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2 results on '"real world."'

1. Antithrombotic prophylaxis of atrial fibrillation in an Italian real-world setting: a retrospective study

Author

Ermini G, Perrone V, Veronesi C, Degli Esposti L, and Di Pasquale G

Subjects
atrial fibrillation, oral anticoagulant, antiplatelet agents, general practitioner, real world., Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Giuliano Ermini,1 Valentina Perrone,2 Chiara Veronesi,2 Luca Degli Esposti,2 Giuseppe Di Pasquale3 On behalf of the GP Group 1General Practice, Bologna, Italy; 2CliCon S.r.l. Health, Economics and Outcomes Research, Ravenna, Italy; 3Department of Cardiology, Maggiore Hospital, Bologna, Italy Objectives: The aims of this study were to assess the prevalence of diagnosed atrial fibrillation (AF), the drug use in patients with AF in terms of antithrombotic (AT) strategies used and the compliance with treatment, and to describe the characteristics of patients affected by AF in relation to treatment. Methods: The data collected were provided from databases of general practitioners (GPs) of the Local Health Unit of Bologna in Italy. From January 1, 2009, to December 31, 2012, all subjects aged ≥18 years followed by the 44 GPs enrolled in the study were evaluated, and the subjects with a diagnosis of AF were included in the analysis. Results: From 2009 to 2012, we identified 1,413 patients with a diagnosis of AF (2.09% of 67,517 patients of the 44 GPs). A total of 1,413 patients with a diagnosis of AF (2.09% of 67,517 patients of the 44 GPs) were enrolled in the study. During the study, 14% of the enrolled patients did not receive any prescription of ATs, 30% and 39.56% were treated only with antiplatelet (AP) agents and oral anticoagulants (OACs), respectively, and 16.28% of the patients received prescriptions for both an OAC and an AP agent; of the patients receiving prescriptions for both, only 4.17% received these therapies at the same time. Among the OAC users, the percentage of patients still on treatment with the index drug during the last 3 months of observation was 76.9%. Conclusion: Our findings emphasize that in an Italian real-world setting, the burden of AF in general population from a public health point of view underscores the need for improvement in utilization of appropriate ATs in patients with known AF. Keywords: atrial fibrillation, oral anticoagulant, antiplatelet agents, general practitioner, real world

Published
2017

2. Fractures Between an Online and Offline Community (and the Ethical Responses)

Author

Green, Lelia Rosalind, Green, Lelia Rosalind, Costello, Leesa Narelle, Green, Lelia Rosalind, Green, Lelia Rosalind, and Costello, Leesa Narelle

Abstract

This paper addresses a high-stakes dispute over some six to eight months between two groups of community 'members' which led to official proceedings, social welfare investigations, psychological assessments, indications of a suicide risk and, unsurprisingly, extensive Ethics Committee involvement. The use of the word 'members' in inverted commas highlights the fact that many of the parties to the dispute resigned their membership from the community during the dispute – possibly because they were unhappy at the research team's reluctance to take sides, possibly so that they could continue the conflict beyond the purview and chastisement of administrators and researchers. Two others were removed from the group as part of the research team's duty of care because of the perceived impact of the dispute upon their health and well-being. This may have inadvertently raised the stakes. Overall, the fraught incursions of the virtual world into the real world are an important part of the research findings with respect to this experimental online community.

Published
2009

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