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To investigate the retention mechanism of N-nitrosodiethanolamine (NDELA) in liquid chromatography, the mobile phase composition was changed on five stationary phases including silica, diol, cyano, amino, and zwitterionic. Afterward, temperature, pH, and buffer concentration effects are studied. Results demonstrate a dual hydrophilic interaction liquid chromatography (HILIC)-reversed phase (RP) mechanism for the retention of NDELA. The transition between the HILIC and RP behavior on a different column, "U-turn" points, was observed between 43 and 68% of water in acetonitrile. The depiction of the natural logarithm of retention factor vs. inverse of the absolute temperature was linear for cyano, amino, and zwitterionic columns. In contrast, it was curvature for silica and diol columns. In each column, the positive slopes indicate a negative retention enthalpy, signifying an exothermic process of transferring analytes from the mobile phase to the stationary phases being examined. In the case of buffer pH and concentration, an ammonium acetate solution with a pH of 5.7 and a concentration of 10 mM was selected for further investigation. Finally, the selectivity of this method in optimal conditions for the analysis of NDELA in shampoo has been investigated. According to the well-obtained selectivity of NDELA in shampoo and the advantages of the HILIC method, this method seems to be a suitable alternative to RP methods. [ABSTRACT FROM AUTHOR]

Background: Hair loss is a widespread health problem that affects numerous individuals and is associated with age, lack of sleep, stress, endocrine problems, and other problems. Caffeine exerts various pharmacological effects, particularly after ingestion. The caffeine‐induced inhibition of phosphodiesterases can increase intracellular cAMP concentrations, ultimately resulting in stimulatory effects on cell metabolism and proliferation. Hence, caffeine has been confirmed to inhibit hair loss caused by premature termination of the hair growth phase. Adenosine also improves hair loss by stimulating hair growth and thickening hair shafts. However, further empirical evidence is required to comprehensively assess the efficacy of hair loss treatment and prevention using a formulation of caffeine and adenosine in specific proportions in shampoos. Objectives: This study aimed to evaluate a shampoo with caffeine and adenosine as a daily scalp care product for hair loss in 77 subjects aged 18–60 years. Methods: The overall and local hair densities were assessed using professional cameras and dermoscopes at different magnifications and distances. Five hairs that came off the participant's head were randomly selected to measure hair diameter. The self‐assessment questionnaires were filled on third month of product use. Results: The combination of caffeine and adenosine in the shampoo significantly enhanced hair density compared to that of the baseline. The results revealed a significant reduction in hair loss. The hair diameters of the subjects did not change significantly. Most of the participants (71.05%) were satisfied with their hair after using the product. Conclusions: Shampoos containing caffeine and adenosine have been demonstrated to exert therapeutic benefits for reducing hair loss. [ABSTRACT FROM AUTHOR]

The ballet industry has long been criticized for using excessively thin and exclusively Anglo-looking ballerinas. The statement that they fit the "look" or comments such as this in the 2015 New York Daily Post: "A lot of people feel ballerinas should all be the same color" (Keivom, 2015) have been used to exclude Black and Brown ballerinas. This chapter describes the relationship between race, gender, and beauty within the ballet industry. It describes the challenges that Black women experience and the anti-Blackness that takes place within ballet due to Eurocentric beauty standards. Through a focus on the emphasis on hair texture, flesh-tone tights, and pointe shoes, and on the racist history of America and ballet, this chapter demonstrates how ballet continues to discriminate against and marginalize Black women. [ABSTRACT FROM AUTHOR]

The racialized gendered body in consumer culture invokes the construction of identities and representation of beauty through embodiment practices. As companies hone in on consumer racial marker distinctions to enhance uniqueness as otherness for profit, an analysis of hair products marketed for Black hair textures provides an opportunity to analyze how products use these at the intersection of race, gender, and beauty. This study uses constructivist grounded theory to analyze the product names and long descriptions for 124 shampoos marketed for Black hair textures on the websites of two major retailers to answer the following questions: What message does the discourse of shampoo product descriptions marketed to Black hair textures communicate about beauty? What message does the discourse of shampoo product descriptions marketed to Black hair textures communicate about Blackness? How does this discourse define the embodiment of Black beauty through hair? The results reveal that the racialized gendered body in consumer culture invokes the construction of identities and representations of beauty through embodiment practices. Through advertisements and product descriptions, beauty companies create ideal images of the lived experiences achieved through consuming beauty products. By constructing visual interpretations of racial signifiers through text, marketing strategies encourage the consumption of otherness, creating a racialized space for Blackness consumption. Combining the five senses with the descriptions of shampoo products marketed for Black hair textures helps us see how beauty embodiment practices reinforce racialized and gendered practices to subjugate the Black body. [ABSTRACT FROM AUTHOR]

Products used for hair care by humans are essential for cleaning, protection, perfuming, and beautification. These are applied directly on the skin and can be a potential factor for dermal exposure to toxic metals. The present research deals with the assessment of heavy metals in the hair care products available in the local markets of Karachi, Pakistan. A total of 20 brands of shampoo and 05 brands of conditioners were collected in triplicate and analyzed for 10 heavy metals (Fe, Mn, Cr, Ni, Cu, Co, Pb, Cd, Zn, and Hg) by atomic absorption spectrophotometer. Toxic metals were found to be higher in conditioner than in shampoo of respective color and brand. Ni and Zn concentrations have exceeded the maximum permissible limits. Consumers belonging to the lower class are more vulnerable to heavy metals exposure because of the high metal content in low-cost products. These results suggested that hair care products should also be considered as one of the sources of heavy metals exposure.

Halal awareness among Muslim consumers has widened to a wide range of products including personal care and cosmetics. Shampoo is the most frequently prescribed treatment for hair and scalp conditions while Centella asiatica and Phyllanthus emblica have been found to have antioxidant properties that exhibit positive benefits on hair. The aim of this study is to develop halal hair growth promoting shampoo containing P. emblica and C. asiatica. Halal certificate, Certificate of Analysis and Material Safety Data Sheet were requested from the suppliers for halal evaluation of the ingredients. Seven shampoo formulations (F1-F7) were created with varying concentrations of P. emblica and C. asiatica extracts, while one formulation was left as a blank. Then, the shampoo formulations underwent an organoleptic evaluation along with other tests for dirt dispersion, pH, solid content, foaming capacity, and stability. The 2,2-diphenyl-1- picrylhydrazyl (DPPH) method was used to measure the antioxidant activity. All of the ingredients used to formulate the shampoo are considered halal based on certificate, origin, and their composition. The evaluation of the shampoo demonstrated that all the formulations exhibited ideal physicochemical properties for hair cleansing and F3 with 4% of C. asiatica extracts and 2% of P. emblica extract produced the best antioxidant activity as it inhibited 92.5% of DPPH. Overall, this study provides the requirement on formulation of halal hair growth promoting shampoo containing P. emblica and C. asiatica. The results show that the formulated shampoo is halal based on document review, exhibited high antioxidant properties for hair growth promoting effect and possess good characteristics as cleansing agent. [ABSTRACT FROM AUTHOR]

SCIENTIFIC RELEVANCE. The high prevalence of fungal skin infections motivates expanding the range of sertaconazole products for external use.AIM. The study was a preclinical comparison of the safety, antifungal activity, and pharmacokinetics of Sertaverin® 2% medicated shampoo (VERTEX JSC, Russia) with those of Sertamicol® 2% solution for external use (Glenmark Pharmaceuticals Ltd, India) and Nizoral® 2% shampoo (Janssen Pharmaceuticals N.V., Belgium) approved in the Russian Federation.MATERIALS AND METHODS. In the toxicity study, the medicinal products were applied to the skin of male and female outbred rats at doses of 0.5 or 1.5 mL/animal for 28 days. The authors evaluated the pharmacokinetics of two sertaconazole formulations (shampoo and solution) following a single administration to adult male rats at the same dose. Nizoral® was not used in the pharmacokinetics study because it contains a different active substance, ketoconazole. The minimum inhibitory concentration (MIC) was determined using the serial microdilution method in a wide range of concentrations.RESULTS. The medicinal products did not exhibit any significant toxic effects in laboratory animals after 28 days of repeated dermal application. Plasma sertaconazole concentrations were negligible. Sertaconazole was intensively distributed in the liver, which is a highly vascularised organ, and in the target organ (skin at the site of application). The relative bioavailability of sertaconazole from the shampoo relative to that from the solution for external use was approximately 30% in liver tissues and approximately 363% in skin tissues at the application site. Sertaverin® was comparable to sertaconazole in the active substance form in terms of inhibiting the growth of Malassezia furfur strains. The MICs calculated on the active substance basis were ≤16–64 μg/mL.CONCLUSIONS. With its synergistic dual mechanism of action, broad-spectrum antifungal activity, lipophilic properties, and low systemic absorption, Sertaverin® may provide a more effective and safe alternative to marketed medicinal products for scalp diseases.

Juan Francisco Mir-Bonafé,1 Jaime Piquero-Casals,2 Ludmila Prudkin,3 Jesus Delgado,3 Julia Santamaria Martínez,3 Vicente Garcia-Patos Briones4 1Department of Dermatology, Hospital Son Llàtzer, Palma de Mallorca, Spain; 2Department of Aesthetic Dermatology and Laser, Dermik, Clínica Dermatológica Multidisciplinar, Barcelona, Spain; 3Innovation and Development, ISDIN, Barcelona, Spain; 4Department of Dermatology, Hospital Vall d’Hebron, Barcelona, SpainCorrespondence: Jaime Piquero-Casals, Department of Aesthetic Dermatology and Laser, Dermik, Clínica Dermatológica Multidisciplinar, Barcelona, Spain, Tel +34 935464710, Email j.piquero@dermik.esBackground: Noninfectious inflammatory dermatoses of the scalp are common, and their symptomsin particular, those affecting appearance, can have a psychological effect that may be disproportionate to their clinical severity. Effective, cosmetically acceptable treatments are important to manage these conditions. Topical corticosteroids form the cornerstone of acute treatment for many of these conditions. We surveyed practicing dermatologists and dermatology residents to determine the current clinical practice in prescribing topical corticosteroids for these disorders in their various preparation formats.Methods: A Delphi method was used, consisting of 2 questionnaire rounds. The first round contained 34 questions and was completed by 612 dermatologists and dermatology residents via email. The first round of responses was analyzed, and points that had > 70% agreement were used to form a second questionnaire of 21 statements. This second round was completed by 346 participants, and their responses were used to generate a final report. Participants were practicing in both public and private practices.Results: Clobetasol propionate 0.05% topical solution was considered to be the most appropriate treatment for noninfectious inflammatory scalp dermatoses in general, with 75.1% agreement in the second round of questionnaire. The main advantages of clobetasol propionate over other topical corticosteroids were reported as potency, effectiveness, and broad action spectrum (94.8% agreement). The preferred pharmaceutical format was the solution of clobetasol propionate.Conclusion: Clobetasol propionate was the preferred topical treatment for the management of scalp dermatoses, usually as first-line treatment; solution was the preferred preparation.Keywords: seborrheic dermatitis, psoriasis, shampoo, topical, solution, clobetasol, scalp, therapy

Amidst a growing shift towards eco-friendly choices in personal care products, the challenge of formulating herbal shampoos with efficacy comparable to synthetic counterparts persists. This study investigates the potential of incorporating patchouli extract and allantoin as additives in anti-dandruff shampoo formulations, assessing their impact on the technological properties of the product. With limited research on their efficacy, our investigation contributes valuable insights to the development of effective and consumer-friendly shampoos targeting dandruff concerns. Physicochemical characteristics (pH, surface tension, texture) were evaluated, alongside specific quality assessments such as wetting time, dirt dispersion, foaming, and cleaning action, in in vivo consumer research. Shampoo formulations incorporating 0.5% Patchoul'Up™ and 1% allantoin exhibited acceptable properties. However, the addition of plant-derived ingredients resulted in a beneficial decrease in surface tension (5.87%). Nevertheless, a decrease in cohesiveness (18%) over a 5-month period resulted in rheological changes, indicating potential instability (p < 0.05). While the consumer evaluation aligns with laboratory findings, continuous research is essential to ensure stability and validate the anti-dandruff potential of the formulation, both in vitro and in vivo. This involves expanding the number of volunteers, with a specific focus on individuals experiencing dandruff concerns, to assess the shampoo's efficacy and impact on diverse user experiences. [ABSTRACT FROM AUTHOR]

Perforation cutters must tackle aggressive corrosion and wear while filling sachets/pouches containing shampoo liquids and conditioners. The present work aims to enhance the durability of the perforation cutters through the application of PVD coatings. Further, this study investigates the role of surface energy and wettability to understand the corrosion behavior of different cutter metallurgies (SS420, D2, and HSS M2) and different coatings in shampoo liquids and conditioners. Two PVD coatings, namely Titanium Nitride (TiN) and Chromium Nitride (CrN), were chosen for this work. The most popular FMCG hair shampoo and conditioner combination in South Asia was selected for the study. The coated cutters were exposed to 20% concentration by volume of different shampoo solutions and their corrosion rates were compared with uncoated cutters. The CrN-coated SS420 specimen exhibited the most significant improvement in corrosion resistance with low wettability compared to all other specimens tested in various solutions. In contrast, the uncoated M2 specimen suffered the most severe corrosion with high wettability in various solutions. An inverse correlation was observed between wettability and corrosion resistance for the various specimens. The findings of this study give a better understanding of the corrosion of perforation cutters by shampoo liquids, elucidating the impact on their longevity and providing insights into the potential benefits of PVD coatings for enhancing their durability.

AbstractSynthetic shampoos that include several chemical components are available in the market. However, the safety and impact of chemical additives are under discussion, because their long-term use may result in hair dryness, scalp irritation, and hair loss. To develop a formulated shampoo as an alternative to synthetic shampoos, this study focused on fabricating a completely natural shampoo comprising Gleditsia sinensis Lam extract (GSW) and Sapindus mukurossi extract (SMW), Gleditsia polysaccharides (SP), cod skin collagen peptide (CSCP), and an essential oil. The influence of the interaction between GSW and SMW, SP, and CSCP components on the foaming performance was investigated using the Ross–Miles method, and the antioxidant activity was analyzed using free radical scavenging. The formulated shampoos were prepared using low-energy emulsification, and their surface tensions were determined using the Wilhelmy plate method. The antibacterial and antifungal activities of the shampoos were revealed by determining the minimum inhibitory and bactericidal concentrations. An interaction assay showed that GSW and SMW exhibited synergistic effects on foaming performance, and SP showed an improved foam stability of GSW. In addition, the antioxidant properties of the mixture (GSW and CSCP) exhibited cooperation. Finally, the optimal formulation of shampoo was GSW (20 wt%) and SMW (20 wt%), CSCP (0.5 wt%), and SP (2 wt%). The shampoo exhibited good foaming performance and decontamination and strong antioxidant, antibacterial, and antifungal activities. [ABSTRACT FROM AUTHOR]

Dandruff is a common scalp condition affecting almost half of the world's population. Despite its high prevalence, the exact pathophysiology is not well established and is understood to be multifactorial, with factors such as fungal colonization, sebaceous gland activity and individual factors being implicated. There is a need for an effective and safe shampoo that can target the above factors. Hence, we have developed a shampoo formulation with properties of oil control, moisturizing, non‐irritative, anti‐fungal, anti‐microbial and itch‐relieving. In this interventional, open‐label study, we evaluated the efficacy and safety of this shampoo in reducing the clinical signs of dandruff and pruritus in patients with pre‐existing mild‐to‐moderate dandruff over a course of 21‐day treatment duration through self‐assessment and objective clinical evaluations. After continued use of the shampoo, there was a significant decrease in the adherent and loose scalp flaking scores. Mean pruritus scores also decreased significantly across the 21‐day time points. There were also no adverse events or skin intolerances reported. This study showed that our shampoo formulation has led to a significant reduction in both adherent and loose scalp flaking and pruritus when used in individuals suffering from mild to moderate dandruff. As such, it is an ideal shampoo, which can be used to effectively control dandruff. [ABSTRACT FROM AUTHOR]

ABSTRAK Latar Belakang: Salah satu masalah yang sering timbul pada kulit kepala adalah pedikulosis kapitis yang disebabkan oleh kutu kepala (Pediculus humanus capitis). Kutu kepala ini akan membuat kepala terasa gatal sehingga terus-menerus menggaruk. Lama-kelamaan, garukan tersebut akan membuat kulit kepala terkelupas sehingga memicu timbulnya masalah lainnya yang bersifat lokal maupun sistemik terutama pada anak dan perempuan. Walaupun kecil, kutu kepala sangat berbahaya, karena hidup dengan menghisap darah dari kulit kepala dan menular dengan mudah ke berbagai tempat, seperti ke bantal, guling, hingga ke kepala manusia. Salah satu cara mengatasi kutu kepala adalah dengan menggunakan pedikulosida sintetis yang mudah didapat di apotek. Tujuan: Untuk mengetahui efektifitas penggunaan sampo dari daun sirsak dalam membasmi kutu kepala. Metode: Penelitian ini merupakan penelitian eksperimental dengan menggunakan kutu kepala sebanyak 72 ekor dengan 3 kali replikasi. Kelompok uji terdiri dari kelompok P1 dengan konsentrasi larutan daun sirsak 15% dan kelompok P2 10%. Sampo P1 dan P2 masing-masing dilakukan pengenceran dengan air dengan perbandingan sampo:air, yaitu 1:1 dan 1:2. Hasil: Waktu yang diperlukan untuk mematikan kutu kepala pada kelompok P1 dengan waktu rata-rata 11 detik pada pengujian sampo:air (1:1) dan 11,67 detik pada (1:2). Adapun kelompok P2 pada pengujian sampo:air (1:1) dalam waktu 12 detik dan 12,33 detik pada (1:2). Persentase mortalitas kutu kepala pada keseluruhan kelompok uji adalah 100% dan pada P2 ratarata 12 detik dengan persentase mortalitas 100%. Kesimpulan: Sampo dari daun sirsak efektif dalam membasmi kutu kepala. Kata Kunci: daun sirsak, kutu kepala, pedikulosis kapitis, sampo ABSTRACT Background: One problem that often arises on the scalp is pediculosis capitis caused by head lice (Pediculus humanus capitis). These head lice will make your head itch and scratching constantly. Over time, the scratching will exfoliate the scalp, triggering other local and systemic problems, especially in children and women. Although small, head lice are very dangerous, because they live by sucking blood from the scalp and spread easily to various places, such as pillows, bolsters, up to the human head. One way to deal with head lice is to use synthetic pediculicides which are easy to get at pharmacies. Objectives: To find out the effectiveness of using soursop leaf shampoo in eradicating hair nails. Methods: This study was an experimental study using 72 head lice with 3 replications. The test group consisted of group P1 with a concentration of 15% soursop leaf solution and group P2 10%. Each of the P1 and P2 shampoos was diluted with water with a shampoo:water ratio, namely 1:1 and 1:2. Results: The time needed to kill head lice in group P1 was 11 seconds on the shampoo:water (1:1) test and 11.67 seconds on (1:2) average. As for the P2 group in the shampoo:water test (1:1) in 12 seconds and 12.33 seconds in (1:2). The percentage of head lice mortality in the entire test group was 100% and at P2 an average of 12 seconds with a mortality rate of 100%. Conclusion: Soursop leaf shampoo is effective in eradicating head lice. Keywords: head lice, pediculosis capitis, shampoo, soursop leaf

Shampooing is a universal daily hair care routine in this modern era. In todays' market, shampoo products have been advertised and commercialized for different purposes and grades like medicated, professional, baby, or regular shampoo for everyday use. These shampoos typically contain a range of core ingredients, such as, surfactants, foaming agents, conditioners, pearlescent agents, sequestrants, pH adjuster, antidandruff agents, colorants, perfumes, and preservatives. Most of these ingredients present in shampoos are synthetically made. For example, diethylamine, triethylamine, cocamide diethanolamine and some other by-products like 1,4-dioxane. Although regulatory agency has controlled the application of these synthetic ingredients in cosmetics, they are still capable of being dermally absorbed and elicit allergic reactions, skin irritation, contact dermatitis below restricted concentrations. Prolonged exposure to these synthetic ingredients is also associated with carcinogenicity and mutagenicity. This review mainly focuses on elucidating the common synthetic ingredients used in the shampoo formulation, their functions and their potential health risks following long term exposure. [ABSTRACT FROM AUTHOR]

Background: Frontal fibrosing alopecia (FFA) is a cicatricial alopecia affecting the frontotemporal hairline. Given that this scarring, immune-mediated follicular destruction most commonly affects postmenopausal Caucasian women, researchers have postulated that there are hormonal and genetic components; however, the etiology of FFA is still unknown. Recently, dermatologists have reported cases of FFA as being potentially caused by cosmetic products, such as sunscreen and shampoo. Therefore, this systematic review and meta-analysis intend to be the first to analyze the relationship between FFA and cosmetic/personal care products and treatments, including sunscreen, moisturizer, foundation, shampoo, conditioner, hair mousse, hair gel, hair dye, hair straightening/rebonding, chemical/laser facial resurfacing, aftershave, and facial cleanser. Methods: The Cochrane, PubMed, EMBASE, and Medline (Ovid) databases were searched for the relevant studies from the date of inception to August 2022. Case–control, cross-sectional, and cohort studies examining the effects of cosmetic/personal care product use on FFA, available in English full-text, were included. Analyses were performed using Review Manager, version 5.4. Results were reported as an odds ratio (OR) with a 95% confidence interval (CI); p values < 0.05 were considered significant. Results: Nine studies were included in our quantitative analyses, totaling 1,248 FFA patients and 1,459 controls. There were significant positive associations found for FFA and sunscreen (OR 3.02, 95% CI 1.67–5.47; p = 0.0003) and facial moisturizer (OR 2.20, 95% CI 1.51–3.20; p < 0.0001) use. Gender sub-analyses demonstrated a positive association for FFA and facial moisturizer in men (OR 5.07, 95% CI 1.40–18.32; p = 0.01), but not in women (OR 1.58, 95% CI 0.83–2.98; p = 0.16). Both gender sub-analyses were significantly positive for the association with facial sunscreen (Male OR 4.61, 95% CI 1.54–13.78, p = 0.006; Female OR 2.74, 95% CI 1.32–5.70, p = 0.007). There was no association found for a facial cleanser (OR 1.14, 95% CI 0.33–1.52; p = 0.51), foundation (OR 1.13, 95% CI 0.83–1.55; p = 0.21), shampoo (OR 0.49, 95% CI 0.22–1.10; p = 0.08), hair conditioner (OR 0.81, 95% CI 0.52–1.26; p = 0.35), hair mousse (OR 1.37, 95% CI 0.75–2.51; p = 0.31), and hair gel (OR 0.90, 95% CI 0.48–1.69; p = 0.74), hair dye (OR 1.07, 95% CI 0.69–1.64; p = 0.77), hair straightening/rebonding (OR 0.88, 95% CI 0.08–9.32; p = 0.92), hair perming (OR 1.41, 95% CI 0.89–2.23; p = 0.14), facial toner (OR 0.51, 95% CI 0.12–2.21; p = 0.37), or aftershave (OR 1.64, 95% CI 0.28–9.49; p = 0.58). Conclusions: This meta-analysis strongly suggests that leave-on facial products, facial sunscreen and moisturizer, are associated with FFA. While the association with facial moisturizer did not persist when stratifying for female populations, gender sub-analyses remained significant for a facial sunscreen. There was no significant relationship found with hair products or treatments. These findings suggest a potential environmental etiology in the development of FFA, particularly UV-protecting chemicals. [ABSTRACT FROM AUTHOR]

We investigated shampoo-related changes in levels of some trace elements in the scalp hair of females and their impact on scalp skin properties. Sixty healthy women divided into control and experimental group who used regular shampoo and Urtica cannabina (U.cannabina) extract shampoo, respectively. Scalp skin was examined using an electronic skin analyzer, and trichometric analysis was performed with a Folliscope. The collected scalp hair samples were digested and measured using inductively coupled plasma-mass spectrometry (ICP-MS). The average copper (p=0.05), zinc (p=0.0002), and iodine (p=0.0004) levels increased notably, whereas the selenium content decreased slightly (p=0.337) in the experimental group. We found that the average iodine content in scalp hair of Mongolian females was three times lower than the global average. The average increase in trace elements may be considered to be due to the transfer of an element into the human scalp during shampooing. These results indicate that some trace elements in human scalp hair are not only associated with nutritional status and environmental factors, but cosmetic products can also affect the trace element composition. The hair growth, diameter, and density gradually increased and were higher in the experimental group than in the control group. Scalp skin moisture, sebum, and pH values increased in the experimental group, whereas the control group showed no notable difference. Herbal extracts may potentially support scalp hair growth and increase the hair density. This ability can be explained by the trace elements in the herbal extract, which may play a key role in inducing hair growth.

Abstract Background The equilibrium of the scalp microbiome is important for maintaining healthy scalp conditions, including sebum secretion, dandruff, and hair growth. Many different strategies to improve scalp health have been reported; however, the effect of postbiotics, such as heat-killed probiotics, on scalp health remains unclear. We examined the beneficial effects of heat-killed probiotics consisting of Lacticaseibacillus paracasei, GMNL-653, on scalp health. Results Heat-killed GMNL-653 could co-aggregate with scalp commensal fungi, Malassezia furfur, in vitro, and the GMNL-653-derived lipoteichoic acid inhibited the biofilm formation of M. furfur on Hs68 fibroblast cells. The mRNA of hair follicle growth factors, including insulin-like growth factor-1 receptor (IGF-1R), vascular endothelial growth factor, IGF-1, and keratinocyte growth factor was up-regulated in skin-related human cell lines Hs68 and HaCaT after treatment with heat-killed GMNL-653. For clinical observations, we recruited 22 volunteer participants to use the shampoo containing the heat-killed GMNL-653 for 5 months and subsequently measured their scalp conditions, including sebum secretion, dandruff formation, and hair growth. We applied polymerase chain reaction (PCR) to detect the scalp microbiota of M. restricta, M. globosa, Cutibacterium acnes, and Staphylococcus epidermidis. A decrease in dandruff and oil secretion and an increase in hair growth in the human scalp were observed after the use of heat-killed GMNL-653-containing shampoo. The increased abundance of M. globosa and the decreased abundance of M. restricta and C. acnes were also observed. We further found that accumulated L. paracasei abundance was positively correlated with M. globosa abundance and negatively correlated with C. acnes abundance. S. epidermidis and C. acnes abundance was negatively correlated with M. globosa abundance and positively correlated with M. restricta. Meanwhile, M. globosa and M. restricta abundances were negatively associated with each other. C. acnes and S. epidermidis abundances were statistically positively correlated with sebum secretion and dandruff, respectively, in our shampoo clinical trial. Conclusion Our study provides a new strategy for human scalp health care using the heat-killed probiotics GMNL-653-containing shampoo. The mechanism may be correlated with the microbiota shift.

Amidst a growing shift towards eco-friendly choices in personal care products, the challenge of formulating herbal shampoos with efficacy comparable to synthetic counterparts persists. This study investigates the potential of incorporating patchouli extract and allantoin as additives in anti-dandruff shampoo formulations, assessing their impact on the technological properties of the product. With limited research on their efficacy, our investigation contributes valuable insights to the development of effective and consumer-friendly shampoos targeting dandruff concerns. Physicochemical characteristics (pH, surface tension, texture) were evaluated, alongside specific quality assessments such as wetting time, dirt dispersion, foaming, and cleaning action, in in vivo consumer research. Shampoo formulations incorporating 0.5% Patchoul’Up™ and 1% allantoin exhibited acceptable properties. However, the addition of plant-derived ingredients resulted in a beneficial decrease in surface tension (5.87%). Nevertheless, a decrease in cohesiveness (18%) over a 5-month period resulted in rheological changes, indicating potential instability (p < 0.05). While the consumer evaluation aligns with laboratory findings, continuous research is essential to ensure stability and validate the anti-dandruff potential of the formulation, both in vitro and in vivo. This involves expanding the number of volunteers, with a specific focus on individuals experiencing dandruff concerns, to assess the shampoo’s efficacy and impact on diverse user experiences.

In recent decades, there has been a growing demand for shampoos derived from botanical sources due to their avoidance of synthetic and highly allergenic chemicals used as bioactives and excipients. These hair care products are free from sulfates, parabens, silicones, synthetic fragrances, and artificial colours. Natural shampoos are sustainable, skin-friendly, and eco-friendly to the environment. Garcinia mangostana (Mangosteen) peel is usually discarded as agricultural waste. It consists of numerous bioactives which exhibit promising activities for hair care and scalp maintenance. This study aimed to formulate and evaluate a novel hair shampoo containing standardised mangosteen peel extract. The formulation of the mangosteen shampoo utilised botanical ingredients and naturally derived components. It underwent an evaluation to assess its physicochemical properties, including visual inspection, pH, surface tension, percentage solid content, wetting time, foam ability and stability, as well as dirt dispersion. These properties were then compared to those of two commercially available hair shampoos. Its antimicrobial activity towards Malassezia furfur ATCC 14521 and Staphylococcus aureus ATCC 25923 was also examined and compared with the commercial shampoo using the microbroth dilution method. Its antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity assay. It was noticed that all formulations (F1–F4) had acceptable physicochemical properties, and they fell within the standard range. F2 had the best antifungal activity (MIC 0.039 mg/mL, MFC 0.156 mg/mL), and moderate antibacterial (MIC 2.50 mg/mL, MBC 5.00 mg/mL) and antioxidant activities (IC50 21.9 ± 3.27 mg/mL; AEAC 26.3 ± 4.06 mg AA/100 g sample). A microscopic examination of hair strands after washing revealed the successful removal of artificial sebum, signifying a good detergency effect. The physical and chemical properties of the hair shampoo formula remained stable without phase separation. In conclusion, the formulated clean hair shampoo with standardised mangosteen peel extract has good cleansing properties, and it is effective in inhibiting dandruff-causing microbial and scavenging free radicals. [ABSTRACT FROM AUTHOR]

A key factor in the prevention of hair loss is the provision of optimal conditions on the scalp. In this regard, reduction of oxidative stress on the scalp is one critical requirement to support the hair follicles to function optimally. Recently, a novel shampoo formulation technology containing anti-oxidants such as piroctone olamine has been demonstrated to improve hair retention based on micellar degradation and coacervation effects. Caffeine has also been shown to exhibit anti-oxidant activity including the ability to inhibit lipid peroxidation. As with piroctone olamine, it is expected that follicular delivery of caffeine will enhance its anti-oxidant activity in a region that will be beneficial for hair retention. In this study, two shampoo formulations as well as a control formulation were applied to the calf area of n = 9 male participants. The technique of differential tape stripping was applied to obtain the caffeine penetrated to the stratum corneum and to the hair follicles. Isotope-dilution liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was performed to demonstrate caffeine follicular delivery from the shampoo formulas. The results showed that the percentage of caffeine recovered in the hair follicles was 8–9% of the caffeine absorbed into the skin and matched an existing caffeine-based shampoo. In conclusion, a novel shampoo formulation technology has been developed that effectively delivers beneficial anti-oxidants to improve hair retention. This new shampoo is expected to be especially useful in the goal of retaining hair during aging. [ABSTRACT FROM AUTHOR]

Greasy hair becomes a major problem to the health of the hair, one of which is dandruff. This is because greasy hair can facilitate the adhesion of dirt. Active charcoal of palm oil shell is activated charcoal having a pore diameter in the range of 1.76 to 1.84 nm and it has been proven that it has absorption ability 2 times higher than commercial activated carbon to absorb the oil in hair. Based on this, active charcoal derived from palm oil shells is processed into cosmetic products. One of the cosmetic products that can be used to overcome hair health problems is shampoo. Shampoo formulations with a variety of concentrations of activated charcoal with palm shell with concentrations of 4% (FI), 8% (FII), 12% (FIII). Then the evaluation of shampoo's physical properties such as organoleptic, pH, homogeneity, viscosity, foam height, specific gravity, foam stability test and cycling test were carried out. In vitro test the effectiveness of the excess oil absorber by using a turbidimetric device. The comparison control used was Pantene shampoo as a positive control and the basis of the shampoo as a negative control. Showed that the higher the concentration of activated charcoal from the coconut shell, the better the ability to absorb excess oil with the largest NTU FIII value of 11,800. The formula that has good physical properties and is stable in storage and has good oil absorption ability is FIII. [ABSTRACT FROM AUTHOR]

The areas where surfactants are used most are the cleaning and cosmetics industry. Among surfactants, anionic surfactants are the main micelle-forming surfactants with the largest production volume and variety. Surfactants used in the cosmetics industry should be used more carefully and in as little amounts as possible when they come into direct contact with humans. In this study, the viscosity and foaming efficiency of anionic surfactants on shampoo were investigated. In this study, the most widely used anionic surfactants in the industry (Sodium Lauryl Sulphate, Sodium Laureth Sulphate and Sodium C14-16 Olefin Sulfonate) were used. These anionic surfactants were added to the prepared shampoo base at certain ratios. The viscosity values were measured by adding 0.5-2% NaCl to the shampoos with anionic surfactant added. Foam tests of shampoo bases with anionic surfactant added were carried out. According to the results obtained, it has been determined that the anionic surfactant, which has the ideal viscosity value and the best foaming property by using the least amount, is Sodium Lauryl Sulphate. [ABSTRACT FROM AUTHOR]

Goat milk, per se, has very interesting technological and nutritive features, and could be used in shampoo formulations and improve their properties. The aim of this study was to compare the physicochemical characteristics and conditioning performance of shampoo made with 0, 10, 20 and 30% content of goat milk. pH, surface tension, solids content, wetting time, foaming ability and foam stability, dirt dispersion, viscosity, instrumental colour, and conditioning performance were evaluated during 60 days of storage. pH ranged between 5.55 and 6.73. Goat milk addition decreased the surface tension and viscosity, as well as provided good conditioning performance, good cleaning capacity, foaming stability, wetting time, luminosity and blueish to the shampoos. The best shampoos were those that used 10–20% of goat milk, because they kept their features and did not present flocculation of milk proteins or acidification. The stability of the product with goat milk was established at one month.

Hair loss is caused by different factors, and it could be cause of emotional stress in people who present it. The objective of incorporating beef marrow into a hair product as an auxiliary ingredient against hair loss, it was decided to carry out a market study out to specify the characteristics of the shampoo to be developed. Twenty-five formulations with different percentages of beef marrow were elaborated, finally one of them was selected and analyzed to determine its physicochemical characteristics. Two batches were made, one pink with a rose aroma and the other yellow with a citrus aroma, to evaluate by means of an affective sensory acceptance test the degree of effectiveness of the product in comparison with the base shampoo. The sample size was 55, 54 % perceived a decrease in hair loss, suggesting that beef marrow incorporated into a shampoo has an effect against alopecia. [ABSTRACT FROM AUTHOR]

Background: The equilibrium of the scalp microbiome is important for maintaining healthy scalp conditions, including sebum secretion, dandruff, and hair growth. Many different strategies to improve scalp health have been reported; however, the effect of postbiotics, such as heat-killed probiotics, on scalp health remains unclear. We examined the beneficial effects of heat-killed probiotics consisting of Lacticaseibacillus paracasei, GMNL-653, on scalp health. Results: Heat-killed GMNL-653 could co-aggregate with scalp commensal fungi, Malassezia furfur, in vitro, and the GMNL-653-derived lipoteichoic acid inhibited the biofilm formation of M. furfur on Hs68 fibroblast cells. The mRNA of hair follicle growth factors, including insulin-like growth factor-1 receptor (IGF-1R), vascular endothelial growth factor, IGF-1, and keratinocyte growth factor was up-regulated in skin-related human cell lines Hs68 and HaCaT after treatment with heat-killed GMNL-653. For clinical observations, we recruited 22 volunteer participants to use the shampoo containing the heat-killed GMNL-653 for 5 months and subsequently measured their scalp conditions, including sebum secretion, dandruff formation, and hair growth. We applied polymerase chain reaction (PCR) to detect the scalp microbiota of M. restricta, M. globosa, Cutibacterium acnes, and Staphylococcus epidermidis. A decrease in dandruff and oil secretion and an increase in hair growth in the human scalp were observed after the use of heat-killed GMNL-653-containing shampoo. The increased abundance of M. globosa and the decreased abundance of M. restricta and C. acnes were also observed. We further found that accumulated L. paracasei abundance was positively correlated with M. globosa abundance and negatively correlated with C. acnes abundance. S. epidermidis and C. acnes abundance was negatively correlated with M. globosa abundance and positively correlated with M. restricta. Meanwhile, M. globosa and M. restricta abundances were negatively associated with each other. C. acnes and S. epidermidis abundances were statistically positively correlated with sebum secretion and dandruff, respectively, in our shampoo clinical trial. Conclusion: Our study provides a new strategy for human scalp health care using the heat-killed probiotics GMNL-653-containing shampoo. The mechanism may be correlated with the microbiota shift. [ABSTRACT FROM AUTHOR]

With the increased demand for sustainable, hypoallergenic products, plant surfactants are a promising, eco-friendly option for cleaning products due to their low toxicity or even the absence of toxicity. In the present study, surfactant-rich extracts from Chenopodium quinoa, Glycine max, and Malpighia emarginata were assessed for their stability, antioxidant capacity, toxic potential, and cleaning potential in shampoo formulations. The surfactants in the extracts were isolated and characterized by NMR, UV-Vis, and FTIR spectroscopy. The results demonstrated that the extracts remained stable within the temperature and pH ranges tested. The antioxidant properties were also determined. In the analysis of irritation potential, G. max and C. quinoa exhibited low toxicity and no toxicity, respectively. The cleaning potential analysis confirmed that the extracts could be used as primary surfactants. Seven shampoo formulations were developed, which showed potential to reduce surface tension to the range of 27.1–31.7 mN/m and interfacial tension to the range of 5.4–7.3 mN/m. The wettability, percentage of solids, density, pH, and dirt dispersion of the formulas were within standard ranges, and the sebum removal capacity of the seven formulations was similar to or even better than that of a commercial shampoo. [ABSTRACT FROM AUTHOR]

The components of a shampoo are selected specifically to carry out important roles within the formulation. They must be carefully considered as not only do they act to carry out their own function but they also influence the function of the other components through complexation and other physiochemical interactions. This review focuses on the four principal components in a commercial shampoo formulation: surfactant, deposition polymer, structuring polymer, and viscosity modifiers. The most common molecule types used commercially to carry out the specific roles are discussed, with each of their fundamental functions outlined in detail. The mechanisms by which these molecules can perform these roles are reviewed. Further consideration is taken to outline how components could interact with one another to hinder or facilitate processes. [ABSTRACT FROM AUTHOR]

Simple Summary: Greasy skin and excessive skin scaling accompany numerous dermatoses. Rapid and sustainable improvement of skin appearance and application practicability are important features to enhance the dog's appearance and encourage owner compliance. The study aimed to evaluate the tolerance and performance of one shampoo and subsequent mousses applications containing plant extracts in dogs with greasy skin. Six dogs were washed with plain water on day (D)0 and served as negative controls. Twelve dogs were shampooed on D0 and received eight mousse applications at 48–72 h intervals from D2 to D18. Skin was evaluated on D0, D0 + 4 h, D7, D14 and D24. At baseline, there were no significant differences observed between groups. In the control group, skin appearance and lipid contents remained stable throughout the study. Skin lesions and malodour were significantly reduced in the test group from D7 with no side effects. Hydration and hair lipids levels decreased in the test group at D0 + 4 h and returned to baseline from D14 and D7 on, respectively. In conclusion, one shampoo and subsequent mousse applications rapidly and safely improved coat and skin appearance in dogs with greasy skin and dandruff without affecting water and hair lipid contents. The study aimed to evaluate the tolerance, performance and effect on hair lipids and skin hydration of a protocol combining applications of one shampoo and subsequent mousses containing plant extracts (Ophytrium and Seboliance) in dogs with an undiagnosed chronic greasy keratinisation disorder. Six dogs were washed with plain water on day (D)0. Twelve dogs were shampooed on D0 and received eight mousse applications at 48–72 h intervals from D2 to D18. Clinical score (CS), Natural Moisturizing Factors (NMF) and hair lipids (HL) were evaluated on D0, D0 + 4 h, D7, D14 and D24. At baseline, no significant differences were observed in CS, NMF and HL between groups. In the control group, CS and HL remained stable throughout the study while a slight decrease in NMF was observed at D0 + 4 h. CS was significantly reduced in the test group between D0 and D7 (−53%) which reached 91% at D24 (p < 0.05), with no side effects. NMF levels decreased in the test group at D0 + 4 h (−73%, p < 0.0001) and returned to baseline from D14. In conclusion, one shampoo and subsequent mousse applications rapidly and safely improved coat quality in dogs with an undiagnosed keratinisation disorder without affecting NMF and HL contents over the study period. [ABSTRACT FROM AUTHOR]

Dandruff is a dermatological, harmless, noninflammatory, chronic scalp condition caused by Malassezia species and recognisable by the white flakes of dead skin in the hair. Mannosylerythritol lipids (MEL) are non-ionic glycolipid surfactants (biosurfactants) with excellent surface-active properties. Their skin compatibility, biocompatibility, biodegradability and remarkable antimicrobial properties make them a potential alternative to conventional surfactants. In the current study, an anti-dandruff shampoo was formulated with different concentrations of sodium lauryl sulphate (SLS) and MEL as surfactants. Two anti-dandruff agents, salicylic acid and benzoic acid, were used. The other ingredients used were xanthan gum, sodium EDTA, urea, Tween 80 and distilled water. The various physicochemical parameters evaluated were colour, clarity, odour, texture, pH, skin irritation, percentage of solid content, dispersibility for dirt, foam formation and foam stability, critical micelle concentration, washability, surface tension, visual stability and antimicrobial test using recommended procedures. The pH ranged from 5.15 to 6.5, the physical appearance was golden yellow, the solids content ranged from 25.1% to 28%, surface tension ranged from 30.64 mN m-1 to 38.00 mN m-1, CMC concentration ranged from 30.14 g/L to 30.16 g/L and foam value ranged from 190 mL to 105 mL. Antimicrobial activity was determined with Staphylococcus aureus (DSM 3463) and Malassezia furfur (ATCC14521). The zone of inhibition ranged from 10 mm to 17 mm (S. aureus) and 14.5 mm to 24 mm (M. furfur), respectively. The shampoo formulated with MEL only (formulation C) showed lower foaming and anti-dandruff activity than the synthetic shampoo (formulation A). However, the anti-dandruff activity increased when MEL was used in combination with SLS (formulation B). This shows that the antimicrobial properties of MEL and SLS together with other antimicrobial agents such as salicylic acid and benzoic acid enhance the properties of the shampoo. SLS can be completely replaced by a combination with biosurfactants to reduce the use of chemical surfactants and improve the anti-dandruff properties. [ABSTRACT FROM AUTHOR]

We investigated shampoo-related changes in levels of some trace elements in the scalp hair of females and their impact on scalp skin properties. Sixty healthy women were divided into the control and experimental groups who used regular shampoo and Urtica cannabina L. (U. cannabina) extract shampoo, respectively. Scalp skin was examined using an electronic skin analyzer, and trichometric analysis was performed with a Folliscope. The collected scalp hair samples were digested and measured using inductively coupled plasma-mass spectrometry (ICP-MS). The average copper (p = 0.05), zinc (p = 0.0002), and iodine (p = 0.0004) levels increased notably, whereas the selenium content decreased slightly (p = 0.337) in the experimental group. We found that the average iodine content in the scalp hair of Mongolian females was three times lower than the global average. The average increase in trace elements may be considered to be due to the transfer of an element into the human scalp during shampooing. These results indicate that the composition of some trace elements in human scalp hair is affected not only by nutritional status and environmental factors but also by cosmetic products. The hair growth, diameter, and density gradually increased and were higher in the experimental group than in the control group. Scalp skin moisture, sebum, and pH values increased in the experimental group, whereas the control group showed no notable difference. Herbal extracts may potentially support scalp hair growth and increase the hair density. This ability can be explained by the trace elements in the herbal extract, which may play a key role in inducing hair growth. [ABSTRACT FROM AUTHOR]

Goat milk, per se, has very interesting technological and nutritive features, and could be used in shampoo formulations and improve their properties. The aim of this study was to compare the physicochemical characteristics and conditioning performance of shampoo made with 0, 10, 20 and 30% content of goat milk. pH, surface tension, solids content, wetting time, foaming ability and foam stability, dirt dispersion, viscosity, instrumental colour, and conditioning performance were evaluated during 60 days of storage. pH ranged between 5.55 and 6.73. Goat milk addition decreased the surface tension and viscosity, as well as provided good conditioning performance, good cleaning capacity, foaming stability, wetting time, luminosity and blueish to the shampoos. The best shampoos were those that used 10–20% of goat milk, because they kept their features and did not present flocculation of milk proteins or acidification. The stability of the product with goat milk was established at one month. [ABSTRACT FROM AUTHOR]

Brassica juncea (L.) Czern. leaves have been ethnomedicinally used by the people of Assam for getting rid of Pediculosis capitis (lice infestations) since time immemorial. Pediculosis capitis is a widely occurring and highly transferable condition affecting millions worldwide. Both pharmacological and non-pharmacological approaches are utilized to get rid of this condition, but with the advent of lice becoming resistant to most chemical anti-lice agents, researchers are turning towards herbal alternatives. This current study is devoted to establish the potential present in Brassica juncea against this parasite and to use it when currently prevalent pediculocides fails to combat the parasite. In addition to this, a laboratory-based shampoo is formulated to provide an aesthetic, reliable, safe and patient friendly medium to deliver the agent. Lastly both the extract and the medicated shampoo are tested on lice following a definite protocol and the results are compared to that of a marketed formulation. [ABSTRACT FROM AUTHOR]

Copyright of China Surfactant Detergent & Cosmetics (1001-1803) is the property of China Surfactant Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Medical professionals that treat patients with alopecia usually lack knowledge about hair cosmetics. Trichologists focus on hair cycling and growth problems and not on the hair shaft integrity. This may lead to abandon of the use of the prescribed treatment, such as topical minoxidil or to inadequate traumatic grooming habits that may jeopardize hair follicle health. Shampoos, hair dyes, and hair-straightening products may alter hair fiber structure, remove lipids, and elude protein. Hair procedures such as hair dying and straightening have side effects and health concerns, especially for pregnant women or sensitive hair and scalp patients. Hair breakage, follicle traction, frizz, contact dermatitis, and mutagenicity are possible side effects of hair cosmetics misuse. The proper use of hair care products may help to increase patients' adherence to alopecia treatments and avoid health problems related to inadequate application of hair cosmetics and procedures.

In recent decades, there has been a growing demand for shampoos derived from botanical sources due to their avoidance of synthetic and highly allergenic chemicals used as bioactives and excipients. These hair care products are free from sulfates, parabens, silicones, synthetic fragrances, and artificial colours. Natural shampoos are sustainable, skin-friendly, and eco-friendly to the environment. Garcinia mangostana (Mangosteen) peel is usually discarded as agricultural waste. It consists of numerous bioactives which exhibit promising activities for hair care and scalp maintenance. This study aimed to formulate and evaluate a novel hair shampoo containing standardised mangosteen peel extract. The formulation of the mangosteen shampoo utilised botanical ingredients and naturally derived components. It underwent an evaluation to assess its physicochemical properties, including visual inspection, pH, surface tension, percentage solid content, wetting time, foam ability and stability, as well as dirt dispersion. These properties were then compared to those of two commercially available hair shampoos. Its antimicrobial activity towards Malassezia furfur ATCC 14521 and Staphylococcus aureus ATCC 25923 was also examined and compared with the commercial shampoo using the microbroth dilution method. Its antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity assay. It was noticed that all formulations (F1–F4) had acceptable physicochemical properties, and they fell within the standard range. F2 had the best antifungal activity (MIC 0.039 mg/mL, MFC 0.156 mg/mL), and moderate antibacterial (MIC 2.50 mg/mL, MBC 5.00 mg/mL) and antioxidant activities (IC50 21.9 ± 3.27 mg/mL; AEAC 26.3 ± 4.06 mg AA/100 g sample). A microscopic examination of hair strands after washing revealed the successful removal of artificial sebum, signifying a good detergency effect. The physical and chemical properties of the hair shampoo formula remained stable without phase separation. In conclusion, the formulated clean hair shampoo with standardised mangosteen peel extract has good cleansing properties, and it is effective in inhibiting dandruff-causing microbial and scavenging free radicals.

A key factor in the prevention of hair loss is the provision of optimal conditions on the scalp. In this regard, reduction of oxidative stress on the scalp is one critical requirement to support the hair follicles to function optimally. Recently, a novel shampoo formulation technology containing anti-oxidants such as piroctone olamine has been demonstrated to improve hair retention based on micellar degradation and coacervation effects. Caffeine has also been shown to exhibit anti-oxidant activity including the ability to inhibit lipid peroxidation. As with piroctone olamine, it is expected that follicular delivery of caffeine will enhance its anti-oxidant activity in a region that will be beneficial for hair retention. In this study, two shampoo formulations as well as a control formulation were applied to the calf area of n = 9 male participants. The technique of differential tape stripping was applied to obtain the caffeine penetrated to the stratum corneum and to the hair follicles. Isotope-dilution liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was performed to demonstrate caffeine follicular delivery from the shampoo formulas. The results showed that the percentage of caffeine recovered in the hair follicles was 8–9% of the caffeine absorbed into the skin and matched an existing caffeine-based shampoo. In conclusion, a novel shampoo formulation technology has been developed that effectively delivers beneficial anti-oxidants to improve hair retention. This new shampoo is expected to be especially useful in the goal of retaining hair during aging.

Copyright of Bilecik Seyh Edebali University Journal of Social Sciences is the property of Bilecik Seyh Edebali University Journal of Social Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Diversification of products that are derived from essential oils carries important implications in reducing agricultural waste and promoting the medicinal materials industry. In this study, we formulated a shampoo and a body wash product incorporated with lemongrass (Cymbopogon citratus) essential oils (LEOs) and evaluated their color stability and the LEO compositional change. We first determined the color change and chemical composition of bare LEO under different storage conditions. Afterward, the washing product base was formulated, and its formulation process was optimized to minimize the color change by varying a wide range of parameters including pH, the inclusion of preservatives and antioxidants, LEO/antioxidant ratio, and emulsification temperature. The base product was then used in body wash and shampoo formulation following our previously reported procedure. The results indicated that direct incorporation of the LEO into the cosmetic products resulted in better color stability and citral retention in comparison with emulsion formation. In addition, shampoo and body wash products showed no detectible presence of compounds resulting from citral decomposition such as 3,7-dimethyl-1,3,6-octatriene, p-mentha-1,5-dien-8-ol, and p-cymene-8-ol. The current findings are expected to aid in diversifying LEO-derived commodities and justifying scalability of the cosmetics production process with a focus on the incorporation of naturally derived ingredients.

Shampoos are daily care products designed to clean the hair and scalp. The aim of this study was to compare the contents of baby and newborn shampoos sold in supermarkets and pharmacies, determine the levels of substances reported to be dangerous to babies and newborns health in these shampoos. This cross-sectional study included 18 newborn and baby shampoos that families could buy at supermarkets and pharmacies in Turkey. For newborn and baby shampoos, the number of preservative substances have been determined. A total of 68 chemicals was found in these 18 shampoos, with an average of 14.83 ± 2.43 chemicals in each shampoo. Most of these chemicals were not recommended for use in children. Shampoos that contain numerous chemicals and substances confirmed to be harmful or have suspicious effects should not be recommended. It is clear that more studies are needed in this under-researched area. [Med-Science 2021; 10(2.000): 334-7]

Products used for hair care by humans are essential for cleaning, protection, perfuming, and beautification. These are applied directly on the skin and can be a potential factor for dermal exposure to toxic metals. The present research deals with the assessment of heavy metals in the hair care products available in the local markets of Karachi, Pakistan. A total of 20 brands of shampoo and 05 brands of conditioners were collected in triplicate and analyzed for 10 heavy metals (Fe, Mn, Cr, Ni, Cu, Co, Pb, Cd, Zn, and Hg) by atomic absorption spectrophotometer. Toxic metals were found to be higher in conditioner than in shampoo of respective color and brand. Ni and Zn concentrations have exceeded the maximum permissible limits. Consumers belonging to the lower class are more vulnerable to heavy metals exposure because of the high metal content in low-cost products. These results suggested that hair care products should also be considered as one of the sources of heavy metals exposure. [ABSTRACT FROM AUTHOR]

Copyright of China Surfactant Detergent & Cosmetics (1001-1803) is the property of China Surfactant Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The present study investigated the preparation of anti-dandruff shampoo formulated with goldfish scale containing chitosan as a bioactive compound of the product. The resulting chitosan is analyzed using FT-IR (Fourier Transform Infrared) spectroscopy to examine the functional groups before being transformed into nano chitosan by an ionic gelation process. Physicochemical properties of the product were evaluated including organoleptic test, pH, foam stability, viscosity, and antifungal activity. The results demonstrated that the formulated shampoo (3 g of chitosan) displayed a high inhibition of Candida albicans (27.30 ± 0.98 mm) with acceptable physical properties for commercial products. [ABSTRACT FROM AUTHOR]