1. Advances in the Study of Lynch Syndrome Associated Endometrial Cancer
- Author
-
LIU Xiao, LI Yulan, MA Xing, and XU Feixue
- Subjects
lynch syndrome ,endometrial cancer ,sentinel cancer ,mismatch repair gene ,screening ,Medicine - Abstract
Lynch syndrome (LS), an autosomal dominant genetic disorder caused by mismatch repair gene defects, is characterized by the susceptibility to multi-system malignancies. LS associated endometrial cancer (LS-EC) is the most common extraintestinal sentinel cancer of LS. In the era of precision medicine, early screening of LS-EC is of great significance to preventing the occurrence of other LS related malignant tumors. This paper reviews the research progress on screening methods and prevention of LS-EC, in order to provide reference for precise diagnosis and prevention of LS-related tumors.
- Published
- 2023
- Full Text
- View/download PDF