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Objective To explore and practice“rain classroom” in basic medical teaching. Methods Take the undergraduates majoring in Imaging Technology and Biotechnology in the class of 2018 of Dalian Medical University as the research objects Through questionnaire, the teachers and students' feedback on the wisdom teaching of “rain classroom” was investigated, so as to reflect and summarize the auxiliary teaching of “rain classroom”. Results Students believe that “rain classroom” is helpful to their physiology learning and hope to extend this method to use other courses. The teachers impressed on the “rain classroom” exercise answering system,data collection and analysis function which are helpful to understand the learning outcomes of students quantitatively, evaluate the teaching process and adjust the teaching strategy. Conclusions Under the guideline of “Internet +”, “rain classroom” can improve the quality and efficiency of education , encourage students' autonomous learning, promote students' personalized talents training, and thus support the reform of medical education and teaching methodology.