1. Comparison of metastatic phenotypes in mammary tumours of the dog and cat
- Author
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Barbara Brunetti, Giuseppe Sarli, Cinzia Benazzi, Francesca Millanta, Luisa Vera Muscatello, Pietro Asproni, Giancarlo Avallone, Alessandro Poli, L. De Tolla, Germana Beha, BEHA G., MUSCATELLO L. V., BRUNETTI B., ASPRONI P., POLI A., AVALLONE G., DE TOLLA L., MILLANTA F., BENAZZI C., and SARLI G.
- Subjects
Pathology ,medicine.medical_specialty ,General Veterinary ,dog ,METASTASIS ,medicine ,cat ,MAMMARY TUMOUR ,Biology ,Phenotype ,phenothype ,Pathology and Forensic Medicine - Abstract
Forty-eight canine and 57 feline mammary carcinomas with the corresponding lymph node metastasis were available for immunohistochemical analysis using a panel of antibodies (anti-ER, -PR, c-erbB-2, -P63, -CK14, -CK5/6, -CK19). The tumours and metastases were classified, according to a standardized algorithm, into one of the following 5 phenotypes, namely Luminal A and B; non-luminal: c-erbB-2 over-expressing, basal-like, normal-like. Canine primary tumour phenotypes evidenced a higher prevalence of luminal carcinomas (30/48) (P
- Published
- 2015
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