesions) and instrumental (Sebumetry) evaluations after 7, 28, and 56 days of treatment. Standardized pictures were obtained using a VISIA‐6® device. Results: A significant decrease in the grade of post‐inflammatory hyperchromic lesions was observed after 28 and 56 days, while the number of lesions decreases by 29.4% after 56 days (p < 0.001). Sebumetry values showed a significant decrease of 30.7% in the oiliness after 7 days of treatment, and then stable during the study conduction period of 56 days (p < 0.001 for all measurements). Conclusions: The daily treatment using the investigational product showed an interesting decrease both in the grade and the number of post‐inflammatory hyperchromia acne lesions after 56 days, and in the oiliness after 7 days, being stable for all study period. [ABSTRACT FROM AUTHOR]
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- 2021
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6. Quantitative measurement of skin surface oiliness and shine using differential polarized images
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Cynthia L. Nicholson, Henry W. Lim, Amanda F Nahhas, Iltefat H. Hamzavi, Sachin V. Patwardhan, Taylor L. Braunberger, Indermeet Kohli, Scott Kastner, Tasneem F. Mohammad, Mani Thomas, Nikiforos Kollias, and Douglas Canfield
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Future studies ,Materials science ,integumentary system ,Sebum production ,Dermatology ,General Medicine ,Area of interest ,Facial skin ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Skin surface ,medicine ,Contact area ,Mineral oil ,SKIN OILINESS ,Biomedical engineering ,medicine.drug - Abstract
Excess amounts of skin surface oil can lead to adverse psychological consequences. Grease-spot photometry-based techniques measure sebum production rate. However, besides being tedious, these measurements are influenced by contact area, applied pressure, and time of application. Image analysis of polarized images has the potential to provide objective, quantitative information of skin oiliness. This study was designed to set up an imaging device for capturing and enhancing the changes in skin surface oiliness and to clinically and quantitatively, (via image analysis), evaluate varying levels of skin surface oiliness. Mineral oil was used to simulate skin surface oil. 40.5 µL of the mineral oil was applied within a two inch square area of interest on facial skin in twelve steps, from 1 to 40.5 µL, at 40% increments. The results indicate a strong correlation between the quantitative skin surface oiliness measurements and the clinical assessments. This sensitive technique has the potential to be utilized in future studies to evaluate product efficacies in reducing skin oiliness.
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- 2020
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7. The anti‐sebum property of chitosan particles
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Supason Wanichwecharungruang, Natsinee Tangkijngamvong, Punnawich Phaiyarin, and Chanat Kumtornrut
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Sebum secretion ,Chitosan ,medicine.medical_specialty ,Transepidermal water loss ,integumentary system ,business.industry ,Dermatology ,medicine.disease_cause ,Sebum ,030207 dermatology & venereal diseases ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,chemistry ,Skin Physiological Phenomena ,030220 oncology & carcinogenesis ,medicine ,Humans ,Nanoparticles ,Irritation ,business ,Skin ,SKIN OILINESS - Abstract
Background Seborrhea is linked to several medical and mental conditions. Although it is common, effective agents and the standardized sebum level for seborrhea are not elucidated. Aims To determine the efficacy of chitosan particles (CP) formulation on controlling sebum secretion, its extended effects on skin redness and texture after combining with proretinal nanoparticles (CP-PRN), and a correlation of the clinical grading with sebum levels that affect mental health. Patients/methods A four-week clinical trial with forty subjects was conducted. Subjects applied either CP formulation or CP-PRN during nighttime. Objective measurements including sebum levels, transepidermal water loss (TEWL), skin corneometry, skin redness, and texture were analyzed. Subjects completed a self-assessment clinical grading of skin oiliness at every visit. Results Both CP and CP-PRN significantly decreased sebum levels (P ≤ .01) at week 4 compared to baseline. CP also resulted in significant decreases in TEWL (P ≤ .05) and skin corneometry (P ≤ .05) throughout the study. A significant improvement in skin redness was observed with CP-PRN (P ≤ .01). A moderate correlation between the clinical grading and sebum levels was detected (coefficient of 0.5, P ≤ .001), with a sebum level of 106 μg cm-2 indicating emotional discomfort. One subject experienced local irritation with the CP-PRN. Mild pruritic symptoms were reported in both groups. Conclusions Chitosan particles exhibited an interesting anti-sebum effect. It could be combined with PRN to extend benefits without losing the sebum controlling effect. The clinical grading may be useful in practice due to a modest correlation with sebum levels.
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- 2020
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8. Improvements in Acne and Skin Oiliness with Tazarotene 0.045% Lotion in Acne Patients with Oily Skin
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Linda Stein Gold, Eric Guenin, Emil Tanghetti, James Q. Del Rosso, Michael H. Gold, Neil S. Sadick, Leon H Kircik, Fran E Cook-Bolden, and Stephen Tyring
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medicine.medical_specialty ,Tazarotene ,business.industry ,Lotion ,medicine ,medicine.disease ,business ,Dermatology ,Acne ,medicine.drug ,SKIN OILINESS - Abstract
N/A
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- 2021
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9. Systemic treatment of seborrheic dermatitis with retinol palmitate
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V. I. Albanova, V. I. Nozdrin, O. V. Kalinina, and T. A. Belousova
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medicine.medical_specialty ,retinoids ,Erythema ,себорейный дерматит ,efficacy ,sebaceous glands ,лечение ,retinol palmitate ,morphometric study ,seborrheic dermatitis ,сальные железы ,Dermis ,ретиноиды ,Seborrheic dermatitis ,lcsh:Dermatology ,medicine ,Biopsy material ,морфометрия ,гистопатология кожи ,SKIN OILINESS ,treatment ,business.industry ,ретинола пальмитат ,эффективность ,skin histopathology ,lcsh:RL1-803 ,medicine.disease ,Dermatology ,medicine.anatomical_structure ,Scalp ,Retinol palmitate ,medicine.symptom ,business - Abstract
The goal of the study. Evaluating of the effectiveness of treatment of men with a diagnosis «Seborrheic dermatitis of the scalp» by the system using of retinol palmitate. Material and methods. 36 patients every day for 2 months received overnight per os 200000 ME of retinol palmitate, and in the comparison group (39 people) antiseborrheic shampoos have been used. The dynamics of severity of skin oiliness, pruritis, erythema, peeling, infiltration, excoriations has been evaluated in points. Before and after the treatment a histological and morphometric study of biopsy material from the affected areas has been carried.The terms of relapses have been set. Results. Retinol palmitate treatment efficiency - 91.7%, antiseborrheic shampoos - 84.6%. Along with the regression of symptoms of the disease in both groups after retinol palmitate treatment significantly declined oiliness of skin; the sizes of sebaceous glands acini and the presence of differentiated sebocytes, the squares of lymphocytic-macrophage clusters in the dermis, the number of keratinocytes with vacuolated cytoplasm have been reduced. Relapses of the disease during a year occured more rare - in 21 patients out of 32 (in the comparison group- in 25 out of 31) and at a later date (in the first 3 months in 2 patients out of 32, in comparison group in 10 out of 31). Identified effects were due to the action of retinol palmitate on the morphogenesis of the sebaceous glands.
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- 2014
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10. A Validated Questionnaire for Quantifying Skin Oiliness
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Leslie Baumann, Jennifer L. Clarke, Deysi K. Duque, and Randall D. Penfield
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Sebum secretion ,Skin care ,medicine.medical_specialty ,integumentary system ,Skin type ,business.industry ,Sebum production ,Validated questionnaire ,medicine.disease ,Dermatology ,Surgery ,medicine ,business ,Normal skin ,Acne ,SKIN OILINESS - Abstract
Increased sebum production is a common skin complaint and plays an important role in acne and oily scalp conditions. To choose the correct skin care products, which mostly are marketed for dry, oily or normal skin, the consumer must self-assess their skin type. Studies show that individuals incorrectly self-assess their sebum secretion levels. In order to be able to correctly determine skin oiliness, we have developed a six-item skin oiliness scale (SOS) that correlates with sebumeter measurements. The resulting correlation was 0.54, which was significantly different from zero (p is easy to administer questionnaire to accurately determine skin oiliness and can be useful in screening and recruiting patients for research trials, performing outcome research, and recommending skin care products and procedures. Our study shows that this skin oiliness scale is an accurate way to identify and quantify skin oiliness.
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- 2014
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11. Clinical scoring and instrumental analysis to evaluate skin types
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D. G. Mercurio, M. B. A. Demets, P.M.B.G. Maia Campos, and Juliana Hawerroth Segura
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Adult ,Sebum secretion ,Transepidermal water loss ,medicine.medical_specialty ,integumentary system ,Skin type ,business.industry ,Biophysics ,Skin Pigmentation ,Dermatology ,Middle Aged ,Sebum ,medicine.anatomical_structure ,Body Water ,Skin texture ,Skin Physiological Phenomena ,Stratum corneum ,Humans ,Medicine ,Female ,business ,Skin ,Skin imaging ,SKIN OILINESS - Abstract
Summary Background The biology of the skin is very complex, and there are a number of methods used to classify the different skin types. It is possible to measure or quantify the characteristics of the specific skin types, using a variety of techniques that can objectively evaluate the properties of the skin in a noninvasive manner. Aim To clinically characterize different skin types by dermatological evaluation and biophysical and skin imaging techniques, and to evaluate the relationship between the different characteristics. Methods The study recruited 26 volunteers. Clinical scoring was performed by a dermatologist who classified the volunteers' skin as normal or dry (group 1) and combination or oily (group 2). Objective measurements included skin microrelief, pH, oiliness, water content of the stratum corneum and transepidermal water loss (TEWL). Results Positive correlations were found between the level of skin oiliness and skin texture obtained from both instrumental analysis and clinical scoring. The combination and oily skin types had higher clinical scores for shine intensity, oiliness and tendency to pigmentation, and also had higher objective scores for sebum secretion, TEWL and roughness. Conclusions Biophysical and skin imaging techniques are effective tools to help characterize skin type and assist in clinical dermatology. We found that different skin types had different characteristics related to skin microrelief, oiliness and TEWL, and therefore require specific dermatological treatments.
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- 2013
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12. The Efficacy of Korean Herbal Cosmetics for Facial Skin Elasticity
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Younghee Yun, In-Hwa Choi, Ga-Young Cho, and Min-Hee Kim
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Herbal cosmetics ,medicine.medical_specialty ,business.industry ,media_common.quotation_subject ,Assessment instrument ,Cosmetics ,Dermatology ,Facial skin ,Anti wrinkle ,medicine ,medicine.symptom ,business ,Wrinkle ,media_common ,SKIN OILINESS - Abstract
Objective : The purpose of this study was to evaluate the effect of korean herbal cosmetics for facial skin elasticity. Methods : We recruited patients and divided them to cosmetics group and control group randomly. We provided korean herbal cosmetics to cosmetics group and subjects in cosmetics group applied the provided cosmetics for 4 weeks. Control group waited and applied cosmetics that had previously used for 4 weeks. We assessed all subjects in 0 week, 2 weeks and 4 weeks. Primary assessment instrument was moire topography photo scale. Second assessment instrument was skin moisture, oiliness and elasticity which assessed with skintouch system v1.0, detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score. Result : Moire topography photo scale improved in cosmetics group than control group significantly. Skin moisture and elasticity assessed with skintouch system improved in cosmetics group than control group significantly while skin oiliness assessed with skintouch system have not improved significantly. Detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score improved in cosmetics group than control group significantly. Conclusion : Korean herbal cosmetics application might be effective method for facial skin elasticity.
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- 2012
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13. The New Genetico-Racial Skin Classification: How to Maximize the Safety of Any Peel Or Laser Treatment On Any Asian, Caucasian Or Black Patient
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Nabil Fanous, Amanda Fanous, and Valerie Cote
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medicine.medical_specialty ,integumentary system ,business.industry ,Laser treatment ,Skin response ,Bioinformatics ,Skin colour ,Dermatology ,Skin Classification ,medicine ,Original Article ,Surgery ,business ,SKIN OILINESS - Abstract
The popular skin classifications, notably the ‘Fitzpatrick’ and ‘Obaji’ classifications, are primarily based on skin colour. Other criteria are occasionally considered, such as the degree of skin oiliness, thickness, sensibility, etc. Although these classifications are easy to understand and apply, their simplicity limits their precision, sophistication and applicability. The new genetico-racial skin classification proposed herein suggests that skin response to any peel or laser treatment is genetically programmed and is, therefore, linked to the genetic and racial origin of the patient. In other words, in addition to skin colour, the patient's facial features and ancestry should be taken into account when classifying any skin. The new genetico-racial skin classification enables the physician to determine with great precision, and before any peel or laser treatment, the level of the patient's suitability and the expected postoperative outcomes; therefore, reducing the likelihood of complications.
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- 2011
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14. Inter-and intra-individual differences in skin hydration and surface lipids measured with mid-infrared spectroscopy
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Ezerskaia, A., Pereira, S.F., Urbach, Paul, Varghese, B., and Coté, Gerard L.
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integumentary system ,Chemistry ,02 engineering and technology ,Skin integrity ,021001 nanoscience & nanotechnology ,Intra individual ,01 natural sciences ,Mid infrared spectroscopy ,Optical diagnosis ,010309 optics ,Sebum ,Skin hydration ,Skin oiliness ,Skin barrier function ,0103 physical sciences ,Skin surface ,0210 nano-technology ,Spectroscopy ,Biomedical engineering ,SKIN OILINESS - Abstract
Skin health is characterized by heterogeneous system of water and lipids in upper layers providing protection from external environment and preventing loss of vital components of the body. Skin hydration (moisture) and sebum (skin surface lipids) are considered to be important factors in skin health; a right balance between these components is an indication of healthy skin and plays a central role in protecting and preserving skin integrity. In this manuscript we present inter-and intra-individual variation in skin hydration and surface lipids measured with a home-built experimental prototype based on infrared spectroscopy. Results show good agreement with measurements performed by commercially available instruments Corneometer and Sebumeter used for skin hydration and sebum measurements respectively.
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- 2016
15. Infrared spectroscopic measurement of skin hydration and sebum levels and comparison to corneometer and sebumeter
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Ezerskaia, A., Pereira, S.F., Urbach, Paul, Varghese, Babu, Popp, Jürgen, Tuchin, Valery V., Matthews, Dennis L., and Pavone, Francesco S.
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Absorption of water ,Infrared ,Absorption (skin) ,01 natural sciences ,Optical diagnosis ,Sebum-water emulsion ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Skin hydration ,0302 clinical medicine ,Skin oiliness ,Skin surface ,Stratum corneum ,medicine ,Vibrational bands ,Infrared spectroscopy ,integumentary system ,Chemistry ,010401 analytical chemistry ,Skin integrity ,0104 chemical sciences ,Sebum ,medicine.anatomical_structure ,Skin barrier function ,Biomedical engineering - Abstract
Skin health characterized by a system of water and lipids in Stratum Corneum provide protection from harmful external elements and prevent trans-epidermal water loss. Skin hydration (moisture) and sebum (skin surface lipids) are considered to be important factors in skin health; a right balance between these components is an indication of skin health and plays a central role in protecting and preserving skin integrity. In this manuscript we present an infrared spectroscopic method for simultaneous and quantitative measurement of skin hydration and sebum levels utilizing differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lie "in between" the prominent water absorption bands. The skin sebum and hydration values on the forehead under natural conditions and its variations to external stimuli were measured using our experimental set-up. The experimental results obtained with the optical set-up show good correlation with the results obtained with the commercially available instruments Corneometer and Sebumeter.
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- 2016
16. Infrared spectroscopic measurement of skin hydration and sebum levels and comparison to corneometer and sebumeter
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Ezerskaia, A. (author), Pereira, S.F. (author), Urbach, Paul (author), Varghese, Babu (author), Ezerskaia, A. (author), Pereira, S.F. (author), Urbach, Paul (author), and Varghese, Babu (author)
- Abstract
Skin health characterized by a system of water and lipids in Stratum Corneum provide protection from harmful external elements and prevent trans-epidermal water loss. Skin hydration (moisture) and sebum (skin surface lipids) are considered to be important factors in skin health; a right balance between these components is an indication of skin health and plays a central role in protecting and preserving skin integrity. In this manuscript we present an infrared spectroscopic method for simultaneous and quantitative measurement of skin hydration and sebum levels utilizing differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lie "in between" the prominent water absorption bands. The skin sebum and hydration values on the forehead under natural conditions and its variations to external stimuli were measured using our experimental set-up. The experimental results obtained with the optical set-up show good correlation with the results obtained with the commercially available instruments Corneometer and Sebumeter., ImPhys/Optics
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- 2016
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17. Inter-and intra-individual differences in skin hydration and surface lipids measured with mid-infrared spectroscopy
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Ezerskaia, A. (author), Pereira, S.F. (author), Urbach, Paul (author), Varghese, B. (author), Ezerskaia, A. (author), Pereira, S.F. (author), Urbach, Paul (author), and Varghese, B. (author)
- Abstract
Skin health is characterized by heterogeneous system of water and lipids in upper layers providing protection from external environment and preventing loss of vital components of the body. Skin hydration (moisture) and sebum (skin surface lipids) are considered to be important factors in skin health; a right balance between these components is an indication of healthy skin and plays a central role in protecting and preserving skin integrity. In this manuscript we present inter-and intra-individual variation in skin hydration and surface lipids measured with a home-built experimental prototype based on infrared spectroscopy. Results show good agreement with measurements performed by commercially available instruments Corneometer and Sebumeter used for skin hydration and sebum measurements respectively., ImPhys/Optics
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- 2016
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18. Global classification of human facial healthy skin using PLS discriminant analysis and clustering analysis
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J. Latreille, Christiane Guinot, Denis Malvy, and Michel Tenenhaus
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Aging ,integumentary system ,business.industry ,Computer science ,Pharmaceutical Science ,Pattern recognition ,Human skin ,Dermatology ,Linear discriminant analysis ,Facial skin ,Colloid and Surface Chemistry ,Chemistry (miscellaneous) ,Face (geometry) ,Drug Discovery ,Skin Classification ,Partial least squares regression ,Artificial intelligence ,Cluster analysis ,business ,SKIN OILINESS - Abstract
Today's classifications of healthy skin are predominantly based on a very limited number of skin characteristics, such as skin oiliness or susceptibility to sun exposure. The aim of the present analysis was to set up a global classification of healthy facial skin, using mathematical models. This classification is based on clinical, biophysical skin characteristics and self-reported information related to the skin, as well as the results of a theoretical skin classification assessed separately for the frontal and the malar zones of the face. In order to maximize the predictive power of the models with a minimum of variables, the Partial Least Square (PLS) discriminant analysis method was used. The resulting PLS components were subjected to clustering analyses to identify the plausible number of clusters and to group the individuals according to their proximities. Using this approach, four PLS components could be constructed and six clusters were found relevant. So, from the 36 hypothetical combinations of the theoretical skin types classification, we tended to a strengthened six classes proposal. Our data suggest that the association of the PLS discriminant analysis and the clustering methods leads to a valid and simple way to classify healthy human skin and represents a potentially useful tool for cosmetic and dermatological research.
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- 2001
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19. Modulation of sebum excretion from the follicular reservoir by a dichlorophenyl-imidazoldioxolan
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Gérald Pierard and G. Cauwenbergh
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Aging ,integumentary system ,biology ,Chemistry ,Pharmaceutical Science ,Physiology ,Dermatology ,Dandruff ,Hair care ,biology.organism_classification ,Excretion ,Colloid and Surface Chemistry ,medicine.anatomical_structure ,Biochemistry ,Chemistry (miscellaneous) ,Drug Discovery ,Skin surface ,Follicular phase ,medicine ,Forehead ,medicine.symptom ,Cabello ,SKIN OILINESS - Abstract
Synopsis The dichlorophenyl-imidazoldioxolan elubiol is used for skin and hair care in subjects with oily skin or dandruff. A study was conducted in 14 men to evaluate by non-invasive methods the effect of long-term use of elubiol on the sebum output at the skin surface. Measures were made using the Sebumeter SM810 and Sebutapes. Data show a progressive decrease in skin oiliness at the forehead site treated by elubiol compared to the contralateral control site. The function of the follicular reservoir appears to be affected without significant primary change in the sebaceous gland activity.
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- 1996
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20. A preliminary investigation of the impact of oily skin on quality of life and concordance of self-perceived skin oiliness and skin surface lipids (sebum)
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H. Liu, Y. Wu, Y. Niu, Y. Zhen, Didier Saint-Leger, M. Verschoore, and S. Zhong
- Subjects
Adult ,Aging ,medicine.medical_specialty ,Group based ,China ,Younger age ,Pharmaceutical Science ,Dermatology ,Chinese version ,Young Adult ,Colloid and Surface Chemistry ,Age groups ,Quality of life ,Skin Physiological Phenomena ,Surveys and Questionnaires ,Drug Discovery ,Skin surface ,Self perceived ,Medicine ,Humans ,SKIN OILINESS ,Skin ,Gynecology ,integumentary system ,business.industry ,Sebum ,Chemistry (miscellaneous) ,Quality of Life ,Female ,business - Abstract
Synopsis Objective This preliminary study investigated both the impact of oily skin on quality of life (QoL) and the agreement between subjective oily skin self-assessment and objective skin surface sebum measurement in young to middle-aged Chinese women in Beijing. Methods A 18-item Chinese version of the Oily Skin Self-Image Questionnaire (OSSIQ) was used to assess the impact of oily skin on QoL in 300 healthy female subjects (age groups: 20–25; 26–30; 31–35,). The subjects were divided equally into the oily skin group and the non-oily skin group based on their self-perception of skin oiliness. The level of skin surface lipids (SSL) was measured on the middle of the forehead, and both cheeks using the Sebumeter®. In order to assess the agreement between self-perceived skin oiliness and measured SSL, we tentatively used the SSL median value as a dividing point to regroup all subjects. Results The results indicate that the Chinese version of the OSSIQ distinguished the oily skin group from the non-oily skin group. Subjects in the oily skin group had significant higher emotional status score and behavior score when compared with subjects in the non-oily skin group. Subjects in the oily skin group had higher SSL when compared with subjects in the non-oily skin group, especially in younger age groups. The agreement between self-perceived skin oiliness and measured SSL was moderately strong in younger age groups, and declined with age. Conclusion These results strongly suggest that having oily skin can cause a significant negative impact on QoL among Chinese women. The Chinese version of the OSSIQ is a reliable and valid tool for assessing the impact of oily skin on QoL. The accuracy of oily skin self-assessment declines with age. Resume Objectif Cette etude preliminaire visait a quantifier, chez des femmes chinoises jeunes et d'âge moyen, de Pekin, l'impact de leur peau grasse sur leur Qualite de Vie (QoL) ainsi que l'accord entre leur propre perception de leur peau grasse avec les mesures objectives du sebum present en surface. Methodes Une version Chinoise d'un questionnaire (OSSIQ) en 18 points a ete utilise pour apprehender l'impact de la peau grasse sur la QoL de 300 femmmes en bonne sante et de differents ages (groupes: 20–25;26–30;31–35 ans). Les sujets etaient repartis entre “peau non grasse “et “peau grasse” selon leur propres perceptions de ce critere. Les lipides de surface (SSL) ont ete quantifies a l'aide du Sebumeter®, sur le milieu du front et les deux joues. Afin de determiner l'accord possible entre perceptions et valeurs objectives, la valeur mediane des lipides de surface a ete utilisee comme facteur de classement de tous les sujets. Resultats Les resultats indiquent que la version Chinoise du OSSIQ distingue le groupe a peau grasse de celui a peau non grasse. Les sujets a peau grasse montrent des statuts emotionnel et comportemental plus eleves que ceux a peau non grasse. Ils montrent de plus des valeurs de SSL plus elevees que ceux a peau non grasse, surtout dans les groups les plus jeunes. L'accord entre la perception de la peau grasse et les valeurs de SSL est assez eleve chez ces jeunes groups, mais diminue avec l'âge. Conclusion Ces resultats suggerent fortement que la perception d'une peau grasse impacte la QoL de maniere negative, chezles femmes Chinoises etudiees. La version Chinoise du OSSIQ est revele fiable et represente un outil valide pour apprehender l'impact de la peau grasse sur la QoL. La precision de la precision de la peau grasse decline avec l'âge.
- Published
- 2013
21. Oily skin: an overview
- Author
-
Howard I. Maibach and Thais Harumi Sakuma
- Subjects
Sebaceous gland ,Male ,medicine.medical_specialty ,Hot Temperature ,Skin type ,Physiology ,Climate ,Dermatology ,Greasy skin ,Skin hydration ,Sebaceous Glands ,Sex Factors ,Sex factors ,Risk Factors ,medicine ,Animals ,Humans ,SKIN OILINESS ,Skin ,Pharmacology ,Skin care ,integumentary system ,business.industry ,Humidity ,General Medicine ,Skin Care ,Dermatitis, Seborrheic ,Sebum ,medicine.anatomical_structure ,Water barrier ,Female ,business - Abstract
Oily skin (seborrhea) is a common cosmetic problem that occurs when oversized sebaceous glands produce excessive amounts of sebum giving the appearance of shiny and greasy skin. This paper overviews the main concepts of sebaceous gland anatomy and physiology, including the biosynthesis, storage and release of sebum, as well as its relationship to skin hydration and water barrier function. We also address how skin oiliness may vary according to diet, age, gender, ethnicity and hot humid climates. The deeper understanding of this skin type provides the opportunity to better guide patients regarding skin care and also assist in the development of sebosuppressive agents.
- Published
- 2011
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