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This study evaluated the level of knowledge among parents in Jazan, Saudi Arabia, regarding substances that can harm child development. The Prevention of Toxic Chemicals in the Environment for Children Tool (PRoTECT) was used for this assessment. A cross-sectional survey using a multi-stage cluster random sampling approach was undertaken among 424 parents who were enlisted from eight primary healthcare centers (PHCCs). The PRoTECT score's median value was 72 out of 90, suggesting a generally high level of awareness. The study found that individuals with higher education, particularly those with postgraduate degrees, had greater awareness of protecting their children's health. Interestingly, unemployed individuals and those residing in mountainous areas also demonstrated higher awareness, possibly due to having more time to focus on their children's health and well-being. Most participants (68.2%) acknowledged the correlation between exposure to toxic chemicals during pregnancy and early childhood, and the subsequent development of neurodevelopmental disorders. The study found a solid foundation of knowledge, with 85.1% of participants interested in learning more about reducing children's exposure, but it also stressed the need for specific actions to turn awareness into prevention. These findings would help policymakers develop effective strategies, such as targeted educational campaigns, collaboration with healthcare providers, utilization of media channels, and encouragement of community-led initiatives, to reduce children's exposure to developmental toxicants in line with national and global environmental health initiatives. Future research should focus on longitudinal consciousness and behavior evaluations and regional environmental contaminants. [ABSTRACT FROM AUTHOR]

Aim of the study: Polymorphisms of DNA repair enzyme gene may alter the ability of damage repair, ischemic stroke susceptibility and outcome. This study aimed to explore the association of polymorphisms in PARP1 and the effects of interactions between genes in Chinese.Materials and methods: A total of 500 patients and 500 healthy controls were enrolled for genotyping. Results: Clinical information analysis revealed higher levels of alcohol and smoking exposure in patients with ischemic stroke, as well as chronic conditions such as diabetes, hypertension, and higher serum triglycerides concentration. In addition, Polymorphism in PARP1 rs8679 was significantly associated with the decreased ischemic stroke risk. Patients harboring the PARP1 rs8679 AG/GG genotype had a better initial stroke, and as for the mRNA level of PARP1, it was suppressed with mutant genotype in comparison with the wild genotype. Finally, the suppressed of PARP1 was induced by gain-binding ability of miR-124-5p through 3'UTR directly binding.Conclusions: In conclusion, our study demonstrates that the SNP rs8679 in PARP1 3′-UTR might act as a protective factor for the outcome of patients with ischemic stroke. [ABSTRACT FROM AUTHOR]

The occupational hazards faced by maxillofacial surgeons are a significant concern, encompassing exposure to infectious diseases, musculoskeletal injuries, radiation, and needle stick injuries. These hazards pose risks to the health and well-being of the surgeons, potentially impacting their ability to provide high-quality patient care. The article comprehensively addresses these occupational risks and emphasizes the importance of implementing robust infection control measures, prioritizing ergonomics in the workplace, and promoting a culture of self-care within the profession. Additionally, it highlights the need for comprehensive training on infection control practices, radiation safety measures, and proper ergonomics to mitigate these hazards effectively. This article provides a comprehensive overview of the occupational hazards faced by maxillofacial surgeons and the measures necessary to ensure their well-being while continuing to deliver essential care to their patients.

In 2023, 16 species were recorded on the territory of the Basitchay Reserve in winter, while 21 species in summer. 93.6% of the Reserve's territory is occupied by forest-shrub and meadow habitats. This also created conditions for abundance of dendrophilous and seed and chick-eating species on the territory. The dominant species of the ornithocomplex are birds belonging to the order of sparrows. The non-registration of the Falcons, Storks and Herons, inhabiting on the territory of the Reserve, as well as their nesting sites, is connected with the mass cutting down of tall sycamore trees during the occupation. As a result, these birds were deprived of breeding conditions. [ABSTRACT FROM AUTHOR]

Background: The accumulation of age‐associated cognitive deficits can lead to Mild Cognitive Impairment (MCI) and dementia. This is a major public health issue for the modern ageing population, as it impairs health, independence and overall quality of life. Keeping the brain active during life has been associated with an increased cognitive reserve, therefore reducing the risk of cognitive impairment in older age. Previous research has identified a potential relationship between musicality and cognition. Objectives: Explore the relationship between musicality and cognitive function in a large cohort of older adults. Methods: This was a nested study within the PROTECT‐UK cohort, which collects longitudinal computerised assessments of cognitive function in adults over 40. Participants were invited to complete the validated Edinburgh Lifetime Musical Experience Questionnaire (ELMEQ) to assess their musical experience and lifetime exposure to music. Linear regression analysis was performed using cognitive data from PROTECT‐UK. Results: Analysis identified an association between musicality and cognition in this cohort. Playing a musical instrument was associated with significantly better performance in working memory and executive function. Significant associations were also found between singing and executive function, and between overall musical ability and working memory. Conclusions: Our findings confirm previous literature, highlighting the potential value of education and engagement in musical activities throughout life as a means of harnessing cognitive reserve as part of a protective lifestyle for brain health. Key points: Playing a musical instrument was associated with significantly better working memory and executive function.Singing and overall musical ability was associated with more favourable cognition.Engagement with musical activities should be considered as part of public health initiatives to promote a protective lifestyle for brain health. [ABSTRACT FROM AUTHOR]

Minister of Empowerment of Women and Children No. 11 of 2011 concerning childfriendly City/District Policy is part of a government policy that aims to protect children in all aspects of life. Child-friendly districts/cities (KLA) are those that have a development system based on children’s rights through the integration of government, community, and business commitments and resources that are planned comprehensively and sustainably in policies, programs, and activities to ensure the fulfillment of children’s rights. The KLA is basically based on fulfilling children’s rights, covering civil rights and freedoms, family environment and alternative care, basic health and welfare, education, usage of leisure time, cultural activities, and special protection. To build a child-friendly district or city requires a village’s existence to realize the fulfillment of a child-friendly city. A child-friendly village (DLA) is a village and sub-district development that brings together the commitment and resources of the village government, the community, and the business community in the framework of fulfilling children’s rights, protecting children from acts of violence, exploitation, and abuse. Hearing children’s opinions, which are planned consciously, comprehensively, and continuously. To create a child-friendly village community, participation in establishing child-friendly homes will greatly influence success in learning child-friendly villages. [ABSTRACT FROM AUTHOR]

Background and aims: At present, evidence on the association between highdensity lipoprotein cholesterol (HDL-C) levels and aggravation of acute pancreatitis (AP) is limited. This study aimed to investigate the relationship between the lowest HDL-C level during intensive care units (ICU) stay and AP aggravation and to determine the optimum cutoff lowest HDL-C level. Methods: Patients admitted to the ICU of the Shandong Provincial Hospital for AP from 2015 to 2021 were included. The lowest HDL-C level during ICU stay was set as the independent variable, and the progression or non-progression to severe AP (SAP) was set as the dependent variable. Univariate and multivariate analyses were performed to determine the relationship between the two variables, and receiver operating characteristic (ROC) curves were plotted to analyze the predictive ability of the lowest HDL-C level for progression to SAP. Results: This study included 115 patients. The difference in the lowest HDL-C level between the SAP and moderately SAP groups was significant (P < 0.05). After adjusting for covariates, the lowest HDL-C level showed a negative correlation with the occurrence of SAP, with a relative risk of 0.897 (95% confidence interval: 0.827–0.973). The area under the ROC curve for prediction of AP aggravation by the lowest HDL-C level was 0.707, and the optimum cutoff lowest HDL-C level was 0.545 mmol/L. Conclusion: No less than 0.545 mmol/L of the HDL-C level during ICU stay may be an independent protective factor for the aggravation of AP. [ABSTRACT FROM AUTHOR]

European countries have made significant progress in strengthening their legal frameworks and policies to prevent and combat child cyberpornography. However, effective prevention and combat efforts require a comprehensive and coordinated approach that involves sharing information and intelligence across borders, cooperating in investigations and prosecutions, and providing support to victims and their families. The research will be conducted using a mixed-methods approach, including both quantitative and qualitative data collection and analysis. The paper, examines the legal measures taken by European countries to prevent and combat child cyberpornography. It analyzes the legal frameworks and policies in different European countries, the challenges faced in implementing and enforcing these legal measures, and the effectiveness of these measures in combatting child cyberpornography. The effectiveness of measures such as age verification, content moderation, and reporting mechanisms will be analyzed to determine their impact on preventing child cyberpornography. Artificial intelligence (AI) technology is also becoming increasingly important in preventing and combatting cyberpornography involving children. From the other side, interstate cooperation can also play a critical role in promoting international education and awareness-raising efforts to prevent child cyberpornography.

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Sudo Jurnal Teknik Informatika is the property of Ilmu Bersama Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

European countries have made significant progress in strengthening their legal frameworks and policies to prevent and combat child cyberpornography. However, effective prevention and combat efforts require a comprehensive and coordinated approach that involves sharing information and intelligence across borders, cooperating in investigations and prosecutions, and providing support to victims and their families. The research will be conducted using a mixed-methods approach, including both quantitative and qualitative data collection and analysis. The paper, examines the legal measures taken by European countries to prevent and combat child cyberpornography. It analyzes the legal frameworks and policies in different European countries, the challenges faced in implementing and enforcing these legal measures, and the effectiveness of these measures in combatting child cyberpornography. The effectiveness of measures such as age verification, content moderation, and reporting mechanisms will be analyzed to determine their impact on preventing child cyberpornography. Artificial intelligence (AI) technology is also becoming increasingly important in preventing and combatting cyberpornography involving children. From the other side, interstate cooperation can also play a critical role in promoting international education and awareness-raising efforts to prevent child cyberpornography. [ABSTRACT FROM AUTHOR]

When it comes to traditional knowledge, such as art, culture, and other types of local wisdom, Indonesia has a lot of potential as an archipelagic nation with many different tribes that each have their own unique traditions, arts, and culture. Its exceptional potential is a national or state asset that has to be safeguarded so that it may continue to grow and ultimately benefit society. In reality, most of the traditional wealth formerly held by residents of the archipelago has either vanished or been moved to other nations. Protecting traditional knowledge via intellectual property rights such as copyrights, patents, plant varieties, industrial designs, and trademarks is an idea that the World Intellectual Property Organization (WIPO) has given considerable thought to. It may be challenging to secure traditional knowledge via intellectual property rights in practice because to problems with ownership, novelty, duration, fixation, invention, and novelty.

Copyright of Araucaria is the property of Araucaria-Revista Iberoamericana de Filosofia, Politica y Humanidades and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Gender-based violence (GBV) is a global social problem that has received considerable attention from policymakers and researchers. However, when speaking of GVB, significant attention is paid to women who are seen as being at the receiving end of violence. Although statistics do support the notion that women are mostly exposed to GBV, little attention has been paid to GBV against men as often not, it is the man who is seen as the aggressor and the woman painted as the victim. This article investigates reasons Gender-Based Violence (GBV) against men is not being addressed in South Africa. Males are also victims of GBV in South Africa, although the government, media, and police pay little attention to GBV against males. It is critical to remember, that men, regardless of their muscularity, can be mistreated by men or women. Males may be raped, killed, or attacked, and they also deserve government care and protection. In South Africa, the government is especially concerned about The GBV against women and children, and August is recognized as Women's Month, where women's rights and protections are vigorously contested. However, in South Africa, nothing is done to protect men from gender-based violence. This article acknowledges violence against women and children in South Africa; however, it contends that the government has done insufficient to combat violence against males in South Africa, even though the constitution guarantees males' human rights and recognizes that they can also be victims of GBV. [ABSTRACT FROM AUTHOR]

The alleviation of landslide impacts is a priority since they have the potential to cause significant economic damage as well as the loss of human life. Mitigation can be achieved effectively by using warning systems and preventive measures. The development of improved methodologies for the analysis and understanding of landslides is at the forefront of this scientific field. Identifying effective monitoring techniques (accurate, fast, and low cost) is the pursued objective. Geographic Information Systems (GISs) and remote sensing techniques are utilized in order to achieve this goal. In this study, four methodological approaches (manual landslide delineation, a segmentation process, and two mapping models, specifically object-based image analysis and pixel-based image analysis (OBIA and PBIA)) were proposed and tested with the use of Unmanned Aerial Vehicles (UAVs) and data analysis methods to showcase the state and evolution of landslides. The digital surface model (DSM)-based classification approach was also used to support the aforementioned approaches. This study focused on streamside landslides at research sites in three different countries: Greece, Romania, and Turkey. The results highlight that the areas of the OBIA-based classifications were the most similar (98%) to our control (manual) classifications for all three sites. The landslides' perimeters at the Lefkothea and Chirlesti sites showed similar results to the OBIA-based classification (93%), as opposed to the Sirtoba site, where the perimeters of the landslides from OBIA-based classification were not well corroborated by the perimeters in the manual classification. Deposition areas that extend beyond the trees were revealed by the DSM-based classification. The results are encouraging because the methodology can be used to monitor landslide evolution with accuracy and high performance in different regions. Specifically, terrains that are difficult to access can be surveyed by UAVs because of their ability to take aerial images. The obtained results provide a framework for the unitary analysis of landslides using modern techniques and tools. [ABSTRACT FROM AUTHOR]

Abstract Background Human rights are best protected, promoted and guaranteed when they can compel binding and enforceability duty. One prominent criticism of category of human rights which includes the human right to health is that it is difficult, to assign the duties that correspond to these rights, because of stark disparity in how the main duty bearers approach their duties. Methods This paper adopts a doctrinal approach to examine and evaluate the duties to the right to health. The method in this study entails a detailed literature search to systematically evaluate the legal implications, regulations, arguments and policy regarding the nature of the obligation to the right to health. This study also engages with normative and philosophical aspects of human rights. Results This paper posits that human rights protect against common, serious, and remediable threats and risks, and ensure that there are remedies from governments and third parties. However, it is difficult to compel duties especially in regard to the right to health. First it is not easy to achieve a uniform standard for duty bearers implied by the words ‘highest attainable physical and mental health.’ Theorists discussed in the paper outline views of what this could mean, from serious to common health concerns. Second, the right to health is not a legally established right in many jurisdictions, making it difficult to enforce. This paper outlines different layers of state and non-state legal duty bearers to enforce the right to health. Conclusion The duty to respect, protect, fulfil and even remedy the right to health, will often be meaningless in practice without a clear identification of the necessary duty bearers to enforce them. The law is the starting point for this to not only enshrine this right as a legally enforceable one but also to clearly identify duty bearers. Without this, the human right to health as outlined under international and regional human rights law generates an implausible, or even impossible, profusion of duties. There remains much work still to be done especially on the moral and legal fronts in order to fully guarantee this right. Trial Registration Not applicable Our work does not report results of a health care intervention on human participants. Registration is therefore not applicable.

Background:In contrast to pediatric Crohn's disease (CD), little is known in pediatric ulcerative colitis (UC) about the relationship between disease phenotype and serologic reactivity to microbial and other antigens. Aim:The aim of this study was to examine disease phenotype and serology in a well-characterized inception cohort of children newly diagnosed with UC during the PROTECT Study (Predicting Response to Standardized Pediatric Colitis Therapy). Methods:Patients were recruited from 29 participating centers. Demographic, clinical, laboratory, and serologic (pANCA, ASCA IgA/IgG, Anti-CBir1, and Anti-OmpC) data were obtained from children 4-17 years old with UC. Results:Sixty-five percent of the patients had positive serology for pANCA, with 62% less than 12 years old and 66% 12 years old or older. Perinuclear anti-neutrophil cytoplasmic antibodies did not correspond to a specific phenotype though pANCA ≥100, found in 19%, was strongly associated with pancolitis (P = 0.003). Anti-CBir1 was positive in 19% and more common in younger children with 32% less than 12 years old as compared with 14% 12 years old or older (P < 0.001). No association was found in any age group between pANCA and Anti-CBir1. Relative rectal sparing was more common in +CBir1, 16% versus 7% (P = 0.02). Calprotectin was lower in Anti-CBir1+ (Median [IQR] 1495 mcg/g [973-3333] vs 2648 mcg/g [1343-4038]; P = 0.04). Vitamin D 25-OH sufficiency was associated with Anti-CBir1+ (P = 0.0009). Conclusions:The frequency of pANCA in children was consistent with adult observations. High titer pANCA was associated with more extensive disease, supporting the idea that the magnitude of immune reactivity may reflect disease severity. Anti-CBir1+ was more common in younger ages, suggesting host-microbial interactions may differ by patient age.

Copyright of Coatings & Protection / Tuceng yu Fanghu is the property of Coating & Protection Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The integration of medical equipment into the Internet of Things (IoT) led to the introduction of Internet of Medical Things (IoMT). Variation of IoT devices have been equipped in medical facilities. These devices provided convenience to healthcare provider since they can continuously monitor their patients in real-time, while allowing them to have greater physical flexibility and mobility. However, users of healthcare services (such as patients and medical staff) often are less concerned about security issues associated with IoT. These alleviate existing problems and jeopardize the lives of their patients by making them susceptible to attacks. Furthermore, IoMT applications have direct access to healthcare services because it handles sensitive patient information. Therefore, it is extremely important to preserve and establish the security and privacy of IoMT. This further justifies the need to investigate and address the related issues. Despite existing literature on security and privacy mechanisms, the domain still requires more attention. Therefore, this paper aims to discuss the security and privacy principles, as well as challenges associated with IoMT. Besides, a comprehensive analysis of privacy and security solutions for IoMT is also presented. In addition, we introduced a novel taxonomy of IoMT security and privacy based on cyber security principles such as “govern,” “protect,” and “detect”. In conclusion, this paper provides a discussion on existing challenges and future direction for researchers.

Desistance theory is premised on the concept that 'people can change' (Maruna, 2017, p. 6). Current desistance discourses evidence a shift in emphasis from the individual narrative to a refocusing that includes the social and structural determinants of the lived experience (Barr and Montgomery, 2016), arguably allowing a more meaningful understanding of personal agency in context. Whilst desistance research explores a range of diverse factors, including Probation Officers' and individuals' perspectives on its impact in achieving better outcomes, desistance as a theoretical approach is contested. Critics argue that a lack of consensus in its conceptualisation and operationalising in practice, along with an over-individualistic focus and broad appropriation across disparate contexts and environments, potentially diminishes its appeal in managerialist contexts (Weaver, 2019). This paper presents findings from a systematic narrative review of the literature regarding probation supervision and desistance. A thematic analysis and narrative synthesis identified four key themes. Firstly, probation supervision offers an opportunity to create a new identity, distanced from an offending past, but this is a complex process that first emerges from an individual's belief in their redeemability. Secondly, supportive relationships are more conducive to fostering desistance than authoritative, surveillance-based approaches; however, some studies identified that when managing risk, aspects of an authoritative approach are necessary. Thirdly, probation services' response to risk influences perspectives of desistance amongst supervisees, with several studies acknowledging the deleterious impacts and associated stigma of criminal justice system involvement. Finally, although included studies appear to indicate the effectiveness of supervision in reducing offending, evidence on what approaches work best, or factors contributing to the quality of experience, is limited. The probation practitioner's approach to the supervisory relationship may play a pivotal role in the desistance narratives of those involved in the criminal justice system. [ABSTRACT FROM AUTHOR]

Aim: It states the practices of mothers with different educational levels to protect their children from cancer. Methods: This descriptive study was conducted in two Family Health Centers between June 2013 and April 2019. The population of the consists of 5640 mothers, with 0-6 age group children registered in family health centers. 359 mothers who met the study criteria were included in the study. A questionnaire was used for data collection. Questionnaire included items about parents' introductory information and mothers' practices to protect their children from cancer were analyzed in five groups (1st group nutrition, 2nd group smoking and harmful chemicals, 3rd group radiation, 4th group medical examinations and immunizations, 5th group sun rays). Results: There is a statistically significant difference between the educational status of the mothers and starting additional foods taking out, the frequency of fruit feeding, the way of eating the fruit, the frequency of feeding ready-made foods and processed meats, applications for smoking, points used in shop and shampoos used in the child’s bathroom, watched television and computer playing time, taking the child to the doctor when he became ill, having all the tests suggested by the doctor, observing the spots on the child’s sunbathing and using the sun cream, observing the spots that cause her to think of herself situations. (p

This research aims to discuss the children's violence that occur in Indonesia. This research using legal research, namely research conducted to produce arguments, new theories or concepts as a prescriptive in solving the problems faced. This research found that the number of cases of violence against children in Indonesia is very high and tends to increase from year to year. To overcome this, it is necessary to create a role model house, namely a house that involves 5 elements (parents, family, community, government, local and state governments) in fulfilling children's rights to prevent violence.

Introduction Although visual impairment appears to be a risk factor for schizophrenia, early blindness may be protective , It’s a phenomenon that has puzzled even the smartest scientific brains for decades. It might surprise you: no person born blind has ever been diagnosed with schizophrenia. Objectives The objective of this research is to discover the relationship between schizophrenia and congenital blindness is there a protective gene ! is that visual perception constitutes an essential stage in the onset of the disease itself ! Methods Case study of a family consisting of thirteen brothers and sisters, three of whom were blind at birth, three with schizophrenia. the study of the files of schizophrenic patients hospitalized in our structure since it opened in the 1970s Results Case study of a family consisting of thirteen brothers and sisters, three of whom were blind at birth, three with schizophrenia, but there is none with blindness at birth and schizophrenia. PLus on the basis of medicals files there is no case of schizophrenia with blindness at birth. Preliminary observational analysis of this clinical case suggests the following hypothesis: the presumed protective role of congenital blindness against schizophrenia. The bibliographic research has objectified three recent studies in this direction in Australia, Denmark, and the USA. Conclusions The relationship between schizophrenia and congenital blindness is still unrecognized and controversial Several studies are done in this direction, but so far there is no assertion or confirmation of the hypothesis Disclosure No significant relationships.

Background: Human rights are best protected, promoted and guaranteed when they can compel binding and enforceability duty. One prominent criticism of category of human rights which includes the human right to health is that it is difficult, to assign the duties that correspond to these rights, because of stark disparity in how the main duty bearers approach their duties. Methods: This paper adopts a doctrinal approach to examine and evaluate the duties to the right to health. The method in this study entails a detailed literature search to systematically evaluate the legal implications, regulations, arguments and policy regarding the nature of the obligation to the right to health. This study also engages with normative and philosophical aspects of human rights. Results: This paper posits that human rights protect against common, serious, and remediable threats and risks, and ensure that there are remedies from governments and third parties. However, it is difficult to compel duties especially in regard to the right to health. First it is not easy to achieve a uniform standard for duty bearers implied by the words 'highest attainable physical and mental health.' Theorists discussed in the paper outline views of what this could mean, from serious to common health concerns. Second, the right to health is not a legally established right in many jurisdictions, making it difficult to enforce. This paper outlines different layers of state and non-state legal duty bearers to enforce the right to health. Conclusion: The duty to respect, protect, fulfil and even remedy the right to health, will often be meaningless in practice without a clear identification of the necessary duty bearers to enforce them. The law is the starting point for this to not only enshrine this right as a legally enforceable one but also to clearly identify duty bearers. Without this, the human right to health as outlined under international and regional human rights law generates an implausible, or even impossible, profusion of duties. There remains much work still to be done especially on the moral and legal fronts in order to fully guarantee this right. Trial Registration: Not applicable Our work does not report results of a health care intervention on human participants. Registration is therefore not applicable. [ABSTRACT FROM AUTHOR]

This article deals with the infectious deseases. Immunisation is a way of preventing infectious diseases. Immunisations are offered to babies, children and adults to protect against serious and preventable diseases. Find out more about getting immunised. It is important to ensure you are up to date with your immunisations. Check with your doctor or nurse to see if you have had all your immunisations. Are your immunisations up to date? [ABSTRACT FROM AUTHOR]

Copyright of Internal Security is the property of Police Academy in Szczytno and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article discusses selected ways of saving energy. It is a review material on the problems of humanity and industry in terms of energy consumption of machines, and devices as well as principles and actions aimed at improving and protecting the environment and the Earth - as our planet. Energy efficiency, which should go hand in hand with energy saving, was also mentioned. A prognosis for the coming years and new ways of labelling devices were presented. In addition, the issue of greenhouse gases and their emissions into the atmosphere was also raised. [ABSTRACT FROM AUTHOR]

The contemporary problems and issues of environmental protection refer to a large extent to problems related - generally speaking - to energy. Currently, the production processes mainly concern the combustion of energy fuels, transport - over long distances, and their use for utility purposes, e.g. engine drive or heating. These processes significantly negatively impact the environment and are magnified by their enormous intensity and size. While energy production and transport processes have been studied for many years, and their results are widely published, the issues related to the application and operation of heating devices are little known and require much observation and research. The operating indicators of heating devices are generally characterized by low values (natural convection), and their artificial increase (intensity) cannot be used due to the acoustic effects and additional (significant) investment costs. The article presents some research results on the intensification of heat flow - i.e. the thermal efficiency of flat heaters placed in a room with a specific temperature. Physical phenomena were investigated numerically by shaping the heat exchange space. The tested systems concerned a room with a free-standing heater, a heater with a vertical panel mounted in parallel, and a system with a curved bottom plate forming the so-called de Laval nozzle. Interesting results of air velocity and temperature fields and values of the heat transfer coefficient along the height of the heater were obtained. Based on the presented research, it can be concluded that the creation of convection surfaces around the heater is advisable because it affects the intensity of heat exchange, which can be increased without energy-intensive energy expenditure, i.e. in a nonmechanical way. Undoubtedly contributes positively to investment and operating costs, which is essential in environmental protection issues. [ABSTRACT FROM AUTHOR]

Objectives: Maintaining physical activity is a modifiable risk factor for dementia. However, older adults do not routinely meet activity guidelines. Online interventions offer a means of engaging with this group and overcoming barriers to physical activity, particularly in the context of a global pandemic where people have become accustomed to at‐home and digital living. This study explored the factors which maximise engagement in an online programme to promote physical activity. Methods: A qualitative study was conducted with adults aged 50 and over, recruited through the online UK PROTECT study cohort. Four focus groups (n = 21) examined key contributors to engagement with a digital programme to promote physical activity. Iterative Categorisation was utilised to identify categories and themes of the focus group data. Semi‐structured interviews were also conducted (n = 5) in which participants were asked to comment on a concept‐stage online intervention. Results: Four key themes emerged from focus group data: interaction at the fore, incentives as foundations, fitting around me and identity is critical. The semi‐structured interviews identified key areas of programme acceptability and specific needs for enhancing engagement. Conclusions: Older adults are open to using online physical activity programmes. Any intervention must be tailored to individual usability preferences and encompass fitness, health and lifestyle needs of older adults. The conceptual‐stage intervention used in this study was found to be acceptable, with key changes needed to maximise engagement. Key points: Maintaining physical activity levels has been identified as a modifiable risk factor in dementia prevention, however, older adults do not routinely meet activity guidelines.A digital intervention could enable older adults to become more active, in order to be effective it is critical to ascertain engagement factors.Digital interventions must be tailored to specific preferences, encompassing fitness, health and lifestyle needs of older adults; feasibility testing will be a priority for any future intervention. [ABSTRACT FROM AUTHOR]

Abstract Background The direct anterior approach for total hip arthroplasty (THA) has specific advantages, but injury to the tensor fasciae lata muscle (TFLM) remains a concern. This injury in part negates some of the advantages of the intermuscular approach, because injury of the muscle fibers of the TFLM can lead to less satisfactory clinical results. Thus, in this study, we propose an intraoperative method to protect the TFLM and demonstrate its feasibility. Methods Fifty-six patients undergoing THA by the direct anterior approach were divided randomly into two groups. In group A, the TFLM was protected by an autogenous tissue “pad” created from the anterior capsule of the joint which protect the TFLM from direct contact with the retractors. In group B, the operation was carried out with no protection of the TFLM except the attempt by the surgeons to consciously avoid injury of the TFLM. We evaluated magnitude of changes in the muscle cross-sectional area (MSCA) and fatty atrophy (FA) by magnetic resonance imaging. The differences in blood hemoglobin and serum levels of myoglobin, lactate dehydrogenase (LDH), and creatine phosphokinase (CPK) were compared at different time, postoperatively. The Harris hip score, postoperative drainage volume and visual analogue scores (VAS) were compared between the two groups. Results LDH, CPK and myoglobin in group B were significantly higher than group A at 8, 24, and 48 h after the surgery. (p

[Introduction] Most of the nuclear power plants under construction and operation in China are coastal sites. According to the previous observation data and analysis, storm surge is the dominant condition in flood control design. There are few research results on tsunami, and there is a lack of engineering experience in the protection methods of structures against tsunami. After the Fukushima nuclear accident, the impact of the tsunami on the safety of nuclear power plants has been widely concerned by nuclear safety supervision, nuclear power practitioners and the public. In China, the tsunami protection level of nuclear power plants in operation has also been reviewed. [Method] Based on the characteristics of tsunami and taking a nuclear power plant in coastal China as an example, this paper carried out the tsunami protection review of nuclear power plant through the physical model test research of tsunami wave. [Result] The model test results show that under the action of tsunami wave, the level elevation of coastal nuclear power plants built in China is adequate for offshore tsunami protection. [Conclusion] Combining with the existing flood control measures in the sea area, further consideration should be given to the protection against possible earthquake and tsunami in Manila and Ryukyu trenches in order to increase the safety margin in the design of the subsequent newly built coastal nuclear power plant in the light of site conditions.

Lead (Pb) is a heavy metal environmental pollutant that can cause functional damage and anemia of immune organs. More and more evidence indicate that the toxicity of lead was related to apoptosis driven by oxidative stress and endoplasmic reticulum stress. This article mainly discusses the protective effect and mechanism of folic acid intervention on lead-induced spleen injury and apoptosis. In this study, Sprague-Dawley rats were randomly divided into control group, lead exposure group (0.2% lead acetate), folic acid + lead group (0.4 mg/kg folic acid and 0.2% lead acetate), and folic acid group (0.4 mg/kg folic acid). By recording and calculating the rat's initial body weight, final body weight, net weight gain, daily weight gain, and spleen index, observe the rat's weight change and spleen weight. And adopt the immunofluorescence staining method to determine the expression level of NrF2, HO-1, GRP78, CHOP protein in the spleen. The results showed that The 0.4 mg/kg folic acid diet did not significantly improve in the body weight and spleen index of lead-exposed rats (P > 0.05). While compared with the control group, the expression levels of HO-1 and CHOP protein were significantly increased in the lead exposure group (P

Ulcerative colitis (UC) is a disabling disease, characterized by chronic inflammation of the colon, with a rising prevalence worldwide in the pediatric age group. Although UC presents in children with varying severity, disease extent, and comorbidities, initial treatment is essentially uniform, consisting of 5-aminosalicylate drugs with corticosteroid induction for those with moderately to severely active disease. With the advent of anti-tumor necrosis factor (TNF) biologic therapy and several new biologics and small-molecule drugs for UC, precision medicine approaches to treatment are needed to more rapidly achieve sustained remission, restore quality of life, normalize development, and limit exposure to toxic corticosteroids in children with UC. Here, we review available data on clinical, biochemical, histopathologic, and molecular predictors of treatment response in UC. We also address known predictors and special treatment considerations in specific relevant scenarios such as very-early-onset UC, acute severe UC, ileal pouch anal anastomosis, and UC with concomitant primary sclerosing cholangitis. The review concludes with a prediction of how machine learning will integrate multimodal patient data to bring precision medicine to the bedside of children with UC in the future.

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Objective and methods: This study examines the protection of workers from the "COVID-19" pandemic, especially healthcare workers, disinfection workers, and future prospects in occupational health. To summarize this concept, I searched the major websites using the key terms "COVID-19," "coronavirus," "pandemic," "workers' health," and "quarantine" or "disinfection." Results and conclusion: The use of disinfectants is recognized to be effective in preventing viruses, but this is also increasing the need to solve problems, such as the side effects caused by the increase in disinfectant use. This paper presents the precautions for safer use of chemicals handled by workers during quarantine and disinfection and proposes policy suggestions. The COVID-19 pandemic will have long-lasting effects on workers. Syndromic methods for monitoring illness outside of healthcare settings can be useful adjuncts to conventional disease reporting. From these results, it is important that the precautions for chemicals' safety handled by workers during quarantine and disinfection as well as policy suggestions for quarantine and disinfection workers are very important to protect workers. [ABSTRACT FROM AUTHOR]

House dust mites and their faecal pellets are the most important indoor allergen causing allergic rhinitis and asthma. Reducing exposure to these allergens will result in relief to allergic persons. Encasement with mite-proof covers (pillow, mattress and quilt) is highly recommended for avoidance of dust mite allergens. The aim of this study is to assess the effectiveness of bed sheets and various mite-proof covers. Six materials were examined by the heat escape method, scanning electron microscope and two-site monoclonal antibody based-ELISA. The results demonstrated leakage of dust mite and its faecal pellets through bed sheets. This was due to such materials having pores larger than the dust mites. Plastic material provided the best protection against dust mite and their allergens but the material was not comfortable when used. Barrier that were made from impermeable cloth are recommended for dust mite allergen avoidance but the leakage of mite allergen through such materials need to be assessed in the laboratory.

Abstract Organ preservation solutions are designed to minimize organ damage during transplantation. A novel preservation solution, WMO-II, was developed to have a low viscosity and to improve microvasculature perfusion for kidneys. In an autologous canine transplantation model, kidney function and recovery were evaluated after organs were flushed and cold-stored with WMO-II or HTK solution, a perfusate currently approved for clinical use. The average number of red blood cells remaining in a single glomerulus after flushing with WMO-II was significantly reduced when compared with HTK solution. Additionally, WMO-II reduced the number of apoptotic bodies in stored kidneys compared to HTK treated tissue after 48 h of cold storage by reducing expression of Caspase-9, BiP, Chop, and Caspase-12. WMO-II solution reduced serum creatinine levels and serum potassium in kidneys stored for 48 h when compared to HTK perfusion. WMO-II preserves kidney function as evidenced by the reduction in serum creatinine and potassium during graft transplantation.